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pirenzepine and Depression, Involutional

pirenzepine has been researched along with Depression, Involutional in 17 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"We measured [(3)H]AF-DX 384 binding in BA 46 and BA 24 from subjects with bipolar disorders (n = 14), major depressive disorders (n = 19), as well as age- and sex-matched controls (n = 19) and the CNS of rats treated with fluoxetine or imipramine."3.83Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants. ( Dean, B; Gibbons, AS; Jeon, WJ; Scarr, E, 2016)
"All charts of patients meeting DSM-IV criteria for bipolar disorder or unipolar major depressive disorder treated with olanzapine in a private psychiatric practice were reviewed and clinical response was assessed retrospectively using the Clinical Global Impression Scale for Improvement (CGI-I)."3.70Does olanzapine have antidepressant properties? A retrospective preliminary study. ( Cherry, EL; Ghaemi, SN; Goodwin, FK; Katzow, JA, 2000)
" However, no correlation between prolactin levels and dosage could be found."1.32[Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics]. ( Fric, M; Laux, G, 2003)
"Converging evidence indicates that, in controlled drug trials, individuals receiving novel antipsychotic medications have fewer adverse effects than those receiving conventional antipsychotic medications."1.31Short report: comparison of patient satisfaction and burden of adverse effects with novel and conventional neuroleptics: a naturalistic study. ( Bromet, EJ; Davidson, M; Rabinowitz, J, 2001)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's14 (82.35)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gibbons, AS1
Jeon, WJ1
Scarr, E1
Dean, B1
Truöl, S1
Von Hippel, C1
Raape, J1
König, F1
Matthews, JD1
Bottonari, KA1
Polania, LM1
Mischoulon, D1
Dording, CM1
Irvin, R1
Fava, M1
Khaldi, S1
Kornreich, C1
Dan, B1
Pelc, I1
Miller, TJ1
Zipursky, RB1
Perkins, D1
Addington, J1
Woods, SW1
Hawkins, KA1
Hoffman, R1
Preda, A1
Epstein, I1
Addington, D1
Lindborg, S1
Marquez, E1
Tohen, M1
Breier, A1
McGlashan, TH1
Detweiler, MB1
Trinkle, DB1
Fric, M1
Laux, G1
Weisler, RH1
Ahearn, EP1
Davidson, JR1
Wallace, CD1
Markowitz, JS1
DeVane, CL1
Schmitt, A1
Braus, DF1
Ghaemi, SN1
Cherry, EL1
Katzow, JA1
Goodwin, FK1
Edell, WS1
Tunis, SL1
Weizman, R1
Weizman, A1
Benazzi, F1
Nelson, EB1
Rielage, E1
Welge, JA1
Keck, PE1
Rabinowitz, J1
Bromet, EJ1
Davidson, M1
Duggal, HS1
Fetchko, J1

Reviews

1 review available for pirenzepine and Depression, Involutional

ArticleYear
Use of atypical antipsychotics in mood disorders.
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:7

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Depres

2001

Trials

3 trials available for pirenzepine and Depression, Involutional

ArticleYear
An open study of olanzapine and fluoxetine for psychotic major depressive disorder: interim analyses.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Depressive Disord

2002
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample.
    Schizophrenia research, 2003, May-01, Volume: 61, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Comorbidity; Depressive

2003
An open trial of olanzapine in the treatment of patients with psychotic depression.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2001, Volume: 13, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Female; Humans; Male; Olan

2001

Other Studies

13 other studies available for pirenzepine and Depression, Involutional

ArticleYear
Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants.
    The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Depressive Diso

2016
[Improvement of tardive dyskinesia after treatment with olanzapine].
    Psychiatrische Praxis, 2002, Volume: 29, Issue:6

    Topics: Affective Disorders, Psychotic; Aged; Benzodiazepines; Depressive Disorder, Major; Drug Therapy, Com

2002
Usefulness of olanzapine in refractory panic attacks.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Drug Resistance; Female; Humans;

2003
Fluoxetine augmentation with olanzapine for treatment of chronic resistant depression in an elderly patient: a case report.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:7

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Depressive Disorder, Major; Dose-Respo

2003
[Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics].
    Psychiatrische Praxis, 2003, Volume: 30 Suppl 2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzothiaze

2003
Adjunctive use of olanzapine in mood disorders: five case reports.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1997, Volume: 9, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Delusions; Depressive Disorder, Majo

1997
Suspected ciprofloxacin inhibition of olanzapine resulting in increased plasma concentration.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:3

    Topics: Anti-Infective Agents; Antipsychotic Agents; Benzodiazepines; Ciprofloxacin; Cytochrome P-450 CYP1A2

1999
[Effective treatment of depressive disorder with psychotic symptoms by olanzapine combination therapy].
    Deutsche medizinische Wochenschrift (1946), 2000, Dec-15, Volume: 125, Issue:50

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Depressive Disorder

2000
Does olanzapine have antidepressant properties? A retrospective preliminary study.
    Bipolar disorders, 2000, Volume: 2, Issue:3 Pt 1

    Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depress

2000
Antipsychotic treatment of behavioral and psychological symptoms of dementia in geropsychiatric inpatients.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2001,Summer, Volume: 9, Issue:3

    Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Depre

2001
Fluoxetine and olanzapine for resistant depression.
    The American journal of psychiatry, 2002, Volume: 159, Issue:1

    Topics: Benzodiazepines; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Fluoxet

2002
Short report: comparison of patient satisfaction and burden of adverse effects with novel and conventional neuroleptics: a naturalistic study.
    Schizophrenia bulletin, 2001, Volume: 27, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder, Majo

2001
Serotonin syndrome and atypical antipsychotics.
    The American journal of psychiatry, 2002, Volume: 159, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major;

2002