pirenzepine has been researched along with Delusional Disorder in 35 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Delusional Disorder: Disorder with presentation of a facade of coldness with characteristic pervasive mistrust and suspiciousness of others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with olanzapine temporally associated weight gain was treated with nizatidine as "add-on" therapy." | 7.70 | H(2) antagonist nizatidine may control olanzapine-associated weight gain in schizophrenic patients. ( Bravi, D; Guarneri, L; Sacchetti, E, 2000) |
| "Olanzapine is an atypical antipsychotic agent whose side effects include sedation, weight gain, and increased creatinine kinase and transaminase levels." | 5.31 | A case report of olanzapine-induced hypersensitivity syndrome. ( Bergman, R; Eilam, O; Hayek, T; Raz, A; Yungerman, T, 2001) |
| "A patient with olanzapine temporally associated weight gain was treated with nizatidine as "add-on" therapy." | 3.70 | H(2) antagonist nizatidine may control olanzapine-associated weight gain in schizophrenic patients. ( Bravi, D; Guarneri, L; Sacchetti, E, 2000) |
| "We report a 2-year experience with olanzapine treatment (20 mg daily) in a 65-year-old male patient with treatment-resistant paranoid schizophrenia, who had previously developed leucopenia and neutropenia first on clozapine and, subsequently, also on risperidone." | 3.70 | Olanzapine appears haematologically safe in patients who developed blood dyscrasia on clozapine and risperidone. ( Dernovsek, MZ; Tavcar, R, 2000) |
| "Olanzapine is an antipsychotic drug that has been on the market since 1996." | 1.31 | Overdose and death with olanzapine: two case reports. ( Cawthon, B; Gerber, JE, 2000) |
| "Olanzapine is an atypical antipsychotic agent whose side effects include sedation, weight gain, and increased creatinine kinase and transaminase levels." | 1.31 | A case report of olanzapine-induced hypersensitivity syndrome. ( Bergman, R; Eilam, O; Hayek, T; Raz, A; Yungerman, T, 2001) |
| "A 21-year-old man with the diagnosis of paranoid schizophrenia was admitted to our clinic with cervical dystonia developing at the end of the first year of olanzapine therapy." | 1.31 | Tardive dystonia associated with olanzapine therapy. ( Afsar, N; Aktan, S; Gunal, DI; Onultan, O, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (34.29) | 18.2507 |
| 2000's | 23 (65.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spivak, B | 1 |
| Alamy, SS | 1 |
| Jarskog, LF | 1 |
| Sheitman, BB | 1 |
| Lieberman, JA | 1 |
| Stoner, SC | 1 |
| Dubisar, BM | 1 |
| Khan, R | 1 |
| Farrar, CD | 1 |
| Grieshaber, S | 1 |
| Jatzko, A | 1 |
| Adler, G | 1 |
| Levy, E | 1 |
| Margolese, HC | 1 |
| Chouinard, G | 1 |
| Poyurovsky, M | 1 |
| Kurs, R | 1 |
| Weizman, A | 2 |
| Kurzthaler, I | 1 |
| Hummer, M | 1 |
| Kohl, C | 1 |
| Miller, C | 1 |
| Fleischhacker, WW | 1 |
| Littrell, KH | 2 |
| Johnson, CG | 2 |
| Littrell, SH | 1 |
| Peabody, CD | 2 |
| Dickson, RA | 1 |
| Dawson, DT | 1 |
| Finkel, B | 1 |
| Lerner, A | 1 |
| Oyffe, I | 1 |
| Rudinski, D | 1 |
| Sigal, M | 1 |
| Landry, P | 1 |
| Cournoyer, J | 1 |
| Moltz, DA | 1 |
| Coeytaux, RR | 1 |
| John, V | 1 |
| Rapp, M | 1 |
| Pies, R | 1 |
| Burkhard, PR | 1 |
| Vingerhoets, FJ | 1 |
| Alberque, C | 1 |
| Landis, T | 1 |
| García López, MM | 1 |
| Ciprés, L | 1 |
| de Cendra, E | 1 |
| Vilalta Franch, J | 1 |
| Lindenmayer, JP | 1 |
| Patel, R | 1 |
| Levenson, JL | 1 |
| Silva, JA | 1 |
| Derecho, DV | 1 |
| Leong, GB | 1 |
| Ferrari, MM | 1 |
| Licht, RW | 1 |
| Olesen, OV | 1 |
| Friis, P | 1 |
| Laustsen, T | 1 |
| Ananth, J | 1 |
| Kenan, J | 1 |
| Zänker, S | 1 |
| Kirchheiner, J | 1 |
| Berghöfer, A | 1 |
| Bolk-Weischedel, D | 1 |
| Sacchetti, E | 1 |
| Guarneri, L | 1 |
| Bravi, D | 1 |
| Nayudu, SK | 1 |
| Scheftner, WA | 1 |
| Dernovsek, MZ | 1 |
| Tavcar, R | 1 |
| Gerber, JE | 1 |
| Cawthon, B | 1 |
| Bressan, RA | 1 |
| Monteiro, VB | 1 |
| Dias, CC | 1 |
| Raz, A | 1 |
| Bergman, R | 1 |
| Eilam, O | 1 |
| Yungerman, T | 1 |
| Hayek, T | 1 |
| Lykouras, L | 1 |
| Gournellis, R | 1 |
| Angelopoulos, E | 1 |
| Jackson, RS | 1 |
| Mouallem, M | 1 |
| Wolf, I | 1 |
| Haapasalo-Pesu, KM | 1 |
| Saarijärvi, S | 1 |
| Petty, RG | 1 |
| Hilligoss, NM | 1 |
| Gunal, DI | 1 |
| Onultan, O | 1 |
| Afsar, N | 1 |
| Aktan, S | 1 |
| Fawcett, RG | 1 |
| Reeves, RR | 1 |
| Torres, RA | 1 |
| Liberto, V | 1 |
| Hart, RH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open Label Trial of Ziprasidone as an Adjuvant for Clozapine- or Olanzapine-Associated Diabetes Mellitus or Impaired Fasting Glucose in Chronic Schizophrenia[NCT00351000] | Phase 4 | 24 participants (Actual) | Interventional | 2005-01-31 | Completed | ||
| The Treatment Efficacy of Combination Atypical Antipsychotics With Sertraline in Patients With Schizophrenia[NCT04076371] | 1,640 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting glucose levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6
| Intervention | mg/dL (Mean) |
|---|---|
| Clozapine Treatment With Adjunctive Ziprasidone | 5 |
| Olanzapine Treatment With Adjunctive Ziprasidone | -4.5 |
Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting insulin levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6
| Intervention | microIU/L (Mean) |
|---|---|
| Clozapine Treatment With Adjunctive Ziprasidone | 1 |
| Olanzapine Treatment With Adjunctive Ziprasidone | -0.9 |
1 review available for pirenzepine and Delusional Disorder
| Article | Year |
|---|---|
[Neuroleptic malignant syndrome associated with olanzapine].
Topics: Antipsychotic Agents; Benzodiazepines; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Ol | 1999 |
34 other studies available for pirenzepine and Delusional Disorder
| Article | Year |
|---|---|
Ziprasidone alternative for olanzapine-induced hyperglycemia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Male | 2002 |
Severe hypertriglyceridemia associated with olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Hospitalization; Humans; Hypertriglyceridemia; Male; O | 2002 |
[Mnestic impairment under olanzapine overdosage in an elderly patient].
Topics: Aged; Amnesia; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Dose-Response Relationship, D | 2002 |
Topiramate produced weight loss following olanzapine-induced weight gain in schizophrenia.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Drug Therapy, Combin | 2002 |
Olanzapine-sertraline combination in schizophrenia with obsessive-compulsive disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Comorbidity; Drug Therapy, Combination; Humans; Middle | 2003 |
Propranolol treatment of olanzapine-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Drug Administration Schedule; | 1997 |
Effects of olanzapine on polydipsia and intermittent hyponatremia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drinking; Female; Humans; Hyponatremia; Olanzapine; Pi | 1997 |
Olanzapine and pregnancy.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzepine; Pregnancy; Pr | 1998 |
Olanzapine treatment in patients with typical and atypical neuroleptic-associated agranulocytosis.
Topics: Adult; Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Clopenthixol; Dose-Response Relations | 1998 |
Acute dystonia with olanzapine.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Dystonia; Female; Humans; Male; Middle Aged; O | 1998 |
Case report: possible neuroleptic malignant syndrome associated with olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Neuroleptic Malignant Syndrome; Olanza | 1998 |
Aggression, agitation, and mania with olanzapine.
Topics: Adult; Aggression; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; | 1998 |
Olanzapine-induced neuroleptic malignant syndrome.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Humans; Neuroleptic Malignant Syndrome; Olanzapine; Pi | 1999 |
Olanzapine-induced ketoacidosis with diabetes mellitus.
Topics: Antipsychotic Agents; Antisocial Personality Disorder; Benzodiazepines; Diabetes Mellitus; Diabetic | 1999 |
Neuroleptic malignant syndrome after the initiation of olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Female; Humans; Middle Aged; Neuroleptic Malignant Syndrome; | 1999 |
Stalking behavior in delusional jealousy.
Topics: Adult; Alcoholism; Antipsychotic Agents; Benzodiazepines; Dangerous Behavior; Delusions; Humans; Jea | 2000 |
Olanzapine serum concentrations lowered by concomitant treatment with carbamazepine.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Drug Interactions; Fe | 2000 |
Tardive dyskinesia associated with olanzapine monotherapy.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dyskinesia, Drug-Induced; Dystonia; Humans; Male; Olan | 1999 |
[Chronic and therapy refractory Fregoli syndrome].
Topics: Antipsychotic Agents; Benzodiazepines; Capgras Syndrome; Chronic Disease; Delusions; Female; Humans; | 2000 |
Healthy outcome under olanzapine treatment in a pregnant woman.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Breast Feeding; Female; Humans; Infant, Newborn; Mater | 2000 |
H(2) antagonist nizatidine may control olanzapine-associated weight gain in schizophrenic patients.
Topics: Adult; Benzodiazepines; Brief Psychiatric Rating Scale; Histamine H2 Antagonists; Humans; Male; Niza | 2000 |
Case report of withdrawal syndrome after olanzapine discontinuation.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Myoclonus; Olanzapine; Pirenzepine; Sc | 2000 |
Olanzapine appears haematologically safe in patients who developed blood dyscrasia on clozapine and risperidone.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Monitoring; Humans; Leukopenia; Male; N | 2000 |
Overdose and death with olanzapine: two case reports.
Topics: Adult; Antipsychotic Agents; Autopsy; Benzodiazepines; Coronary Disease; Drug Overdose; Fatal Outcom | 2000 |
Panic disorder associated with clozapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Olanzapine; Panic Disorder; | 2000 |
A case report of olanzapine-induced hypersensitivity syndrome.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chemical and Drug Induced Liver Injury; Diagnostic Err | 2001 |
Manic symptoms induced by olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Olanzapine; Pirenzep | 2001 |
Continuing treatment with novel antipsychotic drugs despite leukopenia or thrombocytopenia.
Topics: Antipsychotic Agents; Benzodiazepines; Female; Humans; Leukocyte Count; Leukopenia; Middle Aged; Ola | 2001 |
Olanzapine-induced respiratory failure.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzep | 2001 |
Olanzapine induces remarkable weight gain in adolescent patients.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Female; Humans; Male; Olanzapine; Pirenzepine; Ps | 2001 |
Treatment of preexisting diabetes with olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus, Type 2; Drug Administrat | 2001 |
Tardive dystonia associated with olanzapine therapy.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dyskinesia, Drug-Induced; Humans; Male; Olanzapine; Pi | 2001 |
Olanzapine for the treatment of monosymptomatic hypochondriacal psychosis.
Topics: Antipsychotic Agents; Benzodiazepines; Humans; Hypochondriasis; Olanzapine; Pirenzepine; Psychotic D | 2002 |
Atypical neuroleptic malignant syndrome associated with olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Blood Cell Count; Hallucinations; Humans; Male; Middle Aged; | 2002 |