pirenzepine has been researched along with Complication, Postoperative in 10 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 120 patients suffering from brain tumors was included in this study." | 2.66 | [Report of experience with stomach-protective therapy in high-dosage corticosteroid treatment of patients with brain tumors]. ( Hirschl, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tryba, M | 3 |
| Zevounou, F | 2 |
| Grabhoefer, P | 1 |
| Seifert, V | 1 |
| Török, M | 1 |
| Behrens, R | 1 |
| Hofbeck, M | 1 |
| Singer, H | 1 |
| Scharf, J | 1 |
| Rupprecht, T | 1 |
| Urakawa, T | 1 |
| Nagahata, Y | 1 |
| Kawakita, N | 1 |
| Maekawa, N | 1 |
| Nishina, K | 1 |
| Mikawa, K | 1 |
| Shiga, M | 1 |
| Obara, H | 1 |
| Lehot, JJ | 1 |
| Deleat-Besson, R | 1 |
| Bastien, O | 1 |
| Brun, Y | 1 |
| Adeleine, P | 1 |
| Robin, J | 1 |
| Estanove, S | 1 |
| Krakamp, B | 1 |
| Rommel, T | 1 |
| Edelmann, M | 1 |
| Leidig, P | 1 |
| Wruck, G | 1 |
| Hirschl, M | 1 |
| Butti, A | 1 |
| De Giovanni, L | 1 |
| Reggio, D | 1 |
| Valentini, P | 1 |
| Civello, IM | 1 |
10 trials available for pirenzepine and Complication, Postoperative
| Article | Year |
|---|---|
[Prevention of acute stress hemorrhages of the upper gastrointestinal tract with pirenzepine and antacids. A controlled comparison between pirenzepine and cimetidine].
Topics: Antacids; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Critical Care; | 1984 |
Frequency of stress lesions of the upper gastrointestinal tract in paediatric patients after cardiac surgery: effects of prophylaxis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Famotidine; Female; Heart Defects, Congenit | 1994 |
Effect of pirenzepine on postoperative gastric secretion.
Topics: Adult; Aged; Female; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Humans; Male; Midd | 1993 |
Comparison of pirenzepine, ranitidine, and pirenzepine-ranitidine combination for reducing preoperative gastric fluid acidity and volume in children.
Topics: Adolescent; Child; Child, Preschool; Drug Combinations; Gastric Acid; Gastric Acidity Determination; | 1998 |
Should we inhibit gastric acid secretion before cardiac surgery?
Topics: Adult; Aged; Cardiac Surgical Procedures; Female; Gastric Acid; Gastric Acidity Determination; Gastr | 1990 |
[Prevention of stress-induced hemorrhage of the upper gastrointestinal tract in neurosurgical intensive care patients. A controlled, randomized double-blind study with ranitidine alone and in combination with pirenzepine].
Topics: Brain Injuries; Critical Care; Double-Blind Method; Drug Therapy, Combination; Gastric Acidity Deter | 1989 |
Prevention of stress bleeding with ranitidine or pirenzepine and the risk of pneumonia.
Topics: Adult; Aged; Bacterial Infections; Female; Gastric Juice; Gastrointestinal Hemorrhage; Gram-Negative | 1988 |
[Stress bleeding and postoperative pneumonias in intensive care patients on ranitidine or pirenzepine].
Topics: Clinical Trials as Topic; Critical Care; Female; Gastric Acidity Determination; Gastrointestinal Hem | 1988 |
[Report of experience with stomach-protective therapy in high-dosage corticosteroid treatment of patients with brain tumors].
Topics: Administration, Oral; Anti-Ulcer Agents; Brain Edema; Brain Neoplasms; Dexamethasone; Dose-Response | 1988 |
[Use of pirenzepine in prevention of stress ulcers in high-risk surgical patients].
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Female; Humans; Infusio | 1986 |