Page last updated: 2024-11-02

pirenzepine and Chronic Disease

pirenzepine has been researched along with Chronic Disease in 41 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
" In this study, pharmacokinetic interactions and clinical effects of adding the CYP1A2 inhibitor fluvoxamine to steady-state olanzapine was examined in patients suffering from schizophrenia."9.10Fluvoxamine augmentation of olanzapine in chronic schizophrenia: pharmacokinetic interactions and clinical effects. ( Hadjez, J; Härtter, S; Hiemke, C; Jabarin, M; Modai, I; Peled, A; Ritsner, M; Silver, H; Weigmann, H, 2002)
"The aim of this study is to provide long-term data on the effectiveness and safety of olanzapine in a group of patients with severe refractory schizophrenia."9.10Olanzapine for the treatment of chronic refractory schizophrenia: a 12-month follow-up naturalistic study. ( Abel, A; Alvarez, V; Blanco, C; Ciudad, A; Cudeiro, F; Ferreiro, MJ; Gómez, Y; López, A; Peña, C; Prieto, R; Rego, C; Rodríguez-Pérez, V, 2002)
"In a 3-month open-label study, 26 clinically stable patients with schizophrenia taking depot antipsychotics for over 3 years were randomly assigned to continue on their current depot dose or to switch to oral olanzapine."9.10Switching from depot antipsychotic drugs to olanzapine in patients with chronic schizophrenia. ( Godleski, LS; Goldsmith, LJ; Lewis, SJ; Stikovac, DM; Vieweg, WV; Zettwoch, NC, 2003)
"This naturalistic study aimed to determine whether olanzapine and clozapine improve cognitive functioning in a sample of 48 patients with chronic schizophrenia who had either failed to show sufficient clinical improvements or suffered from distressing side effects with conventional antipsychotics and were switched to either olanzapine or clozapine for clinical reasons and, if so, whether the two drugs produce similar or different cognitive effects."9.10Cognitive effects of olanzapine and clozapine treatment in chronic schizophrenia. ( Hughes, C; Kumari, V; Sharma, T; Soni, W, 2003)
"The authors compared the efficacy and safety of three atypical antipsychotics (clozapine, olanzapine, and risperidone) with one another and with haloperidol in the treatment of patients with chronic schizophrenia or schizoaffective disorder."9.10Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder. ( Chakos, M; Citrome, L; Cooper, TB; Czobor, P; Lieberman, JA; Lindenmayer, JP; McEvoy, JP; Sheitman, B; Volavka, J, 2002)
"This randomized double-blind trial was conducted to test the efficacy and safety of olanzapine in Japanese patients with schizophrenia."9.09Olanzapine versus haloperidol in the treatment of patients with chronic schizophrenia: results of the Japan multicenter, double-blind olanzapine trial. ( Inada, T; Ishigooka, J; Miura, S, 2001)
"The effect of an M1-selective muscarinic receptor antagonist telenzepine on lung function was investigated in 18 patients with chronic obstructive bronchitis in a double blind, placebo-controlled, randomized crossover study."9.06An M1-selective muscarinic receptor antagonist telenzepine improves lung function in patients with chronic obstructive bronchitis. ( Cazzola, M; D'Amato, G; Guidetti, E; Kilian, U; Staudinger, H; Steinijans, VW, 1990)
"Recurrence rates of chronic duodenal ulcer after initial therapy with pirenzepine or cimetidine were investigated in a prospective, randomized trial with a total of 80 patients."9.05[Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine]. ( Dufek, W; Hentschel, E; Schütze, K, 1985)
"The purpose of the present study was to compare the effectiveness of pirenzepine and carbenoxolone in accelerating the healing of chronic gastric ulcer."9.05Comparison of pirenzepine and carbenoxolone in the treatment of chronic gastric ulcer. A double-blind endoscopic trial. ( Bianchi Porro, G; Daniotti, S; De Pretis, G; Dobrilla, G; Lazzaroni, M; Mazzacca, G; Petrillo, M; Piai, G; Sabbatini, F, 1985)
"These data demonstrate that, in older patients with schizophrenia and related psychotic disorders, risperidone and olanzapine have approximately equal efficacy in controlling positive symptoms."7.72Comparison of risperidone and olanzapine in the control of negative symptoms of chronic schizophrenia and related psychotic disorders in patients aged 50 to 65 years. ( Breier, A; Feldman, PD; Kaiser, CJ; Kennedy, JS; Sutton, VK; Tollefson, GD; Tran, PV; Zhang, F, 2003)
"We studied the effect of intravenous pirenzepine (3 mg) in normal subjects (n=15, 43+/-16 years old) and in patients with chronic heart failure (n=15, 61+/-12 years old) to assess the effect of low-dose pirenzepine on vagal activity."7.70Paradoxical effects of pirenzepine on parasympathetic activity in chronic heart failure and control. ( Furutani, Y; Hayano, T; Ikeda, Y; Matsuzaki, M; Shimizu, A; Ueyama, T; Yamagata, T; Yamamoto, T, 1999)
"To date only five reports of neuroleptic malignant syndrome (NMS) related to olanzapine exist."7.70Neuroleptic malignant syndrome during olanzapine and levomepromazine treatment. ( Järventausta, K; Leinonen, E, 2000)
"3 mg telenzepine was well tolerated."5.28[Pharmacokinetics and tolerability of telenzepine in patients with compensated liver cirrhosis]. ( Dammann, HG; Müller, P; Reinicke, A; Simon, B, 1990)
" In this study, pharmacokinetic interactions and clinical effects of adding the CYP1A2 inhibitor fluvoxamine to steady-state olanzapine was examined in patients suffering from schizophrenia."5.10Fluvoxamine augmentation of olanzapine in chronic schizophrenia: pharmacokinetic interactions and clinical effects. ( Hadjez, J; Härtter, S; Hiemke, C; Jabarin, M; Modai, I; Peled, A; Ritsner, M; Silver, H; Weigmann, H, 2002)
"The aim of this study is to provide long-term data on the effectiveness and safety of olanzapine in a group of patients with severe refractory schizophrenia."5.10Olanzapine for the treatment of chronic refractory schizophrenia: a 12-month follow-up naturalistic study. ( Abel, A; Alvarez, V; Blanco, C; Ciudad, A; Cudeiro, F; Ferreiro, MJ; Gómez, Y; López, A; Peña, C; Prieto, R; Rego, C; Rodríguez-Pérez, V, 2002)
"In a 3-month open-label study, 26 clinically stable patients with schizophrenia taking depot antipsychotics for over 3 years were randomly assigned to continue on their current depot dose or to switch to oral olanzapine."5.10Switching from depot antipsychotic drugs to olanzapine in patients with chronic schizophrenia. ( Godleski, LS; Goldsmith, LJ; Lewis, SJ; Stikovac, DM; Vieweg, WV; Zettwoch, NC, 2003)
"This naturalistic study aimed to determine whether olanzapine and clozapine improve cognitive functioning in a sample of 48 patients with chronic schizophrenia who had either failed to show sufficient clinical improvements or suffered from distressing side effects with conventional antipsychotics and were switched to either olanzapine or clozapine for clinical reasons and, if so, whether the two drugs produce similar or different cognitive effects."5.10Cognitive effects of olanzapine and clozapine treatment in chronic schizophrenia. ( Hughes, C; Kumari, V; Sharma, T; Soni, W, 2003)
"The authors compared the efficacy and safety of three atypical antipsychotics (clozapine, olanzapine, and risperidone) with one another and with haloperidol in the treatment of patients with chronic schizophrenia or schizoaffective disorder."5.10Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder. ( Chakos, M; Citrome, L; Cooper, TB; Czobor, P; Lieberman, JA; Lindenmayer, JP; McEvoy, JP; Sheitman, B; Volavka, J, 2002)
"This randomized double-blind trial was conducted to test the efficacy and safety of olanzapine in Japanese patients with schizophrenia."5.09Olanzapine versus haloperidol in the treatment of patients with chronic schizophrenia: results of the Japan multicenter, double-blind olanzapine trial. ( Inada, T; Ishigooka, J; Miura, S, 2001)
"The effect of an M1-selective muscarinic receptor antagonist telenzepine on lung function was investigated in 18 patients with chronic obstructive bronchitis in a double blind, placebo-controlled, randomized crossover study."5.06An M1-selective muscarinic receptor antagonist telenzepine improves lung function in patients with chronic obstructive bronchitis. ( Cazzola, M; D'Amato, G; Guidetti, E; Kilian, U; Staudinger, H; Steinijans, VW, 1990)
"Recurrence rates of chronic duodenal ulcer after initial therapy with pirenzepine or cimetidine were investigated in a prospective, randomized trial with a total of 80 patients."5.05[Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine]. ( Dufek, W; Hentschel, E; Schütze, K, 1985)
"The purpose of the present study was to compare the effectiveness of pirenzepine and carbenoxolone in accelerating the healing of chronic gastric ulcer."5.05Comparison of pirenzepine and carbenoxolone in the treatment of chronic gastric ulcer. A double-blind endoscopic trial. ( Bianchi Porro, G; Daniotti, S; De Pretis, G; Dobrilla, G; Lazzaroni, M; Mazzacca, G; Petrillo, M; Piai, G; Sabbatini, F, 1985)
"The unprecedented level of activity in the development of new antipsychotic medications can be traced to the 1989 approval of clozapine by the US Food and Drug Administration for treatment of refractory schizophrenia."4.79New antipsychotic medications: strategies for evaluation and selected findings. ( Schooler, NR, 1997)
"These data demonstrate that, in older patients with schizophrenia and related psychotic disorders, risperidone and olanzapine have approximately equal efficacy in controlling positive symptoms."3.72Comparison of risperidone and olanzapine in the control of negative symptoms of chronic schizophrenia and related psychotic disorders in patients aged 50 to 65 years. ( Breier, A; Feldman, PD; Kaiser, CJ; Kennedy, JS; Sutton, VK; Tollefson, GD; Tran, PV; Zhang, F, 2003)
"By using Israel's National Psychiatric Hospitalization Case Registry, rehospitalization status was monitored for all patients with schizophrenia who were discharged from any inpatient psychiatric facility in Israel while taking risperidone (N=268) or olanzapine (N=313) between Jan."3.71Rehospitalization rates of chronically ill schizophrenic patients discharged on a regimen of risperidone, olanzapine, or conventional antipsychotics. ( Davidson, M; Kaplan, Z; Lichtenberg, P; Mark, M; Nahon, D; Rabinowitz, J, 2001)
"Clozapine was reserved for more severe forms of schizophrenia, but its cost impact was relatively low."3.71Service use and costs of treating schizophrenia with atypical antipsychotics. ( Frangou, S; Lewis, M; McCrone, P, 2001)
"Glutamate concentrations were measured in serum and were estimated (Glx/Cr) in cingulate cortex by proton magnetic resonance spectroscopy (MRS) in schizophrenia patients while they were being treated with conventional neuroleptics and then 8 weeks after switching to olanzapine."3.71Modulation of brain and serum glutamatergic concentrations following a switch from conventional neuroleptics to olanzapine. ( Evins, AE; Goff, DC; Hennen, J; Lyoo, IK; Renshaw, PF; Tsai, G; Wald, LL; Yurgelun-Todd, DA, 2002)
"We studied the effect of intravenous pirenzepine (3 mg) in normal subjects (n=15, 43+/-16 years old) and in patients with chronic heart failure (n=15, 61+/-12 years old) to assess the effect of low-dose pirenzepine on vagal activity."3.70Paradoxical effects of pirenzepine on parasympathetic activity in chronic heart failure and control. ( Furutani, Y; Hayano, T; Ikeda, Y; Matsuzaki, M; Shimizu, A; Ueyama, T; Yamagata, T; Yamamoto, T, 1999)
"To date only five reports of neuroleptic malignant syndrome (NMS) related to olanzapine exist."3.70Neuroleptic malignant syndrome during olanzapine and levomepromazine treatment. ( Järventausta, K; Leinonen, E, 2000)
"Chronic alcoholic gastritis is a very important social problem in the Health District of Arezzo, which covers an area where wine is an integral part of the diet."2.66[Alcoholic gastropathy. Notes on its epidemiology and the therapeutic experience using pirenzepine]. ( Agnolucci, A; Angioli, D; Caneschi, F; Cucinelli, ML; Magnolfi, F; Pichi, V; Rossi, G; Valentini, P, 1986)
"3 mg telenzepine was well tolerated."1.28[Pharmacokinetics and tolerability of telenzepine in patients with compensated liver cirrhosis]. ( Dammann, HG; Müller, P; Reinicke, A; Simon, B, 1990)
" Plasma concentrations remained in the therapeutic range and the dosage regimen was well tolerated."1.28Steady-state intravenous pharmacokinetics of pirenzepine in patients with hepatic insufficiency and combined renal- and hepatic insufficiency. ( Bozler, G; Krakamp, B; Leidig, P; Schmitz, R; Tanswell, P; Vogel, H, 1989)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19909 (21.95)18.7374
1990's8 (19.51)18.2507
2000's24 (58.54)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Silberstein, SD1
Peres, MF1
Hopkins, MM1
Shechter, AL1
Young, WB1
Rozen, TD1
Mahendran, R1
Hiemke, C1
Peled, A1
Jabarin, M1
Hadjez, J1
Weigmann, H1
Härtter, S1
Modai, I1
Ritsner, M1
Silver, H1
Grieshaber, S1
Jatzko, A1
Adler, G1
Rodríguez-Pérez, V1
López, A3
Blanco, C1
Peña, C1
Abel, A1
Gómez, Y1
Ferreiro, MJ1
Rego, C1
Cudeiro, F1
Alvarez, V1
Prieto, R1
Ciudad, A1
Godleski, LS1
Goldsmith, LJ1
Vieweg, WV1
Zettwoch, NC1
Stikovac, DM1
Lewis, SJ1
Maguire, GA1
Phillips, G1
Sharma, T1
Hughes, C1
Soni, W1
Kumari, V1
Freudenreich, O1
Detweiler, MB1
Trinkle, DB1
Gorski, ED1
Willis, KC1
Feldman, PD1
Kaiser, CJ1
Kennedy, JS1
Sutton, VK1
Tran, PV1
Tollefson, GD1
Zhang, F1
Breier, A1
Grigor'ev, PIa1
Khar'kovskiĭ, NN1
Elina, NA1
El'tsova, NB1
Elisova, NV1
Kalinin, AV1
Loginov, AF1
Antokhin, EA1
Sheitman, BB1
Lindgren, JC1
Early, J1
Sved, M1
Schooler, NR1
John, V1
Rapp, M1
Pies, R1
Hayano, T1
Shimizu, A1
Ikeda, Y1
Yamamoto, T1
Yamagata, T1
Ueyama, T1
Furutani, Y1
Matsuzaki, M1
Marcus, EL1
Vass, A1
Zislin, J1
Zänker, S1
Khan, M1
Farver, D1
Järventausta, K1
Leinonen, E1
Hagger, R1
Brown, C1
Hurley, P1
Rabinowitz, J1
Lichtenberg, P1
Kaplan, Z1
Mark, M1
Nahon, D1
Davidson, M1
Cuesta, MJ1
Peralta, V1
Zarzuela, A1
Ishigooka, J1
Inada, T1
Miura, S1
Smith, RC1
Infante, M1
Singh, A1
Khandat, A1
Lewis, M1
McCrone, P1
Frangou, S1
Volavka, J1
Czobor, P1
Sheitman, B1
Lindenmayer, JP1
Citrome, L1
McEvoy, JP1
Cooper, TB1
Chakos, M1
Lieberman, JA1
Goff, DC1
Hennen, J1
Lyoo, IK1
Tsai, G1
Wald, LL1
Evins, AE1
Yurgelun-Todd, DA1
Renshaw, PF1
Markianos, M1
Hatzimanolis, J1
Lykouras, L1
Christodoulou, GN1
Reinicke, A1
Müller, P1
Dammann, HG1
Simon, B1
Cazzola, M1
D'Amato, G1
Guidetti, E1
Staudinger, H1
Steinijans, VW1
Kilian, U1
Saakian, Ag1
Krakamp, B1
Tanswell, P1
Leidig, P1
Vogel, H1
Schmitz, R1
Bozler, G1
Magnolfi, F1
Agnolucci, A1
Rossi, G1
Caneschi, F1
Pichi, V1
Cucinelli, ML1
Valentini, P1
Angioli, D1
Guslandi, M2
Masci, E1
Ballarin, E2
Imbimbo, BP1
Daniotti, S3
Geller, LI1
Amatiak, AG1
Bessonova, GA1
Basilico, M1
Tittobello, A1
Hentschel, E1
Schütze, K1
Dufek, W1
Bianchi Porro, G1
Petrillo, M1
Lazzaroni, M1
Mazzacca, G1
Sabbatini, F1
Piai, G1
Dobrilla, G1
De Pretis, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070]68 participants (Actual)Interventional2007-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for pirenzepine and Chronic Disease

ArticleYear
Optimal dosing of medications (in bipolar disorder).
    The Journal of family practice, 2003, Volume: Suppl

    Topics: Acute Disease; Affect; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Ch

2003
New antipsychotic medications: strategies for evaluation and selected findings.
    Schizophrenia research, 1997, Oct-30, Volume: 27, Issue:2-3

    Topics: Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic; Clozapine; Drug Ad

1997
Rapid resolution of antipsychotic-induced tardive dyskinesia with olanzapine.
    South Dakota journal of medicine, 2000, Volume: 53, Issue:2

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Chronic Disease; Dysk

2000
Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: a longitudinal study.
    Schizophrenia research, 2001, Mar-01, Volume: 48, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Cognition; Female; Humans; Longitudin

2001

Trials

14 trials available for pirenzepine and Chronic Disease

ArticleYear
Fluvoxamine augmentation of olanzapine in chronic schizophrenia: pharmacokinetic interactions and clinical effects.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:5

    Topics: Adult; Benzodiazepines; Chemotherapy, Adjuvant; Chronic Disease; Drug Interactions; Female; Fluvoxam

2002
Olanzapine for the treatment of chronic refractory schizophrenia: a 12-month follow-up naturalistic study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:6

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Body Weight; Chronic Disease; Drug Re

2002
Switching from depot antipsychotic drugs to olanzapine in patients with chronic schizophrenia.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Chronic Diseas

2003
Cognitive effects of olanzapine and clozapine treatment in chronic schizophrenia.
    Psychopharmacology, 2003, Volume: 169, Issue:3-4

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Cogn

2003
Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: a longitudinal study.
    Schizophrenia research, 2001, Mar-01, Volume: 48, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Cognition; Female; Humans; Longitudin

2001
Olanzapine versus haloperidol in the treatment of patients with chronic schizophrenia: results of the Japan multicenter, double-blind olanzapine trial.
    Psychiatry and clinical neurosciences, 2001, Volume: 55, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Double-Blind

2001
The effects of olanzapine on neurocognitive functioning in medication-refractory schizophrenia.
    The international journal of neuropsychopharmacology, 2001, Volume: 4, Issue:3

    Topics: Antipsychotic Agents; Benzodiazepines; Chronic Disease; Cognition; Double-Blind Method; Dyskinesia,

2001
Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder.
    The American journal of psychiatry, 2002, Volume: 159, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Double-Blind M

2002
An M1-selective muscarinic receptor antagonist telenzepine improves lung function in patients with chronic obstructive bronchitis.
    Pulmonary pharmacology, 1990, Volume: 3, Issue:4

    Topics: Administration, Oral; Adult; Aged; Biometry; Bronchitis; Chronic Disease; Double-Blind Method; Femal

1990
[Alcoholic gastropathy. Notes on its epidemiology and the therapeutic experience using pirenzepine].
    Minerva medica, 1986, Oct-13, Volume: 77, Issue:39

    Topics: Adult; Aged; Alcoholism; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Gas

1986
Luminal bicarbonate outflow in chronic antral erosions is suppressed by pirenzepine.
    Hepato-gastroenterology, 1987, Volume: 34, Issue:4

    Topics: Adult; Aged; Bicarbonates; Chronic Disease; Double-Blind Method; Female; Gastric Mucosa; Humans; Mal

1987
Pirenzepine in erosive duodenitis. A controlled clinical trial versus ranitidine.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:6

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Chronic Disease; Clinical Trials as Topic; Double

1985
[Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine].
    Zeitschrift fur Gastroenterologie, 1985, Volume: 23, Issue:1

    Topics: Adult; Aged; Benzodiazepinones; Chronic Disease; Cimetidine; Clinical Trials as Topic; Duodenal Ulce

1985
Comparison of pirenzepine and carbenoxolone in the treatment of chronic gastric ulcer. A double-blind endoscopic trial.
    Hepato-gastroenterology, 1985, Volume: 32, Issue:6

    Topics: Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Chronic Disease; Clinical Trials as Topic; Doub

1985

Other Studies

24 other studies available for pirenzepine and Chronic Disease

ArticleYear
Olanzapine in the treatment of refractory migraine and chronic daily headache.
    Headache, 2002, Volume: 42, Issue:6

    Topics: Antipsychotic Agents; Benzodiazepines; Chronic Disease; Female; Headache Disorders; Humans; Male; Mi

2002
Emergence of compulsive symptoms with olanzapine treatment.
    The Australian and New Zealand journal of psychiatry, 2002, Volume: 36, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Humans; Male; Obsessive-Compulsive Di

2002
[Mnestic impairment under olanzapine overdosage in an elderly patient].
    Psychiatrische Praxis, 2002, Volume: 29, Issue:8

    Topics: Aged; Amnesia; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Dose-Response Relationship, D

2002
Treatment noncompliance with orally disintegrating olanzapine tablets.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2003, Volume: 48, Issue:5

    Topics: Administration, Oral; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Female; Humans; Middle

2003
Fluoxetine augmentation with olanzapine for treatment of chronic resistant depression in an elderly patient: a case report.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:7

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Depressive Disorder, Major; Dose-Respo

2003
Report of three case studies with olanzapine for chronic pain.
    The journal of pain, 2003, Volume: 4, Issue:3

    Topics: Analgesics, Non-Narcotic; Benzodiazepines; Chronic Disease; Female; Humans; Middle Aged; Olanzapine;

2003
Comparison of risperidone and olanzapine in the control of negative symptoms of chronic schizophrenia and related psychotic disorders in patients aged 50 to 65 years.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:9

    Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Depression; Double

2003
[Treatment of peptic ulcer with gastrozepin].
    Sovetskaia meditsina, 1984, Issue:1

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Chronic Disease; Drug Evaluation; Female; Humans;

1984
[The possibilities of using gastrotsepin in treating digestive organ diseases].
    Voenno-meditsinskii zhurnal, 1993, Issue:6

    Topics: Acute Disease; Adult; Antacids; Anti-Ulcer Agents; Chronic Disease; Digestive System Diseases; Drug

1993
High-dose olanzapine for treatment-refractory schizophrenia.
    The American journal of psychiatry, 1997, Volume: 154, Issue:11

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Chronic Disease; Drug Administ

1997
Aggression, agitation, and mania with olanzapine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:10

    Topics: Adult; Aggression; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder;

1998
Paradoxical effects of pirenzepine on parasympathetic activity in chronic heart failure and control.
    International journal of cardiology, 1999, Volume: 68, Issue:1

    Topics: Adult; Analysis of Variance; Case-Control Studies; Chronic Disease; Echocardiography; Female; Heart

1999
Marked elevation of serum creatine kinase associated with olanzapine therapy.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:6

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Creatine Kinase; Humans; Male; Olanza

1999
[Chronic and therapy refractory Fregoli syndrome].
    Psychiatrische Praxis, 2000, Volume: 27, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Capgras Syndrome; Chronic Disease; Delusions; Female; Humans;

2000
Neuroleptic malignant syndrome during olanzapine and levomepromazine treatment.
    Acta psychiatrica Scandinavica, 2000, Volume: 102, Issue:3

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Female; Humans; Methotrimeprazine; Neu

2000
Olanzapine and pancreatitis.
    The British journal of psychiatry : the journal of mental science, 2000, Volume: 177

    Topics: Adult; Alcohol Drinking; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Humans; Male; Olanz

2000
Rehospitalization rates of chronically ill schizophrenic patients discharged on a regimen of risperidone, olanzapine, or conventional antipsychotics.
    The American journal of psychiatry, 2001, Volume: 158, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Female; Hospitalization; Humans; Isra

2001
Service use and costs of treating schizophrenia with atypical antipsychotics.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:10

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Cost-Benefit Analysis; Dos

2001
Modulation of brain and serum glutamatergic concentrations following a switch from conventional neuroleptics to olanzapine.
    Biological psychiatry, 2002, Mar-15, Volume: 51, Issue:6

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Creatine; Female; Glutamic Acid; Gyru

2002
Prolactin responses to acute clomipramine and haloperidol of male schizophrenic patients in a drug-free state and after treatment with clozapine or with olanzapine.
    Schizophrenia research, 2002, Jul-01, Volume: 56, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clomipramine; Clozapine; Haloperidol;

2002
[Pharmacokinetics and tolerability of telenzepine in patients with compensated liver cirrhosis].
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:11

    Topics: Adolescent; Adult; Chronic Disease; Half-Life; Humans; Liver Cirrhosis; Middle Aged; Parasympatholyt

1990
[Effect of gastrozepin on the rate of gastric emptying in patients with peptic ulcer and dumping syndrome following gastric resection].
    Klinicheskaia meditsina, 1985, Volume: 63, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Chronic Disease; Drug Evaluation; Dumping Syn

1985
Steady-state intravenous pharmacokinetics of pirenzepine in patients with hepatic insufficiency and combined renal- and hepatic insufficiency.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:1

    Topics: Adult; Aged; Chronic Disease; Female; Half-Life; Humans; Kidney Diseases; Liver Cirrhosis; Liver Dis

1989
[Gastrozepin and gordox in the treatment of chronic pancreatitis].
    Sovetskaia meditsina, 1986, Issue:7

    Topics: Adult; Aprotinin; Chronic Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pan

1986