pirenzepine has been researched along with Bipolar Disorder in 129 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate effects of olanzapine in diverse exacerbations of bipolar disorders." | 9.10 | Olanzapine in diverse syndromal and subsyndromal exacerbations of bipolar disorders. ( Das, B; Janenawasin, S; Ketter, TA; Lembke, A; Mongkolcheep, J; Santosa, CM; Schumacher, M; Wang, PW, 2002) |
| "To examine the use of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression." | 9.10 | Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. ( Baker, RW; Beymer, K; Bowden, C; Breier, A; Calabrese, J; Centorrino, F; Dube, S; Evans, AR; Ketter, TA; Mitchell, PB; Risser, R; Sachs, G; Tohen, M; Tollefson, GD; Vieta, E, 2003) |
| "This study compared the efficacy, safety, and tolerability of divalproex and olanzapine in the treatment of acute mania associated with bipolar disorder." | 9.10 | A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder. ( Sachs, G; Sommerville, KW; Swann, AC; Weisler, R; Wozniak, P; Zajecka, JM, 2002) |
| "The aim of this study was to estimate the long-term effectiveness of olanzapine as adjunctive therapy in patients with bipolar disorder who exhibited an inadequate response to mood stabilizers." | 9.09 | Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder. ( Benabarre, A; Colom, F; Corbella, B; Gastó, C; Gilaberte, I; Martínez-Arán, A; Reinares, M; Tohen, M; Vieta, E, 2001) |
| "These results suggest that the efficacy and tolerability of risperidone, olanzapine, and clozapine are similar in patients with bipolar disorder." | 9.09 | A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder. ( Ghaemi, SN; Guille, C; Sachs, GS, 2000) |
| "Open-label olanzapine treatment was efficacious and well tolerated in the treatment of acute mania in youths with bipolar disorder." | 9.09 | A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder. ( Biederman, J; Feldman, PD; Frazier, JA; Garfield, SB; Gonzalez-Heydrich, J; Jacobs, TG; Kim, GS; Nowlin, ZM; Rater, MA; Risser, RC; Sohma, M; Tarazi, RA; Tohen, M; Toma, V, 2001) |
| "Olanzapine may have antimanic and mood-stabilizing effects in some patients with bipolar disorder, and is generally well tolerated." | 9.08 | Olanzapine in treatment-resistant bipolar disorder. ( Altshuler, L; Denicoff, K; Frye, M; Keck, PE; Kmetz, GF; Kupka, R; Leverich, GS; McElroy, SL; Nolen, W; Post, RM; Suppes, T, 1998) |
| "Previous studies have examined the safety and tolerability of oral-loaded divalproex sodium in the treatment of acute mania, but not the early efficacy of this dosing strategy." | 7.80 | The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder. ( Baker, JD; Hirschfeld, RM; Sommerville, KW; Tracy, K; Wozniak, P, 2003) |
| "The present paper describes a case of serotonin syndrome (SS), which developed in a patient with bipolar affective disorder after the addition of olanzapine to her regimen of lithium and citalopram." | 7.71 | Can olanzapine be implicated in causing serotonin syndrome? ( Haslett, CD; Kumar, S, 2002) |
| " This resistant case of lethal catatonia responded selectively to high-dose olanzapine treatment." | 7.71 | Lethal catatonia responding to high-dose olanzapine therapy. ( Cassidy, EM; Finucane, J; O'Brien, M; O'Keane, V; Osman, MF, 2001) |
| "To report a case of neuroleptic malignant syndrome (NMS) associated with the use of olanzapine." | 7.70 | Neuroleptic malignant syndrome associated with olanzapine. ( Billington, CJ; Ercan-Fang, N; Filice, GA; McDougall, BC, 1998) |
| "Classic neuroleptic malignant syndrome (NMS) was diagnosed." | 6.42 | Neuroleptic malignant syndrome in an adolescent receiving olanzapine-lithium combination therapy. ( Berry, N; Gupta, SK; Pradhan, S; Sagar, R, 2003) |
| "We aimed to compare clinical outcomes, health-related quality of life (HRQOL) and work status associated with olanzapine and haloperidol treatment in patients with bipolar disorder." | 5.10 | Olanzapine versus haloperidol in the treatment of acute mania: clinical outcomes, health-related quality of life and work status. ( Breier, A; Edgell, ET; Gandhi, G; Haro, JM; Namjoshi, MA; Shi, L; Tohen, M; Zhang, F, 2002) |
| " The aim of this study is to determine the effectiveness and safety of olanzapine as an add-on therapy in patients with bipolar disorder with a rapid cycling course during a dysphoric mania episode." | 5.10 | Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapine. ( Fernandez-Corres, B; Gonzalez-Pinto, A; Gutierrez, M; Lalaguna, B; Micó, JA; Pérez-Heredia, JL; Tohen, M, 2002) |
| "To evaluate effects of olanzapine in diverse exacerbations of bipolar disorders." | 5.10 | Olanzapine in diverse syndromal and subsyndromal exacerbations of bipolar disorders. ( Das, B; Janenawasin, S; Ketter, TA; Lembke, A; Mongkolcheep, J; Santosa, CM; Schumacher, M; Wang, PW, 2002) |
| "Randomized controlled trials have demonstrated the efficacy of olanzapine for treating acute mania or depression symptoms in patients with bipolar disorder." | 5.10 | The efficacy of olanzapine monotherapy for acute hypomania or mania in an outpatient setting. ( Dennehy, EB; Doyle, K; Suppes, T, 2003) |
| "This study compared the efficacy, safety, and tolerability of divalproex and olanzapine in the treatment of acute mania associated with bipolar disorder." | 5.10 | A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder. ( Sachs, G; Sommerville, KW; Swann, AC; Weisler, R; Wozniak, P; Zajecka, JM, 2002) |
| " In 3 double-blind studies, acutely agitated patients with schizophrenia (N = 311), bipolar mania (N = 201), or dementia (N = 206) were treated with intramuscular (1-3 injections/24 hrs) olanzapine (2." | 5.10 | Calming versus sedative effects of intramuscular olanzapine in agitated patients. ( Alaka, K; Battaglia, J; Lindborg, SR; Meehan, K; Wright, P, 2003) |
| "This 47-week, randomized, double-blind study compared flexibly dosed olanzapine (5-20 mg/day) to divalproex (500-2500 mg/day) for manic or mixed episodes of bipolar disorder (N=251)." | 5.10 | Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study. ( Altshuler, L; Baker, RW; Brown, E; Frye, M; Ketter, TA; Risser, RC; Schuh, LM; Suppes, T; Tohen, M; Zajecka, J; Zarate, CA, 2003) |
| "To examine the use of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression." | 5.10 | Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. ( Baker, RW; Beymer, K; Bowden, C; Breier, A; Calabrese, J; Centorrino, F; Dube, S; Evans, AR; Ketter, TA; Mitchell, PB; Risser, R; Sachs, G; Tohen, M; Tollefson, GD; Vieta, E, 2003) |
| "These results suggest that the efficacy and tolerability of risperidone, olanzapine, and clozapine are similar in patients with bipolar disorder." | 5.09 | A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder. ( Ghaemi, SN; Guille, C; Sachs, GS, 2000) |
| "During up to 1 year of olanzapine therapy, either as monotherapy or in combination with lithium and/or fluoxetine, patients with bipolar disorder demonstrated significant improvement in mania and depression symptoms with a favorable safety profile." | 5.09 | Long-term olanzapine therapy in the treatment of bipolar I disorder: an open-label continuation phase study. ( Gibson, PJ; Greaney, MG; Grundy, SL; Namjoshi, MA; Sanger, TM; Tohen, MF, 2001) |
| ", who received at least 6 weeks of add-on olanzapine treatment for psychotic mood disorders (schizoaffective disorders [bipolar and depressive type], bipolar disorders [I, II, and NOS], and major depressive disorder)." | 5.09 | Olanzapine therapy in treatment-resistant psychotic mood disorders: a long-term follow-up study. ( Grace, JJ; Narendran, R; Pato, MT; Pristach, CA; Valenti, AM; Young, CM, 2001) |
| "The aim of this study was to estimate the long-term effectiveness of olanzapine as adjunctive therapy in patients with bipolar disorder who exhibited an inadequate response to mood stabilizers." | 5.09 | Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder. ( Benabarre, A; Colom, F; Corbella, B; Gastó, C; Gilaberte, I; Martínez-Arán, A; Reinares, M; Tohen, M; Vieta, E, 2001) |
| "Open-label olanzapine treatment was efficacious and well tolerated in the treatment of acute mania in youths with bipolar disorder." | 5.09 | A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder. ( Biederman, J; Feldman, PD; Frazier, JA; Garfield, SB; Gonzalez-Heydrich, J; Jacobs, TG; Kim, GS; Nowlin, ZM; Rater, MA; Risser, RC; Sohma, M; Tarazi, RA; Tohen, M; Toma, V, 2001) |
| " A total of 115 patients with a DSM-IV diagnosis of bipolar disorder, manic or mixed, were randomized to olanzapine, 5 to 20 mg/d (n = 55), or placebo (n = 60)." | 5.09 | Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group. ( Banov, MC; Breier, A; Francis, J; Grundy, SL; Jacobs, TG; Janicak, PG; McElroy, SL; Risser, R; Sanger, T; Tohen, M; Tollefson, GD; Toma, V; Zhang, F, 2000) |
| "Olanzapine may have antimanic and mood-stabilizing effects in some patients with bipolar disorder, and is generally well tolerated." | 5.08 | Olanzapine in treatment-resistant bipolar disorder. ( Altshuler, L; Denicoff, K; Frye, M; Keck, PE; Kmetz, GF; Kupka, R; Leverich, GS; McElroy, SL; Nolen, W; Post, RM; Suppes, T, 1998) |
| "The role of lithium carbonate in the maintenance treatment of bipolar disorder is well established." | 4.82 | Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder. ( Freeman, MP; Gelenberg, AJ; Gnanadesikan, M, 2003) |
| "Compared with controls, [(3)H]AF-DX 384 binding was lower in BA 24 and BA 46 in bipolar disorders and major depressive disorders, while CHRM2 protein and oxotremorine-M stimulated [(35)S]GTPγS binding was only lower in BA 24." | 3.83 | Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants. ( Dean, B; Gibbons, AS; Jeon, WJ; Scarr, E, 2016) |
| "Previous studies have examined the safety and tolerability of oral-loaded divalproex sodium in the treatment of acute mania, but not the early efficacy of this dosing strategy." | 3.80 | The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder. ( Baker, JD; Hirschfeld, RM; Sommerville, KW; Tracy, K; Wozniak, P, 2003) |
| "The present paper describes a case of serotonin syndrome (SS), which developed in a patient with bipolar affective disorder after the addition of olanzapine to her regimen of lithium and citalopram." | 3.71 | Can olanzapine be implicated in causing serotonin syndrome? ( Haslett, CD; Kumar, S, 2002) |
| " This resistant case of lethal catatonia responded selectively to high-dose olanzapine treatment." | 3.71 | Lethal catatonia responding to high-dose olanzapine therapy. ( Cassidy, EM; Finucane, J; O'Brien, M; O'Keane, V; Osman, MF, 2001) |
| "To report a case of neuroleptic malignant syndrome (NMS) associated with the use of olanzapine." | 3.70 | Neuroleptic malignant syndrome associated with olanzapine. ( Billington, CJ; Ercan-Fang, N; Filice, GA; McDougall, BC, 1998) |
| "Olanzapine may be a useful alternative or adjunctive treatment for patients with bipolar disorder." | 3.70 | Clinical predictors of acute response with olanzapine in psychotic mood disorders. ( Berman, A; Greaney, JJ; Madrid, A; Narendran, R; Pike, S; Tohen, M; Zarate, CA, 1998) |
| "All charts of patients meeting DSM-IV criteria for bipolar disorder or unipolar major depressive disorder treated with olanzapine in a private psychiatric practice were reviewed and clinical response was assessed retrospectively using the Clinical Global Impression Scale for Improvement (CGI-I)." | 3.70 | Does olanzapine have antidepressant properties? A retrospective preliminary study. ( Cherry, EL; Ghaemi, SN; Goodwin, FK; Katzow, JA, 2000) |
| "The responses of seven consecutive adolescents (ages 12-17) with DSM-IV bipolar disorder, manic episode, treated with olanzapine were evaluated." | 3.70 | Olanzapine in the treatment of adolescent acute mania: a report of seven cases. ( Foster, KD; Keck, PE; McElroy, SL; Sorter, MT; Soutullo, CA, 1999) |
| "We report on three cases of acutely manic prepubertal children diagnosed with bipolar disorder who were treated with olanzapine in addition to their existing mood stabilizer regimens." | 3.70 | Mood stabilizer augmentation with olanzapine in acutely manic children. ( Chang, KD; Ketter, TA, 2000) |
| "Olanzapine treated subjects achieved statistically significantly greater rates of clinical response, euthymia and remission than those assigned to placebo, 55% versus 29." | 2.71 | Rates of response, euthymia and remission in two placebo-controlled olanzapine trials for bipolar mania. ( Baker, RW; Chengappa, KN; Gershon, S; Kupfer, DJ; Shao, L; Tohen, M; Yatham, LN, 2003) |
| "The design consisted of 2 successive, 6-week, double-blind periods and compared flexible dosing of olanzapine (5-20 mg/d, n = 234) with haloperidol (3-15 mg/d, n = 219)." | 2.71 | A 12-week, double-blind comparison of olanzapine vs haloperidol in the treatment of acute mania. ( Azorin, JM; Baker, RW; Breier, A; Emsley, RA; Evans, AR; Goldberg, JF; Gonzalez-Pinto Arrillaga, AM; Hardy-Bayle, MC; Lawson, WB; Namjoshi, MA; Risser, RC; Tohen, M; Vieta, E; Zhang, F, 2003) |
| " These findings suggest that intramuscular olanzapine is a safe and effective treatment for reducing acute agitation in patients with bipolar mania." | 2.70 | A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania. ( Breier, A; David, S; Janicak, P; Koch, M; Meehan, K; Rizk, R; Small, J; Tohen, M; Tran, P; Walker, D; Zhang, F, 2001) |
| "Patients with schizoaffective disorder bipolar type, characterized as currently manic, mixed, depressed, or euthymic, were assessed weekly for 6 weeks during treatment with either olanzapine or haloperidol." | 2.70 | Olanzapine versus haloperidol in schizoaffective disorder, bipolar type. ( Breier, A; Feldman, PD; Keck, PE; Risser, RC; Tohen, M; Tran, PV; Zhang, F, 2001) |
| "The olanzapine treatment group had significantly greater mean improvement of mania ratings and a significantly greater proportion of patients achieving protocol-defined remission, compared with the divalproex treatment group." | 2.70 | Olanzapine versus divalproex in the treatment of acute mania. ( Altshuler, LL; Baker, RW; Breier, A; Gilmore, JA; Ketter, TA; Milton, DR; Risser, R; Suppes, T; Tohen, M; Tollefson, GA; Zarate, CA, 2002) |
| "Olanzapine has been shown to be superior to placebo for the treatment of mania." | 2.70 | The impact of response to previous mood stabilizer therapy on response to olanzapine versus placebo for acute mania. ( Baker, RW; Goldberg, JF; Milton, DR; Schuh, LM; Stauffer, VL; Tohen, M, 2002) |
| "Classic neuroleptic malignant syndrome (NMS) was diagnosed." | 2.42 | Neuroleptic malignant syndrome in an adolescent receiving olanzapine-lithium combination therapy. ( Berry, N; Gupta, SK; Pradhan, S; Sagar, R, 2003) |
| "Olanzapine is an effective treatment for mania and may be more efficacious than divalproex, though leads to more weight gain." | 2.42 | Olanzapine alone or in combination for acute mania. ( Geddes, JR; Gijsman, HJ; Goodwin, GM; Keck, P; Rendell, JM, 2003) |
| " Their adverse effects, which include extrapyramidal side effects, tardive dyskinesia, weight gain, sedation, and sexual dysfunction, often lead to non-compliance; their use may have a negative impact on the overall course of illness; and they may not be as effective as lithium in treating the core manic symptoms over the long term." | 2.41 | Antipsychotic drug side effect issues in bipolar manic patients. ( Zarate, CA, 2000) |
| "Olanzapine has a multireceptorial binding profile including a greater affinity for serotonin 5-HT(2A) than for dopamine D(2) receptors." | 2.41 | Olanzapine: a review of its use in the treatment of bipolar I disorder. ( Bhana, N; Perry, CM, 2001) |
| " Among the group receiving novel antipsychotics, dosage was not related to satisfaction or burden of adverse effects." | 1.31 | Short report: comparison of patient satisfaction and burden of adverse effects with novel and conventional neuroleptics: a naturalistic study. ( Bromet, EJ; Davidson, M; Rabinowitz, J, 2001) |
| "Psychopharmacology research aims to expand the therapeutic ratio between efficacy, on the one hand, and adverse events and safety, on the other." | 1.31 | Psychotropic drugs and adverse events in the treatment of bipolar disorders revisited. ( McIntyre, RS, 2002) |
| "Olanzapine is a relatively new antipsychotic agent which appears to be effective in the treatment of both the positive and negative symptoms of schizophrenia." | 1.30 | Olanzapine-induced mania. ( Brannon, GE; McBride, WA; Reeves, RR, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 33 (25.58) | 18.2507 |
| 2000's | 95 (73.64) | 29.6817 |
| 2010's | 1 (0.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gibbons, AS | 1 |
| Jeon, WJ | 1 |
| Scarr, E | 1 |
| Dean, B | 1 |
| Paquet, V | 1 |
| Strul, J | 1 |
| Servais, L | 1 |
| Pelc, I | 1 |
| Fossion, P | 1 |
| Shi, L | 1 |
| Namjoshi, MA | 4 |
| Zhang, F | 5 |
| Gandhi, G | 1 |
| Edgell, ET | 1 |
| Tohen, M | 25 |
| Breier, A | 12 |
| Haro, JM | 1 |
| Haslett, CD | 1 |
| Kumar, S | 1 |
| Gonzalez-Pinto, A | 2 |
| Lalaguna, B | 2 |
| Pérez-Heredia, JL | 1 |
| Fernandez-Corres, B | 1 |
| Gutierrez, M | 2 |
| Micó, JA | 1 |
| Malhi, GS | 1 |
| Berk, M | 2 |
| Janenawasin, S | 1 |
| Wang, PW | 1 |
| Lembke, A | 1 |
| Schumacher, M | 1 |
| Das, B | 1 |
| Santosa, CM | 1 |
| Mongkolcheep, J | 1 |
| Ketter, TA | 7 |
| Leung, M | 1 |
| Wrixon, K | 1 |
| Remick, RA | 1 |
| Arnone, D | 1 |
| Hansen, L | 1 |
| Kerr, JS | 1 |
| Baker, RW | 10 |
| Milton, DR | 3 |
| Stauffer, VL | 3 |
| Gelenberg, A | 1 |
| Sanger, TM | 5 |
| Vieta, E | 6 |
| Dunner, DL | 1 |
| Bowden, CL | 3 |
| Calabrese, JR | 2 |
| Feldman, PD | 4 |
| Jacobs, TG | 4 |
| Zajecka, JM | 2 |
| Weisler, R | 1 |
| Sachs, G | 3 |
| Swann, AC | 2 |
| Wozniak, P | 2 |
| Sommerville, KW | 3 |
| Goveas, JS | 1 |
| Hermida, A | 1 |
| Kucerová, H | 1 |
| Berry, N | 1 |
| Pradhan, S | 1 |
| Sagar, R | 1 |
| Gupta, SK | 1 |
| Manning, JS | 1 |
| Fawcett, J | 1 |
| Risser, RC | 6 |
| Schuh, LM | 3 |
| Brown, E | 2 |
| Shao, L | 2 |
| Tollefson, GD | 5 |
| Miller, TJ | 1 |
| Zipursky, RB | 1 |
| Perkins, D | 1 |
| Addington, J | 1 |
| Woods, SW | 1 |
| Hawkins, KA | 1 |
| Hoffman, R | 1 |
| Preda, A | 1 |
| Epstein, I | 1 |
| Addington, D | 1 |
| Lindborg, S | 1 |
| Marquez, E | 1 |
| McGlashan, TH | 1 |
| Chengappa, KN | 4 |
| Yatham, LN | 5 |
| Gershon, S | 1 |
| Kupfer, DJ | 3 |
| Frye, MA | 2 |
| Gitlin, MJ | 1 |
| Altshuler, LL | 3 |
| Shelton, RC | 2 |
| Keck, PE | 6 |
| Maguire, GA | 1 |
| Phillips, G | 1 |
| Gupta, S | 1 |
| Baldessarini, RJ | 2 |
| Dennehy, EB | 1 |
| Doyle, K | 1 |
| Suppes, T | 5 |
| Revicki, DA | 1 |
| Paramore, LC | 1 |
| Grof, P | 1 |
| Kolpe, M | 1 |
| Ravasia, S | 1 |
| Gnanadesikan, M | 1 |
| Freeman, MP | 1 |
| Gelenberg, AJ | 1 |
| Battaglia, J | 1 |
| Lindborg, SR | 1 |
| Alaka, K | 1 |
| Meehan, K | 2 |
| Wright, P | 1 |
| Zarate, CA | 7 |
| Frye, M | 2 |
| Altshuler, L | 2 |
| Zajecka, J | 1 |
| Iwazaki, H | 1 |
| Rendell, JM | 1 |
| Gijsman, HJ | 1 |
| Keck, P | 1 |
| Goodwin, GM | 1 |
| Geddes, JR | 1 |
| McIntyre, RS | 2 |
| Mancini, DA | 1 |
| Basile, VS | 1 |
| Srinivasan, J | 1 |
| Kennedy, SH | 1 |
| Hennen, J | 1 |
| Wilson, M | 1 |
| Calabrese, J | 2 |
| Chengappa, R | 1 |
| McElroy, SL | 5 |
| Welge, JA | 1 |
| Sattar, SP | 1 |
| Grant, K | 1 |
| Bhatia, S | 1 |
| Petty, F | 2 |
| Christensen, RC | 1 |
| Hirschfeld, RM | 1 |
| Baker, JD | 1 |
| Tracy, K | 1 |
| Tavakoli, SA | 1 |
| Arguisola, MS | 1 |
| Grunze, H | 1 |
| Dittmann, S | 1 |
| Bowden, C | 1 |
| Mitchell, PB | 1 |
| Centorrino, F | 2 |
| Risser, R | 4 |
| Evans, AR | 2 |
| Beymer, K | 1 |
| Dube, S | 1 |
| Hoeh, N | 1 |
| Gyulai, L | 1 |
| Weintraub, D | 1 |
| Streim, J | 1 |
| Goldberg, JF | 2 |
| Gonzalez-Pinto Arrillaga, AM | 1 |
| Azorin, JM | 1 |
| Hardy-Bayle, MC | 1 |
| Lawson, WB | 1 |
| Emsley, RA | 1 |
| Ravindran, AV | 1 |
| Jones, BW | 1 |
| al-Zaid, K | 1 |
| Lapierre, YD | 1 |
| London, JA | 1 |
| Narendran, R | 2 |
| Greaney, JJ | 1 |
| Berman, A | 1 |
| Pike, S | 1 |
| Madrid, A | 1 |
| Winsberg, ME | 1 |
| DeGolia, SG | 1 |
| Dunai, M | 1 |
| Tate, DL | 1 |
| Strong, CM | 1 |
| Weisler, RH | 1 |
| Ahearn, EP | 1 |
| Davidson, JR | 1 |
| Wallace, CD | 1 |
| Denicoff, K | 2 |
| Dunn, RT | 1 |
| Kimbrell, TA | 1 |
| Corá-Locatelli, G | 1 |
| Post, RM | 2 |
| Nolen, W | 1 |
| Kupka, R | 1 |
| Leverich, GS | 1 |
| Kmetz, GF | 1 |
| Lindenmayer, JP | 1 |
| Klebanov, R | 1 |
| Rosen, EH | 1 |
| Reeves, RR | 1 |
| McBride, WA | 1 |
| Brannon, GE | 1 |
| Filice, GA | 1 |
| McDougall, BC | 1 |
| Ercan-Fang, N | 1 |
| Billington, CJ | 1 |
| Pozo, P | 1 |
| Alcántara, AG | 1 |
| John, V | 1 |
| Rapp, M | 1 |
| Pies, R | 1 |
| Sharma, V | 1 |
| Pistor, L | 1 |
| Rothschild, AJ | 1 |
| Bates, KS | 1 |
| Boehringer, KL | 1 |
| Syed, A | 1 |
| Grundy, S | 1 |
| Kane, JM | 1 |
| Heimann, SW | 1 |
| Daniel, DG | 1 |
| Wang, R | 1 |
| Grundy, SL | 3 |
| Greaney, MG | 2 |
| David, SR | 1 |
| Toma, V | 3 |
| Fitz-Gerald, MJ | 1 |
| Pinkofsky, HB | 1 |
| Brannon, G | 1 |
| Dandridge, E | 1 |
| Calhoun, A | 1 |
| Soutullo, CA | 1 |
| Sorter, MT | 1 |
| Foster, KD | 1 |
| Zullino, D | 1 |
| Baumann, P | 1 |
| Benazzi, F | 2 |
| Dunayevich, E | 1 |
| Strakowski, SM | 1 |
| Gheorghiu, S | 1 |
| Knobler, HY | 1 |
| Drumer, D | 1 |
| Ichim, L | 1 |
| Brook, S | 1 |
| Simon, AE | 2 |
| Aubry, JM | 2 |
| Malky, L | 1 |
| Bertschy, G | 2 |
| Ananth, J | 1 |
| Khan, M | 1 |
| Farver, D | 1 |
| Chang, KD | 1 |
| Ohaeri, JU | 1 |
| Shad, U | 1 |
| Preskorn, SH | 1 |
| Izgur, Z | 1 |
| Khouzam, HR | 1 |
| El-Gabalawi, F | 1 |
| Vernon, LT | 1 |
| Fuller, MA | 1 |
| Hattab, H | 1 |
| Varnes, KM | 1 |
| Banov, MC | 1 |
| Janicak, PG | 1 |
| Sanger, T | 1 |
| Francis, J | 1 |
| Solhkhah, R | 1 |
| Finkel, J | 1 |
| Hird, S | 1 |
| Guille, C | 1 |
| Sachs, GS | 2 |
| Ghaemi, SN | 3 |
| Esel, E | 1 |
| Turan, MT | 1 |
| Sofuoglu, S | 1 |
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| Janowsky, DS | 1 |
| Price, PL | 1 |
| Nemeroff, CB | 1 |
| Goodnick, PJ | 2 |
| Levine, J | 1 |
| Jacobs, T | 2 |
| Thase, ME | 1 |
| Cherry, EL | 1 |
| Katzow, JA | 1 |
| Goodwin, FK | 1 |
| Roefaro, J | 1 |
| Mukherjee, SM | 1 |
| Lykouras, L | 1 |
| Gournellis, R | 1 |
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| Umbricht, D | 1 |
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| Walker, D | 1 |
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| Young, CM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Orally-Disintegrating vs. Regular Olanzapine Tablets: Effects on Weight and GI Hormones[NCT00384332] | Phase 4 | 20 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| An Open Label Trial of Ziprasidone as an Adjuvant for Clozapine- or Olanzapine-Associated Diabetes Mellitus or Impaired Fasting Glucose in Chronic Schizophrenia[NCT00351000] | Phase 4 | 24 participants (Actual) | Interventional | 2005-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Montgomery Asberg Depression Rating Scale (MADRS) total score. Construct: Depression severity. Scores below represent mean change scores, endpoint minus baseline. Minimum total score: 0 (no depression). Maximum total score: 60 (severe depression). Lower (more negative) scores indicate a better outcome. There are no subscales. (NCT00384332)
Timeframe: 10 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Arm 1 | -15.5 |
| Arm 2 | -15.5 |
Change in weight from baseline to endpoint in kilograms. Reported as weight in Kilograms at Baseline, Weeks 1, 4, 6, and 8 (NCT00384332)
Timeframe: 10 weeks
| Intervention | kilograms (Mean) | ||||
|---|---|---|---|---|---|
| Baseline | Week 1 | Week 4 | Week 6 | Week 8 | |
| Arm 1- ODT | 76.0 | 77.4 | 77.8 | 78.9 | 79.1 |
| Arm 2- SOT | 76.1 | 77.6 | 78.3 | 79.4 | 80.1 |
Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting glucose levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6
| Intervention | mg/dL (Mean) |
|---|---|
| Clozapine Treatment With Adjunctive Ziprasidone | 5 |
| Olanzapine Treatment With Adjunctive Ziprasidone | -4.5 |
Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting insulin levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6
| Intervention | microIU/L (Mean) |
|---|---|
| Clozapine Treatment With Adjunctive Ziprasidone | 1 |
| Olanzapine Treatment With Adjunctive Ziprasidone | -0.9 |
33 reviews available for pirenzepine and Bipolar Disorder
| Article | Year |
|---|---|
Pharmacotherapy of bipolar disorder: the role of atypical antipsychotics and experimental strategies.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Clozapine; Dibenz | 2002 |
Neuroleptic malignant syndrome in an adolescent receiving olanzapine-lithium combination therapy.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnosis, Differential; Drug T | 2003 |
Difficult-to-treat depressions: a primary care perspective.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Com | 2003 |
Treating acute mania.
Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Li | 2003 |
Treating bipolar depression.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; | 2003 |
Long-term therapy of bipolar illness.
Topics: Affect; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Co | 2003 |
Optimal dosing of medications (in bipolar disorder).
Topics: Acute Disease; Affect; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Ch | 2003 |
Safety in treating bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Diabetes Melli | 2003 |
Selecting effective long-term treatment for bipolar patients: monotherapy and combinations.
Topics: Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Comorbidity; Drug Therapy, | 2003 |
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar | 2003 |
The combination of olanzapine and fluoxetine in mood disorders.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Com | 2003 |
[Manic phase (manic episode)].
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental | 2003 |
Olanzapine alone or in combination for acute mania.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination; Humans; Olanzapi | 2003 |
The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dia | 2003 |
[Treatment of acute bipolar disorder. Intriguing balancing act between mania and depression].
Topics: Acute Disease; Algorithms; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiaze | 2003 |
Pharmacologic management of psychosis in the elderly: a critical review.
Topics: Aged; Alzheimer Disease; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder; Drug Adm | 2003 |
Acute and maintenance treatment of bipolar mania: the role of atypical antipsychotics.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination | 2003 |
Antipsychotic agents and bipolar disorder.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Cl | 1998 |
Clozapine in bipolar disorder: treatment implications for other atypical antipsychotics.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cl | 1998 |
Atypical antipsychotics for treatment of depression in schizophrenia and affective disorders. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Comorb | 1998 |
Treatment of special populations with the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Adult; Age Factors; Aged; Algorithms; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clini | 1998 |
Management of acute mania.
Topics: Acute Disease; Algorithms; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; | 1999 |
Tardive dyskinesia in affective disorders.
Topics: Adult; Affective Disorders, Psychotic; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipol | 1999 |
Rapid resolution of antipsychotic-induced tardive dyskinesia with olanzapine.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Chronic Disease; Dysk | 2000 |
Antipsychotic drug side effect issues in bipolar manic patients.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Dibenz | 2000 |
Possible induction of mania and hypomania by olanzapine or risperidone: a critical review of reported cases.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dose-Response Relationship, Drug; Fe | 2000 |
New treatments of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clinical Tri | 1999 |
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamaz | 2000 |
New treatments for bipolar disorder: the role of atypical neuroleptic agents.
Topics: Acute Disease; Algorithms; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazep | 2000 |
Use of olanzapine in non-psychotic psychiatric disorders.
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive Disorder; Humans; Ol | 2001 |
Olanzapine: a review of its use in the treatment of bipolar I disorder.
Topics: Animals; Benzodiazepines; Bipolar Disorder; Humans; Olanzapine; Pirenzepine; Selective Serotonin Reu | 2001 |
Use of atypical antipsychotics in mood disorders.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Depres | 2001 |
The role of novel antipsychotics in bipolar disorders.
Topics: Acute Disease; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Haloperidol; Humans; Lithium; Ol | 2002 |
34 trials available for pirenzepine and Bipolar Disorder
| Article | Year |
|---|---|
Olanzapine versus haloperidol in the treatment of acute mania: clinical outcomes, health-related quality of life and work status.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; | 2002 |
Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapine.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Che | 2002 |
Olanzapine in diverse syndromal and subsyndromal exacerbations of bipolar disorders.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Male; Olanzapine; Pi | 2002 |
Placebo-controlled trials do not find association of olanzapine with exacerbation of bipolar mania.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Disease Progression; Double-Blind Me | 2003 |
Olanzapine in the acute treatment of bipolar I disorder with a history of rapid cycling.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Male; Middle Aged; O | 2003 |
A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Metho | 2002 |
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Comorbidity; Depressive | 2003 |
Rates of response, euthymia and remission in two placebo-controlled olanzapine trials for bipolar mania.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dose-Response Relationship, Drug; Fe | 2003 |
The efficacy of olanzapine monotherapy for acute hypomania or mania in an outpatient setting.
Topics: Administration, Oral; Adult; Affect; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female | 2003 |
Divalproex sodium versus olanzapine in the treatment of acute mania in bipolar disorder: health-related quality of life and medical cost outcomes.
Topics: Acute Disease; Adult; Ambulatory Care; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipol | 2003 |
Calming versus sedative effects of intramuscular olanzapine in agitated patients.
Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dementia; Doubl | 2003 |
Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study.
Topics: Acute Disease; Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Doub | 2003 |
Antipsychotic-induced weight gain: bipolar disorder and leptin.
Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body M | 2003 |
Olanzapine versus placebo in acute mania: treatment responses in subgroups.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dou | 2003 |
Potential use of olanzapine in treatment of substance dependence disorders.
Topics: Alcoholism; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cocaine-Related Disorders; Huma | 2003 |
The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dia | 2003 |
Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.
Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Bipolar Diso | 2003 |
A 12-week, double-blind comparison of olanzapine vs haloperidol in the treatment of acute mania.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dose-Response Relatio | 2003 |
Olanzapine in treatment-resistant bipolar disorder.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Olanzapine; Pirenzepine; Prospectiv | 1998 |
Olanzapine versus placebo in the treatment of acute mania. Olanzapine HGEH Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepin | 1999 |
Olanzapine compared to lithium in mania: a double-blind randomized controlled trial.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Metho | 1999 |
Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dou | 2000 |
A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Bipolar Disorder; Body Weight; | 2000 |
Response to placebo among bipolar I disorder patients experiencing their first manic episode.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; | 2000 |
Long-term olanzapine therapy in the treatment of bipolar I disorder: an open-label continuation phase study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive Disorder; Double-Blind Me | 2001 |
A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania.
Topics: Adult; Affect; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Choline | 2001 |
Olanzapine therapy in treatment-resistant psychotic mood disorders: a long-term follow-up study.
Topics: Adult; Affective Disorders, Psychotic; Aged; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; | 2001 |
Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Disorders of Excessive Somnolence; D | 2001 |
A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder.
Topics: Abdominal Pain; Adolescent; Antipsychotic Agents; Appetite; Benzodiazepines; Bipolar Disorder; Brief | 2001 |
Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy.
Topics: Acute Disease; Adult; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Drug | 2002 |
Olanzapine versus haloperidol in schizoaffective disorder, bipolar type.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind M | 2001 |
Olanzapine versus divalproex in the treatment of acute mania.
Topics: Acute Disease; Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Doub | 2002 |
The impact of response to previous mood stabilizer therapy on response to olanzapine versus placebo for acute mania.
Topics: Adult; Benzodiazepines; Bipolar Disorder; Female; Humans; Male; Olanzapine; Pirenzepine; Psychiatric | 2002 |
Economic, clinical, and quality-of-life outcomes associated with olanzapine treatment in mania. Results from a randomized controlled trial.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cost-Benefit Analysis; Costs and Cos | 2002 |
63 other studies available for pirenzepine and Bipolar Disorder
| Article | Year |
|---|---|
Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Depressive Diso | 2016 |
Sleep-related eating disorder induced by olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination; Feeding and Eati | 2002 |
Can olanzapine be implicated in causing serotonin syndrome?
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Citalopram; Female; Humans; Lithium Chlorid | 2002 |
Olanzapine-induced hair loss.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Delusions; Female; Hair Diseases; Hu | 2002 |
Acute dystonic reaction in an elderly patient with mood disorder after titration of paroxetine: possible mechanisms and implications for clinical care.
Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodi | 2002 |
Olanzapine induced "typical" neuroleptic malignant syndrome.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dopamine; Humans; Male; Neuroleptic M | 2003 |
Olanzapine and improvement of tardive dyskinesia.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Hum | 2002 |
Acute dysphoric mania: treatment response to olanzapine versus placebo.
Topics: Acute Disease; Affect; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Olanzapine; | 2003 |
Improving identification of treatment effectiveness in bipolar disorders.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Fluoxetine; Human | 2003 |
Assessment of treatment response in mania: commentary and new findings.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental | 2003 |
Effect of olanzapine on the liver transaminases.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Liver; Olanzapine; P | 2003 |
Olanzapine-associated bilateral pedal edema.
Topics: Adult; Ankle; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Edema; Female; Foot Diseases; | 2003 |
Diabetic ketoacidosis in a patient treated with olanzapine, valproic acid, and venlafaxine.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepi | 2003 |
[Fast control of manic or mixed episodes. Atypical neuroleptics for bipolar patients].
Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical T | 2003 |
[Long-term therapy with intuition].
Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical T | 2003 |
Divalproex versus olanzapine in mania.
Topics: Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bias; Bipolar Disorder; Clinical Trials as T | 2003 |
Effective treatment of mania with olanzapine: 2 case reports.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Male; Middle Aged; O | 1997 |
Mania associated with olanzapine.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Male; Olanzapine; Piren | 1998 |
Clinical predictors of acute response with olanzapine in psychotic mood disorders.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Age Factors; Antipsychotic Agents; Benzodiazepine | 1998 |
Rapid efficacy of olanzapine augmentation in nonpsychotic bipolar mixed states.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination; Female; H | 1998 |
Adjunctive use of olanzapine in mood disorders: five case reports.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Delusions; Depressive Disorder, Majo | 1997 |
Olanzapine-induced manic-like syndrome.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Administration Schedule; Hospit | 1998 |
Olanzapine and negative symptoms.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Male; Middle Aged; Olanzapine; Pire | 1998 |
Olanzapine-induced mania.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Male; Olanzapine; Pirenzepin | 1998 |
Neuroleptic malignant syndrome associated with olanzapine.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Male; Neuroleptic Malignant S | 1998 |
Mania-like syndrome in a patient with chronic schizophrenia during olanzapine treatment.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Middle Aged; Olanzapine; Pi | 1998 |
Aggression, agitation, and mania with olanzapine.
Topics: Adult; Aggression; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; | 1998 |
Treatment of bipolar mixed state with olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination; Female; H | 1999 |
Olanzapine response in psychotic depression.
Topics: Adult; Affective Disorders, Psychotic; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depr | 1999 |
High-dose olanzapine in an adolescent.
Topics: Adolescent; Adolescent Psychiatry; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dose-Res | 1999 |
Olanzapine-induced mania.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Male; Olanzapine; Pirenzepin | 1999 |
Olanzapine in the treatment of adolescent acute mania: a report of seven cases.
Topics: Acute Disease; Adolescent; Benzodiazepines; Bipolar Disorder; Child; Female; Humans; Male; Olanzapin | 1999 |
Olanzapine for mixed episodes of bipolar disorder.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Middle Aged; Olanzapine; Pi | 1999 |
Olanzapine-induced psychotic mania in bipolar schizoaffective disorder.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Middle Aged; Olanzapine; Pi | 1999 |
Olanzapine-induced tardive dystonia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dyskinesia, Drug-Induced; Dystonia; | 1999 |
Recurrence of neuroleptic malignant syndrome with olanzapine treatment.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorprothixene; Clopenthixol; Female | 1999 |
Hypomania-like syndrome induced by olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Olanzapine; Pirenzep | 1999 |
Is olanzapine a mood stabilizer?
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Middle Aged; Olanzapine; Pi | 1999 |
Olanzapine-induced psychotic mania in bipolar schizo-affective disorder.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Middle Aged; Olanzapine; Pi | 1999 |
Mood stabilizer augmentation with olanzapine in acutely manic children.
Topics: Antimanic Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Benzodiazepin | 2000 |
Naturalistic study of olanzapine in treatment-resistant schizophrenia and acute mania, depression and obsessional disorder.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive Disorde | 2000 |
Failure to consider drug-drug interactions as a likely cause of behavioral deterioration in a patient with bipolar disorder.
Topics: Adult; Antipsychotic Agents; Behavior; Benzodiazepines; Benztropine; Bipolar Disorder; Drug Interact | 2000 |
Treatment of bipolar I disorder in an adolescent with olanzapine.
Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Male; | 2000 |
Olanzapine-induced urinary incontinence: treatment with ephedrine.
Topics: Benzodiazepines; Bipolar Disorder; Ephedrine; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Ur | 2000 |
Possible risperidone-induced visual hallucinations.
Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnosis, Du | 2000 |
Improvement of tardive dyskinesia in a bipolar patient with olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Humans; M | 2000 |
Olanzapine to treat the acute mania of bipolar disorder.
Topics: Acute Disease; Affect; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Bipolar Disord | 2000 |
Introduction: a new era in the pharmacotherapy of psychotic disorders.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Administration Schedule | 2001 |
Summary from the 153rd meeting of the American Psychiatric Association. 13-18 May 2000, Chicago, Illinois, USA.
Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Citalopram; Depressi | 2000 |
Does olanzapine have antidepressant properties? A retrospective preliminary study.
Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depress | 2000 |
Olanzapine-lnduced hyperglycemic nonketonic coma.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Blood Glucose; Humans; Hyperglycemic Hypero | 2001 |
Manic symptoms induced by olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Female; Humans; Olanzapine; Pirenzep | 2001 |
Cognitive behavior therapy for weight gain.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Cognitive Behavioral Ther | 2001 |
Use of olanzapine in dysphoric mania.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Comb | 2001 |
Lethal catatonia responding to high-dose olanzapine therapy.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Catatonia; Electroconvulsive Therapy | 2001 |
A correction.
Topics: Acute Disease; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Double-Blind Method; Hum | 2002 |
Comparative efficacy of typical and atypical antipsychotics as add-on therapy to mood stabilizers in the treatment of acute mania.
Topics: Acute Disease; Adult; Antimanic Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepine | 2001 |
Short report: comparison of patient satisfaction and burden of adverse effects with novel and conventional neuroleptics: a naturalistic study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder, Majo | 2001 |
Olanzapine in acute bipolar mania.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Humans; | 2002 |
Psychotropic drugs and adverse events in the treatment of bipolar disorders revisited.
Topics: Anticonvulsants; Benzodiazepines; Bipolar Disorder; Dibenzothiazepines; Female; Fructose; Humans; La | 2002 |
Olanzapine-induced mania in bipolar disorders.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Male; Middle Aged; Olanzapine; Pire | 2002 |
Olanzapine-associated type 2 diabetes mellitus.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body Weight; Diabetes Mellitus, Type | 2002 |
Olanzapine-induced obsessive-compulsive symptoms in a patient with bipolar II disorder.
Topics: Adult; Benzodiazepines; Bipolar Disorder; Female; Humans; Obsessive-Compulsive Disorder; Olanzapine; | 2002 |