Page last updated: 2024-11-02

pirenzepine and Aura

pirenzepine has been researched along with Aura in 2 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Research Excerpts

ExcerptRelevanceReference
" Here we investigated the effect of the mAChR agonist carbachol (CCh) and various mAChR antagonists in human cortical slices (from tissue removed during neurosurgical treatment of epilepsy) by intracellular and extracellular recordings."3.78Muscarinic acetylcholine receptor-mediated effects in slices from human epileptogenic cortex. ( Dehnicke, C; Deisz, RA; Gigout, S; Horn, P; Lehmann, TN; Wierschke, S, 2012)
", ip) indicate that the liver is the primary site of biotransformation of the compound, suggesting that both 22a and its metabolite(s) are active, compensating probably low bioavailability of the parent molecule."1.43Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. ( Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Waszkielewicz, AM1
Gunia-Krzyżak, A1
Powroźnik, B1
Słoczyńska, K1
Pękala, E1
Walczak, M1
Bednarski, M1
Żesławska, E1
Nitek, W1
Marona, H1
Gigout, S1
Wierschke, S1
Lehmann, TN1
Horn, P1
Dehnicke, C1
Deisz, RA1

Other Studies

2 other studies available for pirenzepine and Aura

ArticleYear
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
    Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8

    Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Dru

2016
Muscarinic acetylcholine receptor-mediated effects in slices from human epileptogenic cortex.
    Neuroscience, 2012, Oct-25, Volume: 223

    Topics: Action Potentials; Adult; Biophysics; Carbachol; Cerebral Cortex; Cholinergic Agonists; Drug Combina

2012