Page last updated: 2024-11-02

pirenzepine and Astrocytoma

pirenzepine has been researched along with Astrocytoma in 4 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stephan, CC1
Sastry, BV1
Matute, C1
Arellano, RO1
Conde-Guerri, B1
Miledi, R1
Brown, JH1
Goldstein, D1
Masters, SB1
Kunysz, EA1
Michel, AD1
Whiting, RL1
Woods, K1

Other Studies

4 other studies available for pirenzepine and Astrocytoma

ArticleYear
Characterization of the subtype of muscarinic receptor coupled to the stimulation of phosphoinositide hydrolysis in 132-1N1 human astrocytoma cells.
    Cellular and molecular biology (Noisy-le-Grand, France), 1992, Volume: 38, Issue:7

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Astrocytoma; Atropine; Carbach

1992
mRNA coding for neurotransmitter receptors in a human astrocytoma.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Apr-15, Volume: 89, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Animals; Astrocytoma; Brain

1992
The putative M1 muscarinic receptor does not regulate phosphoinositide hydrolysis. Studies with pirenzepine and McN-A343 in chick heart and astrocytoma cells.
    Molecular pharmacology, 1985, Volume: 27, Issue:5

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Astrocytoma; Benzodia

1985
The human astrocytoma cell line 1321 N1 contains M2-glandular type muscarinic receptors linked to phosphoinositide turnover.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Animals; Astrocytoma; Binding, Competitive; Humans; Inositol Phosphates; Male; N-Methylscopolamine;

1989