pirenzepine has been researched along with Arrhythmias, Cardiac in 7 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results of these analyses suggest that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute to QTc prolongation resulting in potentially fatal ventricular arrhythmias." | 9.09 | Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis. ( Beasley, CM; Berg, PH; Czekalla, J; Dellva, MA; Grundy, S, 2001) |
| "Results of these analyses suggest that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute to QTc prolongation resulting in potentially fatal ventricular arrhythmias." | 5.09 | Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis. ( Beasley, CM; Berg, PH; Czekalla, J; Dellva, MA; Grundy, S, 2001) |
| " The present article reviews important differences among antipsychotic drugs in the potential for, and occurrence of, serious adverse cardiac outcomes and suggests that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute significantly to a QTc prolongation that could result in potentially fatal ventricular arrhythmias." | 4.81 | Cardiac safety parameters of olanzapine: comparison with other atypical and typical antipsychotics. ( Beasley, CM; Czekalla, J; Kollack-Walker, S, 2001) |
| " This is because of their efficacy in the treatment of several psychiatric disorders, ease of administration, and absence of the well-known extrapyramidal adverse effects long-attributed to the standard dopamine blocking anti-psychotic medications." | 2.42 | Atypical psychotropic medications and their adverse effects: a review for the African-American primary care physician. ( Bailey, RK, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bailey, RK | 1 |
| Cadario, B | 1 |
| Czekalla, J | 2 |
| Kollack-Walker, S | 1 |
| Beasley, CM | 2 |
| Dellva, MA | 1 |
| Berg, PH | 1 |
| Grundy, S | 1 |
| Wilton, LV | 1 |
| Heeley, EL | 1 |
| Pickering, RM | 1 |
| Shakir, SA | 1 |
| Cohen, H | 1 |
| Loewenthal, U | 1 |
| Matar, M | 1 |
| Kotler, M | 1 |
2 reviews available for pirenzepine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Atypical psychotropic medications and their adverse effects: a review for the African-American primary care physician.
Topics: Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Black or African American; | 2003 |
Cardiac safety parameters of olanzapine: comparison with other atypical and typical antipsychotics.
Topics: Acute Disease; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Death, Sudden; Female; H | 2001 |
1 trial available for pirenzepine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis.
Topics: Acute Disease; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antipsychotic Agent | 2001 |
4 other studies available for pirenzepine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Otenzepad. AFDX 116.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Drug Interactions; Drugs, Investigation | 1999 |
Olanzapine (Zyprexa): suspected serious reactions.
Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines | 2000 |
Comparative study of mortality rates and cardiac dysrhythmias in post-marketing surveillance studies of sertindole and two other atypical antipsychotic drugs, risperidone and olanzapine.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Cohort | 2001 |
[Heart rate variability in schizophrenic patients treated with antipsychotic agents].
Topics: Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Clozapine; Female; Haloperidol; | 2001 |