Page last updated: 2024-11-02

pirenzepine and Amentia

pirenzepine has been researched along with Amentia in 23 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Research Excerpts

ExcerptRelevanceReference
"In a double-blind parallel study allowing dose titration over 14 days, 39 agitated persons with DSM-IV dementia who were residing in long-term care facilities were administered olanzapine (N = 20) or risperidone (N = 19) as acute treatment."9.10A double-blind comparison of olanzapine versus risperidone in the acute treatment of dementia-related behavioral disturbances in extended care facilities. ( Fontaine, CS; Hynan, LS; Koch, K; Martin-Cook, K; Svetlik, D; Weiner, MF, 2003)
"To compare the effects of risperidone and olanzapine on cognition in elderly patients with dementia and psychosis, and to compare the side effects of these drugs."9.10Comparison of risperidone with olanzapine in elderly patients with dementia and psychosis. ( Arndt, S; Ekstam-Smith, K; Ellingrod, VL; Kutscher, E; Schultz, SK; Turvey, C, 2002)
"This double-blind study investigated the efficacy and safety of rapid-acting intramuscular olanzapine in treating agitation associated with Alzheimer's disease and/or vascular dementia."9.10Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia. ( Beasley, CM; Beckett, LM; Breier, A; David, SR; Feldman, PD; Jones, B; Meehan, KM; Mintzer, JE; Nisivoccia, JR; Wang, H, 2002)
"Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine."5.30Olanzapine for psychosis in patients with Parkinson's disease with and without dementia. ( Aarsland, D; Larsen, JP; Lim, NG; Tandberg, E, 1999)
" In 3 double-blind studies, acutely agitated patients with schizophrenia (N = 311), bipolar mania (N = 201), or dementia (N = 206) were treated with intramuscular (1-3 injections/24 hrs) olanzapine (2."5.10Calming versus sedative effects of intramuscular olanzapine in agitated patients. ( Alaka, K; Battaglia, J; Lindborg, SR; Meehan, K; Wright, P, 2003)
"In a double-blind parallel study allowing dose titration over 14 days, 39 agitated persons with DSM-IV dementia who were residing in long-term care facilities were administered olanzapine (N = 20) or risperidone (N = 19) as acute treatment."5.10A double-blind comparison of olanzapine versus risperidone in the acute treatment of dementia-related behavioral disturbances in extended care facilities. ( Fontaine, CS; Hynan, LS; Koch, K; Martin-Cook, K; Svetlik, D; Weiner, MF, 2003)
"To compare the effects of risperidone and olanzapine on cognition in elderly patients with dementia and psychosis, and to compare the side effects of these drugs."5.10Comparison of risperidone with olanzapine in elderly patients with dementia and psychosis. ( Arndt, S; Ekstam-Smith, K; Ellingrod, VL; Kutscher, E; Schultz, SK; Turvey, C, 2002)
"This double-blind study investigated the efficacy and safety of rapid-acting intramuscular olanzapine in treating agitation associated with Alzheimer's disease and/or vascular dementia."5.10Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia. ( Beasley, CM; Beckett, LM; Breier, A; David, SR; Feldman, PD; Jones, B; Meehan, KM; Mintzer, JE; Nisivoccia, JR; Wang, H, 2002)
" This article will describe the potential use of the atypical antipsychotics, especially olanzapine, for affective mood disturbances in schizophrenia, psychotic depression and mania, first-break schizophrenia, comorbid schizophrenia and substance abuse disorders, dementia in the elderly and those with late-onset schizophrenia, and behavioral problems in patients with mental retardation or developmental delays."4.79Olanzapine and the new generation of antipsychotic agents: patterns of use. ( Glazer, WM, 1997)
" Dosing requirements for elderly patients tend to be much lower than those for younger adults."2.40Conventional vs. newer antipsychotics in elderly patients. ( Harris, MJ; Jeste, DV; Lacro, J; Lohr, JB; Rockwell, E, 1999)
"Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine."1.30Olanzapine for psychosis in patients with Parkinson's disease with and without dementia. ( Aarsland, D; Larsen, JP; Lim, NG; Tandberg, E, 1999)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's7 (30.43)18.2507
2000's11 (47.83)29.6817
2010's3 (13.04)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Kołaczkowski, M3
Marcinkowska, M3
Bucki, A3
Pawłowski, M3
Mitka, K1
Jaśkowska, J1
Kowalski, P1
Kazek, G2
Siwek, A3
Wasik, A2
Wesołowska, A3
Mierzejewski, P3
Bienkowski, P2
Śniecikowska, J2
Jastrzębska-Więsek, M2
Partyka, A2
Więckowski, K1
Głuch-Lutwin, M1
Gryboś, A1
Pytka, K1
Ishioh, M1
Nozu, T1
Miyagishi, S1
Igarashi, S1
Funayama, T1
Ohhira, M1
Okumura, T1
Bullock, R1
Saharan, A1
Suh, H1
Bronson, B1
Martin, R1
Motsinger, CD1
Perron, GA1
Lacy, TJ1
Battaglia, J1
Lindborg, SR1
Alaka, K1
Meehan, K1
Wright, P1
Fontaine, CS1
Hynan, LS1
Koch, K1
Martin-Cook, K1
Svetlik, D1
Weiner, MF1
Reeves, RR1
Torres, RA1
Teaktong, T1
Piggott, MA1
Mckeith, IG2
Perry, RH1
Ballard, CG1
Perry, EK1
Tsang, SW1
Lai, MK1
Kirvell, S1
Francis, PT1
Esiri, MM1
Hope, T1
Chen, CP1
Wong, PT1
Caulfield, MP1
Straughan, DW1
Cross, AJ1
Crow, T1
Birdsall, NJ1
Maeda, T1
Satoh, M1
Glazer, WM1
Finkel, SI1
Jeste, DV1
Rockwell, E1
Harris, MJ1
Lohr, JB1
Lacro, J1
Walker, Z1
Grace, J1
Overshot, R1
Satarasinghe, S1
Swan, A1
Katona, CL1
Aarsland, D1
Larsen, JP1
Lim, NG1
Tandberg, E1
Buckley, PF1
Ellingrod, VL1
Schultz, SK1
Ekstam-Smith, K1
Kutscher, E1
Turvey, C1
Arndt, S1
Meehan, KM1
Wang, H1
David, SR1
Nisivoccia, JR1
Jones, B1
Beasley, CM1
Feldman, PD1
Mintzer, JE1
Beckett, LM1
Breier, A1

Reviews

6 reviews available for pirenzepine and Amentia

ArticleYear
Atypical antipsychotics: experience and use in the elderly.
    International journal of clinical practice, 2002, Volume: 56, Issue:7

    Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Clozapine;

2002
Olanzapine and the new generation of antipsychotic agents: patterns of use.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 10

    Topics: Antipsychotic Agents; Benzodiazepines; Child; Comorbidity; Dementia; Depressive Disorder; Developmen

1997
Managing the behavioral and psychological signs and symptoms of dementia.
    International clinical psychopharmacology, 1997, Volume: 12 Suppl 4

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dementia; Humans;

1997
Treatment of special populations with the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 12

    Topics: Adult; Age Factors; Aged; Algorithms; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clini

1998
Conventional vs. newer antipsychotics in elderly patients.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1999,Winter, Volume: 7, Issue:1

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Dementia; Dibenzothiazepines; Dose-Re

1999
Broad therapeutic uses of atypical antipsychotic medications.
    Biological psychiatry, 2001, Dec-01, Volume: 50, Issue:11

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Child; Child Development Disorders, P

2001

Trials

4 trials available for pirenzepine and Amentia

ArticleYear
Calming versus sedative effects of intramuscular olanzapine in agitated patients.
    The American journal of emergency medicine, 2003, Volume: 21, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dementia; Doubl

2003
A double-blind comparison of olanzapine versus risperidone in the acute treatment of dementia-related behavioral disturbances in extended care facilities.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:6

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Dementia; Double-Blind Method; Drug Administration Sche

2003
Comparison of risperidone with olanzapine in elderly patients with dementia and psychosis.
    Pharmacotherapy, 2002, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Cognition; Dementia; Female; Humans;

2002
Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:4

    Topics: Acute Disease; Aged; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Dementia; Double-Bl

2002

Other Studies

13 other studies available for pirenzepine and Amentia

ArticleYear
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; C

2014
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indol

2015
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.
    Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17

    Topics: Affect; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Dementia; Dopamine Agonist

2017
Activation of basal forebrain cholinergic neurons improves colonic hyperpermeability through the vagus nerve and adenosine A2B receptors in rats.
    Biochemical pharmacology, 2022, Volume: 206

    Topics: Adenosine; Animals; Basal Forebrain; Butyrates; Cholinergic Agents; Cholinergic Neurons; Dementia; O

2022
Neuroleptic malignant syndrome and low-dose olanzapine.
    The American journal of psychiatry, 2003, Volume: 160, Issue:4

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Dementia; Dose-Response Relationship

2003
Use of atypical antipsychotic drugs in patients with dementia.
    American family physician, 2003, Jun-01, Volume: 67, Issue:11

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Comorbidity; Dementia; Dibenzothiazepines; H

2003
Orally disintegrating olanzapine for the treatment of psychotic and behavioral disturbances associated with dementia.
    Southern medical journal, 2003, Volume: 96, Issue:7

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Benzodiazepi

2003
Muscarinic M2 and M4 receptors in anterior cingulate cortex: relation to neuropsychiatric symptoms in dementia with Lewy bodies.
    Behavioural brain research, 2005, Jun-20, Volume: 161, Issue:2

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Autoradiography; Binding, Competitive; Case-Control S

2005
Impaired coupling of muscarinic M1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease.
    Neurobiology of aging, 2006, Volume: 27, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Brain Chemistry; Choline O-Acetylt

2006
Cortical muscarinic receptor subtypes and Alzheimer's disease.
    Lancet (London, England), 1982, Dec-04, Volume: 2, Issue:8310

    Topics: Alzheimer Disease; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Dementia; Humans; N-Met

1982
[Experimental techniques for developing new drugs acting on dementia (3)--Experimental methods on the long-term potentiation].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1994, Volume: 14, Issue:4

    Topics: Animals; Cholinergic Agents; Dementia; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Pote

1994
Olanzapine in dementia with Lewy bodies: a clinical study.
    International journal of geriatric psychiatry, 1999, Volume: 14, Issue:6

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Cognition Disorders; Contraindicatio

1999
Olanzapine for psychosis in patients with Parkinson's disease with and without dementia.
    The Journal of neuropsychiatry and clinical neurosciences, 1999,Summer, Volume: 11, Issue:3

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Dementia; Dose-Response Relationship, Drug; Female; Hum

1999