pirenzepine has been researched along with Airway Obstruction in 4 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of a single intravenous dose of pirenzepine on ventilatory indices of 22 asthmatics was studied." | 9.07 | [Effect of pirenzepine, a selective M1 muscarinic receptor antagonist, on the bronchial tree patency in patients with bronchial asthma]. ( Chyrek-Borowska, S; Rutkowski, R; Siergiejko, Z, 1991) |
| "The effect of a single intravenous dose of pirenzepine on ventilatory indices of 22 asthmatics was studied." | 5.07 | [Effect of pirenzepine, a selective M1 muscarinic receptor antagonist, on the bronchial tree patency in patients with bronchial asthma]. ( Chyrek-Borowska, S; Rutkowski, R; Siergiejko, Z, 1991) |
| " To determine if postsynaptic muscarinic M-1 receptors mediate airway constriction, the action was compared of pirenzepine, that antagonizes selectively muscarinic M-1 receptors, and atropine, that blocks both muscarinic M-1 and M-2 receptors, on bronchial responses to methacholine inhalation in seven asthmatic patients." | 3.67 | Muscarinic M-1 receptors mediate the bronchial hyperresponsiveness during methacholine inhalation. ( Cazzola, M; D'Amato, G; De Novellis, V; Marmo, E; Matera, MG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cazzola, M | 2 |
| Matera, MG | 2 |
| Liccardi, G | 1 |
| Sacerdoti, G | 1 |
| D'Amato, G | 2 |
| Rossi, F | 1 |
| Böhm, M | 1 |
| Gengenbach, S | 1 |
| Hauck, RW | 1 |
| Sunder-Plassmann, L | 1 |
| Erdmann, E | 1 |
| Siergiejko, Z | 1 |
| Rutkowski, R | 1 |
| Chyrek-Borowska, S | 1 |
| De Novellis, V | 1 |
| Marmo, E | 1 |
2 trials available for pirenzepine and Airway Obstruction
| Article | Year |
|---|---|
Effect of telenzepine, an M1-selective muscarinic receptor antagonist, in patients with nocturnal asthma.
Topics: Administration, Oral; Adult; Airway Obstruction; Asthma; Dose-Response Relationship, Drug; Double-Bl | 1994 |
[Effect of pirenzepine, a selective M1 muscarinic receptor antagonist, on the bronchial tree patency in patients with bronchial asthma].
Topics: Adult; Airway Obstruction; Asthma; Bronchi; Bronchodilator Agents; Dose-Response Relationship, Drug; | 1991 |
2 other studies available for pirenzepine and Airway Obstruction
| Article | Year |
|---|---|
Beta-adrenergic receptors and m-cholinergic receptors in human lung. Findings following in vivo and in vitro exposure to the beta-adrenergic receptor agonist, terbutaline.
Topics: Aged; Aged, 80 and over; Airway Obstruction; Dose-Response Relationship, Drug; Down-Regulation; Elec | 1991 |
Muscarinic M-1 receptors mediate the bronchial hyperresponsiveness during methacholine inhalation.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Obstruction; Asthma; Bronchi; Bronchial Spasm; | 1989 |