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pirenzepine and Affective Disorders

pirenzepine has been researched along with Affective Disorders in 13 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Research Excerpts

ExcerptRelevanceReference
" We assessed the differences in risk of developing diabetes mellitus during treatment with olanzapine and risperidone by using patients treated with haloperidol and fluphenazine as control subjects in whom we would not expect to see an increased risk."7.72Comparative study of the development of diabetes mellitus in patients taking risperidone and olanzapine. ( Fuller, MA; Grogg, AL; Secic, M; Shermock, KM, 2003)
"We have previously shown a decrease in [(3)H]pirenzepine binding to M1/M4 muscarinic receptors in the anterior cingulate cortex in schizophrenia but not in major depression or bipolar disorder."3.73M2/M4 muscarinic receptor binding in the anterior cingulate cortex in schizophrenia and mood disorders. ( Huang, XF; Katsifis, A; Yu, Y; Zavitsanou, K, 2005)
" We assessed the differences in risk of developing diabetes mellitus during treatment with olanzapine and risperidone by using patients treated with haloperidol and fluphenazine as control subjects in whom we would not expect to see an increased risk."3.72Comparative study of the development of diabetes mellitus in patients taking risperidone and olanzapine. ( Fuller, MA; Grogg, AL; Secic, M; Shermock, KM, 2003)
"The odds of newly reported type 2 diabetes in patients who received risperidone were not significantly different from those in untreated patients (12-month odds ratio [OR] = 1."1.32Differential effects of antipsychotic agents on the risk of development of type 2 diabetes mellitus in patients with mood disorders. ( Gianfrancesco, F; Grogg, A; Mahmoud, R; Meletiche, D; Wang, RH, 2003)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's9 (69.23)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ztaou, S1
Lhost, J1
Watabe, I1
Torromino, G1
Amalric, M1
Jeon, WJ1
Gibbons, AS1
Dean, B1
Miller, TJ1
Zipursky, RB1
Perkins, D1
Addington, J1
Woods, SW1
Hawkins, KA1
Hoffman, R1
Preda, A1
Epstein, I1
Addington, D1
Lindborg, S1
Marquez, E1
Tohen, M1
Breier, A1
McGlashan, TH1
Gianfrancesco, F1
Grogg, A1
Mahmoud, R1
Wang, RH1
Meletiche, D1
Shelton, RC1
Bokszanska, A1
Martin, G1
Vanstraelen, M1
Holt, G2
Bouras, N2
Taylor, D1
Fuller, MA1
Shermock, KM1
Secic, M1
Grogg, AL1
Zavitsanou, K1
Katsifis, A1
Yu, Y1
Huang, XF1
Williams, H1
Clarke, R1
Martin, J1
Iqbal, MM1
Gundlapalli, SP1
Ryan, WG1
Ryals, T1
Passman, TE1
Buckley, PF1

Reviews

5 reviews available for pirenzepine and Affective Disorders

ArticleYear
The combination of olanzapine and fluoxetine in mood disorders.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:7

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Com

2003
Atypical antipsychotics for treatment of depression in schizophrenia and affective disorders. Collaborative Working Group on Clinical Trial Evaluations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 12

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Comorb

1998
Treatment of special populations with the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 12

    Topics: Adult; Age Factors; Aged; Algorithms; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clini

1998
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
    Southern medical journal, 2001, Volume: 94, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feed

2001
Broad therapeutic uses of atypical antipsychotic medications.
    Biological psychiatry, 2001, Dec-01, Volume: 50, Issue:11

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Child; Child Development Disorders, P

2001

Trials

2 trials available for pirenzepine and Affective Disorders

ArticleYear
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample.
    Schizophrenia research, 2003, May-01, Volume: 61, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Comorbidity; Depressive

2003
Risperidone and olanzapine in adults with intellectual disability: a clinical naturalistic study.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Cognition Disorders; Comorbidity; Di

2003

Other Studies

6 other studies available for pirenzepine and Affective Disorders

ArticleYear
Striatal cholinergic interneurons regulate cognitive and affective dysfunction in partially dopamine-depleted mice.
    The European journal of neuroscience, 2018, Volume: 48, Issue:9

    Topics: Animals; Cholinergic Neurons; Cognitive Dysfunction; Corpus Striatum; Dopamine; Interneurons; Mice;

2018
The use of a modified [3H]4-DAMP radioligand binding assay with increased selectivity for muscarinic M3 receptor shows that cortical CHRM3 levels are not altered in mood disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Dec-02, Volume: 47

    Topics: Adult; Aged; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Humans; Mice; Mice, Knockou

2013
Differential effects of antipsychotic agents on the risk of development of type 2 diabetes mellitus in patients with mood disorders.
    Clinical therapeutics, 2003, Volume: 25, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Data Collection; Diabetes Mellitus, Type 2; Female; Hu

2003
Comparative study of the development of diabetes mellitus in patients taking risperidone and olanzapine.
    Pharmacotherapy, 2003, Volume: 23, Issue:8

    Topics: Antipsychotic Agents; Benzodiazepines; Black People; Diabetes Mellitus; Humans; Male; Mood Disorders

2003
M2/M4 muscarinic receptor binding in the anterior cingulate cortex in schizophrenia and mood disorders.
    Brain research bulletin, 2005, May-15, Volume: 65, Issue:5

    Topics: Adult; Age of Onset; Analysis of Variance; Autoradiography; Brain Mapping; Case-Control Studies; Dos

2005
Use of the atypical antipsychotics Olanzapine and Risperidone in adults with intellectual disability.
    Journal of intellectual disability research : JIDR, 2000, Volume: 44 ( Pt 2)

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Female; Follow-Up St

2000