pirenoxine has been researched along with Cataract, Membranous in 17 studies
pirenoxine: structure given in second source
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated whether and how pirenoxine (PRX) interacts with selenite or calcium ions, as these two ions have been proven respectively a factor leading to the formation of lens cataract." | 7.77 | Ditopic complexation of selenite anions or calcium cations by pirenoxine: an implication for anti-cataractogenesis. ( Chen, CS; Chen, WT; Hu, CC; Huang, FY; Huang, YH; Liao, JH; Lin, IL; Tsai, MH; Wang, SP; Wu, SH; Wu, TH, 2011) |
| "In vitro cataractogenesis assay systems (including UVB/C photo-oxidation of lens crystallins, calpain-induced proteolysis, and selenite/calcium-induced turbidity of lens crystallin solutions) were used to screen the activity of PRX and catalin eye drop solutions." | 7.77 | Role of pirenoxine in the effects of catalin on in vitro ultraviolet-induced lens protein turbidity and selenite-induced cataractogenesis in vivo. ( Chen, HY; Chiu, SJ; Hsu, KY; Hu, CC; Huang, YS; Liao, JH; Lin, IL; Tsai, MH; Wei, TT; Wu, SH; Wu, TH; Wu, WH, 2011) |
| "Cataract is the leading cause of blindness worldwide." | 6.82 | The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. ( Chattipakorn, N; Chattipakorn, SC; Choovuthayakorn, J; Thonusin, C; Upaphong, P, 2022) |
| "Singlet oxygen was produced in chemical reaction NaClO+ H2O2." | 5.28 | [Chemiluminescence decrease of singlet oxygen in NaClO+H2O2 reaction in the presence of different anti-cataract drugs]. ( Formaziuk, VE; Sergienko, VI; Shvachko, AG, 1991) |
| "This study investigated whether and how pirenoxine (PRX) interacts with selenite or calcium ions, as these two ions have been proven respectively a factor leading to the formation of lens cataract." | 3.77 | Ditopic complexation of selenite anions or calcium cations by pirenoxine: an implication for anti-cataractogenesis. ( Chen, CS; Chen, WT; Hu, CC; Huang, FY; Huang, YH; Liao, JH; Lin, IL; Tsai, MH; Wang, SP; Wu, SH; Wu, TH, 2011) |
| "In vitro cataractogenesis assay systems (including UVB/C photo-oxidation of lens crystallins, calpain-induced proteolysis, and selenite/calcium-induced turbidity of lens crystallin solutions) were used to screen the activity of PRX and catalin eye drop solutions." | 3.77 | Role of pirenoxine in the effects of catalin on in vitro ultraviolet-induced lens protein turbidity and selenite-induced cataractogenesis in vivo. ( Chen, HY; Chiu, SJ; Hsu, KY; Hu, CC; Huang, YS; Liao, JH; Lin, IL; Tsai, MH; Wei, TT; Wu, SH; Wu, TH; Wu, WH, 2011) |
| "The government-led "evidence-based guidelines for cataract treatment" labelled pirenoxine and glutathione eye drops, which have been regarded as the standard care for cataracts in Japan, as lacking evidence of effectiveness, causing great upset among ophthalmologists and professional ophthalmology societies." | 3.73 | Why are physicians not persuaded by scientific evidence? A grounded theory interview study. ( Imanaka, Y; Ishizaki, T; Kitano, N; Sekimoto, M; Takahashi, O, 2006) |
| " The concentration of TBA-active products decreased in the presence of carnosine and anticataract drugs (Japanese Catalin, Chinese Baineiting and Finnish Catachrom-OFTAN)." | 3.68 | The antioxidative properties of carnosine and other drugs. ( Boldyrev, AA; Chasovnikova, LV; Formazyuk, VE; Sergienko, VI; Severin, SE, 1990) |
| "Cataract is the leading cause of blindness worldwide." | 2.82 | The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. ( Chattipakorn, N; Chattipakorn, SC; Choovuthayakorn, J; Thonusin, C; Upaphong, P, 2022) |
| "Singlet oxygen was produced in chemical reaction NaClO+ H2O2." | 1.28 | [Chemiluminescence decrease of singlet oxygen in NaClO+H2O2 reaction in the presence of different anti-cataract drugs]. ( Formaziuk, VE; Sergienko, VI; Shvachko, AG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Pearson, A | 1 |
| Munn, Z | 1 |
| Coiera, E | 1 |
| Upaphong, P | 1 |
| Thonusin, C | 1 |
| Choovuthayakorn, J | 1 |
| Chattipakorn, N | 1 |
| Chattipakorn, SC | 1 |
| Liao, Z | 1 |
| Yu, X | 1 |
| Yao, Q | 1 |
| Yi, P | 1 |
| Liao, JH | 2 |
| Chen, CS | 1 |
| Hu, CC | 2 |
| Chen, WT | 1 |
| Wang, SP | 1 |
| Lin, IL | 2 |
| Huang, YH | 1 |
| Tsai, MH | 2 |
| Wu, TH | 2 |
| Huang, FY | 1 |
| Wu, SH | 2 |
| Hsu, KY | 1 |
| Wu, WH | 1 |
| Wei, TT | 1 |
| Huang, YS | 1 |
| Chiu, SJ | 1 |
| Chen, HY | 1 |
| KOMI, T | 1 |
| UCHIDA, S | 1 |
| Kociecki, J | 1 |
| Załecki, K | 1 |
| Wasiewicz-Rager, J | 1 |
| Pecold, K | 1 |
| Sekimoto, M | 1 |
| Imanaka, Y | 1 |
| Kitano, N | 1 |
| Ishizaki, T | 1 |
| Takahashi, O | 1 |
| Angra, SK | 2 |
| Mohan, M | 1 |
| Saini, JS | 1 |
| Bulakh, PM | 3 |
| Chandorkar, AG | 3 |
| Balsara, JJ | 1 |
| Ranade, SM | 1 |
| Albal, MV | 3 |
| Biswas, NR | 1 |
| Mongre, PK | 1 |
| Das, GK | 1 |
| Sen, S | 1 |
| Vajpayee, RB | 1 |
| Ciuffi, M | 1 |
| Neri, S | 1 |
| Franchi-Micheli, S | 1 |
| Failli, P | 1 |
| Zilletti, L | 1 |
| Moncelli, MR | 1 |
| Guidelli, R | 1 |
| Jain, PK | 1 |
| Shvachko, AG | 1 |
| Formaziuk, VE | 1 |
| Sergienko, VI | 2 |
| Chasovnikova, LV | 1 |
| Formazyuk, VE | 1 |
| Boldyrev, AA | 1 |
| Severin, SE | 1 |
| Testa, M | 1 |
| Iuliano, G | 1 |
| Morton, P | 1 |
| Longoni, A | 1 |
1 review available for pirenoxine and Cataract, Membranous
| Article | Year |
|---|---|
The Possible Positive Mechanisms of Pirenoxine in Cataract Formation.
Topics: Antioxidants; Cataract; Humans; Lens, Crystalline; Oxazines | 2022 |
3 trials available for pirenoxine and Cataract, Membranous
| Article | Year |
|---|---|
[Evaluation of effectiveness of Catalin eyedrops in patients with presenile and senile cataract].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cataract; Female; Humans; Male; Middle Aged; Ophthalmic | 2004 |
Medical therapy of cataract (evaluation of Catalin).
Topics: Cataract; Clinical Trials as Topic; Double-Blind Method; Humans; Infant; Infant, Newborn; Oxazines; | 1983 |
Topical benzyl alcohol reduces cataract surgery need: two long-term double blind studies.
Topics: Administration, Topical; Adult; Aged; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Cataract; C | 1987 |
13 other studies available for pirenoxine and Cataract, Membranous
| Article | Year |
|---|---|
Catalin Tufanaru, 1970-2021.
Topics: Cataract; Humans; Lens, Crystalline; Oxazines | 2021 |
Interaction between pirenoxine and bovine serum albumin in aqueous solution.
Topics: Animals; Binding Sites; Cataract; Cattle; Circular Dichroism; Humans; Oxazines; Protein Binding; Pro | 2014 |
Ditopic complexation of selenite anions or calcium cations by pirenoxine: an implication for anti-cataractogenesis.
Topics: Calcium; Cataract; Coordination Complexes; Humans; Lens, Crystalline; Magnetic Resonance Spectroscop | 2011 |
Role of pirenoxine in the effects of catalin on in vitro ultraviolet-induced lens protein turbidity and selenite-induced cataractogenesis in vivo.
Topics: Animals; Animals, Newborn; Calcium; Calpain; Cataract; Dose-Response Relationship, Drug; Drug Dosage | 2011 |
[On the effectiveness of the collyrium Catalin in senile cataract].
Topics: Cataract; Humans; Oxazines | 1962 |
Why are physicians not persuaded by scientific evidence? A grounded theory interview study.
Topics: Aged; Attitude of Health Personnel; Awareness; Cataract; Clinical Competence; Drug Utilization; Evid | 2006 |
Effect of 'catalin' an anticataract agent on alloxan induced hyperglycaemia and diabetic cataract in rats.
Topics: Alloxan; Animals; Cataract; Diabetes Mellitus, Experimental; Female; Hyperglycemia; Male; Oxazines; | 1980 |
Evaluation of catalin, Succus Cineraria maritima and Catobell in goat lens cultures.
Topics: Animals; Cataract; Goats; In Vitro Techniques; Lens, Crystalline; Oxazines | 1981 |
Animal study on the effects of catalin on aftercataract and posterior capsule opacification.
Topics: Animals; Capsulorhexis; Cataract; Lens Capsule, Crystalline; Ophthalmic Solutions; Oxazines; Rabbits | 1999 |
Protective effect of pirenoxine and U74389F on induced lipid peroxidation in mammalian lenses. An in vitro, ex vivo and in vivo study.
Topics: Animals; Antioxidants; Cataract; Guinea Pigs; Hemoglobins; In Vitro Techniques; Iron; Lens, Crystall | 1999 |
Hypoglycaemic effect of 'Catalin' an anti-cataract agent in rabbits, (a preliminary study).
Topics: Animals; Blood Glucose; Cataract; Depression, Chemical; Female; Male; Oxazines; Picolinic Acids; Rab | 1978 |
[Chemiluminescence decrease of singlet oxygen in NaClO+H2O2 reaction in the presence of different anti-cataract drugs].
Topics: Acridines; Cataract; Chlorides; Hydrogen Peroxide; Luminescent Measurements; Ophthalmic Solutions; O | 1991 |
The antioxidative properties of carnosine and other drugs.
Topics: Acridines; alpha-Tocopherol; Animals; Aspirin; Carnosine; Cataract; Dipeptides; Ferrous Compounds; K | 1990 |