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pirenoxine and Cataract, Membranous

pirenoxine has been researched along with Cataract, Membranous in 17 studies

pirenoxine: structure given in second source

Research Excerpts

ExcerptRelevanceReference
"This study investigated whether and how pirenoxine (PRX) interacts with selenite or calcium ions, as these two ions have been proven respectively a factor leading to the formation of lens cataract."7.77Ditopic complexation of selenite anions or calcium cations by pirenoxine: an implication for anti-cataractogenesis. ( Chen, CS; Chen, WT; Hu, CC; Huang, FY; Huang, YH; Liao, JH; Lin, IL; Tsai, MH; Wang, SP; Wu, SH; Wu, TH, 2011)
"In vitro cataractogenesis assay systems (including UVB/C photo-oxidation of lens crystallins, calpain-induced proteolysis, and selenite/calcium-induced turbidity of lens crystallin solutions) were used to screen the activity of PRX and catalin eye drop solutions."7.77Role of pirenoxine in the effects of catalin on in vitro ultraviolet-induced lens protein turbidity and selenite-induced cataractogenesis in vivo. ( Chen, HY; Chiu, SJ; Hsu, KY; Hu, CC; Huang, YS; Liao, JH; Lin, IL; Tsai, MH; Wei, TT; Wu, SH; Wu, TH; Wu, WH, 2011)
"Cataract is the leading cause of blindness worldwide."6.82The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. ( Chattipakorn, N; Chattipakorn, SC; Choovuthayakorn, J; Thonusin, C; Upaphong, P, 2022)
"Singlet oxygen was produced in chemical reaction NaClO+ H2O2."5.28[Chemiluminescence decrease of singlet oxygen in NaClO+H2O2 reaction in the presence of different anti-cataract drugs]. ( Formaziuk, VE; Sergienko, VI; Shvachko, AG, 1991)
"This study investigated whether and how pirenoxine (PRX) interacts with selenite or calcium ions, as these two ions have been proven respectively a factor leading to the formation of lens cataract."3.77Ditopic complexation of selenite anions or calcium cations by pirenoxine: an implication for anti-cataractogenesis. ( Chen, CS; Chen, WT; Hu, CC; Huang, FY; Huang, YH; Liao, JH; Lin, IL; Tsai, MH; Wang, SP; Wu, SH; Wu, TH, 2011)
"In vitro cataractogenesis assay systems (including UVB/C photo-oxidation of lens crystallins, calpain-induced proteolysis, and selenite/calcium-induced turbidity of lens crystallin solutions) were used to screen the activity of PRX and catalin eye drop solutions."3.77Role of pirenoxine in the effects of catalin on in vitro ultraviolet-induced lens protein turbidity and selenite-induced cataractogenesis in vivo. ( Chen, HY; Chiu, SJ; Hsu, KY; Hu, CC; Huang, YS; Liao, JH; Lin, IL; Tsai, MH; Wei, TT; Wu, SH; Wu, TH; Wu, WH, 2011)
"The government-led "evidence-based guidelines for cataract treatment" labelled pirenoxine and glutathione eye drops, which have been regarded as the standard care for cataracts in Japan, as lacking evidence of effectiveness, causing great upset among ophthalmologists and professional ophthalmology societies."3.73Why are physicians not persuaded by scientific evidence? A grounded theory interview study. ( Imanaka, Y; Ishizaki, T; Kitano, N; Sekimoto, M; Takahashi, O, 2006)
" The concentration of TBA-active products decreased in the presence of carnosine and anticataract drugs (Japanese Catalin, Chinese Baineiting and Finnish Catachrom-OFTAN)."3.68The antioxidative properties of carnosine and other drugs. ( Boldyrev, AA; Chasovnikova, LV; Formazyuk, VE; Sergienko, VI; Severin, SE, 1990)
"Cataract is the leading cause of blindness worldwide."2.82The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. ( Chattipakorn, N; Chattipakorn, SC; Choovuthayakorn, J; Thonusin, C; Upaphong, P, 2022)
"Singlet oxygen was produced in chemical reaction NaClO+ H2O2."1.28[Chemiluminescence decrease of singlet oxygen in NaClO+H2O2 reaction in the presence of different anti-cataract drugs]. ( Formaziuk, VE; Sergienko, VI; Shvachko, AG, 1991)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's4 (23.53)18.2507
2000's2 (11.76)29.6817
2010's3 (17.65)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Pearson, A1
Munn, Z1
Coiera, E1
Upaphong, P1
Thonusin, C1
Choovuthayakorn, J1
Chattipakorn, N1
Chattipakorn, SC1
Liao, Z1
Yu, X1
Yao, Q1
Yi, P1
Liao, JH2
Chen, CS1
Hu, CC2
Chen, WT1
Wang, SP1
Lin, IL2
Huang, YH1
Tsai, MH2
Wu, TH2
Huang, FY1
Wu, SH2
Hsu, KY1
Wu, WH1
Wei, TT1
Huang, YS1
Chiu, SJ1
Chen, HY1
KOMI, T1
UCHIDA, S1
Kociecki, J1
ZaƂecki, K1
Wasiewicz-Rager, J1
Pecold, K1
Sekimoto, M1
Imanaka, Y1
Kitano, N1
Ishizaki, T1
Takahashi, O1
Angra, SK2
Mohan, M1
Saini, JS1
Bulakh, PM3
Chandorkar, AG3
Balsara, JJ1
Ranade, SM1
Albal, MV3
Biswas, NR1
Mongre, PK1
Das, GK1
Sen, S1
Vajpayee, RB1
Ciuffi, M1
Neri, S1
Franchi-Micheli, S1
Failli, P1
Zilletti, L1
Moncelli, MR1
Guidelli, R1
Jain, PK1
Shvachko, AG1
Formaziuk, VE1
Sergienko, VI2
Chasovnikova, LV1
Formazyuk, VE1
Boldyrev, AA1
Severin, SE1
Testa, M1
Iuliano, G1
Morton, P1
Longoni, A1

Reviews

1 review available for pirenoxine and Cataract, Membranous

ArticleYear
The Possible Positive Mechanisms of Pirenoxine in Cataract Formation.
    International journal of molecular sciences, 2022, Aug-21, Volume: 23, Issue:16

    Topics: Antioxidants; Cataract; Humans; Lens, Crystalline; Oxazines

2022

Trials

3 trials available for pirenoxine and Cataract, Membranous

ArticleYear
[Evaluation of effectiveness of Catalin eyedrops in patients with presenile and senile cataract].
    Klinika oczna, 2004, Volume: 106, Issue:6

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cataract; Female; Humans; Male; Middle Aged; Ophthalmic

2004
Medical therapy of cataract (evaluation of Catalin).
    Indian journal of ophthalmology, 1983, Volume: 31, Issue:1

    Topics: Cataract; Clinical Trials as Topic; Double-Blind Method; Humans; Infant; Infant, Newborn; Oxazines;

1983
Topical benzyl alcohol reduces cataract surgery need: two long-term double blind studies.
    Journal of ocular pharmacology, 1987,Fall, Volume: 3, Issue:3

    Topics: Administration, Topical; Adult; Aged; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Cataract; C

1987

Other Studies

13 other studies available for pirenoxine and Cataract, Membranous

ArticleYear
Catalin Tufanaru, 1970-2021.
    JBI evidence synthesis, 2021, 09-01, Volume: 19, Issue:9

    Topics: Cataract; Humans; Lens, Crystalline; Oxazines

2021
Interaction between pirenoxine and bovine serum albumin in aqueous solution.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Aug-14, Volume: 129

    Topics: Animals; Binding Sites; Cataract; Cattle; Circular Dichroism; Humans; Oxazines; Protein Binding; Pro

2014
Ditopic complexation of selenite anions or calcium cations by pirenoxine: an implication for anti-cataractogenesis.
    Inorganic chemistry, 2011, Jan-03, Volume: 50, Issue:1

    Topics: Calcium; Cataract; Coordination Complexes; Humans; Lens, Crystalline; Magnetic Resonance Spectroscop

2011
Role of pirenoxine in the effects of catalin on in vitro ultraviolet-induced lens protein turbidity and selenite-induced cataractogenesis in vivo.
    Molecular vision, 2011, Volume: 17

    Topics: Animals; Animals, Newborn; Calcium; Calpain; Cataract; Dose-Response Relationship, Drug; Drug Dosage

2011
[On the effectiveness of the collyrium Catalin in senile cataract].
    Rinsho ganka. Japanese journal of clinical ophthalmology, 1962, Volume: 16

    Topics: Cataract; Humans; Oxazines

1962
Why are physicians not persuaded by scientific evidence? A grounded theory interview study.
    BMC health services research, 2006, Jul-27, Volume: 6

    Topics: Aged; Attitude of Health Personnel; Awareness; Cataract; Clinical Competence; Drug Utilization; Evid

2006
Effect of 'catalin' an anticataract agent on alloxan induced hyperglycaemia and diabetic cataract in rats.
    Indian journal of ophthalmology, 1980, Volume: 28, Issue:1

    Topics: Alloxan; Animals; Cataract; Diabetes Mellitus, Experimental; Female; Hyperglycemia; Male; Oxazines;

1980
Evaluation of catalin, Succus Cineraria maritima and Catobell in goat lens cultures.
    Indian journal of ophthalmology, 1981, Volume: 29, Issue:3

    Topics: Animals; Cataract; Goats; In Vitro Techniques; Lens, Crystalline; Oxazines

1981
Animal study on the effects of catalin on aftercataract and posterior capsule opacification.
    Ophthalmic research, 1999, Volume: 31, Issue:2

    Topics: Animals; Capsulorhexis; Cataract; Lens Capsule, Crystalline; Ophthalmic Solutions; Oxazines; Rabbits

1999
Protective effect of pirenoxine and U74389F on induced lipid peroxidation in mammalian lenses. An in vitro, ex vivo and in vivo study.
    Experimental eye research, 1999, Volume: 68, Issue:3

    Topics: Animals; Antioxidants; Cataract; Guinea Pigs; Hemoglobins; In Vitro Techniques; Iron; Lens, Crystall

1999
Hypoglycaemic effect of 'Catalin' an anti-cataract agent in rabbits, (a preliminary study).
    Indian journal of ophthalmology, 1978, Volume: 26, Issue:1

    Topics: Animals; Blood Glucose; Cataract; Depression, Chemical; Female; Male; Oxazines; Picolinic Acids; Rab

1978
[Chemiluminescence decrease of singlet oxygen in NaClO+H2O2 reaction in the presence of different anti-cataract drugs].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:7

    Topics: Acridines; Cataract; Chlorides; Hydrogen Peroxide; Luminescent Measurements; Ophthalmic Solutions; O

1991
The antioxidative properties of carnosine and other drugs.
    Biochemistry international, 1990, Volume: 20, Issue:6

    Topics: Acridines; alpha-Tocopherol; Animals; Aspirin; Carnosine; Cataract; Dipeptides; Ferrous Compounds; K

1990