pirbuterol has been researched along with Asthma in 36 studies
pirbuterol: structure
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a controlled clinical crossover trial, the therapeutic effect of pirbuterol (CAS 38677-81-5) in the Autohaler was compared to that of salbutamol in a customary metered-dose aerosol in 17 children with asthma." | 9.07 | Clinical efficacy of two beta 2-sympathicomimetics in different inhalers in children with asthma. Comparison of pirbuterol in a breath-actuated inhaler and salbutamol in a customary metered-dose inhaler. ( Kroll, VM; Schneider, B; Völkl, KP; Wiesemann, HG, 1991) |
| "Pirbuterol, a new anti-asthmatic compound, was tested in 21 male outpatients with reversible bronchospastic disease during 12 months in different dosis regimens in order to determine the extent and duration of bronchodilator activity, the optimum multiple dose-schedule, the incidence, type and degree of side effects, and the cardiovascular as well as hematologic, renal and hepatic function after oral administration." | 9.04 | Pirbuterol in the treatment of bronchial asthma. ( Beumer, HM, 1979) |
| "In a single blind crossover study 12 asthmatics received in randomised order single doses of pirbuterol (200 and 400 microgram), salbutamol (200 microgram) and placebo-aerosols, in order to determine the extent and duration of bronchodilator activity, the optimum dosage, the incidence, type and degree of side effects and the cardiovascular as well as hematologic, renal and hepatic functions after inhalative administration." | 9.04 | Comparative investigations on pirbuterol, salbutamol and placebo aerosols in bronchial asthma. ( Beumer, HM, 1979) |
| "In a single blind cross-over study 12 patients with asthma received in randomised order aerosols of pirbuterol 400 micrograms, salbutamol 200 micrograms or placebo." | 9.04 | [Comparative studies on pirbuterol, salbutamol and a placebo administered as an aerosol in asthmatic patients]. ( Verstraeten, JM, 1978) |
| "We studied the effects of an oral beta2 selective bronchodilator, pirbuterol, in 12 male asthmatic patients over periods ranging from 6 to 23 months (mean, 13." | 7.66 | Long-term oral bronchodilator therapy of asthma with pirbuterol. ( Burki, NK; Diamond, L, 1978) |
| "In a double-blind trial the effects on ventilatory function (FEV1), heart rate and blood pressure of oral pirbuterol and oral salbutamol in various single doses were studied in ten patients with chronic asthma." | 7.65 | Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics. ( Grant, IW; Pocock, SJ; Willey, RF, 1976) |
| "The animal and human pharmacology of several new drugs (prazosin, trimazosin, pirbuterol, and carbazeran) useful in the treatment of congestive heart failure (CHF) is delineated in relation to the pharmacology of other agents employed for CHF management." | 6.15 | Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure. ( Baird, JR; Blackburn, KJ; Cambridge, D; Constantine, JW; Ghaly, MS; Hayden, ML; McIlhenny, HM; Moore, PF; Olukotun, AY; Pullman, LG; Salsburg, DS; Saxton, CA; Shevde, S; Taylor, CR, 1981) |
| " We compared bronchodilator effect of pirbuterol acetate (Maxair), inhaled from Autohaler and a standard MDI, under conditions that ensured optimal technique in 20 patients with asthma." | 5.07 | A device for overcoming discoordination with metered-dose inhalers. ( Crook, D; Hahn, M; Mukai, DS; Novey, HS; Schecker, MH; Wilson, AF, 1993) |
| "Pirbuterol is a selective beta-2 adrenergic agonist that is indicated for the treatment of bronchospasm in patients with asthma." | 5.07 | Double-blind, clinical efficacy study comparing 400 micrograms of pirbuterol versus placebo delivered by a breath-actuated aerosol inhaler. ( Ekholm, BP; Tinkelman, DG; Vanden Burgt, JA, 1994) |
| "In this investigation we evaluated the effect of increasing dosage, using an inhaled beta-2 specific agonist, pirbuterol, administered by a metered dose inhaler on pulmonary function, tremor, and cardiovascular parameters in nonacute adult asthmatic patients." | 5.07 | Effect of increasing dosage of an inhaled beta-2 specific agonist on pulmonary function, tremor, and cardiovascular indices. ( Lutz, C; Tinkelman, DG, 1992) |
| "In a controlled clinical crossover trial, the therapeutic effect of pirbuterol (CAS 38677-81-5) in the Autohaler was compared to that of salbutamol in a customary metered-dose aerosol in 17 children with asthma." | 5.07 | Clinical efficacy of two beta 2-sympathicomimetics in different inhalers in children with asthma. Comparison of pirbuterol in a breath-actuated inhaler and salbutamol in a customary metered-dose inhaler. ( Kroll, VM; Schneider, B; Völkl, KP; Wiesemann, HG, 1991) |
| "Combined bronchodilator effects of the beta 2-agonist pirbuterol and theophylline were studied in anaesthetized rats and in asthmatic outpatients." | 5.05 | Bronchodilator combinations in animals and in man. ( Mattila, MJ; Ruotsalainen, EM; Salonen, RO, 1985) |
| "Pirbuterol, a new anti-asthmatic compound, was tested in 21 male outpatients with reversible bronchospastic disease during 12 months in different dosis regimens in order to determine the extent and duration of bronchodilator activity, the optimum multiple dose-schedule, the incidence, type and degree of side effects, and the cardiovascular as well as hematologic, renal and hepatic function after oral administration." | 5.04 | Pirbuterol in the treatment of bronchial asthma. ( Beumer, HM, 1979) |
| "In a single blind crossover study 12 asthmatics received in randomised order single doses of pirbuterol (200 and 400 microgram), salbutamol (200 microgram) and placebo-aerosols, in order to determine the extent and duration of bronchodilator activity, the optimum dosage, the incidence, type and degree of side effects and the cardiovascular as well as hematologic, renal and hepatic functions after inhalative administration." | 5.04 | Comparative investigations on pirbuterol, salbutamol and placebo aerosols in bronchial asthma. ( Beumer, HM, 1979) |
| "In a single blind cross-over study 12 patients with asthma received in randomised order aerosols of pirbuterol 400 micrograms, salbutamol 200 micrograms or placebo." | 5.04 | [Comparative studies on pirbuterol, salbutamol and a placebo administered as an aerosol in asthmatic patients]. ( Verstraeten, JM, 1978) |
| "The acute pulmonary and cardiovascular effects of pirbuterol dihydrochloride 10 mg and 15 mg, a new orally active beta 2-selective sympathomimetic agent, were compared with those of placebo and metaproterenol 20 mg over a period of seven hours in 24 stable asthmatics." | 5.04 | Acute bronchial and cardiovascular effects of oral pirbuterol and metaproterenol. ( Child, JS; Ence, TJ; Ho, D; Tashkin, DP, 1979) |
| "This paper reviews the impact of the use of technologically dissimilar beta-agonist aerosols--the Maxair Autohaler (pirbuterol acetate) breath-actuated aerosol and the traditional albuterol press-and-breathe inhaler-on the treatment costs of asthma." | 3.70 | The technology of metered-dose inhalers and treatment costs in asthma: a retrospective study of breath actuation versus traditional press-and-breathe inhalers. ( Langley, PC, 1999) |
| "We studied the effects of an oral beta2 selective bronchodilator, pirbuterol, in 12 male asthmatic patients over periods ranging from 6 to 23 months (mean, 13." | 3.66 | Long-term oral bronchodilator therapy of asthma with pirbuterol. ( Burki, NK; Diamond, L, 1978) |
| "In a double-blind trial the effects on ventilatory function (FEV1), heart rate and blood pressure of oral pirbuterol and oral salbutamol in various single doses were studied in ten patients with chronic asthma." | 3.65 | Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics. ( Grant, IW; Pocock, SJ; Willey, RF, 1976) |
| " Our conclusion is that pirbuterol is at least as effective and safe under conditions of chronic administration to asthmatics as metaproterenol and therefore can be considered a suitable alternative for therapy." | 2.67 | Comparison of safety and efficacy of inhaled pirbuterol with metaproterenol. ( Brandon, ML; Grieco, M; Hudson, L; Rosenthal, RR; Spector, SL; Tashkin, D; Tinkelman, DG; Votteri, B, 1990) |
| "Pirbuterol is a beta-adrenoceptor agonist which differs structurally from salbutamol in the substitution of a pyridine ring for the benzene ring." | 2.37 | Pirbuterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible bronchospastic disease. ( Brogden, RN; Richards, DM, 1985) |
| " The characteristics of the oral route are easy usage, precise dosage and assured effects." | 1.27 | Oral beta 2-selective adrenergic bronchodilators. ( Daniotti, S; Dottorini, M; Grassi, V; Schiassi, M; Tantucci, C, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (58.33) | 18.7374 |
| 1990's | 10 (27.78) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bianchi, M | 1 |
| Clavenna, A | 1 |
| Bonati, M | 1 |
| Willey, RF | 2 |
| Grant, IW | 3 |
| Pocock, SJ | 1 |
| Weinberger, M | 1 |
| Abu-Hasan, M | 1 |
| Yaegashi, M | 1 |
| Yalamanchili, VA | 1 |
| Kaza, V | 1 |
| Weedon, J | 1 |
| Heurich, AE | 1 |
| Akerman, MJ | 1 |
| Bonniaud, P | 1 |
| Favrolt, N | 1 |
| Collet, E | 1 |
| Dumas, JP | 1 |
| Guilloux, L | 1 |
| Pauli, G | 1 |
| Camus, P | 1 |
| Seed, MJ | 1 |
| Agius, RM | 1 |
| Crompton, GK | 1 |
| Beumer, HM | 4 |
| Viallat, JR | 1 |
| Boutin, C | 1 |
| Razzouk, H | 1 |
| Aebischer, JC | 1 |
| Benoit, RC | 1 |
| Scherrer, M | 1 |
| Taylor, CR | 1 |
| Baird, JR | 1 |
| Blackburn, KJ | 1 |
| Cambridge, D | 1 |
| Constantine, JW | 1 |
| Ghaly, MS | 1 |
| Hayden, ML | 1 |
| McIlhenny, HM | 1 |
| Moore, PF | 1 |
| Olukotun, AY | 1 |
| Pullman, LG | 1 |
| Salsburg, DS | 1 |
| Saxton, CA | 1 |
| Shevde, S | 1 |
| Littner, MR | 1 |
| Tashkin, DP | 2 |
| Calvarese, B | 1 |
| Bautista, M | 1 |
| Brandon, ML | 2 |
| Schecker, MH | 1 |
| Wilson, AF | 1 |
| Mukai, DS | 1 |
| Hahn, M | 2 |
| Crook, D | 1 |
| Novey, HS | 1 |
| Tinkelman, DG | 3 |
| Vanden Burgt, JA | 1 |
| Ekholm, BP | 1 |
| Bronsky, EA | 1 |
| Debelic, M | 1 |
| Pujet, JC | 1 |
| Chinet, TC | 1 |
| Silverman, R | 1 |
| Sellers, J | 1 |
| Greene, S | 1 |
| Flaster, E | 1 |
| Colice, G | 1 |
| Langley, PC | 1 |
| Kelloway, JS | 1 |
| Wyatt, R | 1 |
| Paterson, IC | 1 |
| Verstraeten, JM | 1 |
| Ence, TJ | 1 |
| Ho, D | 1 |
| Child, JS | 1 |
| Burki, NK | 1 |
| Diamond, L | 1 |
| Lutz, C | 1 |
| Völkl, KP | 1 |
| Kroll, VM | 1 |
| Wiesemann, HG | 1 |
| Schneider, B | 1 |
| Grieco, M | 1 |
| Hudson, L | 1 |
| Rosenthal, RR | 1 |
| Spector, SL | 1 |
| Tashkin, D | 1 |
| Votteri, B | 1 |
| Chodosh, S | 1 |
| Crooks, LA | 1 |
| Tuck, J | 1 |
| Richards, DM | 1 |
| Brogden, RN | 1 |
| Ugriumova, MO | 1 |
| Grassi, V | 1 |
| Daniotti, S | 1 |
| Schiassi, M | 1 |
| Dottorini, M | 1 |
| Tantucci, C | 1 |
| Mattila, MJ | 1 |
| Salonen, RO | 1 |
| Ruotsalainen, EM | 1 |
| Steen, SN | 1 |
| Ziment, I | 1 |
| Thomas, JS | 1 |
4 reviews available for pirbuterol and Asthma
| Article | Year |
|---|---|
Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period.
Topics: Acetates; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bude | 2010 |
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Dr | 1981 |
Pirbuterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible bronchospastic disease.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Biotransformation; Bronchial Spasm; Bronchodilator Agents | 1985 |
[State of the adrenoreceptor system and drug therapy].
Topics: Adrenergic beta-Agonists; Animals; Asthma; Dobutamine; Ethanolamines; Humans; Mice; Propranolol; Rat | 1985 |
21 trials available for pirbuterol and Asthma
| Article | Year |
|---|---|
Pirbuterol.
Topics: Albuterol; Animals; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Et | 1984 |
Pirbuterol versus orciprenaline aerosols in the treatment of bronchial asthma.
Topics: Adult; Aerosols; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Clinical Trials as Topic; Doub | 1983 |
Pirbuterol syrup--treatment of asthma in children in a residential asthma clinic.
Topics: Asthma; Child; Clinical Trials as Topic; Ethanolamines; Female; Humans; Male; Respiratory Function T | 1984 |
[Pirbuterol and salbutamol aerosol for exercise-induced bronchoconstriction].
Topics: Adult; Aerosols; Albuterol; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Ethanolamines; | 1984 |
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Dr | 1981 |
Acute bronchial and cardiovascular effects of increasing doses of pirbuterol acetate aerosol in asthma.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Blood Pressure; Bronchi; Bronchodilator Agents; Cardiovas | 1982 |
A device for overcoming discoordination with metered-dose inhalers.
Topics: Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Ethanolamines; Female; Forced Expiratory Vol | 1993 |
Double-blind, clinical efficacy study comparing 400 micrograms of pirbuterol versus placebo delivered by a breath-actuated aerosol inhaler.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Double-Blind Method | 1994 |
Comparison of the Maxair Autohaler to wet nebulizer in patients with acute asthma.
Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchodilator Agents | 1998 |
A cost-effectiveness analysis of breath-actuated metered-dose inhalers.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Child; Cost-B | 1997 |
Effects of prolonged administration of pirbuterol by mouth in chronic asthma.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Chronic Disease; Cl | 1977 |
Pirbuterol in the treatment of bronchial asthma.
Topics: Adolescent; Adult; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Clinical Trials as Topic; Et | 1979 |
Comparative investigations on pirbuterol, salbutamol and placebo aerosols in bronchial asthma.
Topics: Adolescent; Adult; Aerosols; Aged; Albuterol; Asthma; Bronchodilator Agents; Clinical Trials as Topi | 1979 |
[Comparative studies on pirbuterol, salbutamol and a placebo administered as an aerosol in asthmatic patients].
Topics: Adult; Aerosols; Aged; Albuterol; Asthma; Bronchodilator Agents; Ethanolamines; Evaluation Studies a | 1978 |
Acute bronchial and cardiovascular effects of oral pirbuterol and metaproterenol.
Topics: Acute Disease; Adult; Aged; Airway Obstruction; Asthma; Bronchodilator Agents; Cardiovascular System | 1979 |
Effect of increasing dosage of an inhaled beta-2 specific agonist on pulmonary function, tremor, and cardiovascular indices.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Ethanolamines; Hemodynam | 1992 |
Clinical efficacy of two beta 2-sympathicomimetics in different inhalers in children with asthma. Comparison of pirbuterol in a breath-actuated inhaler and salbutamol in a customary metered-dose inhaler.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Asthma; Child; Ethanolamines; Femal | 1991 |
Comparison of safety and efficacy of inhaled pirbuterol with metaproterenol.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Double | 1990 |
Comparative effects of pirbuterol acetate, metaproterenol, and placebo aerosols on pulmonary function and incidence of cardiac ectopy.
Topics: Adult; Aerosols; Aged; Asthma; Bronchitis; Bronchodilator Agents; Cardiac Complexes, Premature; Elec | 1989 |
Bronchodilator combinations in animals and in man.
Topics: Adult; Animals; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Drug C | 1985 |
Pyrbuterol: a new bronchodilator. Phase I-single dose study.
Topics: Adult; Aged; Airway Resistance; Asthma; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Buty | 1974 |
12 other studies available for pirbuterol and Asthma
| Article | Year |
|---|---|
Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics.
Topics: Administration, Oral; Aged; Albuterol; Asthma; Blood Pressure; Bronchodilator Agents; Dose-Response | 1976 |
Life-threatening asthma during treatment with salmeterol.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Albuterol; Androstadienes; Asthma; | 2006 |
The utility of the forced oscillation technique in assessing bronchodilator responsiveness in patients with asthma.
Topics: Adult; Airway Resistance; Anthropometry; Asthma; Bronchodilator Agents; Ethanolamines; Female; Force | 2007 |
Salbutamol, terbutaline and pirbuterol allergy in an asthmatic patient.
Topics: Adult; Aerosols; Albuterol; Asthma; Bronchoconstriction; Bronchodilator Agents; Drug Hypersensitivit | 2007 |
Paradoxical asthma hazard of short-acting beta2-agonists.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchoconstrictio | 2008 |
Long-term treatment of bronchial asthma with pirbuterol aerosol.
Topics: Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Ethanolamines; Humans; Lung; Middle Aged | 1983 |
Pirbuterol vs. hydroxyzine vs. theophylline vs. placebo in the treatment of bronchial asthma.
Topics: Adolescent; Adult; Asthma; Blood Pressure; Double-Blind Method; Ethanolamines; Female; Forced Expira | 1980 |
Ease-of-use study of pirbuterol acetate in the Autohaler actuator in three countries: the United States, Germany, and France.
Topics: Adult; Asthma; Bronchodilator Agents; Ethanolamines; Evaluation Studies as Topic; Female; France; Ge | 1993 |
Management of chronic obstructive pulmonary disease.
Topics: Albuterol; Asthma; Bronchodilator Agents; Ethanolamines; Humans | 1993 |
The technology of metered-dose inhalers and treatment costs in asthma: a retrospective study of breath actuation versus traditional press-and-breathe inhalers.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator Agents; Cost Savings; Costs and Cost Ana | 1999 |
Long-term oral bronchodilator therapy of asthma with pirbuterol.
Topics: Administration, Oral; Adult; Aged; Asthma; Bronchodilator Agents; Ethanolamines; Humans; Male; Middl | 1978 |
Oral beta 2-selective adrenergic bronchodilators.
Topics: Administration, Oral; Adrenergic beta-Agonists; Aged; Asthma; Bronchodilator Agents; Child; Clenbute | 1986 |