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pirbuterol and Asthma, Bronchial

pirbuterol has been researched along with Asthma, Bronchial in 36 studies

pirbuterol: structure

Research Excerpts

ExcerptRelevanceReference
"In a controlled clinical crossover trial, the therapeutic effect of pirbuterol (CAS 38677-81-5) in the Autohaler was compared to that of salbutamol in a customary metered-dose aerosol in 17 children with asthma."9.07Clinical efficacy of two beta 2-sympathicomimetics in different inhalers in children with asthma. Comparison of pirbuterol in a breath-actuated inhaler and salbutamol in a customary metered-dose inhaler. ( Kroll, VM; Schneider, B; Völkl, KP; Wiesemann, HG, 1991)
"Pirbuterol, a new anti-asthmatic compound, was tested in 21 male outpatients with reversible bronchospastic disease during 12 months in different dosis regimens in order to determine the extent and duration of bronchodilator activity, the optimum multiple dose-schedule, the incidence, type and degree of side effects, and the cardiovascular as well as hematologic, renal and hepatic function after oral administration."9.04Pirbuterol in the treatment of bronchial asthma. ( Beumer, HM, 1979)
"In a single blind crossover study 12 asthmatics received in randomised order single doses of pirbuterol (200 and 400 microgram), salbutamol (200 microgram) and placebo-aerosols, in order to determine the extent and duration of bronchodilator activity, the optimum dosage, the incidence, type and degree of side effects and the cardiovascular as well as hematologic, renal and hepatic functions after inhalative administration."9.04Comparative investigations on pirbuterol, salbutamol and placebo aerosols in bronchial asthma. ( Beumer, HM, 1979)
"In a single blind cross-over study 12 patients with asthma received in randomised order aerosols of pirbuterol 400 micrograms, salbutamol 200 micrograms or placebo."9.04[Comparative studies on pirbuterol, salbutamol and a placebo administered as an aerosol in asthmatic patients]. ( Verstraeten, JM, 1978)
"We studied the effects of an oral beta2 selective bronchodilator, pirbuterol, in 12 male asthmatic patients over periods ranging from 6 to 23 months (mean, 13."7.66Long-term oral bronchodilator therapy of asthma with pirbuterol. ( Burki, NK; Diamond, L, 1978)
"In a double-blind trial the effects on ventilatory function (FEV1), heart rate and blood pressure of oral pirbuterol and oral salbutamol in various single doses were studied in ten patients with chronic asthma."7.65Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics. ( Grant, IW; Pocock, SJ; Willey, RF, 1976)
"The animal and human pharmacology of several new drugs (prazosin, trimazosin, pirbuterol, and carbazeran) useful in the treatment of congestive heart failure (CHF) is delineated in relation to the pharmacology of other agents employed for CHF management."6.15Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure. ( Baird, JR; Blackburn, KJ; Cambridge, D; Constantine, JW; Ghaly, MS; Hayden, ML; McIlhenny, HM; Moore, PF; Olukotun, AY; Pullman, LG; Salsburg, DS; Saxton, CA; Shevde, S; Taylor, CR, 1981)
" We compared bronchodilator effect of pirbuterol acetate (Maxair), inhaled from Autohaler and a standard MDI, under conditions that ensured optimal technique in 20 patients with asthma."5.07A device for overcoming discoordination with metered-dose inhalers. ( Crook, D; Hahn, M; Mukai, DS; Novey, HS; Schecker, MH; Wilson, AF, 1993)
"Pirbuterol is a selective beta-2 adrenergic agonist that is indicated for the treatment of bronchospasm in patients with asthma."5.07Double-blind, clinical efficacy study comparing 400 micrograms of pirbuterol versus placebo delivered by a breath-actuated aerosol inhaler. ( Ekholm, BP; Tinkelman, DG; Vanden Burgt, JA, 1994)
"In this investigation we evaluated the effect of increasing dosage, using an inhaled beta-2 specific agonist, pirbuterol, administered by a metered dose inhaler on pulmonary function, tremor, and cardiovascular parameters in nonacute adult asthmatic patients."5.07Effect of increasing dosage of an inhaled beta-2 specific agonist on pulmonary function, tremor, and cardiovascular indices. ( Lutz, C; Tinkelman, DG, 1992)
"In a controlled clinical crossover trial, the therapeutic effect of pirbuterol (CAS 38677-81-5) in the Autohaler was compared to that of salbutamol in a customary metered-dose aerosol in 17 children with asthma."5.07Clinical efficacy of two beta 2-sympathicomimetics in different inhalers in children with asthma. Comparison of pirbuterol in a breath-actuated inhaler and salbutamol in a customary metered-dose inhaler. ( Kroll, VM; Schneider, B; Völkl, KP; Wiesemann, HG, 1991)
"Combined bronchodilator effects of the beta 2-agonist pirbuterol and theophylline were studied in anaesthetized rats and in asthmatic outpatients."5.05Bronchodilator combinations in animals and in man. ( Mattila, MJ; Ruotsalainen, EM; Salonen, RO, 1985)
"Pirbuterol, a new anti-asthmatic compound, was tested in 21 male outpatients with reversible bronchospastic disease during 12 months in different dosis regimens in order to determine the extent and duration of bronchodilator activity, the optimum multiple dose-schedule, the incidence, type and degree of side effects, and the cardiovascular as well as hematologic, renal and hepatic function after oral administration."5.04Pirbuterol in the treatment of bronchial asthma. ( Beumer, HM, 1979)
"In a single blind crossover study 12 asthmatics received in randomised order single doses of pirbuterol (200 and 400 microgram), salbutamol (200 microgram) and placebo-aerosols, in order to determine the extent and duration of bronchodilator activity, the optimum dosage, the incidence, type and degree of side effects and the cardiovascular as well as hematologic, renal and hepatic functions after inhalative administration."5.04Comparative investigations on pirbuterol, salbutamol and placebo aerosols in bronchial asthma. ( Beumer, HM, 1979)
"In a single blind cross-over study 12 patients with asthma received in randomised order aerosols of pirbuterol 400 micrograms, salbutamol 200 micrograms or placebo."5.04[Comparative studies on pirbuterol, salbutamol and a placebo administered as an aerosol in asthmatic patients]. ( Verstraeten, JM, 1978)
"The acute pulmonary and cardiovascular effects of pirbuterol dihydrochloride 10 mg and 15 mg, a new orally active beta 2-selective sympathomimetic agent, were compared with those of placebo and metaproterenol 20 mg over a period of seven hours in 24 stable asthmatics."5.04Acute bronchial and cardiovascular effects of oral pirbuterol and metaproterenol. ( Child, JS; Ence, TJ; Ho, D; Tashkin, DP, 1979)
"This paper reviews the impact of the use of technologically dissimilar beta-agonist aerosols--the Maxair Autohaler (pirbuterol acetate) breath-actuated aerosol and the traditional albuterol press-and-breathe inhaler-on the treatment costs of asthma."3.70The technology of metered-dose inhalers and treatment costs in asthma: a retrospective study of breath actuation versus traditional press-and-breathe inhalers. ( Langley, PC, 1999)
"We studied the effects of an oral beta2 selective bronchodilator, pirbuterol, in 12 male asthmatic patients over periods ranging from 6 to 23 months (mean, 13."3.66Long-term oral bronchodilator therapy of asthma with pirbuterol. ( Burki, NK; Diamond, L, 1978)
"In a double-blind trial the effects on ventilatory function (FEV1), heart rate and blood pressure of oral pirbuterol and oral salbutamol in various single doses were studied in ten patients with chronic asthma."3.65Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics. ( Grant, IW; Pocock, SJ; Willey, RF, 1976)
" Our conclusion is that pirbuterol is at least as effective and safe under conditions of chronic administration to asthmatics as metaproterenol and therefore can be considered a suitable alternative for therapy."2.67Comparison of safety and efficacy of inhaled pirbuterol with metaproterenol. ( Brandon, ML; Grieco, M; Hudson, L; Rosenthal, RR; Spector, SL; Tashkin, D; Tinkelman, DG; Votteri, B, 1990)
"Pirbuterol is a beta-adrenoceptor agonist which differs structurally from salbutamol in the substitution of a pyridine ring for the benzene ring."2.37Pirbuterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible bronchospastic disease. ( Brogden, RN; Richards, DM, 1985)
" The characteristics of the oral route are easy usage, precise dosage and assured effects."1.27Oral beta 2-selective adrenergic bronchodilators. ( Daniotti, S; Dottorini, M; Grassi, V; Schiassi, M; Tantucci, C, 1986)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199021 (58.33)18.7374
1990's10 (27.78)18.2507
2000's4 (11.11)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bianchi, M1
Clavenna, A1
Bonati, M1
Willey, RF2
Grant, IW3
Pocock, SJ1
Weinberger, M1
Abu-Hasan, M1
Yaegashi, M1
Yalamanchili, VA1
Kaza, V1
Weedon, J1
Heurich, AE1
Akerman, MJ1
Bonniaud, P1
Favrolt, N1
Collet, E1
Dumas, JP1
Guilloux, L1
Pauli, G1
Camus, P1
Seed, MJ1
Agius, RM1
Crompton, GK1
Beumer, HM4
Viallat, JR1
Boutin, C1
Razzouk, H1
Aebischer, JC1
Benoit, RC1
Scherrer, M1
Taylor, CR1
Baird, JR1
Blackburn, KJ1
Cambridge, D1
Constantine, JW1
Ghaly, MS1
Hayden, ML1
McIlhenny, HM1
Moore, PF1
Olukotun, AY1
Pullman, LG1
Salsburg, DS1
Saxton, CA1
Shevde, S1
Littner, MR1
Tashkin, DP2
Calvarese, B1
Bautista, M1
Brandon, ML2
Schecker, MH1
Wilson, AF1
Mukai, DS1
Hahn, M2
Crook, D1
Novey, HS1
Tinkelman, DG3
Vanden Burgt, JA1
Ekholm, BP1
Bronsky, EA1
Debelic, M1
Pujet, JC1
Chinet, TC1
Silverman, R1
Sellers, J1
Greene, S1
Flaster, E1
Colice, G1
Langley, PC1
Kelloway, JS1
Wyatt, R1
Paterson, IC1
Verstraeten, JM1
Ence, TJ1
Ho, D1
Child, JS1
Burki, NK1
Diamond, L1
Lutz, C1
Völkl, KP1
Kroll, VM1
Wiesemann, HG1
Schneider, B1
Grieco, M1
Hudson, L1
Rosenthal, RR1
Spector, SL1
Tashkin, D1
Votteri, B1
Chodosh, S1
Crooks, LA1
Tuck, J1
Richards, DM1
Brogden, RN1
Ugriumova, MO1
Grassi, V1
Daniotti, S1
Schiassi, M1
Dottorini, M1
Tantucci, C1
Mattila, MJ1
Salonen, RO1
Ruotsalainen, EM1
Steen, SN1
Ziment, I1
Thomas, JS1

Reviews

4 reviews available for pirbuterol and Asthma, Bronchial

ArticleYear
Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period.
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:9

    Topics: Acetates; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bude

2010
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
    American heart journal, 1981, Volume: 102, Issue:3 Pt 2

    Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Dr

1981
Pirbuterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible bronchospastic disease.
    Drugs, 1985, Volume: 30, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Asthma; Biotransformation; Bronchial Spasm; Bronchodilator Agents

1985
[State of the adrenoreceptor system and drug therapy].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Asthma; Dobutamine; Ethanolamines; Humans; Mice; Propranolol; Rat

1985

Trials

21 trials available for pirbuterol and Asthma, Bronchial

ArticleYear
Pirbuterol.
    Lancet (London, England), 1984, Apr-07, Volume: 1, Issue:8380

    Topics: Albuterol; Animals; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Et

1984
Pirbuterol versus orciprenaline aerosols in the treatment of bronchial asthma.
    International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:3

    Topics: Adult; Aerosols; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Clinical Trials as Topic; Doub

1983
Pirbuterol syrup--treatment of asthma in children in a residential asthma clinic.
    The British journal of clinical practice, 1984, Volume: 38, Issue:10

    Topics: Asthma; Child; Clinical Trials as Topic; Ethanolamines; Female; Humans; Male; Respiratory Function T

1984
[Pirbuterol and salbutamol aerosol for exercise-induced bronchoconstriction].
    Schweizerische medizinische Wochenschrift, 1984, Nov-17, Volume: 114, Issue:46

    Topics: Adult; Aerosols; Albuterol; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Ethanolamines;

1984
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
    American heart journal, 1981, Volume: 102, Issue:3 Pt 2

    Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Dr

1981
Acute bronchial and cardiovascular effects of increasing doses of pirbuterol acetate aerosol in asthma.
    Annals of allergy, 1982, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Blood Pressure; Bronchi; Bronchodilator Agents; Cardiovas

1982
A device for overcoming discoordination with metered-dose inhalers.
    The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:6

    Topics: Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Ethanolamines; Female; Forced Expiratory Vol

1993
Double-blind, clinical efficacy study comparing 400 micrograms of pirbuterol versus placebo delivered by a breath-actuated aerosol inhaler.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1994, Volume: 31, Issue:3

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Double-Blind Method

1994
Comparison of the Maxair Autohaler to wet nebulizer in patients with acute asthma.
    Chest, 1998, Volume: 114, Issue:3

    Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchodilator Agents

1998
A cost-effectiveness analysis of breath-actuated metered-dose inhalers.
    Managed care interface, 1997, Volume: 10, Issue:9

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Child; Cost-B

1997
Effects of prolonged administration of pirbuterol by mouth in chronic asthma.
    British journal of clinical pharmacology, 1977, Volume: 4, Issue:3

    Topics: Administration, Oral; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Chronic Disease; Cl

1977
Pirbuterol in the treatment of bronchial asthma.
    International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Clinical Trials as Topic; Et

1979
Comparative investigations on pirbuterol, salbutamol and placebo aerosols in bronchial asthma.
    International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aerosols; Aged; Albuterol; Asthma; Bronchodilator Agents; Clinical Trials as Topi

1979
[Comparative studies on pirbuterol, salbutamol and a placebo administered as an aerosol in asthmatic patients].
    Revue de l'Institut d'hygiene des mines, 1978, Volume: 33, Issue:4

    Topics: Adult; Aerosols; Aged; Albuterol; Asthma; Bronchodilator Agents; Ethanolamines; Evaluation Studies a

1978
Acute bronchial and cardiovascular effects of oral pirbuterol and metaproterenol.
    Annals of allergy, 1979, Volume: 43, Issue:4

    Topics: Acute Disease; Adult; Aged; Airway Obstruction; Asthma; Bronchodilator Agents; Cardiovascular System

1979
Effect of increasing dosage of an inhaled beta-2 specific agonist on pulmonary function, tremor, and cardiovascular indices.
    Annals of allergy, 1992, Volume: 68, Issue:1

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Ethanolamines; Hemodynam

1992
Clinical efficacy of two beta 2-sympathicomimetics in different inhalers in children with asthma. Comparison of pirbuterol in a breath-actuated inhaler and salbutamol in a customary metered-dose inhaler.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:5

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Asthma; Child; Ethanolamines; Femal

1991
Comparison of safety and efficacy of inhaled pirbuterol with metaproterenol.
    Annals of allergy, 1990, Volume: 64, Issue:2 Pt 2

    Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Double

1990
Comparative effects of pirbuterol acetate, metaproterenol, and placebo aerosols on pulmonary function and incidence of cardiac ectopy.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1989, Volume: 26, Issue:5

    Topics: Adult; Aerosols; Aged; Asthma; Bronchitis; Bronchodilator Agents; Cardiac Complexes, Premature; Elec

1989
Bronchodilator combinations in animals and in man.
    Annals of clinical research, 1985, Volume: 17, Issue:3

    Topics: Adult; Animals; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Drug C

1985
Pyrbuterol: a new bronchodilator. Phase I-single dose study.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:10

    Topics: Adult; Aged; Airway Resistance; Asthma; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Buty

1974

Other Studies

12 other studies available for pirbuterol and Asthma, Bronchial

ArticleYear
Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:4

    Topics: Administration, Oral; Aged; Albuterol; Asthma; Blood Pressure; Bronchodilator Agents; Dose-Response

1976
Life-threatening asthma during treatment with salmeterol.
    The New England journal of medicine, 2006, Aug-24, Volume: 355, Issue:8

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Albuterol; Androstadienes; Asthma;

2006
The utility of the forced oscillation technique in assessing bronchodilator responsiveness in patients with asthma.
    Respiratory medicine, 2007, Volume: 101, Issue:5

    Topics: Adult; Airway Resistance; Anthropometry; Asthma; Bronchodilator Agents; Ethanolamines; Female; Force

2007
Salbutamol, terbutaline and pirbuterol allergy in an asthmatic patient.
    Allergy, 2007, Volume: 62, Issue:10

    Topics: Adult; Aerosols; Albuterol; Asthma; Bronchoconstriction; Bronchodilator Agents; Drug Hypersensitivit

2007
Paradoxical asthma hazard of short-acting beta2-agonists.
    Allergy, 2008, Volume: 63, Issue:2

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchoconstrictio

2008
Long-term treatment of bronchial asthma with pirbuterol aerosol.
    International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:4

    Topics: Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Ethanolamines; Humans; Lung; Middle Aged

1983
Pirbuterol vs. hydroxyzine vs. theophylline vs. placebo in the treatment of bronchial asthma.
    Annals of allergy, 1980, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Asthma; Blood Pressure; Double-Blind Method; Ethanolamines; Female; Forced Expira

1980
Ease-of-use study of pirbuterol acetate in the Autohaler actuator in three countries: the United States, Germany, and France.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1993, Volume: 30, Issue:6

    Topics: Adult; Asthma; Bronchodilator Agents; Ethanolamines; Evaluation Studies as Topic; Female; France; Ge

1993
Management of chronic obstructive pulmonary disease.
    The New England journal of medicine, 1993, Sep-23, Volume: 329, Issue:13

    Topics: Albuterol; Asthma; Bronchodilator Agents; Ethanolamines; Humans

1993
The technology of metered-dose inhalers and treatment costs in asthma: a retrospective study of breath actuation versus traditional press-and-breathe inhalers.
    Clinical therapeutics, 1999, Volume: 21, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator Agents; Cost Savings; Costs and Cost Ana

1999
Long-term oral bronchodilator therapy of asthma with pirbuterol.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:1

    Topics: Administration, Oral; Adult; Aged; Asthma; Bronchodilator Agents; Ethanolamines; Humans; Male; Middl

1978
Oral beta 2-selective adrenergic bronchodilators.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Administration, Oral; Adrenergic beta-Agonists; Aged; Asthma; Bronchodilator Agents; Child; Clenbute

1986