pirarubicin and Spinal-Neoplasms

pirarubicin has been researched along with Spinal-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for pirarubicin and Spinal-Neoplasms

Article	Year
Selective intra-arterial chemoembolization of pelvic and spine bone metastases. European radiology, 2004, Volume: 14, Issue:10 The purpose of this study was to determine the effect of interventional palliative therapy by using chemoembolization on metastatic bone pain and tumor bulk in inoperable metastases where chemotherapy and radiotherapy had failed. Twenty-five patients (mean age: 59 years) underwent chemoembolization of symptomatic lytic lesions involving the spinal column (n=10), iliac bone and sacrum (n=15). The study design consisted of at least three procedures based on combined chemoembolization performed under analog-sedation. Therapeutic agents were carboplatin for selective chemotherapy and pirarubicin mixed with polyvinyl alcohol foam for chemoembolization. Fifteen of 18 (83%) patients had significant pain relief, as shown by the decrease of analgesic drug use. Mean clinical response duration was 12 months. Radiologically, ten patients were stable. A partial response was observed in four patients, while a complete response was seen in two others. Selective intra-arterial chemoembolization gives longer pain relief than embolization, compared to the literature data, probably because of partial response with local anti-cancer drugs. Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Chemoembolization, Therapeutic; Doxorubicin; Female; Follow-Up Studies; Humans; Ilium; Infusions, Intra-Arterial; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Palliative Care; Pelvic Bones; Polyvinyl Alcohol; Sacrum; Spinal Neoplasms; Thoracic Vertebrae	2004
[A case of sacral neuroblastoma in an adult successfully treated with combination chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:8 A 35-year-old woman was admitted with complaints of severe posterior femoral pain and was diagnosed as having sacral neuroblastoma by tumor open biopsy. After admission, combination chemotherapy consisting of CDDP, etoposide, CPA, and THP was started intra-arterially and intravenously. After 2 courses of chemotherapy, her symptoms markedly improved and the tumor size was reduced. Now, after completion of 16 courses of chemotherapy, she is in a state of partial remission. Hereafter, we intend to reconsider the treatment strategy including surgical therapy. Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Neuroblastoma; Sacrum; Spinal Neoplasms	1995

Article

Year

Selective intra-arterial chemoembolization of pelvic and spine bone metastases.

European radiology, 2004, Volume: 14, Issue:10

The purpose of this study was to determine the effect of interventional palliative therapy by using chemoembolization on metastatic bone pain and tumor bulk in inoperable metastases where chemotherapy and radiotherapy had failed. Twenty-five patients (mean age: 59 years) underwent chemoembolization of symptomatic lytic lesions involving the spinal column (n=10), iliac bone and sacrum (n=15). The study design consisted of at least three procedures based on combined chemoembolization performed under analog-sedation. Therapeutic agents were carboplatin for selective chemotherapy and pirarubicin mixed with polyvinyl alcohol foam for chemoembolization. Fifteen of 18 (83%) patients had significant pain relief, as shown by the decrease of analgesic drug use. Mean clinical response duration was 12 months. Radiologically, ten patients were stable. A partial response was observed in four patients, while a complete response was seen in two others. Selective intra-arterial chemoembolization gives longer pain relief than embolization, compared to the literature data, probably because of partial response with local anti-cancer drugs.

Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Chemoembolization, Therapeutic; Doxorubicin; Female; Follow-Up Studies; Humans; Ilium; Infusions, Intra-Arterial; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Palliative Care; Pelvic Bones; Polyvinyl Alcohol; Sacrum; Spinal Neoplasms; Thoracic Vertebrae

2004

[A case of sacral neuroblastoma in an adult successfully treated with combination chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:8

A 35-year-old woman was admitted with complaints of severe posterior femoral pain and was diagnosed as having sacral neuroblastoma by tumor open biopsy. After admission, combination chemotherapy consisting of CDDP, etoposide, CPA, and THP was started intra-arterially and intravenously. After 2 courses of chemotherapy, her symptoms markedly improved and the tumor size was reduced. Now, after completion of 16 courses of chemotherapy, she is in a state of partial remission. Hereafter, we intend to reconsider the treatment strategy including surgical therapy.

Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Neuroblastoma; Sacrum; Spinal Neoplasms

1995