pirarubicin and Paralysis

pirarubicin has been researched along with Paralysis* in 1 studies

Other Studies

1 other study(ies) available for pirarubicin and Paralysis

ArticleYear
[Sciatic nerve paralysis following intraarterial chemotherapy for bladder cancer: reports of two cases].
    Hinyokika kiyo. Acta urologica Japonica, 1993, Volume: 39, Issue:8

    Bilateral sciatic nerve paralysis developed in two patients with invasive bladder cancer following intraarterial infusion of cisplatin (CDDP) and 4'-0-tetrahydropyranyladriamycin (THP) as preoperative adjuvant chemotherapy. Balloon catheters were selectively inserted into both internal iliac arteries, and CDDP 100 mg/m2 and THP 40 mg/m2 were administered under balloon occlusion. Pain of lower extremities developed soon after infusion and was gradually followed by paralysis. One patient recovered from paralysis partially after 4 months, but the other patient didn't recover. The use of balloon catheters resulted in an excessive concentration of chemotherapeutic agents with the adverse action on the sciatic nerves.

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Paralysis; Peripheral Nervous System Diseases; Sciatic Nerve; Urinary Bladder Neoplasms

1993