pirarubicin and Chickenpox

Angioimmunoblastic T-cell lymphoma (AITL) is a rare subtype of peripheral T-cell lymphoma that causes immunological disorders such as immunosuppression, autoimmune disease-like symptoms and allergy. We report a case of a 67-year-old man with AITL who had a serious varicella zoster virus (VZV) reinfection that appeared clinically to be varicella. Forty percent of cases of AITL are associated with skin rash. A variety of cutaneous manifestations have been reported; however, the majority are macropapular eruptions that are often diagnosed as drug associated. Our study emphasizes the need to correctly diagnose opportunistic infections, such as the varicella that is documented in our patient, at early stages in AITL.

Topics: Acyclovir; Aged; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Chickenpox; Cyclophosphamide; Diagnosis, Differential; Doxorubicin; Herpesvirus 3, Human; Humans; Immunocompromised Host; Infusions, Intravenous; Lymphoma, T-Cell; Male; Prednisone; Recurrence; Vincristine