Page last updated: 2024-11-02

piracetam and Tourette Syndrome

piracetam has been researched along with Tourette Syndrome in 6 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)

Research Excerpts

ExcerptRelevanceReference
"To evaluate the usefulness of levetiracetam (LEV) for the treatment of tics in patients with Tourette syndrome (TS) by means of a prospective, open-label, 12-week study."9.14An open-label, prospective study of levetiracetam in children and adolescents with Tourette syndrome. ( Calleja-Pérez, B; Fernández-Jaén, A; Fernández-Mayoralas, DM; Muñoz-Jareño, N, 2009)
"We compared the efficacy of clonidine and levetiracetam for treating tics in Tourette syndrome."9.14Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome. ( Hedderick, EF; Morris, CM; Singer, HS, 2009)
"The objective of this study was to investigate the effectiveness of levetiracetam for the treatment of tics in children with Tourette syndrome (TS)."9.12A double blind randomized placebo control trial of levetiracetam in Tourette syndrome. ( Bridges, DD; Paynter, NP; Singer, HS; Smith-Hicks, CL, 2007)
"Levetiracetam, an anti-epileptic agent that enhances GABAergic neurotransmission, is one of the newest alternative treatments of Tourette syndrome (TS)."7.74Levetiracetam in the treatment of antipsychotics-resistant Tourette syndrome. ( Karakatsanis, NA; Karapoulios, E; Kouzoupis, AV; Masdrakis, VG; Oulis, P; Papadimitriou, GN; Papageorgiou, C; Soldatos, CR, 2008)
"Levetiracetam is an antiepileptic drug with atypical mechanisms of action that might be beneficial for this indication."6.71Use of levetiracetam to treat tics in children and adolescents with Tourette syndrome. ( Awaad, Y; Michon, AM; Minarik, S, 2005)
"To evaluate the usefulness of levetiracetam (LEV) for the treatment of tics in patients with Tourette syndrome (TS) by means of a prospective, open-label, 12-week study."5.14An open-label, prospective study of levetiracetam in children and adolescents with Tourette syndrome. ( Calleja-Pérez, B; Fernández-Jaén, A; Fernández-Mayoralas, DM; Muñoz-Jareño, N, 2009)
"We compared the efficacy of clonidine and levetiracetam for treating tics in Tourette syndrome."5.14Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome. ( Hedderick, EF; Morris, CM; Singer, HS, 2009)
"The objective of this study was to investigate the effectiveness of levetiracetam for the treatment of tics in children with Tourette syndrome (TS)."5.12A double blind randomized placebo control trial of levetiracetam in Tourette syndrome. ( Bridges, DD; Paynter, NP; Singer, HS; Smith-Hicks, CL, 2007)
"Levetiracetam, an anti-epileptic agent that enhances GABAergic neurotransmission, is one of the newest alternative treatments of Tourette syndrome (TS)."3.74Levetiracetam in the treatment of antipsychotics-resistant Tourette syndrome. ( Karakatsanis, NA; Karapoulios, E; Kouzoupis, AV; Masdrakis, VG; Oulis, P; Papadimitriou, GN; Papageorgiou, C; Soldatos, CR, 2008)
"Levetiracetam is an antiepileptic drug with atypical mechanisms of action that might be beneficial for this indication."2.71Use of levetiracetam to treat tics in children and adolescents with Tourette syndrome. ( Awaad, Y; Michon, AM; Minarik, S, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fernández-Jaén, A1
Fernández-Mayoralas, DM1
Muñoz-Jareño, N1
Calleja-Pérez, B1
Hedderick, EF1
Morris, CM1
Singer, HS2
Jiménez-Genchi, A1
Ávila-Ordóñez, MU1
Félix-Orta, F1
Ballesteros-Montero, AT1
Awaad, Y1
Michon, AM1
Minarik, S1
Smith-Hicks, CL1
Bridges, DD1
Paynter, NP1
Oulis, P1
Karapoulios, E1
Masdrakis, VG1
Kouzoupis, AV1
Karakatsanis, NA1
Papageorgiou, C1
Papadimitriou, GN1
Soldatos, CR1

Trials

4 trials available for piracetam and Tourette Syndrome

ArticleYear
An open-label, prospective study of levetiracetam in children and adolescents with Tourette syndrome.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2009, Volume: 13, Issue:6

    Topics: Adolescent; Child; Dose-Response Relationship, Drug; Female; Humans; Levetiracetam; Male; Nootropic

2009
Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome.
    Pediatric neurology, 2009, Volume: 40, Issue:6

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Child; Clonidine; Confidence Intervals; Cross-Sectiona

2009
Use of levetiracetam to treat tics in children and adolescents with Tourette syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:6

    Topics: Adolescent; Anticonvulsants; Child; Demography; Dose-Response Relationship, Drug; Educational Status

2005
A double blind randomized placebo control trial of levetiracetam in Tourette syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 2007, Sep-15, Volume: 22, Issue:12

    Topics: Adolescent; Anticonvulsants; Child; Confidence Intervals; Dose-Response Relationship, Drug; Double-B

2007

Other Studies

2 other studies available for piracetam and Tourette Syndrome

ArticleYear
[Frontal lobe nocturnal epilepsy in an adult with Gilles de la Tourette syndrome].
    Revista de neurologia, 2011, Oct-01, Volume: 53, Issue:7

    Topics: Adult; Anticonvulsants; Epilepsy, Frontal Lobe; Humans; Levetiracetam; Male; Piracetam; Polysomnogra

2011
Levetiracetam in the treatment of antipsychotics-resistant Tourette syndrome.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2008, Volume: 9, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Anti-Dyskinesia Agents; Anticonvulsants; Antipsychotic Agents; Clo

2008