Page last updated: 2024-11-02

piracetam and Spasms, Infantile

piracetam has been researched along with Spasms, Infantile in 11 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)

Research Excerpts

ExcerptRelevanceReference
"With the diagnosis of Lennox-Gastaut syndrome the patient was treated with levetiracetam, showing a substantial improvement in the cognitive sphere, in the control of seizures, and electroencephalographic findings."7.77Levetiracetam efficacy in patients with Lennox-Gastaut syndrome. Presentation of a case. ( Carneado Ruiz, J; Díaz Negrillo, A; González Salaices, M; Martín Del Valle, F; Prieto Jurczynska, C, 2011)
" The point estimates of carbamazepine and lamotrigine efficacy showed their superiority with respect to all comparator antiepileptic drugs for the treatment of newly diagnosed focal epilepsy."4.98Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis. ( Crescioli, G; De Masi, S; Guerrini, R; Ilvento, L; Lucenteforte, E; McGreevy, KS; Mugelli, A; Pugi, A; Rosati, A; Virgili, G, 2018)
"With the diagnosis of Lennox-Gastaut syndrome the patient was treated with levetiracetam, showing a substantial improvement in the cognitive sphere, in the control of seizures, and electroencephalographic findings."3.77Levetiracetam efficacy in patients with Lennox-Gastaut syndrome. Presentation of a case. ( Carneado Ruiz, J; Díaz Negrillo, A; González Salaices, M; Martín Del Valle, F; Prieto Jurczynska, C, 2011)
"West syndrome is an age-dependent epilepsy with onset peak in the first year of life whose aetiology may be symptomatic or cryptogenic."1.39West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence? ( Fontana, A; Giordano, G; Mangano, GR; Mangano, S; Nardello, R; Spitaleri, C; Tripi, G, 2013)
"The infantile spasms were resistant to treatment with clobazam."1.33Levetiracetam in the treatment of infantile spasms. ( Devlin, AM; Lawlor, KM, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's8 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosati, A1
Ilvento, L1
Lucenteforte, E1
Pugi, A1
Crescioli, G1
McGreevy, KS1
Virgili, G1
Mugelli, A1
De Masi, S1
Guerrini, R1
Mahmoud, AA1
Rizk, TM1
Mansy, AA1
Ali, JA1
Al-Tannir, MA1
Mangano, S1
Nardello, R1
Tripi, G1
Giordano, G1
Spitaleri, C1
Mangano, GR1
Fontana, A1
Okumura, A1
Arai, E1
Kitamura, Y1
Abe, S1
Ikeno, M1
Fujimaki, T1
Yamamoto, T1
Shimizu, T1
Singh, D1
Lau, M1
Ayers, T1
Singh, Y1
Akingbola, O1
Barbiero, L1
Nelson, S1
Díaz Negrillo, A1
Martín Del Valle, F1
González Salaices, M1
Prieto Jurczynska, C1
Carneado Ruiz, J1
Koppelstäetter, A1
Bührer, C1
Kaindl, AM1
Isoda, K1
Tomoyasu, C1
Fujii, N1
Nishimura, A1
Lawlor, KM1
Devlin, AM1
Gümüş, H1
Kumandaş, S1
Per, H1
Mikati, MA1
El Banna, D1
Sinno, D1
Mroueh, S1

Reviews

1 review available for piracetam and Spasms, Infantile

ArticleYear
Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis.
    Epilepsia, 2018, Volume: 59, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Ch

2018

Trials

3 trials available for piracetam and Spasms, Infantile

ArticleYear
Ineffectiveness of topiramate and levetiracetam in infantile spasms non-responsive to steroids. Open labeled randomized prospective study.
    Neurosciences (Riyadh, Saudi Arabia), 2013, Volume: 18, Issue:2

    Topics: Anticonvulsants; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female

2013
Levetiracetam monotherapy in newly diagnosed cryptogenic West syndrome.
    Pediatric neurology, 2007, Volume: 37, Issue:5

    Topics: Anticonvulsants; Female; Humans; Infant; Levetiracetam; Male; Piracetam; Retrospective Studies; Spas

2007
Response of infantile spasms to levetiracetam.
    Neurology, 2008, Feb-12, Volume: 70, Issue:7

    Topics: Anticonvulsants; Body Weight; Brain; Deglutition Disorders; Dose-Response Relationship, Drug; Drug A

2008

Other Studies

7 other studies available for piracetam and Spasms, Infantile

ArticleYear
West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence?
    BMC neurology, 2013, May-24, Volume: 13

    Topics: Adolescent; Brain; Disease Progression; Humans; Infant; Levetiracetam; Magnetic Resonance Imaging; M

2013
Epilepsy phenotypes in siblings with Norrie disease.
    Brain & development, 2015, Volume: 37, Issue:10

    Topics: Anticonvulsants; Blindness; Chromosomes, Human, X; Electroencephalography; Epilepsy; Eye Proteins; G

2015
De Novo Heterogeneous Mutations in SCN2A and GRIN2A Genes and Seizures With Ictal Vocalizations.
    Clinical pediatrics, 2016, Volume: 55, Issue:9

    Topics: Anticonvulsants; Clonazepam; Diagnosis, Differential; Electroencephalography; Female; Fructose; Huma

2016
Levetiracetam efficacy in patients with Lennox-Gastaut syndrome. Presentation of a case.
    Neurologia (Barcelona, Spain), 2011, Volume: 26, Issue:5

    Topics: Anticonvulsants; Child, Preschool; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Levetir

2011
[Treating Neonates with Levetiracetam: a survey among German University Hospitals].
    Klinische Padiatrie, 2011, Volume: 223, Issue:7

    Topics: Anticonvulsants; Drug Utilization; Germany; Health Surveys; Hospitals, University; Humans; Infant, N

2011
[Levetiracetam-induced aggravation to non-convulsive status epilepticus in a boy with Lennox-Gastaut syndrome].
    No to hattatsu = Brain and development, 2012, Volume: 44, Issue:5

    Topics: Anticonvulsants; Child; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Levetiracetam; Mal

2012
Levetiracetam in the treatment of infantile spasms.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2005, Volume: 9, Issue:1

    Topics: Anticonvulsants; Electroencephalography; Humans; Infant; Levetiracetam; Male; Piracetam; Spasms, Inf

2005