Page last updated: 2024-11-02

piracetam and Schizophrenia

piracetam has been researched along with Schizophrenia in 13 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Treatment with levetiracetam dose-dependently improved memory performance of the ketamine-exposed rats."5.48Treatment with levetiracetam improves cognition in a ketamine rat model of schizophrenia. ( Gallagher, M; Koh, MT; Rosenzweig-Lipson, S; Shao, Y, 2018)
"A study of 246 patients (with schizophrenia, manic depressive psychoses and psychoorganic syndrome) treated by some drugs of a metabolic action (encephalotropic", "nootropic" drugs, piracetam, piriditol and pantogam) permitted one to determine the place of these preparations in a comprehensive treatment of mental disorders."3.66[Certain principles for differential utilization of metabolic treatment preparations in the complex therapy of mental disorders]. ( AvrutskiÄ­, GIa; Laskova, NB, 1979)
"Piracetam is a potent antioxidant, a cerebral neuroprotector, a neuronal metabolic enhancer, and a brain integrative agent."2.73Efficacy of piracetam in the treatment of tardive dyskinesia in schizophrenic patients: a randomized, double-blind, placebo-controlled crossover study. ( Bersudsky, Y; Dwolatzky, T; Lerner, V; Libov, I; Miodownik, C, 2007)
" Daily dosage of piracetam was 7."2.70Effect of piracetam on ECT-induced cognitive disturbances: a randomized, placebo-controlled, double-blind study. ( Leung, HC; Tang, WK; Ungvari, GS, 2002)
" All patients were kept on continuous psychotropic medication for at least 3 weeks before starting the trial, and piracetam was given additionally in a fixed dosage of 2400 mg daily; the same number of identical capsules was given during the pre- and post-treatment placebo periods."2.65Biological correlates of piracetam clinical effects in psychotic patients. ( Erban, L; Hanzlicek, L; Kabes, J; Skondia, V, 1979)
"Treatment with levetiracetam dose-dependently improved memory performance of the ketamine-exposed rats."1.48Treatment with levetiracetam improves cognition in a ketamine rat model of schizophrenia. ( Gallagher, M; Koh, MT; Rosenzweig-Lipson, S; Shao, Y, 2018)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koh, MT1
Shao, Y1
Rosenzweig-Lipson, S1
Gallagher, M1
Lerner, V2
Miodownik, C2
Tang, WK1
Ungvari, GS1
Leung, HC1
Libov, I1
Bersudsky, Y1
Dwolatzky, T1
Noorbala, AA1
Akhondzadeh, S1
Davari-Ashtiani, R1
Amini-Nooshabadi, H1
Fehr, C1
Dahmen, N1
Klawe, C1
Eicke, M1
Szegedi, A1
Dimond, SJ1
Scammell, RE1
Pryce, IG3
Huws, D1
Gray, C2
AvrutskiÄ­, GIa1
Laskova, NB1
Kabes, J1
Erban, L1
Hanzlicek, L1
Skondia, V1
Tacke, B1
Freistein, H1
Kempf, H1
Windheuser, A1
Wilsher, CR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Therapeutic Use of Piracetam for Treatment of Patients Suffering From Tardive Dyskinesia: a Double Blind, Placebo-Controlled Crossover Study[NCT00190008]Phase 340 participants Interventional2003-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for piracetam and Schizophrenia

ArticleYear
Motor symptoms of schizophrenia: is tardive dyskinesia a symptom or side effect? A modern treatment.
    Current psychiatry reports, 2011, Volume: 13, Issue:4

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Fatty Acids, Omega-3; Ginkgo biloba; Humans; Levetira

2011
Effects of piracetam on developmental dyslexia.
    International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 1986, Volume: 4, Issue:1

    Topics: Animals; Cerebral Cortex; Clinical Trials as Topic; Conditioning, Operant; Corpus Callosum; Dogs; Do

1986

Trials

8 trials available for piracetam and Schizophrenia

ArticleYear
Effect of piracetam on ECT-induced cognitive disturbances: a randomized, placebo-controlled, double-blind study.
    The journal of ECT, 2002, Volume: 18, Issue:3

    Topics: Adult; Depression; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Male; Memory Diso

2002
Efficacy of piracetam in the treatment of tardive dyskinesia in schizophrenic patients: a randomized, double-blind, placebo-controlled crossover study.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:7

    Topics: Administration, Oral; Adult; Aged; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug-Induced

2007
Piracetam in the treatment of schizophrenia: implications for the glutamate hypothesis of schizophrenia.
    Journal of clinical pharmacy and therapeutics, 1999, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Co

1999
Some effects of piracetam (UCB 6215, Nootropyl) on chronic schizophrenia.
    Psychopharmacology, 1979, Volume: 64, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Dichotic Listening Tests; Double-Blind Method; Fem

1979
Trial of 'Piracetam' in chronic schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1978, Volume: 132

    Topics: Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Humans; Piracetam; Pyrrolidinones; S

1978
Biological correlates of piracetam clinical effects in psychotic patients.
    The Journal of international medical research, 1979, Volume: 7, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Depression; Drug Therapy, Combination; Energy

1979
[Pilot study of 2-pyrrolidon-acetamid (generic name: piracetam) (author's transl)].
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1975, Volume: 8, Issue:2

    Topics: Adult; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Drug Evaluation; Humans; Middle Aged

1975
Effects of piracetam on developmental dyslexia.
    International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 1986, Volume: 4, Issue:1

    Topics: Animals; Cerebral Cortex; Clinical Trials as Topic; Conditioning, Operant; Corpus Callosum; Dogs; Do

1986

Other Studies

4 other studies available for piracetam and Schizophrenia

ArticleYear
Treatment with levetiracetam improves cognition in a ketamine rat model of schizophrenia.
    Schizophrenia research, 2018, Volume: 193

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cognition Disorders; Disease Models, Animal

2018
Piracetam in the treatment of tardive dyskinesia and akathisia: a case report.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Dyskinesia, Drug-Induced; Haloperidol; Humans;

2001
[Certain principles for differential utilization of metabolic treatment preparations in the complex therapy of mental disorders].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:8

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Brain Injuries; gamma-Aminobutyric Acid; Humans; Infectio

1979
Clinical research upon mentally ill subjects who cannot give informed consent.
    The British journal of psychiatry : the journal of mental science, 1978, Volume: 133

    Topics: Ethics, Medical; Human Experimentation; Humans; Informed Consent; Mental Disorders; Piracetam; Resea

1978