Page last updated: 2024-11-02

piracetam and Neuralgia

piracetam has been researched along with Neuralgia in 11 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Levetiracetam is an anticonvulsant which is assumed to act by modulating neurotransmitter release via binding to the vesicle protein SV2A."6.77A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis. ( Falah, M; Holbech, JV; Madsen, C; Sindrup, SH, 2012)
"Central neuropathic pain (CNP) is a prevalent and distressing symptom in patients with multiple sclerosis (MS)."6.74Effects of levetiracetam on chronic pain in multiple sclerosis: results of a pilot, randomized, placebo-controlled study. ( Bernardi, G; Buttari, F; Castelli, M; Centonze, D; Codecà, C; Fiore, S; Mataluni, G; Musella, A; Rossi, S, 2009)
"Levetiracetam is an anticonvulsant which is assumed to act by modulating neurotransmitter release via binding to the vesicle protein SV2A."2.77A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis. ( Falah, M; Holbech, JV; Madsen, C; Sindrup, SH, 2012)
"Levetiracetam is an anticonvulsant which is assumed to act by modulating neurotransmitter release via binding to the vesicle protein SV2A."2.76The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trial. ( Bach, FW; Holbech, JV; Jensen, TS; Otto, M; Sindrup, SH, 2011)
"Central neuropathic pain (CNP) is a prevalent and distressing symptom in patients with multiple sclerosis (MS)."2.74Effects of levetiracetam on chronic pain in multiple sclerosis: results of a pilot, randomized, placebo-controlled study. ( Bernardi, G; Buttari, F; Castelli, M; Centonze, D; Codecà, C; Fiore, S; Mataluni, G; Musella, A; Rossi, S, 2009)
"Levetiracetam is a new antiepileptic drug."2.72Specific effect of levetiracetam in experimental human pain models. ( Enggaard, TP; Klitgaard, NA; Sindrup, SH, 2006)
"Piracetam is a prototype of nootropic drugs, used to improve cognitive impairment."1.40Analgesic effect of piracetam on peripheral neuropathic pain induced by chronic constriction injury of sciatic nerve in rats. ( Bhati, Y; Mehta, AK; Sharma, KK; Tripathi, CD, 2014)
"Levetiracetam is a state of the art antiepileptic drug that has displayed antinociceptive activity in experimental models of pain and clinical effectiveness as an analgesic in series of patients with neuropathic pain."1.37[The effectiveness of levetiracetam in the treatment of neuropathic pain]. ( Del Pozo, E; González-Contreras, LG; Pereira-Pérez, E, 2011)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mehta, AK1
Bhati, Y1
Tripathi, CD1
Sharma, KK1
Wiffen, PJ1
Derry, S1
Moore, RA1
Lunn, MP1
Crawford-Faucher, A1
Huijon, RM1
Vilholm, OJ1
Cold, S1
Rasmussen, L1
Sindrup, SH4
Rossi, S1
Mataluni, G1
Codecà, C1
Fiore, S1
Buttari, F1
Musella, A1
Castelli, M1
Bernardi, G1
Centonze, D1
Holbech, JV2
Otto, M1
Bach, FW1
Jensen, TS1
Del Pozo, E1
Pereira-Pérez, E1
González-Contreras, LG1
Falah, M1
Madsen, C1
Jungehulsing, GJ1
Israel, H1
Safar, N1
Taskin, B1
Nolte, CH1
Brunecker, P1
Wernecke, KD1
Villringer, A1
Rowbotham, MC1
Manville, NS1
Ren, J1
Enggaard, TP1
Klitgaard, NA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Placebo-Controlled Crossover Trial of Levetiracetam on Ethanol Intake[NCT01168687]46 participants (Actual)Interventional2008-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Standard Alcoholic Drinks Per Treatment Period

The primary outcome of this study is to determine the effect of levetiracetam on alcohol consumption as measured by change in # of drinks during each treatment period. (NCT01168687)
Timeframe: During each 14 day treatment period

Interventionnumber of drinks per treatment period (Mean)
All Subjects (n = 46) Placebo41.2
All Subjects (n = 46) Levetiracetam45.4

Reviews

1 review available for piracetam and Neuralgia

ArticleYear
Levetiracetam for neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2014, Jul-07, Issue:7

    Topics: Adult; Analgesics; Chronic Disease; Humans; Levetiracetam; Neuralgia; Piracetam; Randomized Controll

2014

Trials

7 trials available for piracetam and Neuralgia

ArticleYear
Effect of levetiracetam on the postmastectomy pain syndrome.
    European journal of neurology, 2008, Volume: 15, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Double-Blind Method; Female; Humans; Levetiracetam; Mast

2008
Effects of levetiracetam on chronic pain in multiple sclerosis: results of a pilot, randomized, placebo-controlled study.
    European journal of neurology, 2009, Volume: 16, Issue:3

    Topics: Adult; Analgesics; Anticonvulsants; Depression; Disability Evaluation; Female; Humans; Levetiracetam

2009
The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trial.
    European journal of pain (London, England), 2011, Volume: 15, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Cross-Over Studies; Double-Blind Method; Female; Humans; Levetiracetam

2011
A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis.
    European journal of pain (London, England), 2012, Volume: 16, Issue:6

    Topics: Adult; Analgesics; Anticonvulsants; Chronic Pain; Cross-Over Studies; Female; Humans; Hyperalgesia;

2012
Levetiracetam in patients with central neuropathic post-stroke pain--a randomized, double-blind, placebo-controlled trial.
    European journal of neurology, 2013, Volume: 20, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Cross-Over Studies; Double-Blind Method; Female; Humans; Levetiracetam

2013
Pilot tolerability and effectiveness study of levetiracetam for postherpetic neuralgia.
    Neurology, 2003, Sep-23, Volume: 61, Issue:6

    Topics: Analgesics, Non-Narcotic; Calcium Channel Blockers; Fatigue; Female; Herpes Zoster; Humans; Levetira

2003
Specific effect of levetiracetam in experimental human pain models.
    European journal of pain (London, England), 2006, Volume: 10, Issue:3

    Topics: Adult; Anticonvulsants; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Human

2006

Other Studies

3 other studies available for piracetam and Neuralgia

ArticleYear
Analgesic effect of piracetam on peripheral neuropathic pain induced by chronic constriction injury of sciatic nerve in rats.
    Neurochemical research, 2014, Volume: 39, Issue:8

    Topics: Analgesics; Animals; Male; Neuralgia; Pain Measurement; Piracetam; Rats; Rats, Wistar; Sciatic Neuro

2014
The Role of Levetiracetam in Treating Chronic Neuropathic Pain Symptoms.
    American family physician, 2015, Jul-01, Volume: 92, Issue:1

    Topics: Anticonvulsants; Diabetic Neuropathies; Humans; Levetiracetam; Neuralgia; Piracetam; Quality of Life

2015
[The effectiveness of levetiracetam in the treatment of neuropathic pain].
    Revista de neurologia, 2011, Jul-16, Volume: 53, Issue:2

    Topics: Anticonvulsants; Clinical Trials as Topic; Humans; Levetiracetam; Neuralgia; Piracetam; PubMed; Revi

2011