piracetam has been researched along with Muscle Spasticity in 7 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| " focuses on the current clinical development of the antiepileptic drug levetiracetam for amyotrophic lateral sclerosis." | 7.73 | Clinical development of levetiracetam for amyotrophic lateral sclerosis. ( Davies, SL; Moral, MA, 2006) |
| "Levetiracetam was well tolerated." | 6.74 | Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease. ( Bedlack, RS; Hawes, J; Heydt, D; Pastula, DM, 2009) |
| "Levetiracetam was effective for reducing phasic spasticity but not tonic spasticity in this 12-patient case series." | 5.32 | Levetiracetam for phasic spasticity in multiple sclerosis. ( Frohman, E; Hawker, K; Racke, M, 2003) |
| " focuses on the current clinical development of the antiepileptic drug levetiracetam for amyotrophic lateral sclerosis." | 3.73 | Clinical development of levetiracetam for amyotrophic lateral sclerosis. ( Davies, SL; Moral, MA, 2006) |
| "Levetiracetam was well tolerated." | 2.74 | Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease. ( Bedlack, RS; Hawes, J; Heydt, D; Pastula, DM, 2009) |
| "Levetiracetam was effective for reducing phasic spasticity but not tonic spasticity in this 12-patient case series." | 1.32 | Levetiracetam for phasic spasticity in multiple sclerosis. ( Frohman, E; Hawker, K; Racke, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bedlack, RS | 1 |
| Pastula, DM | 1 |
| Hawes, J | 1 |
| Heydt, D | 1 |
| Osman, NI | 1 |
| Lorincz, MT | 1 |
| Hulsing, KL | 1 |
| Gebarski, SS | 1 |
| Hawker, K | 1 |
| Frohman, E | 1 |
| Racke, M | 1 |
| Rüegg, SJ | 1 |
| Steck, AJ | 1 |
| Fuhr, P | 1 |
| Zafonte, R | 1 |
| Lombard, L | 1 |
| Elovic, E | 1 |
| Davies, SL | 1 |
| Moral, MA | 1 |
| Maritz, NG | 1 |
| Müller, FO | 1 |
| Pompe van Meerdervoort, HF | 1 |
1 review available for piracetam and Muscle Spasticity
| Article | Year |
|---|---|
Antispasticity medications: uses and limitations of enteral therapy.
Topics: 4-Aminopyridine; Acetates; Adrenergic alpha-Agonists; Amines; Baclofen; Benzodiazepines; Cyclohexane | 2004 |
2 trials available for piracetam and Muscle Spasticity
| Article | Year |
|---|---|
Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease.
Topics: Adult; Aged; Anticonvulsants; Disease Progression; Humans; Levetiracetam; Middle Aged; Motor Neuron | 2009 |
Piracetam in the management of spasticity in cerebral palsy.
Topics: Adolescent; Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Evaluation Studies as | 1978 |
4 other studies available for piracetam and Muscle Spasticity
| Article | Year |
|---|---|
Leukoencephalopathy, cerebral calcifications, and cysts: case report.
Topics: Adult; Anticonvulsants; Basal Ganglia Diseases; Brain; Calcinosis; Central Nervous System Cysts; Dys | 2012 |
Levetiracetam for phasic spasticity in multiple sclerosis.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Female; Humans; Levetiracetam; Male; Middl | 2003 |
Levetiracetam improves paroxysmal symptoms in a patient with stiff-person syndrome.
Topics: Female; GABA Agonists; Humans; Immunoglobulins, Intravenous; Levetiracetam; Middle Aged; Muscle Spas | 2004 |
Clinical development of levetiracetam for amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anticonvulsants; Clinical Trials as Topic; Humans; Levetirac | 2006 |