Page last updated: 2024-11-02

piracetam and Liver Diseases

piracetam has been researched along with Liver Diseases in 7 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the risk factors, clinical implications, and prognosis of new-onset seizures that occurred after pediatric liver transplantation, and to assess the efficacy of levetiracetam treatment."7.85Seizures in Pediatric Patients With Liver Transplant and Efficacy of Levetiracetam. ( Arslan, M; Güngör, S; Kılıç, B; Selimoğlu, MA; Yılmaz, S, 2017)
" In Phase II/III trials, the adverse effects occurring more commonly in the treatment groups versus the placebo group were; somnolence (14."6.42Levetiracetam safety profiles and tolerability in epilepsy patients. ( Briggs, DE; French, JA, 2004)
"The aim of this study was to evaluate the risk factors, clinical implications, and prognosis of new-onset seizures that occurred after pediatric liver transplantation, and to assess the efficacy of levetiracetam treatment."3.85Seizures in Pediatric Patients With Liver Transplant and Efficacy of Levetiracetam. ( Arslan, M; Güngör, S; Kılıç, B; Selimoğlu, MA; Yılmaz, S, 2017)
" Pharmacokinetic studies of levetiracetam have been conducted in healthy volunteers, in adults, children and elderly patients with epilepsy, and in patients with renal and hepatic impairment."2.42Clinical pharmacokinetics of levetiracetam. ( Patsalos, PN, 2004)
" In Phase II/III trials, the adverse effects occurring more commonly in the treatment groups versus the placebo group were; somnolence (14."2.42Levetiracetam safety profiles and tolerability in epilepsy patients. ( Briggs, DE; French, JA, 2004)
"Levetiracetam is a novel orally active antiepileptic drug with a unique preclinical profile."2.41Pharmacokinetic profile of levetiracetam: toward ideal characteristics. ( Patsalos, PN, 2000)
" The results of these studies indicate that higher doses need to be used for children (on a per-weight basis), and individuals with renal dysfunction require dosage modifications related to creatinine clearance."2.41Use of levetiracetam in special populations. ( French, J, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kılıç, B1
Güngör, S1
Arslan, M1
Selimoğlu, MA1
Yılmaz, S1
Ghosh, P1
Motamedi, G1
Osborne, B1
Mora, CA1
Patsalos, PN2
Briggs, DE1
French, JA1
French, J1
Sokolova, GB1
Nikolaev, VP1
Braude, VI1
Ziia, AV1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Study of Pharmacokinetics of Levetiracetam in Patients Undergoing Intermittent Hemodialysis[NCT04511676]12 participants (Actual)Observational2018-11-01Completed
Lamotrigine Versus Levetiracetam in the Initial Monotherapy of Epilepsy: An Open, Prospective, Multicenter, Randomized Phase III Study[NCT00242606]Phase 3409 participants (Actual)Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for piracetam and Liver Diseases

ArticleYear
Clinical pharmacokinetics of levetiracetam.
    Clinical pharmacokinetics, 2004, Volume: 43, Issue:11

    Topics: Adult; Aged; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Child; Drug Interactions; Dru

2004
Levetiracetam safety profiles and tolerability in epilepsy patients.
    Expert opinion on drug safety, 2004, Volume: 3, Issue:5

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Aged; Animals; Anticonvulsants; Astheni

2004
Pharmacokinetic profile of levetiracetam: toward ideal characteristics.
    Pharmacology & therapeutics, 2000, Volume: 85, Issue:2

    Topics: Absorption; Adolescent; Adult; Aged; Anticonvulsants; Child; Cytochrome P-450 Enzyme System; Drug In

2000
Pharmacokinetic profile of levetiracetam: toward ideal characteristics.
    Pharmacology & therapeutics, 2000, Volume: 85, Issue:2

    Topics: Absorption; Adolescent; Adult; Aged; Anticonvulsants; Child; Cytochrome P-450 Enzyme System; Drug In

2000
Pharmacokinetic profile of levetiracetam: toward ideal characteristics.
    Pharmacology & therapeutics, 2000, Volume: 85, Issue:2

    Topics: Absorption; Adolescent; Adult; Aged; Anticonvulsants; Child; Cytochrome P-450 Enzyme System; Drug In

2000
Pharmacokinetic profile of levetiracetam: toward ideal characteristics.
    Pharmacology & therapeutics, 2000, Volume: 85, Issue:2

    Topics: Absorption; Adolescent; Adult; Aged; Anticonvulsants; Child; Cytochrome P-450 Enzyme System; Drug In

2000
Use of levetiracetam in special populations.
    Epilepsia, 2001, Volume: 42 Suppl 4

    Topics: Adult; Age Factors; Aged; Anticonvulsants; Child; Comorbidity; Contraceptives, Oral; Drug Approval;

2001

Other Studies

3 other studies available for piracetam and Liver Diseases

ArticleYear
Seizures in Pediatric Patients With Liver Transplant and Efficacy of Levetiracetam.
    Journal of child neurology, 2017, Volume: 32, Issue:8

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Female; Humans; Infant

2017
Reversible blindness: simple partial seizures presenting as ictal and postictal hemianopsia.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2010, Volume: 30, Issue:3

    Topics: Adult; Anticonvulsants; Brain; Electroencephalography; Epilepsies, Partial; Female; Hemianopsia; Hum

2010
[Drug prophylaxis of liver lesions induced by isoniazid and its metabolites].
    Problemy tuberkuleza, 1989, Issue:5

    Topics: Animals; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Female; Inosine Diphospha

1989