Page last updated: 2024-11-02

piracetam and Kidney Failure

piracetam has been researched along with Kidney Failure in 6 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
"A 17-year-old girl who had started on levetiracetam because of new onset partial complex seizures developed acute renal failure and biopsy-confirmed interstitial nephritis 10 days after starting the drug."7.75Levetiracetam induced interstitial nephritis and renal failure. ( Hurwitz, KA; Ingulli, EG; Krous, HF, 2009)
"Levetiracetam was started with a good response."5.40Levetiracetam following liver and kidney failure in late-onset anticonvulsant hypersensitivity syndrome. ( López-González, FJ; Novoa, D; Pardo, J; Pintos, E; Rodríguez-Osorio, X, 2014)
" Levetiracetam is one of the new generation of AEDs licensed as an add-on therapy for the treatment of patients with partial-onset seizures."4.82Safety profile of levetiracetam. ( Arroyo, S; Crawford, P, 2003)
"A 17-year-old girl who had started on levetiracetam because of new onset partial complex seizures developed acute renal failure and biopsy-confirmed interstitial nephritis 10 days after starting the drug."3.75Levetiracetam induced interstitial nephritis and renal failure. ( Hurwitz, KA; Ingulli, EG; Krous, HF, 2009)
" Noncompartmental pharmacokinetic parameters were calculated and steady-state profiles were simulated using the superposition method."2.79Levetiracetam pharmacokinetics in Japanese subjects with renal impairment. ( Kumagai, Y; Stockis, A; Toublanc, N; Yamamoto, J, 2014)
" The peak concentration at steady state was 32."1.43Levetiracetam Pharmacokinetics During Continuous Venovenous Hemofiltration and Acute Liver Dysfunction. ( Frazee, EN; Kashani, KB; Nei, SD; New, AM; Rabinstein, AA, 2016)
"Levetiracetam was started with a good response."1.40Levetiracetam following liver and kidney failure in late-onset anticonvulsant hypersensitivity syndrome. ( López-González, FJ; Novoa, D; Pardo, J; Pintos, E; Rodríguez-Osorio, X, 2014)
"Levetiracetam is a broad spectrum anti-epileptic drug with renal elimination and no hepatic metabolism."1.35Levetiracetam accumulation in renal failure causing myoclonic encephalopathy with triphasic waves. ( Iwanowski, P; Jallon, P; Landis, T; Vulliemoz, S, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rodríguez-Osorio, X1
Pardo, J1
López-González, FJ1
Novoa, D1
Pintos, E1
Yamamoto, J1
Toublanc, N1
Kumagai, Y1
Stockis, A1
New, AM1
Nei, SD1
Kashani, KB1
Rabinstein, AA1
Frazee, EN1
Vulliemoz, S1
Iwanowski, P1
Landis, T1
Jallon, P1
Hurwitz, KA1
Ingulli, EG1
Krous, HF1
Arroyo, S1
Crawford, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Study of Pharmacokinetics of Levetiracetam in Patients Undergoing Intermittent Hemodialysis[NCT04511676]12 participants (Actual)Observational2018-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for piracetam and Kidney Failure

ArticleYear
Safety profile of levetiracetam.
    Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5 Suppl 1

    Topics: Age Factors; Anticonvulsants; Drug Interactions; Epilepsy; Humans; Levetiracetam; Persons with Menta

2003

Trials

1 trial available for piracetam and Kidney Failure

ArticleYear
Levetiracetam pharmacokinetics in Japanese subjects with renal impairment.
    Clinical drug investigation, 2014, Volume: 34, Issue:11

    Topics: Adult; Aged; Animals; Case-Control Studies; Dose-Response Relationship, Drug; Humans; Japan; Kidney

2014

Other Studies

4 other studies available for piracetam and Kidney Failure

ArticleYear
Levetiracetam following liver and kidney failure in late-onset anticonvulsant hypersensitivity syndrome.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:5

    Topics: Anticonvulsants; Drug Hypersensitivity Syndrome; Epilepsy; Humans; Levetiracetam; Liver Failure; Mal

2014
Levetiracetam Pharmacokinetics During Continuous Venovenous Hemofiltration and Acute Liver Dysfunction.
    Neurocritical care, 2016, Volume: 25, Issue:1

    Topics: Anticonvulsants; Hemofiltration; Humans; Levetiracetam; Liver Failure, Acute; Male; Middle Aged; Pir

2016
Levetiracetam accumulation in renal failure causing myoclonic encephalopathy with triphasic waves.
    Seizure, 2009, Volume: 18, Issue:5

    Topics: Aged, 80 and over; Anticonvulsants; Electroencephalography; Epilepsies, Myoclonic; Female; Humans; L

2009
Levetiracetam induced interstitial nephritis and renal failure.
    Pediatric neurology, 2009, Volume: 41, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Anticonvulsants; Contraindications; Female; Humans; Kidney; Lev

2009