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piracetam and Innate Inflammatory Response

piracetam has been researched along with Innate Inflammatory Response in 11 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Research Excerpts

ExcerptRelevanceReference
"The present study was performed to investigate the effect of piracetam on neuroinflammation induced by lipopolysaccharide (LPS) and resulting changes in cognitive behavior."7.85Piracetam Attenuates LPS-Induced Neuroinflammation and Cognitive Impairment in Rats. ( Krishnamurthy, S; Paliwal, P; Tripathi, A, 2017)
"Levetiracetam (200-1000 nmol/paw) produced a significant dose-dependent reduction of the paw inflammatory hyperalgesia and edema induced by carrageenan."7.78The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model. ( Micov, AM; Stepanović-Petrović, RM; Tomić, MA; Ugrešić, ND, 2012)
"The effect of piracetam has been studied in experimental models of the inflammatory process--the models of rat's paw oedema and intraperitoneal formalin ascites for the exudative phase and the cotton pellet model for the proliferative phase."7.67Effect of piracetam in models of experimental inflammation. ( Dushkova, R; Nikolova, M; Petrova, L, 1984)
" The pharmacokinetic profiles of R-PhP in mouse plasma and its bioavailability in brain tissue were assessed."5.56Neuroprotective and anti-inflammatory activity of DAT inhibitor R-phenylpiracetam in experimental models of inflammation in male mice. ( Dambrova, M; Grinberga, S; Stelfa, G; Svalbe, B; Vavers, E; Videja, M; Zvejniece, B; Zvejniece, L, 2020)
"Levetiracetam (LEV) suppresses the upregulation of proinflammatory molecules that occurs during epileptogenesis after status epilepticus (SE)."4.12Regulation of Inflammation-Related Genes through ( Hashimoto, R; Ishihara, Y; Itoh, K; Komori, R; Kono, T; Kozawa, C; Kubo, S; Matsuo, T; Yokota-Nakatsuma, A, 2022)
"The present study was performed to investigate the effect of piracetam on neuroinflammation induced by lipopolysaccharide (LPS) and resulting changes in cognitive behavior."3.85Piracetam Attenuates LPS-Induced Neuroinflammation and Cognitive Impairment in Rats. ( Krishnamurthy, S; Paliwal, P; Tripathi, A, 2017)
" These results suggest that ceftriaxone, particularly in combinations with ibuprofen, celecoxib, paracetamol, or levetiracetam, may provide useful approach to the clinical treatment of inflammation-related pain."3.80Antihyperalgesic/antinociceptive effects of ceftriaxone and its synergistic interactions with different analgesics in inflammatory pain in rodents. ( Boškovic, BD; Kovacevic, JM; Micov, AM; Stepanovic-Petrovic, RM; Tomic, MA, 2014)
" This study characterized the manner in which levetiracetam interacts with analgesics (ibuprofen, celecoxib, and paracetamol) and caffeine to suppress hyperalgesia in a model of localized inflammation."3.79Levetiracetam interacts synergistically with nonsteroidal analgesics and caffeine to produce antihyperalgesia in rats. ( Micov, AM; Stepanović-Petrović, RM; Tomić, MA, 2013)
"Levetiracetam (200-1000 nmol/paw) produced a significant dose-dependent reduction of the paw inflammatory hyperalgesia and edema induced by carrageenan."3.78The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model. ( Micov, AM; Stepanović-Petrović, RM; Tomić, MA; Ugrešić, ND, 2012)
"The effect of piracetam has been studied in experimental models of the inflammatory process--the models of rat's paw oedema and intraperitoneal formalin ascites for the exudative phase and the cotton pellet model for the proliferative phase."3.67Effect of piracetam in models of experimental inflammation. ( Dushkova, R; Nikolova, M; Petrova, L, 1984)
" The pharmacokinetic profiles of R-PhP in mouse plasma and its bioavailability in brain tissue were assessed."1.56Neuroprotective and anti-inflammatory activity of DAT inhibitor R-phenylpiracetam in experimental models of inflammation in male mice. ( Dambrova, M; Grinberga, S; Stelfa, G; Svalbe, B; Vavers, E; Videja, M; Zvejniece, B; Zvejniece, L, 2020)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Komori, R1
Matsuo, T1
Yokota-Nakatsuma, A1
Hashimoto, R1
Kubo, S1
Kozawa, C1
Kono, T1
Ishihara, Y1
Itoh, K1
Zvejniece, L1
Zvejniece, B1
Videja, M1
Stelfa, G1
Vavers, E1
Grinberga, S1
Svalbe, B1
Dambrova, M1
Block, L1
Björklund, U1
Westerlund, A1
Jörneberg, P1
Biber, B1
Hansson, E1
Tomić, MA3
Micov, AM3
Stepanović-Petrović, RM3
Kovacevic, JM1
Boškovic, BD1
Tyurenkov, IN1
Samotrueva, MA1
Tsibizova, AA1
Yasenyavskaya, AL1
Tripathi, A1
Paliwal, P1
Krishnamurthy, S1
Ugrešić, ND1
Marini, H1
Costa, C1
Passaniti, M1
Esposito, M1
Campo, GM1
Ientile, R1
Adamo, EB1
Marini, R1
Calabresi, P1
Altavilla, D1
Minutoli, L1
Pisani, F1
Squadrito, F1
Nikolova, M1
Petrova, L1
Dushkova, R1

Other Studies

11 other studies available for piracetam and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Regulation of Inflammation-Related Genes through
    International journal of molecular sciences, 2022, Jul-09, Volume: 23, Issue:14

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Inflammation; Levetiracetam; Mice; Piloc

2022
Neuroprotective and anti-inflammatory activity of DAT inhibitor R-phenylpiracetam in experimental models of inflammation in male mice.
    Inflammopharmacology, 2020, Volume: 28, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Brain; Disease Models, Animal; Dopamine

2020
A new concept affecting restoration of inflammation-reactive astrocytes.
    Neuroscience, 2013, Oct-10, Volume: 250

    Topics: Actins; Analgesics, Opioid; Animals; Astrocytes; Calcium Signaling; Capillaries; Coculture Technique

2013
Levetiracetam interacts synergistically with nonsteroidal analgesics and caffeine to produce antihyperalgesia in rats.
    The journal of pain, 2013, Volume: 14, Issue:11

    Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Celecoxib; Dr

2013
Antihyperalgesic/antinociceptive effects of ceftriaxone and its synergistic interactions with different analgesics in inflammatory pain in rodents.
    Anesthesiology, 2014, Volume: 120, Issue:3

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Ceftriaxone; Ce

2014
[PHENOTROPIL AS MODULATOR OF CYTOKINE LEVEL UNDER CONDITIONS OF EXPERIMENTAL IMMUNOPATHOLOGY].
    Eksperimental'naia i klinicheskaia farmakologiia, 2015, Volume: 78, Issue:12

    Topics: Animals; Cyclophosphamide; Drug Administration Schedule; Immunity, Innate; Immunologic Factors; Immu

2015
Piracetam Attenuates LPS-Induced Neuroinflammation and Cognitive Impairment in Rats.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:8

    Topics: Animals; Cognitive Dysfunction; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediato

2017
The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:6

    Topics: Adenosine A1 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Carrag

2012
Levetiracetam protects against kainic acid-induced toxicity.
    Life sciences, 2004, Jan-23, Volume: 74, Issue:10

    Topics: Animals; Behavior, Animal; Brain; Cells, Cultured; Cerebral Cortex; Diencephalon; DNA Primers; Excit

2004
Effect of piracetam in models of experimental inflammation.
    International journal of tissue reactions, 1984, Volume: 6, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Ascites; Cell Membrane Permeability; Dose-Response Relationship,

1984