piracetam has been researched along with Huntington Disease in 3 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Piracetam has been described to improve neuroleptic-induced acute extrapyramidal syndrome where a central dopaminergic hyperactivity is implicated." | 2.65 | Effect of piracetam in Huntington's chorea. ( Destée, A; Petit, H; Warot, P, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zesiewicz, TA | 1 |
| Sullivan, KL | 1 |
| Hauser, RA | 1 |
| Sanchez-Ramos, J | 1 |
| Destée, A | 1 |
| Petit, H | 1 |
| Warot, P | 1 |
| Mateo, D | 1 |
| Giménez-Roldán, S | 1 |
2 trials available for piracetam and Huntington Disease
| Article | Year |
|---|---|
Effect of piracetam in Huntington's chorea.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Huntington Disease; Injections, Intravenous; | 1984 |
[The effect of piracetam on involuntary movements in Huntington's disease. A double-blind, placebo-controlled study].
Topics: Adult; Double-Blind Method; Female; Humans; Huntington Disease; Injections, Intravenous; Male; Middl | 1996 |
1 other study available for piracetam and Huntington Disease
| Article | Year |
|---|---|
Open-label pilot study of levetiracetam (Keppra) for the treatment of chorea in Huntington's disease.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hun | 2006 |