piracetam has been researched along with Headache in 21 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To prospectively assess the safety and efficacy of levetiracetam in patients with uncontrolled focal epilepsy, in a common practice-based setting." | 9.12 | Levetiracetam in a broad population of patients with refractory epilepsy: interim results of the international SKATE trial. ( Despland, PA; Fejerman, N; Genton, P; Maubrey, MC; Peltola, J; Rektor, I; Sadzot, B; Schlit, AF; Steinhoff, B; van Hammée, G; van Paesschen, W; Vandervelden, C; Wroe, S, 2006) |
| "The effect of piracetam, a cyclical derivative of GABA, was compared with that of a placebo in a double-blind study of 60 patients with post-concussional syndrome of 2-12 months' duration." | 9.04 | Piracetam in the treatment of post-concussional syndrome. A double-blind study. ( Hakamies, L; Hakkarainen, H, 1978) |
| " In Phase II/III trials, the adverse effects occurring more commonly in the treatment groups versus the placebo group were; somnolence (14." | 6.42 | Levetiracetam safety profiles and tolerability in epilepsy patients. ( Briggs, DE; French, JA, 2004) |
| "To prospectively assess the safety and efficacy of levetiracetam in patients with uncontrolled focal epilepsy, in a common practice-based setting." | 5.12 | Levetiracetam in a broad population of patients with refractory epilepsy: interim results of the international SKATE trial. ( Despland, PA; Fejerman, N; Genton, P; Maubrey, MC; Peltola, J; Rektor, I; Sadzot, B; Schlit, AF; Steinhoff, B; van Hammée, G; van Paesschen, W; Vandervelden, C; Wroe, S, 2006) |
| "The effect of piracetam, a cyclical derivative of GABA, was compared with that of a placebo in a double-blind study of 60 patients with post-concussional syndrome of 2-12 months' duration." | 5.04 | Piracetam in the treatment of post-concussional syndrome. A double-blind study. ( Hakamies, L; Hakkarainen, H, 1978) |
| "Levetiracetam is a novel antiepileptic drug which has shown strong anti-kindling activity in animal models of epilepsy." | 2.73 | Levetiracetam for treatment of premenstrual dysphoric disorder: a pilot, open-label study. ( Halbreich, U; Kayatekin, ZE; Sabo, AN, 2008) |
| " Adverse events were reported in 34 (72." | 2.72 | Efficacy and safety of levetiracetam (up to 2000 mg/day) in Taiwanese patients with refractory partial seizures: a multicenter, randomized, double-blind, placebo-controlled study. ( Chen, SS; Edrich, P; Hiersemenzel, R; Hsih, MS; Lai, CW; Tsai, JJ; Yen, DJ, 2006) |
" Adverse events reported after IV administration of LEV (| 2.72 | Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study. ( Daoust, A; Lu, ZS; Otoul, C; Ramael, S; Stockis, A; Toublanc, N; Troenaru, M, 2006) | |
| " Further work should be carried out with larger sample sizes and optimal dosing strategies of the drug." | 2.71 | Levetiracetam in social phobia: a placebo controlled pilot study. ( Connor, KM; Davidson, JR; Zhang, W, 2005) |
| " The most commonly reported adverse events were headache, infection, anorexia, and somnolence." | 2.70 | Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial. ( Bebin, EM; Fountain, NB; Glauser, TA; Jensen, CM; Pellock, JM; Ritter, FJ; Shields, WD, 2002) |
| "Pediatric migraine can cause a significant impact on quality of life." | 2.45 | [Antiepileptic drugs for the prevention of pediatric migraine]. ( Cuvellier, JC, 2009) |
| " In Phase II/III trials, the adverse effects occurring more commonly in the treatment groups versus the placebo group were; somnolence (14." | 2.42 | Levetiracetam safety profiles and tolerability in epilepsy patients. ( Briggs, DE; French, JA, 2004) |
| "When lamotrigine was restarted 2 weeks later she developed similar but more severe symptoms which resolved on stopping lamotrigine." | 1.35 | Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis. ( Bazaz, R; Lily, O; Maniyar, F; Rooney, C, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McNally, MA | 1 |
| Kossoff, EH | 1 |
| McKee, KE | 1 |
| Etherton, MR | 1 |
| Lovitch, SB | 1 |
| Gupta, AS | 1 |
| Micalizzi, DS | 1 |
| Tierney, T | 1 |
| Wadleigh, M | 1 |
| Vaitkevicus, H | 1 |
| Halbert, RK | 1 |
| Maniyar, F | 1 |
| Rooney, C | 1 |
| Lily, O | 1 |
| Bazaz, R | 1 |
| Cuvellier, JC | 1 |
| Zakharov, VV | 1 |
| Kang, SY | 1 |
| Han, YM | 1 |
| Choi, K | 1 |
| Hwang, SH | 1 |
| Bhandari, HS | 1 |
| Briggs, DE | 1 |
| French, JA | 1 |
| Frediani, F | 1 |
| Zhang, W | 1 |
| Connor, KM | 1 |
| Davidson, JR | 1 |
| Tsai, JJ | 1 |
| Yen, DJ | 1 |
| Hsih, MS | 1 |
| Chen, SS | 1 |
| Hiersemenzel, R | 1 |
| Edrich, P | 1 |
| Lai, CW | 1 |
| Genton, P | 1 |
| Sadzot, B | 1 |
| Fejerman, N | 1 |
| Peltola, J | 1 |
| Despland, PA | 1 |
| Steinhoff, B | 1 |
| Rektor, I | 1 |
| Wroe, S | 1 |
| Maubrey, MC | 1 |
| Vandervelden, C | 1 |
| van Hammée, G | 1 |
| Schlit, AF | 1 |
| van Paesschen, W | 1 |
| Ramael, S | 1 |
| Daoust, A | 1 |
| Otoul, C | 1 |
| Toublanc, N | 1 |
| Troenaru, M | 1 |
| Lu, ZS | 1 |
| Stockis, A | 2 |
| Baulac, M | 1 |
| Brodie, MJ | 1 |
| Elger, CE | 1 |
| Krakow, K | 1 |
| Meyvisch, P | 1 |
| Falter, U | 1 |
| Kayatekin, ZE | 1 |
| Sabo, AN | 1 |
| Halbreich, U | 1 |
| Garaizar, C | 1 |
| Prats, JM | 1 |
| Zuazo, E | 1 |
| Zed, PJ | 1 |
| Loewen, PS | 1 |
| Robinson, G | 1 |
| Glauser, TA | 1 |
| Pellock, JM | 1 |
| Bebin, EM | 1 |
| Fountain, NB | 1 |
| Ritter, FJ | 1 |
| Jensen, CM | 1 |
| Shields, WD | 1 |
| Hakkarainen, H | 1 |
| Hakamies, L | 1 |
| Bäker, BA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trial Studying the Safety and Efficacy of Keppra® as Adjunctive Therapy in Adult Patients With Uncontrolled Partial Epilepsy[NCT00630968] | Phase 4 | 1,541 participants (Actual) | Interventional | 2000-08-31 | Completed | ||
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| Intravenous Levetiracetam as First-line Anticonvulsive Treatment in Patients With Non-convulsive Status Epilepticus[NCT00603135] | Phase 2 | 0 participants (Actual) | Interventional | 2008-01-31 | Withdrawn | ||
| A Pharmacokinetic Analysis of Levetiracetam Prophylaxis in Critically Ill Patients With Severe Traumatic Brain Injury[NCT04836481] | 20 participants (Anticipated) | Observational | 2021-01-01 | Recruiting | |||
| Trial Evaluating the Safety and Tolerability of Levetiracetam Intravenous 15-minute Infusion, Administered in b.i.d. Regimen as an Adjunctive Antiepileptic Treatment in Subjects From 16 to 65 Years Suffering From Partial Onset Seizures[NCT00610454] | Phase 2 | 25 participants (Actual) | Interventional | 2004-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for piracetam and Headache
| Article | Year |
|---|---|
[Antiepileptic drugs for the prevention of pediatric migraine].
Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Tolerance; Fructose; G | 2009 |
Presentation of opsoclonus myoclonus ataxia syndrome with glutamic acid decarboxylase antibodies.
Topics: Adult; Anticonvulsants; Anxiety; Ataxia; Autoantibodies; Diagnosis, Differential; Earache; Female; F | 2012 |
Levetiracetam safety profiles and tolerability in epilepsy patients.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Aged; Animals; Anticonvulsants; Astheni | 2004 |
Anticonvulsant drugs in primary headaches prophylaxis.
Topics: Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fruct | 2004 |
Medication-induced headache: overview and systematic review of therapeutic approaches.
Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Chronic Disease; Ergolines; Headache; Humans; M | 1999 |
9 trials available for piracetam and Headache
| Article | Year |
|---|---|
Levetiracetam in social phobia: a placebo controlled pilot study.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blind Method; Female; Headache; Hum | 2005 |
Efficacy and safety of levetiracetam (up to 2000 mg/day) in Taiwanese patients with refractory partial seizures: a multicenter, randomized, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Cross-Over Studies; Dizziness; Double-Blind Method | 2006 |
Levetiracetam in a broad population of patients with refractory epilepsy: interim results of the international SKATE trial.
Topics: Adult; Anticonvulsants; Disorders of Excessive Somnolence; Dizziness; Dose-Response Relationship, Dr | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.
Topics: Administration, Oral; Adult; Anticonvulsants; Area Under Curve; Blood Pressure; Disorders of Excessi | 2006 |
Levetiracetam intravenous infusion as an alternative to oral dosing in patients with partial-onset seizures.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Drug Administration Schedule; Drug T | 2007 |
Levetiracetam for treatment of premenstrual dysphoric disorder: a pilot, open-label study.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Foll | 2008 |
[Response to prophylactic treatment of benign headache in children].
Topics: Calcium Channel Blockers; Child; Female; Flunarizine; Headache; Humans; Male; Nootropic Agents; Pira | 1998 |
Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial.
Topics: Age Factors; Age of Onset; Anorexia; Anticonvulsants; Child; Drug Administration Schedule; Drug Ther | 2002 |
Piracetam in the treatment of post-concussional syndrome. A double-blind study.
Topics: Brain Concussion; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Fatigue; Headache; | 1978 |
7 other studies available for piracetam and Headache
| Article | Year |
|---|---|
Incidental rolandic spikes: long-term outcomes and impact of treatment.
Topics: Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Rolandic; Female; Follow | 2015 |
A Man in His 40s With Headache, Lethargy, and Altered Mental Status.
Topics: Adult; Antineoplastic Agents, Hormonal; Craniotomy; Dexamethasone; DNA Nucleotidylexotransferase; He | 2015 |
Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Study.
Topics: Adult; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Anticonvulsants; Cyclophosphamide; Fatal Out | 2016 |
Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis.
Topics: Anti-Bacterial Agents; Anticonvulsants; Drug Administration Schedule; Drug-Related Side Effects and | 2009 |
[Vinpotropil in the treatment of dyscirculatory encephalopathy with cognitive impairment without dementia].
Topics: Adult; Aged; Cognition Disorders; Dementia, Vascular; Dizziness; Drug Administration Schedule; Drug | 2010 |
Neurological picture. Transient high-intensity signal of heterotopia on DWI in an epilepsy patient.
Topics: Anticonvulsants; Brain; Carbamazepine; Choristoma; Consciousness Disorders; Diagnosis, Differential; | 2012 |
[Migraine and headache in children].
Topics: Child; Headache; Humans; Male; Manipulation, Orthopedic; Migraine Disorders; Piracetam | 1977 |