piracetam has been researched along with Glial Cell Tumors in 19 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures." | 9.14 | Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study. ( Barbaro, N; Burt, M; Chakalian, L; Chang, E; Chang, S; Lamborn, KR; Lim, DA; McDermott, MW; Tarapore, P, 2009) |
| "To determine the safety and tolerability of IV and oral levetiracetam monotherapy for seizures in brain tumor patients following resection." | 8.86 | A prospective evaluation and literature review of levetiracetam use in patients with brain tumors and seizures. ( Finch, CK; Michael, LM; Sills, AK; Usery, JB, 2010) |
| "To correlate SV2A expression in surgically removed tumor and peritumoral tissue of glioma patients with epilepsy with the clinical response to levetiracetam in a prospective cohort." | 7.77 | Synaptic vesicle protein 2A predicts response to levetiracetam in patients with glioma. ( Aronica, E; de Groot, M; Heimans, JJ; Reijneveld, JC, 2011) |
| "To evaluate the efficacy and safety of levetiracetam in the management of epilepsy in patients with glioma." | 7.76 | Efficacy and safety of levetiracetam in patients with glioma: a clinical prospective study. ( Buttolo, L; Cenzato, M; Padovani, A; Rosati, A; Stefini, R; Todeschini, A, 2010) |
| "In this study, patients with glioma treated with levetiracetam and phenytoin had similar seizure control." | 7.76 | Seizures in patients with glioma treated with phenytoin and levetiracetam. ( Anderson, SK; Lachance, DH; Merrell, RT; Meyer, FB, 2010) |
| "Levetiracetam (LEV) is a newer anticonvulsant with a favorable safety profile." | 6.77 | Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery: the HELLO trial. ( Bähr, O; Franz, K; Hermisson, M; Körtvelyessy, P; Nussbaum, S; Rieger, J; Rona, S; Seifert, V; Steinbach, JP; Tatagiba, M; Weller, M, 2012) |
| "Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures." | 5.14 | Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study. ( Barbaro, N; Burt, M; Chakalian, L; Chang, E; Chang, S; Lamborn, KR; Lim, DA; McDermott, MW; Tarapore, P, 2009) |
| "To determine the safety and tolerability of IV and oral levetiracetam monotherapy for seizures in brain tumor patients following resection." | 4.86 | A prospective evaluation and literature review of levetiracetam use in patients with brain tumors and seizures. ( Finch, CK; Michael, LM; Sills, AK; Usery, JB, 2010) |
| "We report the case of an aborted awake craniotomy for a left frontotemporoinsular glioma due to ammonia encephalopathy on a patient taking Levetiracetam, valproic acid and clobazam." | 3.81 | Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy. ( Arroyo Pérez, R; Fernández-Candil, JL; León Jorba, A; Pacreu Terradas, S; Villalba Martínez, G; Vivanco-Hidalgo, RM, 2015) |
| "To correlate SV2A expression in surgically removed tumor and peritumoral tissue of glioma patients with epilepsy with the clinical response to levetiracetam in a prospective cohort." | 3.77 | Synaptic vesicle protein 2A predicts response to levetiracetam in patients with glioma. ( Aronica, E; de Groot, M; Heimans, JJ; Reijneveld, JC, 2011) |
| "To evaluate the efficacy and safety of levetiracetam in the management of epilepsy in patients with glioma." | 3.76 | Efficacy and safety of levetiracetam in patients with glioma: a clinical prospective study. ( Buttolo, L; Cenzato, M; Padovani, A; Rosati, A; Stefini, R; Todeschini, A, 2010) |
| "In this study, patients with glioma treated with levetiracetam and phenytoin had similar seizure control." | 3.76 | Seizures in patients with glioma treated with phenytoin and levetiracetam. ( Anderson, SK; Lachance, DH; Merrell, RT; Meyer, FB, 2010) |
| "Levetiracetam (LEV) is a newer anticonvulsant with a favorable safety profile." | 2.77 | Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery: the HELLO trial. ( Bähr, O; Franz, K; Hermisson, M; Körtvelyessy, P; Nussbaum, S; Rieger, J; Rona, S; Seifert, V; Steinbach, JP; Tatagiba, M; Weller, M, 2012) |
| "In most cases, either the seizure or the medications used to treat the seizure may contribute to cognitive and psychosocial difficulties of various degrees of severity." | 2.52 | Clinical Management of Seizures in Patients With Low-Grade Glioma. ( Blakeley, J; Piotrowski, AF, 2015) |
| "Levetiracetam was very well tolerated." | 1.42 | Epilepsy in patients with gliomas: incidence and control of seizures. ( Hasegawa, Y; Iuchi, T; Kawasaki, K; Sakaida, T, 2015) |
| "Although seizures in brain tumor patients are common, the knowledge on optimal anti-seizure therapy in this patient group is limited." | 1.35 | Efficacy of anti-epileptic drugs in patients with gliomas and seizures. ( Rijsman, RM; Taphoorn, MJ; van Breemen, MS; Vecht, CJ; Walchenbach, R; Zwinkels, H, 2009) |
| "Levetiracetam was more likely to be used in children who received chemotherapy or radiation therapy (8/14, or 57%) than in those who did not receive adjuvant therapies (3/18, or 17%) (P = 0." | 1.35 | The use of antiepileptic drugs in pediatric brain tumor patients. ( Kan, L; Levy, AS; Maytal, J; Shinnar, S; Sogawa, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 12 (63.16) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Ju, IG | 1 |
| Hong, SM | 1 |
| Yun, SW | 1 |
| Huh, E | 1 |
| Kim, DH | 1 |
| Kim, SY | 1 |
| Oh, MS | 1 |
| van der Meer, PB | 1 |
| Dirven, L | 1 |
| Fiocco, M | 1 |
| Vos, MJ | 1 |
| Kouwenhoven, MCM | 1 |
| van den Bent, MJ | 1 |
| Taphoorn, MJB | 1 |
| Koekkoek, JAF | 1 |
| Iuchi, T | 1 |
| Hasegawa, Y | 1 |
| Kawasaki, K | 1 |
| Sakaida, T | 1 |
| Villalba Martínez, G | 1 |
| Fernández-Candil, JL | 1 |
| Vivanco-Hidalgo, RM | 1 |
| Pacreu Terradas, S | 1 |
| León Jorba, A | 1 |
| Arroyo Pérez, R | 1 |
| Piotrowski, AF | 1 |
| Blakeley, J | 1 |
| Ismail, FS | 1 |
| Moinfar, Z | 1 |
| Prochnow, N | 1 |
| Dambach, H | 1 |
| Hinkerohe, D | 1 |
| Haase, CG | 1 |
| Förster, E | 1 |
| Faustmann, PM | 1 |
| Shershever, AS | 1 |
| Bentsion, DL | 1 |
| Lavrova, SA | 1 |
| Sorokova, EV | 1 |
| Lim, DA | 1 |
| Tarapore, P | 1 |
| Chang, E | 1 |
| Burt, M | 1 |
| Chakalian, L | 1 |
| Barbaro, N | 1 |
| Chang, S | 1 |
| Lamborn, KR | 1 |
| McDermott, MW | 1 |
| van Breemen, MS | 1 |
| Rijsman, RM | 1 |
| Taphoorn, MJ | 1 |
| Walchenbach, R | 1 |
| Zwinkels, H | 1 |
| Vecht, CJ | 1 |
| Sogawa, Y | 1 |
| Kan, L | 1 |
| Levy, AS | 1 |
| Maytal, J | 1 |
| Shinnar, S | 1 |
| Usery, JB | 1 |
| Michael, LM | 1 |
| Sills, AK | 1 |
| Finch, CK | 1 |
| Rosati, A | 1 |
| Buttolo, L | 1 |
| Stefini, R | 1 |
| Todeschini, A | 1 |
| Cenzato, M | 1 |
| Padovani, A | 1 |
| Merrell, RT | 1 |
| Anderson, SK | 1 |
| Meyer, FB | 1 |
| Lachance, DH | 1 |
| Engh, JA | 1 |
| de Groot, M | 2 |
| Aronica, E | 1 |
| Heimans, JJ | 2 |
| Reijneveld, JC | 2 |
| Bähr, O | 1 |
| Hermisson, M | 1 |
| Rona, S | 1 |
| Rieger, J | 1 |
| Nussbaum, S | 1 |
| Körtvelyessy, P | 1 |
| Franz, K | 1 |
| Tatagiba, M | 1 |
| Seifert, V | 1 |
| Weller, M | 1 |
| Steinbach, JP | 1 |
| Hefti, M | 1 |
| Albert, I | 1 |
| Luginbuehl, V | 1 |
| Douw, L | 1 |
| Sizoo, EM | 1 |
| Bosma, I | 1 |
| Froklage, FE | 1 |
| Postma, TJ | 1 |
| Klein, M | 1 |
| Wagner, GL | 1 |
| Wilms, EB | 1 |
| Van Donselaar, CA | 1 |
| Vecht, ChJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study on Glioma Patients: Understanding Their Glioma Clinical Trial Experiences[NCT05958472] | 500 participants (Anticipated) | Observational | 2024-08-31 | Not yet recruiting | |||
| Prospective Trial of Intravenous Levetiracetam in Patients With Primary Brain Tumors and at Least One Symptomatic Seizure Who Undergo Biopsy or Cytoreductive Surgery (HELLO-study)[NCT00571155] | Phase 4 | 30 participants (Anticipated) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for piracetam and Glial Cell Tumors
| Article | Year |
|---|---|
Clinical Management of Seizures in Patients With Low-Grade Glioma.
Topics: Anticonvulsants; Brain Neoplasms; Glioma; Humans; Lamotrigine; Levetiracetam; Piracetam; Seizures; T | 2015 |
A prospective evaluation and literature review of levetiracetam use in patients with brain tumors and seizures.
Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Brain Neoplasms; Dose-Response Relationship, Dru | 2010 |
2 trials available for piracetam and Glial Cell Tumors
| Article | Year |
|---|---|
Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Neoplasms; Craniotomy; Female; Glioma; Humans | 2009 |
Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery: the HELLO trial.
Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Brain Neoplasms; Chemotherapy, Adjuvant; Electro | 2012 |
15 other studies available for piracetam and Glial Cell Tumors
| Article | Year |
|---|---|
CCL01, a novel formulation composed of
Topics: Animals; Cell Line, Tumor; Cuscuta; Cyclic AMP Response Element-Binding Protein; Extracellular Signa | 2021 |
Effectiveness of Antiseizure Medication Duotherapies in Patients With Glioma: A Multicenter Observational Cohort Study.
Topics: Anticonvulsants; Cohort Studies; Glioma; Humans; Levetiracetam; Piracetam; Retrospective Studies; Se | 2022 |
Epilepsy in patients with gliomas: incidence and control of seizures.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Female; Glioma; Humans; Inci | 2015 |
Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy.
Topics: Anesthesia, General; Anesthesia, Local; Anticonvulsants; Aphasia; Benzodiazepines; Brain Diseases; B | 2015 |
Dexamethasone and levetiracetam reduce hetero-cellular gap-junctional coupling between F98 glioma cells and glial cells in vitro.
Topics: Animals; Antineoplastic Agents; Astrocytes; Cell Communication; Cell Line, Tumor; Connexin 43; Conne | 2017 |
[Use of keppra during the radiotherapy in patients with brain tumors and epileptic seizures after surgical treatment].
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Brain Neoplasms; Child; Dose-Response Rela | 2008 |
Efficacy of anti-epileptic drugs in patients with gliomas and seizures.
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Drug Therapy, Combination; Female; Follow-Up | 2009 |
The use of antiepileptic drugs in pediatric brain tumor patients.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Child; Drug Interactions; Fo | 2009 |
Efficacy and safety of levetiracetam in patients with glioma: a clinical prospective study.
Topics: Adult; Aged; Anticonvulsants; Brain Neoplasms; Dose-Response Relationship, Drug; Epilepsy; Female; G | 2010 |
Seizures in patients with glioma treated with phenytoin and levetiracetam.
Topics: Adult; Aged; Anticonvulsants; Female; Glioma; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; P | 2010 |
Anti-convulsants and gene expression in malignant gliomas.
Topics: Brain Neoplasms; Convulsants; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplast | 2010 |
Synaptic vesicle protein 2A predicts response to levetiracetam in patients with glioma.
Topics: Adult; Aged; Blotting, Western; Brain Neoplasms; Cohort Studies; Epilepsy; False Positive Reactions; | 2011 |
Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells.
Topics: Aminolevulinic Acid; Anticonvulsants; Fluorescence; Glioma; Glutathione; Humans; Levetiracetam; Memb | 2012 |
Levetiracetam improves verbal memory in high-grade glioma patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Neoplasms; Cognition Disorders; Female; Glioma; Huma | 2013 |
Levetiracetam: preliminary experience in patients with primary brain tumours.
Topics: Brain Neoplasms; Follow-Up Studies; Glioma; Humans; Levetiracetam; Piracetam; Prospective Studies; S | 2003 |