piracetam has been researched along with Epilepsy, Tonic-Clonic in 22 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study, in a meaningful number of exposed pregnancies, confirms a low risk for MCM with levetiracetam monotherapy use in pregnancy." | 7.79 | Levetiracetam in pregnancy: results from the UK and Ireland epilepsy and pregnancy registers. ( Craig, J; Delanty, N; Hunt, SJ; Irwin, B; Liggan, B; Mawhinney, E; Morrison, PJ; Morrow, J; Parsons, L; Russell, A; Smithson, WH, 2013) |
| " MET test (PTZ at the dose of 70 mg/kg) acute seizures in Wistar rats, in comparison to valproic acid (VPA)." | 7.76 | Levetiracetam in submaximal subcutaneous pentylentetrazol-induced seizures in rats. ( Arcieri, S; Coppola, G; D'Aniello, A; Messana, T; Pascotto, A; Signoriello, G; Verrotti, A, 2010) |
| "Lennox-Gastaut syndrome is an epileptic encephalopathy characterized by multiple seizure types, mental retardation, and a slow spike-and-wave pattern on electroencephalography." | 5.32 | Levetiracetam in the treatment of Lennox-Gastaut syndrome. ( De Los Reyes, EC; Hale, SE; Sharp, GB; Williams, JP, 2004) |
| "In the GAERS model of petit mal epilepsy, levetiracetam markedly suppressed spontaneous spike-and-wave discharge (SWD) but left the underlying EEG trace normal." | 5.29 | Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy. ( Boehrer, A; Gower, AJ; Hirsch, E; Marescaux, C; Noyer, M, 1995) |
| "This study, in a meaningful number of exposed pregnancies, confirms a low risk for MCM with levetiracetam monotherapy use in pregnancy." | 3.79 | Levetiracetam in pregnancy: results from the UK and Ireland epilepsy and pregnancy registers. ( Craig, J; Delanty, N; Hunt, SJ; Irwin, B; Liggan, B; Mawhinney, E; Morrison, PJ; Morrow, J; Parsons, L; Russell, A; Smithson, WH, 2013) |
| " MET test (PTZ at the dose of 70 mg/kg) acute seizures in Wistar rats, in comparison to valproic acid (VPA)." | 3.76 | Levetiracetam in submaximal subcutaneous pentylentetrazol-induced seizures in rats. ( Arcieri, S; Coppola, G; D'Aniello, A; Messana, T; Pascotto, A; Signoriello, G; Verrotti, A, 2010) |
| "We present a patient with cryptogenic focal epilepsy and another with Dravet syndrome, who experienced seizure aggravation and negative myoclonus, associated with continuous spikes and waves during slow sleep, induced by levetiracetam." | 3.76 | Levetiracetam-induced seizure aggravation associated with continuous spikes and waves during slow sleep in children with refractory epilepsies. ( Caraballo, RH; Cersósimo, R; De los Santos, C, 2010) |
| "Occurrence of generalized tonic-clonic seizures (GTCS) is one of the most important risk factors of seizure-related complications and comorbidities in patients with epilepsy." | 2.50 | Pharmacotherapy for tonic-clonic seizures. ( Rheims, S; Ryvlin, P, 2014) |
| "The incidence of seizures is generally accepted to be greater in patients with multiple sclerosis (MS) than in the general population, and rarely, MS can initially present as seizure." | 1.37 | Seizures as a manifestation of multiple sclerosis. ( Kendrick-Adey, AC; Sponsler, JL, 2011) |
| "Lennox-Gastaut syndrome is an epileptic encephalopathy characterized by multiple seizure types, mental retardation, and a slow spike-and-wave pattern on electroencephalography." | 1.32 | Levetiracetam in the treatment of Lennox-Gastaut syndrome. ( De Los Reyes, EC; Hale, SE; Sharp, GB; Williams, JP, 2004) |
| "In the GAERS model of petit mal epilepsy, levetiracetam markedly suppressed spontaneous spike-and-wave discharge (SWD) but left the underlying EEG trace normal." | 1.29 | Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy. ( Boehrer, A; Gower, AJ; Hirsch, E; Marescaux, C; Noyer, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coppola, G | 2 |
| Piccorossi, A | 1 |
| Operto, FF | 1 |
| Verrotti, A | 2 |
| Calabrò, RS | 1 |
| Bramanti, P | 1 |
| Spina, E | 1 |
| Italiano, D | 1 |
| Finsterer, J | 1 |
| Höftberger, R | 1 |
| Rolinski, B | 1 |
| Stöllberger, C | 1 |
| Wöhrer, A | 1 |
| Winkler, WB | 1 |
| Rheims, S | 1 |
| Ryvlin, P | 1 |
| Barik, KL | 1 |
| Paul, UK | 1 |
| Bhattacharyya, AK | 1 |
| Adhikary, A | 1 |
| Agarwal, G | 1 |
| Rana, KS | 1 |
| Breuer, L | 1 |
| Kasper, BS | 1 |
| Schwarze, B | 1 |
| Gschossmann, JM | 1 |
| Kornhuber, J | 1 |
| Müller, HH | 1 |
| Belcastro, V | 1 |
| Costa, C | 1 |
| Galletti, F | 1 |
| Rossi, A | 1 |
| Tambasco, N | 1 |
| Striano, P | 1 |
| Huang, CW | 1 |
| Pai, MC | 1 |
| Tsai, JJ | 1 |
| Patel, NC | 1 |
| Davenport, RD | 1 |
| Patel, HN | 1 |
| Arcieri, S | 1 |
| D'Aniello, A | 1 |
| Messana, T | 1 |
| Signoriello, G | 1 |
| Pascotto, A | 1 |
| Caraballo, RH | 1 |
| Cersósimo, R | 1 |
| De los Santos, C | 1 |
| Boido, D | 1 |
| Farisello, P | 1 |
| Cesca, F | 1 |
| Ferrea, E | 1 |
| Valtorta, F | 1 |
| Benfenati, F | 1 |
| Baldelli, P | 1 |
| Aggarwal, A | 1 |
| Sharma, DD | 1 |
| Sharma, RC | 1 |
| Kumar, R | 1 |
| Linden, K | 1 |
| Moser, O | 1 |
| Simon, A | 1 |
| Eis-Hübinger, AM | 1 |
| Fleischhack, G | 1 |
| Born, M | 1 |
| Tschampa, H | 1 |
| Rosenbaum, T | 1 |
| Köster, B | 1 |
| Lentze, M | 1 |
| Dubrey, SW | 1 |
| Abdel-Gadir, A | 1 |
| Rakowicz, WP | 1 |
| Sponsler, JL | 1 |
| Kendrick-Adey, AC | 1 |
| Mawhinney, E | 1 |
| Craig, J | 1 |
| Morrow, J | 1 |
| Russell, A | 1 |
| Smithson, WH | 1 |
| Parsons, L | 1 |
| Morrison, PJ | 1 |
| Liggan, B | 1 |
| Irwin, B | 1 |
| Delanty, N | 1 |
| Hunt, SJ | 1 |
| Leppik, IE | 1 |
| Biton, V | 1 |
| Sander, JW | 1 |
| Wieser, HG | 1 |
| De Los Reyes, EC | 1 |
| Sharp, GB | 1 |
| Williams, JP | 1 |
| Hale, SE | 1 |
| Bilo, L | 1 |
| Meo, R | 1 |
| Fulvia de Leva, M | 1 |
| Vinogradova, LV | 1 |
| van Rijn, CM | 1 |
| Gower, AJ | 1 |
| Hirsch, E | 1 |
| Boehrer, A | 1 |
| Noyer, M | 1 |
| Marescaux, C | 1 |
3 reviews available for piracetam and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Anticonvulsant drugs for generalized tonic-clonic epilepsy.
Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Fructose; Humans | 2017 |
Pharmacotherapy for tonic-clonic seizures.
Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Lacosa | 2014 |
Levetiracetam and partial seizure subtypes: pooled data from three randomized, placebo-controlled trials.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combina | 2003 |
2 trials available for piracetam and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
New onset paediatric epilepsy in 1-5 years age group children--approach to management in a tertiary care centre with newer anti-epileptic levetiracetam.
Topics: Age Factors; Anticonvulsants; Child, Preschool; Drug Therapy, Combination; Epilepsies, Partial; Epil | 2014 |
Comparative cognitive effects of levetiracetam and topiramate in intractable epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Cognition Disorders; Drug Therapy, Combination; Epilepsies, Part | 2008 |
17 other studies available for piracetam and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Can zinc depletion play a role in LEV-induced hair loss? Considerations from a case study.
Topics: Adult; Anticonvulsants; Epilepsy, Tonic-Clonic; Female; Hair Diseases; Hematologic Tests; Humans; Le | 2013 |
Presumed mitochondrial disease manifesting with recurrent syncopes.
Topics: Aged; Anticonvulsants; Autonomic Nervous System Diseases; Biopsy; Catheter Ablation; Electrocardiogr | 2014 |
"Herbal seizures"--atypical symptoms after ibogaine intoxication: a case report.
Topics: Adult; Anticonvulsants; Epilepsy, Tonic-Clonic; Hallucinogens; Humans; Hypnotics and Sedatives; Ibog | 2015 |
Rapid effect of levetiracetam in a case of juvenile myoclonic epilepsy.
Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Levetiraceta | 2009 |
Treatment of seizures in a patient with Batten's disease.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Isoxazoles; Levet | 2008 |
Levetiracetam in submaximal subcutaneous pentylentetrazol-induced seizures in rats.
Topics: Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Electroshock; Epilepsy, Gen | 2010 |
Levetiracetam-induced seizure aggravation associated with continuous spikes and waves during slow sleep in children with refractory epilepsies.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Ep | 2010 |
Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam.
Topics: 4-Aminopyridine; Aging; Analysis of Variance; Animals; Anticonvulsants; Cerebral Cortex; Disease Mod | 2010 |
Probable psychosis associated with levetiracetam: a case report.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Levetiracetam; Male; Piracetam | 2011 |
[Transient splenial lesion in influenza A H1N1 2009 infection].
Topics: Acyclovir; Anticonvulsants; Antiviral Agents; Child; Corpus Callosum; Diffusion Magnetic Resonance I | 2011 |
Childhood febrile convulsions and déjà vu in adulthood.
Topics: Adult; Anticonvulsants; Deja Vu; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Le | 2011 |
Seizures as a manifestation of multiple sclerosis.
Topics: Adult; Anticonvulsants; Brain; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Levet | 2011 |
Levetiracetam in pregnancy: results from the UK and Ireland epilepsy and pregnancy registers.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Generalize | 2013 |
Levetiracetam in the treatment of Lennox-Gastaut syndrome.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Generaliz | 2004 |
Levetiracetam in idiopathic generalised epilepsy and porphyria cutanea tarda.
Topics: Administration, Oral; Anticonvulsants; Clonazepam; Drug Therapy, Combination; Epilepsy, Tonic-Clonic | 2006 |
Anticonvulsive and antiepileptogenic effects of levetiracetam in the audiogenic kindling model.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy, Tonic-Cl | 2008 |
Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Epilepsies | 1995 |