piracetam has been researched along with Epilepsy, Temporal Lobe in 26 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levetiracetam (LEV), a newer antiepileptic drug (AED) useful for several epilepsy syndromes, binds to SV2A." | 7.75 | No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy. ( Cavalleri, GL; Delanty, N; Depondt, C; Doherty, CP; Goldstein, DB; Kinirons, P; Lynch, JM; Murphy, K; O'Rourke, D; Sander, JW; Shianna, KV; Sisodiya, SM; Tate, SK; Weale, ME; Wood, NW, 2009) |
| "In a univariate analysis, seizure frequency during the year before suicide, use of antiepileptic drug polytherapy, lack of aura before seizure, diagnosis of temporal lobe epilepsy, use of levetiracetam, psychiatric comorbidity, and use of antidepressants were all significantly higher in the suicide group than in the nonsuicide group." | 3.81 | Identifying clinical correlates for suicide among epilepsy patients in South Korea: A case-control study. ( Ahn, MH; Choi, EJ; Hong, JP; Kang, JK; Lee, HB; Lee, HJ; Park, S; Park, SJ; Ryu, HU, 2015) |
| " We previously showed that tolerance to levetiracetam (LEV) developed within 4 days after the start of the treatment in a rat model for spontaneous seizures after electrically induced status epilepticus." | 3.76 | Improved seizure control by alternating therapy of levetiracetam and valproate in epileptic rats. ( Edelbroek, PM; Gorter, JA; van Vliet, EA, 2010) |
| " Levetiracetam, 40 mg/kg, suppressed the development of kindling measured as severity of seizures and AD duration." | 3.76 | Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats. ( Christensen, KV; Egebjerg, J; Kallunki, P; Leffers, H; Sánchez, C; Watson, WP, 2010) |
| "Levetiracetam (LEV), a newer antiepileptic drug (AED) useful for several epilepsy syndromes, binds to SV2A." | 3.75 | No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy. ( Cavalleri, GL; Delanty, N; Depondt, C; Doherty, CP; Goldstein, DB; Kinirons, P; Lynch, JM; Murphy, K; O'Rourke, D; Sander, JW; Shianna, KV; Sisodiya, SM; Tate, SK; Weale, ME; Wood, NW, 2009) |
| " The non-habitual seizures completely disappeared, and the frequency of the habitual seizures improved to the baseline level after the LEV dosage was reduced." | 1.72 | Seizure Deterioration with Increased Levetiracetam Blood Concentration during the Postpartum Period in Refractory Temporal Lobe Epilepsy. ( Aoki, S; Iida, K; Kikumoto, M; Maruyama, H; Neshige, S; Shishido, T; Ueno, H, 2022) |
| "Levetiracetam (LEV) is a novel anti-epileptic drug (AED) used to treat partial seizures and idiopathic generalized epilepsy." | 1.43 | Chronic treatment with levetiracetam reverses deficits in hippocampal LTP in vivo in experimental temporal lobe epilepsy rats. ( Ge, YX; Lin, YY; Liu, XY; Tian, XZ, 2016) |
| "Temporal lobe epilepsy is considered to be the most frequent of all epileptic syndromes." | 1.42 | Levetiracetam effect on adult-onset temporal lobe epilepsy with positive voltage-gated potassium channel antibody. ( Chen, L; Wang, W; Xiao, J; Zheng, HB; Zhou, D, 2015) |
| "In a first step, we examined anti-seizure effects of 6 AEDs on spontaneous recurrent focal electrographic seizures and secondarily generalized convulsive seizures in epileptic mice, showing that the focal nonconvulsive seizures were resistant to carbamazepine and phenytoin, whereas valproate and levetiracetam exerted moderate and phenobarbital and diazepam marked anti-seizure effects." | 1.42 | Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice. ( Bankstahl, M; Klein, S; Löscher, W, 2015) |
| "Only 29% of LEV-treated animals had seizures compared to all controls following a latent period that was similar in duration." | 1.42 | The anti-ictogenic effects of levetiracetam are mirrored by interictal spiking and high-frequency oscillation changes in a model of temporal lobe epilepsy. ( Avoli, M; Behr, C; Lévesque, M, 2015) |
| "Levetiracetam (LEV) is an interesting novel antiepileptic drug with proven efficacy in both animal models and patients with partial epilepsy." | 1.31 | Development of tolerance during chronic treatment of kindled rats with the novel antiepileptic drug levetiracetam. ( Hönack, D; Löscher, W, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 14 (53.85) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Kikumoto, M | 1 |
| Neshige, S | 1 |
| Shishido, T | 1 |
| Ueno, H | 1 |
| Aoki, S | 1 |
| Iida, K | 1 |
| Maruyama, H | 1 |
| Wandschneider, B | 1 |
| Stretton, J | 1 |
| Sidhu, M | 1 |
| Centeno, M | 1 |
| Kozák, LR | 1 |
| Symms, M | 1 |
| Thompson, PJ | 1 |
| Duncan, JS | 1 |
| Koepp, MJ | 1 |
| Cendes, F | 1 |
| Woermann, FG | 1 |
| Shihabuddin, BS | 1 |
| Herlopian, AS | 1 |
| Greenfield, LJ | 1 |
| Wang, W | 1 |
| Zheng, HB | 1 |
| Xiao, J | 1 |
| Chen, L | 1 |
| Zhou, D | 1 |
| Klein, S | 1 |
| Bankstahl, M | 1 |
| Löscher, W | 3 |
| Lévesque, M | 1 |
| Behr, C | 1 |
| Avoli, M | 1 |
| Palleria, C | 1 |
| Coppola, A | 1 |
| Citraro, R | 1 |
| Del Gaudio, L | 1 |
| Striano, S | 1 |
| De Sarro, G | 1 |
| Russo, E | 1 |
| Park, SJ | 1 |
| Lee, HB | 1 |
| Ahn, MH | 1 |
| Park, S | 1 |
| Choi, EJ | 1 |
| Lee, HJ | 1 |
| Ryu, HU | 1 |
| Kang, JK | 1 |
| Hong, JP | 1 |
| Ge, YX | 1 |
| Tian, XZ | 1 |
| Lin, YY | 1 |
| Liu, XY | 1 |
| van Vliet, EA | 3 |
| Aronica, E | 1 |
| Redeker, S | 1 |
| Boer, K | 1 |
| Gorter, JA | 3 |
| Lynch, JM | 1 |
| Tate, SK | 1 |
| Kinirons, P | 1 |
| Weale, ME | 1 |
| Cavalleri, GL | 1 |
| Depondt, C | 1 |
| Murphy, K | 1 |
| O'Rourke, D | 1 |
| Doherty, CP | 1 |
| Shianna, KV | 1 |
| Wood, NW | 1 |
| Sander, JW | 2 |
| Delanty, N | 1 |
| Goldstein, DB | 1 |
| Sisodiya, SM | 1 |
| Edelbroek, PM | 2 |
| Christensen, KV | 1 |
| Leffers, H | 1 |
| Watson, WP | 1 |
| Sánchez, C | 1 |
| Kallunki, P | 1 |
| Egebjerg, J | 1 |
| Malur, C | 1 |
| Clark, A | 1 |
| Dubrey, SW | 1 |
| Abdel-Gadir, A | 1 |
| Rakowicz, WP | 1 |
| Halliday, AJ | 1 |
| Campbell, TE | 1 |
| Nelson, TS | 1 |
| McLean, KJ | 1 |
| Wallace, GG | 1 |
| Cook, MJ | 1 |
| Klitgaard, H | 1 |
| Matagne, A | 1 |
| Grimee, R | 1 |
| Vanneste-Goemaere, J | 1 |
| Margineanu, DG | 1 |
| Harden, C | 1 |
| MacLusky, NJ | 1 |
| Dove, GH | 1 |
| Buchhalter, JR | 1 |
| Cascino, GD | 1 |
| Mula, M | 1 |
| Trimble, MR | 1 |
| Palma, E | 1 |
| Ragozzino, D | 1 |
| Di Angelantonio, S | 1 |
| Mascia, A | 1 |
| Maiolino, F | 1 |
| Manfredi, M | 1 |
| Cantore, G | 1 |
| Esposito, V | 1 |
| Di Gennaro, G | 1 |
| Quarato, P | 1 |
| Miledi, R | 1 |
| Eusebi, F | 1 |
| van Schaik, R | 1 |
| da Silva, FH | 1 |
| Wadman, WJ | 1 |
| Hönack, D | 1 |
| Glien, M | 1 |
| Brandt, C | 1 |
| Potschka, H | 1 |
| Sandyk, R | 1 |
| Gillman, MA | 1 |
1 review available for piracetam and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Perspectives on treatment options for mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Acetamides; Anticonvulsants; Carbamates; Clinical Trials as Topic; Dibenzazepines; Epilepsy, Tempora | 2015 |
25 other studies available for piracetam and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Seizure Deterioration with Increased Levetiracetam Blood Concentration during the Postpartum Period in Refractory Temporal Lobe Epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Levetiracetam; Piracetam; Postpartu | 2022 |
Levetiracetam reduces abnormal network activations in temporal lobe epilepsy.
Topics: Adult; Anticonvulsants; Brain; Chi-Square Distribution; Epilepsy, Temporal Lobe; Female; Humans; Ima | 2014 |
Going beyond seizure control: can pharmacotherapy help to restore cognitive network function?
Topics: Anticonvulsants; Brain; Epilepsy, Temporal Lobe; Female; Humans; Levetiracetam; Male; Piracetam | 2014 |
Ictal asystole in epilepsy patients undergoing inpatient video-EEG monitoring.
Topics: Aged; Anticonvulsants; Bradycardia; Electroencephalography; Epilepsy, Temporal Lobe; Female; Heart A | 2014 |
Levetiracetam effect on adult-onset temporal lobe epilepsy with positive voltage-gated potassium channel antibody.
Topics: Antibodies; Anticonvulsants; Brain; Epilepsy, Temporal Lobe; Female; Humans; Levetiracetam; Middle A | 2015 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrod | 2015 |
The anti-ictogenic effects of levetiracetam are mirrored by interictal spiking and high-frequency oscillation changes in a model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epi | 2015 |
Identifying clinical correlates for suicide among epilepsy patients in South Korea: A case-control study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Antidepressive Agents; Case-Control Studies; Epilepsy; Epi | 2015 |
Chronic treatment with levetiracetam reverses deficits in hippocampal LTP in vivo in experimental temporal lobe epilepsy rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Levetiraceta | 2016 |
Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Blotting, Western; Child; Disease Models, Animal; Epile | 2009 |
No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.
Topics: Adult; Anticonvulsants; Cohort Studies; Epilepsy; Epilepsy, Temporal Lobe; Female; Genetic Predispos | 2009 |
Improved seizure control by alternating therapy of levetiracetam and valproate in epileptic rats.
Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Drug Administration Schedule; Drug | 2010 |
Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal | 2010 |
Catatonia after right temporal lobe resection.
Topics: Adult; Anticonvulsants; Catatonia; Epilepsy, Temporal Lobe; Humans; Levetiracetam; Lorazepam; Male; | 2010 |
Childhood febrile convulsions and déjà vu in adulthood.
Topics: Adult; Anticonvulsants; Deja Vu; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Le | 2011 |
Levetiracetam-loaded biodegradable polymer implants in the tetanus toxin model of temporal lobe epilepsy in rats.
Topics: Absorbable Implants; Animals; Anticonvulsants; Disease Models, Animal; Drug Delivery Systems; Electr | 2013 |
Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Aspartic Acid; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe | 2003 |
Aromatase inhibition, testosterone, and seizures.
Topics: Anticonvulsants; Aromatase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; | 2004 |
Acute repetitive pilomotor seizures (goose bumps) in a patient with right mesial temporal sclerosis.
Topics: Acute Disease; Adult; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Levetiracetam | 2004 |
The role of hippocampal sclerosis in antiepileptic drug-related depression in patients with epilepsy: a study on levetiracetam.
Topics: Adult; Anticonvulsants; Cognition Disorders; Depression; Epilepsy, Temporal Lobe; Female; Hippocampu | 2006 |
The antiepileptic drug levetiracetam stabilizes the human epileptic GABAA receptors upon repetitive activation.
Topics: Adult; Aged; Animals; Anticonvulsants; Brain Tissue Transplantation; Cell Membrane; Child; Epilepsy, | 2007 |
Development of tolerance to levetiracetam in rats with chronic epilepsy.
Topics: Animals; Anticonvulsants; Chromatography, Gas; Chronic Disease; Disease Models, Animal; Dose-Respons | 2008 |
Development of tolerance during chronic treatment of kindled rats with the novel antiepileptic drug levetiracetam.
Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug T | 2000 |
Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Epilepsy, Temporal Lobe; Female; Infusion Pumps; Levetiracetam; Muscarinic | 2002 |
Piracetam causes confusion in a patient with temporal lobe epilepsy.
Topics: Adult; Cognition Disorders; Confusion; Epilepsy, Temporal Lobe; Humans; Male; Memory, Short-Term; Pi | 1985 |