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piracetam and Delayed Effects, Prenatal Exposure

piracetam has been researched along with Delayed Effects, Prenatal Exposure in 15 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Research Excerpts

ExcerptRelevanceReference
"It is not known whether the antiepileptic drug (AED) levetiracetam can be used safely in human pregnancy."7.73Levetiracetam in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register. ( Craig, J; Guthrie, E; Hunt, S; Irwin, B; Morrison, PJ; Morrow, J; Parsons, L; Robertson, I; Russell, A; Waddell, R, 2006)
"LCM and LEV were both effective against seizures induced by PTZ."5.46Treatment with lacosamide impedes generalized seizures in a rodent model of cortical dysplasia. ( Alexopoulos, AV; Gonzalez-Martinez, J; Najm, IM; Nemes, AD; O'Dwyer, R; Ying, Z, 2017)
" Children exposed to monotherapy levetiracetam (n = 42), topiramate (n = 27), or valproate (n = 47) and a group of children born to women who had untreated epilepsy (n = 55) were enrolled retrospectively from the UK Epilepsy and Pregnancy Register."3.83Cognition in school-age children exposed to levetiracetam, topiramate, or sodium valproate. ( Baker, GA; Bromley, RL; Calderbank, R; Cheyne, CP; Clayton-Smith, J; García-Fiñana, M; Irwin, B; Morrow, JI; Rooney, C; Shallcross, R; Trayner, P, 2016)
"To compare the cognitive and language development of children born to women with epilepsy (WWE) exposed in utero to levetiracetam (LEV) or sodium valproate (VPA) and control children born to women without epilepsy not taking medication during pregnancy."3.80In utero exposure to levetiracetam vs valproate: development and language at 3 years of age. ( Baker, GA; Bromley, RL; Cheyne, CP; García-Fiñana, M; Irwin, B; Morrow, J; Shallcross, R, 2014)
"Children born to women with epilepsy (WWE), exposed in utero to levetiracetam (LEV, n = 51), were assessed for early cognitive development and compared to children exposed to sodium valproate in utero (VPA, n = 44) and a group of children representative of the general population (n = 97)."3.77Child development following in utero exposure: levetiracetam vs sodium valproate. ( Baker, GA; Bonnett, LJ; Bromley, RL; Irwin, B; Morrow, J; Shallcross, R, 2011)
"We aimed to establish the physical, motor, and cognitive teratogenic effect of levetiracetam exposure throughout pregnancy in rats."3.76Effect of prenatal levetiracetam exposure on motor and cognitive functions of rat offspring. ( Bas, DB; Bilge, S; Bozkurt, A; Ciftcioglu, E; Ilkaya, F; Ozyurek, H, 2010)
"It is not known whether the antiepileptic drug (AED) levetiracetam can be used safely in human pregnancy."3.73Levetiracetam in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register. ( Craig, J; Guthrie, E; Hunt, S; Irwin, B; Morrison, PJ; Morrow, J; Parsons, L; Robertson, I; Russell, A; Waddell, R, 2006)
"The current evidence suggests that the overall risk of major malformation after first trimester exposure to Levetiracetam is within the population baseline risk of 1-3%, with no apparent adverse effects on long term child development."2.50The fetal safety of Levetiracetam: a systematic review. ( Chaudhry, SA; Jong, G; Koren, G, 2014)
"LCM and LEV were both effective against seizures induced by PTZ."1.46Treatment with lacosamide impedes generalized seizures in a rodent model of cortical dysplasia. ( Alexopoulos, AV; Gonzalez-Martinez, J; Najm, IM; Nemes, AD; O'Dwyer, R; Ying, Z, 2017)
"Aniracetam was administered to 1-month-old rats, demonstrating a prolonged (2 months) therapeutic effect, observed in rats aged 3 months."1.31Can nootropic drugs be effective against the impact of ethanol teratogenicity on cognitive performance? ( Vaglenova, J; Vesselinov Petkov, V, 2001)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's4 (26.67)29.6817
2010's8 (53.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nemes, AD1
O'Dwyer, R1
Najm, IM1
Ying, Z1
Gonzalez-Martinez, J1
Alexopoulos, AV1
Klein, P1
Mathews, GC1
Shallcross, R3
Bromley, RL3
Cheyne, CP2
García-Fiñana, M2
Irwin, B4
Morrow, J3
Baker, GA3
Chaudhry, SA1
Jong, G1
Koren, G1
Janszky, J1
Calderbank, R1
Rooney, C1
Trayner, P1
Clayton-Smith, J1
Morrow, JI1
Ozyurek, H1
Bozkurt, A1
Bilge, S1
Ciftcioglu, E1
Ilkaya, F1
Bas, DB1
Bonnett, LJ1
Long, L1
Isoherranen, N1
Spiegelstein, O1
Bialer, M1
Zhang, J1
Merriweather, M1
Yagen, B1
Roeder, M1
Triplett, AA1
Schurig, V1
Finnell, RH1
Hunt, S1
Craig, J1
Russell, A1
Guthrie, E1
Parsons, L1
Robertson, I1
Waddell, R1
Morrison, PJ1
Trofimov, SS3
Ostrovskaia, RU3
Kravchenko, EV2
Smol'nikova, NM2
Bondarenko, NA1
Kutepova, OA1
Nemova, EP2
Voronina, TA2
Chepkova, AN1
Smoĺnikova, NI1
Gudasheva, TA1
Vaglenova, J1
Vesselinov Petkov, V1

Reviews

1 review available for piracetam and Delayed Effects, Prenatal Exposure

ArticleYear
The fetal safety of Levetiracetam: a systematic review.
    Reproductive toxicology (Elmsford, N.Y.), 2014, Volume: 46

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Female; Fetal Diseases; Fetus; Humans; Leveti

2014

Other Studies

14 other studies available for piracetam and Delayed Effects, Prenatal Exposure

ArticleYear
Treatment with lacosamide impedes generalized seizures in a rodent model of cortical dysplasia.
    Epilepsia, 2017, Volume: 58, Issue:10

    Topics: Acetamides; Animals; Anticonvulsants; Electroencephalography; Female; GABA Antagonists; Lacosamide;

2017
Antiepileptic drugs and neurocognitive development.
    Neurology, 2014, Jan-21, Volume: 82, Issue:3

    Topics: Anticonvulsants; Child Development; Female; Humans; Language Development; Levetiracetam; Male; Pirac

2014
In utero exposure to levetiracetam vs valproate: development and language at 3 years of age.
    Neurology, 2014, Jan-21, Volume: 82, Issue:3

    Topics: Adult; Anticonvulsants; Child Development; Child, Preschool; Epilepsy; Female; Humans; Language Deve

2014
[Position Statement of Hungarian Epilepsy League: The use of valproate preparations for epilepsy in pregnancy and in women of childbearing age].
    Ideggyogyaszati szemle, 2015, Mar-30, Volume: 68, Issue:3-4

    Topics: Adolescent; Adult; Anticonvulsants; Cognition; Contraception; Dose-Response Relationship, Drug; Drug

2015
Cognition in school-age children exposed to levetiracetam, topiramate, or sodium valproate.
    Neurology, 2016, Nov-01, Volume: 87, Issue:18

    Topics: Adult; Anticonvulsants; Child; Cognition Disorders; Cross-Sectional Studies; Epilepsy; Female; Follo

2016
Effect of prenatal levetiracetam exposure on motor and cognitive functions of rat offspring.
    Brain & development, 2010, Volume: 32, Issue:5

    Topics: Animals; Anticonvulsants; Avoidance Learning; Cognition; Exploratory Behavior; Female; Learning; Lev

2010
Child development following in utero exposure: levetiracetam vs sodium valproate.
    Neurology, 2011, Jan-25, Volume: 76, Issue:4

    Topics: Anticonvulsants; Child Development; Child, Preschool; Cognition; Epilepsy; Female; Humans; Infant; L

2011
Levetiracetam monotherapy during pregnancy: a case series.
    Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:4

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Humans; Infant, Newborn; Levetiracet

2003
Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity.
    Epilepsia, 2003, Volume: 44, Issue:10

    Topics: Animals; Butyrates; Disease Models, Animal; Female; Fetus; Levetiracetam; Mice; Piracetam; Pregnancy

2003
Levetiracetam in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register.
    Neurology, 2006, Nov-28, Volume: 67, Issue:10

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Body Weight; Epilepsy; Female; Humans; Infant,

2006
[Behavior disorders in rats exposed to intrauterine hypoxia, and their correction by postnatal treatment with piracetam].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:1

    Topics: Animals; Behavior, Animal; Female; Fetal Hypoxia; Learning Disabilities; Memory Disorders; Piracetam

1993
[Piracetam as a corrector of long-term learning disorders caused by prenatal alcohol exposure: the significance of the length of therapy].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 121, Issue:4

    Topics: Animals; Avoidance Learning; Ethanol; Female; Learning Disabilities; Male; Nootropic Agents; Piracet

1996
[Damage to plastic properties of synaptic transmission in the rat hippocampus resulting from prenatal hypoxia, and their normalization by treatment with nootropic dipeptides].
    Biulleten' eksperimental'noi biologii i meditsiny, 1995, Volume: 120, Issue:12

    Topics: Animals; Dipeptides; Female; Hippocampus; Hypoxia; Male; Neuronal Plasticity; Nootropic Agents; Pira

1995
Can nootropic drugs be effective against the impact of ethanol teratogenicity on cognitive performance?
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2001, Volume: 11, Issue:1

    Topics: Alcohol-Induced Disorders, Nervous System; Animals; Disease Models, Animal; Female; Learning Disabil

2001