piracetam has been researched along with Concussive Convulsion in 12 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levetiracetam was safe and well tolerated in this population." | 2.78 | Results of phase II levetiracetam trial following acute head injury in children at risk for posttraumatic epilepsy. ( Atabaki, SM; He, J; Klein, P; McCarter, R; McGavin, CL; Pearl, PL; Sandoval, F; Trzcinski, S; Tsuchida, T; van den Anker, J; Yu, Y, 2013) |
| "Seizures were induced at two weeks after FPI by KA in another group (FPI-LS)." | 1.43 | Levetiracetam prophylaxis ameliorates seizure epileptogenesis after fluid percussion injury. ( Chen, YH; Chiang, YH; Chou, YC; Hoffer, BJ; Huang, EY; Kuo, TT; Ma, HI; Tsai, JJ; Wu, PJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Amin, TA | 1 |
| Nerenberg, SF | 1 |
| Elsawy, OA | 1 |
| Wang, A | 1 |
| Johnston, JP | 1 |
| Wilson, CD | 1 |
| Burks, JD | 1 |
| Rodgers, RB | 1 |
| Evans, RM | 1 |
| Bakare, AA | 1 |
| Safavi-Abbasi, S | 1 |
| Bakr, A | 1 |
| Belli, A | 1 |
| Pearl, PL | 1 |
| McCarter, R | 1 |
| McGavin, CL | 1 |
| Yu, Y | 1 |
| Sandoval, F | 1 |
| Trzcinski, S | 1 |
| Atabaki, SM | 1 |
| Tsuchida, T | 1 |
| van den Anker, J | 1 |
| He, J | 1 |
| Klein, P | 1 |
| Savenkov, AA | 1 |
| Badalian, OL | 1 |
| Avakian, GN | 1 |
| Chen, YH | 1 |
| Huang, EY | 1 |
| Kuo, TT | 1 |
| Hoffer, BJ | 1 |
| Wu, PJ | 1 |
| Ma, HI | 1 |
| Tsai, JJ | 1 |
| Chou, YC | 1 |
| Chiang, YH | 1 |
| Javed, G | 1 |
| Waqas, M | 1 |
| Qadeer, M | 1 |
| Bari, E | 1 |
| Murtaza, G | 1 |
| Jones, KE | 1 |
| Puccio, AM | 1 |
| Harshman, KJ | 1 |
| Falcione, B | 1 |
| Benedict, N | 1 |
| Jankowitz, BT | 1 |
| Stippler, M | 1 |
| Fischer, M | 1 |
| Sauber-Schatz, EK | 1 |
| Fabio, A | 1 |
| Darby, JM | 1 |
| Okonkwo, DO | 1 |
| Poverennova, IE | 1 |
| Iakunina, AV | 1 |
| Kalinin, VA | 1 |
| Kurov, MV | 1 |
| Schauer, R | 1 |
| Singer, M | 1 |
| Saltuari, L | 1 |
| Kofler, M | 1 |
| Lekomtsev, VT | 1 |
| Sharova, EV | 1 |
| Potapov, AA | 1 |
| Kulikov, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot: Levetiracetam to Prevent Post-Traumatic Epilepsy[NCT01463033] | Phase 2 | 126 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
| A Pharmacokinetic Analysis of Levetiracetam Prophylaxis in Critically Ill Patients With Severe Traumatic Brain Injury[NCT04836481] | 20 participants (Anticipated) | Observational | 2021-01-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
occurrence of PTE (Post-Traumatic Epilepsy) (NCT01463033)
Timeframe: 2 years
| Intervention | participants (Number) |
|---|---|
| Levetiracetam | 6 |
| Observational | 8 |
The 66 subjects with acute head injury with a high risk for developing post-traumatic epilepsy that received levetiracetam 55 mg/kg/day in a b.i.d. were monitored for adverse events through the 30 day treatment period. (NCT01463033)
Timeframe: 30 day treatment period
| Intervention | Events (Number) | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Headache | Fatigue | Drowsiness | Memory Impairment | Amnesia | Pain | Irritability | Dizziness | Anorexia | Emotional lability | Insomnia | Cognitive changes | Ataxia | Depression | Hostility | Vertigo | Nausea | Cough | Nervousness | Paraesthesia | Weight gain | Hallucinations | Other | Diplopia | Suicidality | Psychosis | |
| Participants | 28 | 28 | 20 | 9 | 8 | 15 | 10 | 10 | 6 | 7 | 5 | 7 | 6 | 7 | 3 | 1 | 2 | 2 | 5 | 3 | 1 | 5 | 2 | 3 | 3 | 3 |
2 reviews available for piracetam and Concussive Convulsion
| Article | Year |
|---|---|
Early and Late Posttraumatic Epilepsy in the Setting of Traumatic Brain Injury: A Meta-analysis and Review of Antiepileptic Management.
Topics: Anticonvulsants; Brain Injuries, Traumatic; Epilepsy, Post-Traumatic; Humans; Levetiracetam; Phenyto | 2018 |
A systematic review of levetiracetam versus phenytoin in the prevention of late post-traumatic seizures and survey of UK neurosurgical prescribing practice of antiepileptic medication in acute traumatic brain injury.
Topics: Adult; Anticonvulsants; Brain Injuries, Traumatic; Cohort Studies; Epilepsy, Post-Traumatic; Female; | 2018 |
2 trials available for piracetam and Concussive Convulsion
| Article | Year |
|---|---|
Results of phase II levetiracetam trial following acute head injury in children at risk for posttraumatic epilepsy.
Topics: Adolescent; Anticonvulsants; Brain Injuries; Child; Craniocerebral Trauma; Epilepsy, Post-Traumatic; | 2013 |
[Nootropics and antioxidants in the complex therapy of symptomatic posttraumatic epilepsy].
Topics: Adolescent; Adult; Antioxidants; Cognition; Drug Therapy, Combination; Electroencephalography; Epile | 2013 |
8 other studies available for piracetam and Concussive Convulsion
| Article | Year |
|---|---|
Evaluation of levetiracetam for early post-traumatic seizure prophylaxis: A level II trauma center experience.
Topics: Adult; Aged; Anticonvulsants; Epilepsy, Post-Traumatic; Female; Humans; Levetiracetam; Male; Middle | 2023 |
Levetiracetam prophylaxis ameliorates seizure epileptogenesis after fluid percussion injury.
Topics: Animals; Anticonvulsants; Brain Injuries, Traumatic; CA1 Region, Hippocampal; Disease Models, Animal | 2016 |
Use of Levetiracetam in Prophylaxis of Early Post-Traumatic Seizures.
Topics: Anticonvulsants; Epilepsy, Post-Traumatic; Humans; Levetiracetam; Outcome Assessment, Health Care; P | 2016 |
Levetiracetam versus phenytoin for seizure prophylaxis in severe traumatic brain injury.
Topics: Adult; Brain Injuries; Cohort Studies; Electroencephalography; Epilepsy, Post-Traumatic; Female; Hum | 2008 |
[Phenotropil in the complex treatment of symptomatic post traumatic epilepsy].
Topics: Adult; Combined Modality Therapy; Epilepsies, Partial; Epilepsy, Post-Traumatic; Female; Humans; Mal | 2011 |
Suppression of cortical myoclonus by levetiracetam.
Topics: Adolescent; Anticonvulsants; Cerebral Cortex; Dominance, Cerebral; Drug Therapy, Combination; Epilep | 2002 |
[Nootropic agents in the complex treatment of patients with traumatic epilepsy].
Topics: Adult; Brain Injuries; Consciousness Disorders; Drug Therapy, Combination; Epilepsy, Post-Traumatic; | 1990 |
[Effect of piracetam on the functional activity of the brain in patients with craniocerebral injuries].
Topics: Brain; Brain Injuries; Drug Evaluation; Electroencephalography; Epilepsy, Post-Traumatic; Humans; Pi | 1988 |