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piracetam and Complication, Postoperative

piracetam has been researched along with Complication, Postoperative in 19 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Research Excerpts

ExcerptRelevanceReference
"Treatment with levetiracetam is efficacious, and levetiracetam-treated patients require significantly lower doses of immunosuppressant medications to achieve an equivalent antirejection effect."6.71Levetiracetam for seizures after liver transplantation. ( Bergethon, PR; Freeman, R; Glass, GA; Mithoefer, A; Stankiewicz, J, 2005)
"To compare the incidence of seizures in patients receiving either prophylactic PHT or LEV perioperatively, 971 patients undergoing a craniotomy were analysed retrospectively during a 2-year period."5.38Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy. ( Brawanski, AT; Feigl, GC; Hansen, E; Kern, K; Lange, M; Schebesch, KM; Schlaier, J, 2012)
"No more seizures occurred in patients receiving 1-3 g LEV preoperatively."5.37Perioperative levetiracetam for prevention of seizures in supratentorial brain tumor surgery. ( Donat, M; Oberndorfer, S; Roessler, K; Zachenhofer, I, 2011)
"On pharmacological treatment of epilepsy in people with intellectual disabilities, there were two articles on topiramate and one on levetiracetam."4.83Update on treatment of epilepsy in people with intellectual disabilities. ( Huber, B; Seidel, M, 2006)
"Both levetiracetam (LEV) and phenytoin (PHT) were associated with a low risk of early postoperative seizures and a moderate risk of later epilepsy."3.74Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery. ( Bromfield, EB; Hurwitz, S; Milligan, TA, 2008)
"Phenytoin (PHT) is routinely used for seizure prophylaxis in patients with brain tumours during and after craniotomy, despite incomplete evidence."2.80Levetiracetam versus phenytoin for seizure prophylaxis during and early after craniotomy for brain tumours: a phase II prospective, randomised study. ( Hasegawa, Y; Iuchi, T; Kawasaki, K; Kuwabara, K; Matsumoto, M; Sakaida, T, 2015)
"Treatment with levetiracetam is efficacious, and levetiracetam-treated patients require significantly lower doses of immunosuppressant medications to achieve an equivalent antirejection effect."2.71Levetiracetam for seizures after liver transplantation. ( Bergethon, PR; Freeman, R; Glass, GA; Mithoefer, A; Stankiewicz, J, 2005)
"The incidence of seizures following supratentorial craniotomy for non-traumatic pathology has been estimated to be between 15% to 20%; however, the risk of experiencing a seizure appears to vary from 3% to 92% over a five-year period."2.66Antiepileptic drugs as prophylaxis for postcraniotomy seizures. ( Dundar, Y; Greenhalgh, J; Marson, AG; Nevitt, SJ; Weston, J, 2020)
"Since surgery is believed to aggravate cerebral hypoxia and the consequent neurological dysfunction, patients undergoing surgery for brain tumours or ruptured cerebral aneurysms were studied."2.64Effect of piracetam on level of consciousness after neurosurgery. ( Bereen, FJ; Richardson, AE, 1977)
"Postoperative seizures can precipitate the development of epilepsy; seizures are most likely to occur within the first month of cranial surgery."2.58Antiepileptic drugs as prophylaxis for postcraniotomy seizures. ( Dundar, Y; Greenhalgh, J; Marson, AG; Nevitt, SJ; Weston, J, 2018)
"To compare the incidence of seizures in patients receiving either prophylactic PHT or LEV perioperatively, 971 patients undergoing a craniotomy were analysed retrospectively during a 2-year period."1.38Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy. ( Brawanski, AT; Feigl, GC; Hansen, E; Kern, K; Lange, M; Schebesch, KM; Schlaier, J, 2012)
"Complete seizure freedom was defined as a favorable outcome."1.38Levetiracetam may favorably affect seizure outcome after temporal lobectomy. ( Bingaman, W; Irwin, AI; Jehi, LE; Kayyali, H; Najm, I; Vadera, S, 2012)
"No more seizures occurred in patients receiving 1-3 g LEV preoperatively."1.37Perioperative levetiracetam for prevention of seizures in supratentorial brain tumor surgery. ( Donat, M; Oberndorfer, S; Roessler, K; Zachenhofer, I, 2011)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's2 (10.53)18.2507
2000's5 (26.32)29.6817
2010's9 (47.37)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Greenhalgh, J2
Weston, J2
Dundar, Y2
Nevitt, SJ2
Marson, AG2
Iuchi, T1
Kuwabara, K1
Matsumoto, M1
Kawasaki, K1
Hasegawa, Y1
Sakaida, T1
Habets, JGV1
Leentjens, AFG1
Schijns, OEMG1
Milligan, TA1
Hurwitz, S1
Bromfield, EB1
Zachenhofer, I1
Donat, M1
Oberndorfer, S1
Roessler, K1
Devarajan, J1
Siyam, AM1
Alexopoulos, AV1
Weil, R1
Farag, E1
Kern, K1
Schebesch, KM1
Schlaier, J1
Hansen, E1
Feigl, GC1
Brawanski, AT1
Lange, M1
Jehi, LE1
Irwin, AI1
Kayyali, H1
Vadera, S1
Bingaman, W1
Najm, I1
Fernández-Torrón, R1
Esteve-Belloch, P1
Palma, JA1
Riverol, M1
Iriarte, J1
Zou, LP1
Ding, CH1
Song, ZJ1
Li, XF1
Motamedi, M1
Nguyen, DK1
Zaatreh, M1
Singh, SP1
Westerveld, M1
Thompson, JL1
Mattson, R1
Blumenfeld, H1
Novotny, E1
Spencer, SS1
Chabolla, DR1
Harnois, DM1
Meschia, JF1
Glass, GA1
Stankiewicz, J1
Mithoefer, A1
Freeman, R1
Bergethon, PR1
Huber, B1
Seidel, M1
Klimenko, VN1
Belenichev, IF1
Bashkin, IN1
Shavrin, VA1
Vizir, VA1
Guĭtur, MM1
Richardson, AE1
Bereen, FJ1
Zaffiri, O1
Marchetti, G1
Vignotto, F1
Bonardi, C1
Scarella, MR1
Gottstein, U1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Levetiracetam Treatment of Neonatal Seizures: A Multi-Centre Randomized Blinded Controlled Study of the Efficacy of Oral Levetiracetam as First Line Treatment for Neonatal Seizures in China[NCT02550028]Phase 1/Phase 260 participants (Actual)Interventional2015-09-01Terminated (stopped due to The study was concluded as planned upon reaching its predetermined endpoint, which included the completion of data collection and achievement of the necessary sample size for statistical significance.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for piracetam and Complication, Postoperative

ArticleYear
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
    The Cochrane database of systematic reviews, 2020, 04-28, Volume: 4

    Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenyt

2020
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
    The Cochrane database of systematic reviews, 2018, 05-23, Volume: 5

    Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenyt

2018
Update on treatment of epilepsy in people with intellectual disabilities.
    Current opinion in psychiatry, 2006, Volume: 19, Issue:5

    Topics: Anticonvulsants; Brain; Electric Stimulation Therapy; Epilepsy; Fructose; Humans; Intellectual Disab

2006

Trials

3 trials available for piracetam and Complication, Postoperative

ArticleYear
Levetiracetam versus phenytoin for seizure prophylaxis during and early after craniotomy for brain tumours: a phase II prospective, randomised study.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Neoplasms; Cohort Studies; Cranio

2015
Levetiracetam for seizures after liver transplantation.
    Neurology, 2005, Mar-22, Volume: 64, Issue:6

    Topics: Anticonvulsants; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions

2005
Effect of piracetam on level of consciousness after neurosurgery.
    Lancet (London, England), 1977, Nov-26, Volume: 2, Issue:8048

    Topics: Brain Neoplasms; Cerebral Cortex; Consciousness; Humans; Hypoxia, Brain; Intracranial Aneurysm; Pira

1977

Other Studies

13 other studies available for piracetam and Complication, Postoperative

ArticleYear
Serious and reversible levetiracetam-induced psychiatric symptoms after resection of frontal low-grade glioma: two case histories.
    British journal of neurosurgery, 2017, Volume: 31, Issue:4

    Topics: Anticonvulsants; Brain Neoplasms; Craniotomy; Epilepsy; Frontal Lobe; Humans; Levetiracetam; Magneti

2017
Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery.
    Neurology, 2008, Aug-26, Volume: 71, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain; Brain Injuries; Drug Tolerance; Drug-Related

2008
Perioperative levetiracetam for prevention of seizures in supratentorial brain tumor surgery.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Female; Humans; Levetiracetam; Male; Middle Aged; N

2011
Non-convulsive status epilepticus in the postanesthesia care unit following meningioma excision.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2011, Volume: 58, Issue:1

    Topics: Aged, 80 and over; Anticonvulsants; Craniotomy; Electroencephalography; Female; Humans; Levetiraceta

2011
Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; Contraindications; Craniotomy; F

2012
Levetiracetam may favorably affect seizure outcome after temporal lobectomy.
    Epilepsia, 2012, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Anterior Temporal Lobectomy; Anticonvulsants; Child; Child, Preschool; Epil

2012
[Prolonged hemiplegia as the only symptom of a simple focal nonconvulsive status epilepticus].
    Revista de neurologia, 2012, Aug-16, Volume: 55, Issue:4

    Topics: Anticonvulsants; Bacteriuria; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Electro

2012
Stevens-Johnson syndrome induced by levetiracetam.
    Seizure, 2012, Volume: 21, Issue:10

    Topics: Anticonvulsants; Cardiovascular Surgical Procedures; Child, Preschool; Female; Heart Defects, Congen

2012
Levetiracetam efficacy in refractory partial-onset seizures, especially after failed epilepsy surgery.
    Epilepsia, 2003, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Combined Modality Therapy; Dose-Respons

2003
Levetiracetam monotherapy for liver transplant patients with seizures.
    Transplantation proceedings, 2003, Volume: 35, Issue:4

    Topics: Anticonvulsants; Hepatitis C; Humans; Levetiracetam; Liver Cirrhosis, Alcoholic; Liver Transplantati

2003
[Pharmacologic protection of brain in surgery of the brachiocephalic arteries].
    Klinicheskaia khirurgiia, 1993, Issue:7-8

    Topics: Animals; Brachiocephalic Trunk; Brain Ischemia; Carotid Arteries; Constriction; Dogs; Endarterectomy

1993
[Personal experience with the use of piracetam (Nootropil) in anesthesiology].
    Minerva anestesiologica, 1977, Volume: 43, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Coma; Confusion; Drug Evaluation; Heart Arrest; Humans;

1977
[Pathophysiology, clinical aspects and therapy of pre- and postoperative disorders of cerebral circulation and function].
    Langenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress, 1990

    Topics: Brain; Cerebrovascular Disorders; Epilepsy; Hemodynamics; Homeostasis; Humans; Neurocognitive Disord

1990