Page last updated: 2024-11-02

piracetam and Coma

piracetam has been researched along with Coma in 8 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Research Excerpts

ExcerptRelevanceReference
"Levetiracetam is an anti-epileptic drug commonly used in intensive care when seizure is suspected as a possible cause of coma."7.85Marked EEG worsening following Levetiracetam overdose: How a pharmacological issue can confound coma prognosis. ( André-Obadia, N; Bouchier, B; Demarquay, G; Gobert, F; Guérin, C, 2017)
"Levetiracetam is an anti-epileptic drug commonly used in intensive care when seizure is suspected as a possible cause of coma."3.85Marked EEG worsening following Levetiracetam overdose: How a pharmacological issue can confound coma prognosis. ( André-Obadia, N; Bouchier, B; Demarquay, G; Gobert, F; Guérin, C, 2017)
"We propose that a combination of levetiracetam and amantadine may provide neuroprotective and neurorestorative properties when administered during a period of hyperpyrexia accompanied by any form of mental status changes, particularly if there is a decline in Glasgow Coma Score."3.85Preserving brain function in a comatose patient with septic hyperpyrexia (41.6 °C): a case report. ( Akinyemi, A; Michel, G; Sanchez-Gonzalez, MA; Sterkel, S, 2017)
"Posthypoxic coma is often associated with cortical and brainstem hyperexcitability."1.33Levetiracetam suppresses long-loop reflexes at the cortical level. ( Kofler, M, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouchier, B1
Demarquay, G1
Guérin, C1
André-Obadia, N1
Gobert, F1
Sterkel, S1
Akinyemi, A1
Sanchez-Gonzalez, MA1
Michel, G1
Kofler, M1
Polívková, J1
Koudela, J1
Martí Viaño, JL1
Sellés, J1
Orts, A1
Marco, J1
Vega, F1
Esplugues, J1
Calliauw, L1
Marchau, M1
Zaffiri, O1
Marchetti, G1
Vignotto, F1
Bonardi, C1
Scarella, MR1
Roquefeuil, B1
Escuret, E1
Viguié, E1

Trials

2 trials available for piracetam and Coma

ArticleYear
[Clinical trials of piracetam in anesthesiology and resuscitation].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1984, Volume: 63, Issue:1

    Topics: Adult; Anesthesia; Clinical Trials as Topic; Coma; Female; Humans; Middle Aged; Piracetam; Pyrrolidi

1984
Clinical trial of piracetam in disorders of consciousness due to head injury.
    Acta anaesthesiologica Belgica, 1975, Volume: 26, Issue:1

    Topics: Adult; Animals; Blood-Brain Barrier; Clinical Trials as Topic; Coma; Consciousness; Craniocerebral T

1975

Other Studies

6 other studies available for piracetam and Coma

ArticleYear
Marked EEG worsening following Levetiracetam overdose: How a pharmacological issue can confound coma prognosis.
    Clinical neurology and neurosurgery, 2017, Volume: 152

    Topics: Adult; Anticonvulsants; Coma; Drug Overdose; Electroencephalography; Female; Heart Arrest; Humans; H

2017
Preserving brain function in a comatose patient with septic hyperpyrexia (41.6 °C): a case report.
    Journal of medical case reports, 2017, Feb-13, Volume: 11, Issue:1

    Topics: Adult; Amantadine; Anticonvulsants; Brain; Brain Injuries; Cognition Disorders; Coma; Dopamine Agent

2017
Levetiracetam suppresses long-loop reflexes at the cortical level.
    Muscle & nerve, 2006, Volume: 33, Issue:6

    Topics: Coma; Evoked Potentials, Somatosensory; H-Reflex; Humans; Hypoxia, Brain; Levetiracetam; Male; Middl

2006
[Antagonism of barbituric coma by stimulating products. Experimental study].
    Revista espanola de anestesiologia y reanimacion, 1978, Volume: 25, Issue:1

    Topics: Animals; Body Weight; Choline; Coma; Cytidine Diphosphate Choline; Female; Glycolates; Injections, I

1978
[Personal experience with the use of piracetam (Nootropil) in anesthesiology].
    Minerva anestesiologica, 1977, Volume: 43, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Coma; Confusion; Drug Evaluation; Heart Arrest; Humans;

1977
[Metabolic study of piracetam in neurosurgical resuscitation].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1975, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Brain; Coma; Female; Glucose; Humans; Lactates; Male; Middle Aged; Oxygen C

1975