Page last updated: 2024-11-02

piracetam and Aphasia

piracetam has been researched along with Aphasia in 15 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Aphasia: A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.

Research Excerpts

ExcerptRelevanceReference
"In a prospective, double-blind, placebo-controlled study, it was investigated whether piracetam improves language recovery in poststroke aphasia assessed by neuropsychological tests and activation PET measurement of cerebral blood flow."9.09Piracetam improves activated blood flow and facilitates rehabilitation of poststroke aphasic patients. ( Heiss, WD; Karbe, H; Kessler, J; Thiel, A, 2000)
"Electroencephalographic and clinical effects of piracetam in post-stroke aphasia were evaluated in a prospective, randomized, double-blind, placebo-controlled trial."9.09Restitution of alpha-topography by piracetam in post-stroke aphasia. ( Heiss, WD; Kessler, J; Mielke, R; Szelies, B, 2001)
"Piracetam appears to have a positive adjuvant effect on the recovery of aphasia in patients receiving intensive language therapy."9.08Piracetam as an adjuvant to language therapy for aphasia: a randomized double-blind placebo-controlled pilot study. ( Deberdt, W; Huber, W; Poeck, K; Van Vleymen, B; Willmes, K, 1997)
"We performed a systematic review and meta-analysis to assess whether piracetam facilitates the rehabilitation of language performance in post-stroke patients."8.93Piracetam for Aphasia in Post-stroke Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials. ( Chen, Z; Luo, B; Wei, R; Zhang, J, 2016)
"Piracetam has been shown to improve speech in aphasic patients."6.40The role of piracetam in the treatment of acute and chronic aphasia. ( Huber, W, 1999)
"In a prospective, double-blind, placebo-controlled study, it was investigated whether piracetam improves language recovery in poststroke aphasia assessed by neuropsychological tests and activation PET measurement of cerebral blood flow."5.09Piracetam improves activated blood flow and facilitates rehabilitation of poststroke aphasic patients. ( Heiss, WD; Karbe, H; Kessler, J; Thiel, A, 2000)
"Electroencephalographic and clinical effects of piracetam in post-stroke aphasia were evaluated in a prospective, randomized, double-blind, placebo-controlled trial."5.09Restitution of alpha-topography by piracetam in post-stroke aphasia. ( Heiss, WD; Kessler, J; Mielke, R; Szelies, B, 2001)
"Piracetam appears to have a positive adjuvant effect on the recovery of aphasia in patients receiving intensive language therapy."5.08Piracetam as an adjuvant to language therapy for aphasia: a randomized double-blind placebo-controlled pilot study. ( Deberdt, W; Huber, W; Poeck, K; Van Vleymen, B; Willmes, K, 1997)
"We performed a systematic review and meta-analysis to assess whether piracetam facilitates the rehabilitation of language performance in post-stroke patients."4.93Piracetam for Aphasia in Post-stroke Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials. ( Chen, Z; Luo, B; Wei, R; Zhang, J, 2016)
"Pharmacotherapy of aphasia had been discussed for the last twenty years with first bromocriptine and amphetamine and then serotoninergic, GABAergic and cholinergic agents."4.84Pharmacotherapy of aphasia: myth or reality? ( de Boissezon, X; de Boysson, C; Démonet, JF; Peran, P, 2007)
"The main conclusion of this review is that drug treatment with piracetam may be effective in the treatment of aphasia after stroke."4.81Pharmacological treatment for aphasia following stroke. ( Enderby, P; Greener, J; Whurr, R, 2001)
"We report the case of an aborted awake craniotomy for a left frontotemporoinsular glioma due to ammonia encephalopathy on a patient taking Levetiracetam, valproic acid and clobazam."3.81Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy. ( Arroyo Pérez, R; Fernández-Candil, JL; León Jorba, A; Pacreu Terradas, S; Villalba Martínez, G; Vivanco-Hidalgo, RM, 2015)
" However, EEG was abnormal and the boy was diagnosed as a case of Landau-Kleffner syndrome (LKS) and treated with sodium valproate, levetiracetam and steroids."3.81Landau-Kleffner syndrome: an uncommon dealt with case in Southeast Asia. ( Afsar, S; Dixit, NS; Motwani, N; Sharma, N, 2015)
"Piracetam has been shown to improve speech in aphasic patients."2.40The role of piracetam in the treatment of acute and chronic aphasia. ( Huber, W, 1999)
"Aphasia is a language disorder characterised by loss of ability to produce or comprehend written or spoken language."1.48Adult-onset epileptic aphasia. ( Guerra, D; Marques Mendes, E; Mendes, A; Ribeiro, C, 2018)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (33.33)18.2507
2000's5 (33.33)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marques Mendes, E1
Mendes, A1
Ribeiro, C1
Guerra, D1
Villalba Martínez, G1
Fernández-Candil, JL1
Vivanco-Hidalgo, RM1
Pacreu Terradas, S1
León Jorba, A1
Arroyo Pérez, R1
Motwani, N1
Afsar, S1
Dixit, NS1
Sharma, N1
Zhang, J1
Wei, R1
Chen, Z1
Luo, B1
Güngör, L1
Terzi, M1
Onar, MK1
Schmidtke, K1
de Boissezon, X1
Peran, P1
de Boysson, C1
Démonet, JF1
Deberdt, W3
Huber, W2
Willmes, K1
Poeck, K1
Van Vleymen, B1
Enderby, P2
Broeckx, J1
Hospers, W1
Schildermans, F1
Orgogozo, JM1
Kessler, J2
Thiel, A1
Karbe, H1
Heiss, WD2
Szelies, B1
Mielke, R1
Greener, J1
Whurr, R1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Escitalopram and Language Intervention for Subacute Aphasia (ELISA)[NCT03843463]Phase 288 participants (Anticipated)Interventional2021-07-18Recruiting
A Randomized Clinical Trial of tDCS to Remediate Phonological Impairment in Aphasia[NCT06010030]200 participants (Anticipated)Interventional2023-08-25Recruiting
Effects of tDCS in Language Recovery and Reorganization in Chronic Aphasia[NCT04166513]4 participants (Anticipated)Interventional2019-12-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for piracetam and Aphasia

ArticleYear
Piracetam for Aphasia in Post-stroke Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
    CNS drugs, 2016, Volume: 30, Issue:7

    Topics: Aphasia; Humans; Language Disorders; Piracetam; Randomized Controlled Trials as Topic; Stroke; Treat

2016
Pharmacotherapy of aphasia: myth or reality?
    Brain and language, 2007, Volume: 102, Issue:1

    Topics: Amphetamine; Aphasia; Bromocriptine; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil;

2007
The role of piracetam in the treatment of acute and chronic aphasia.
    Pharmacopsychiatry, 1999, Volume: 32 Suppl 1

    Topics: Acute Disease; Aphasia; Cerebrovascular Disorders; Chronic Disease; Humans; Nootropic Agents; Pirace

1999
Pharmacological treatment for aphasia following stroke.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Aphasia; Humans; Neuroprotective Agents; Piracetam; Randomized Controlled Trials as Topic; Stroke

2001
Pharmacological treatment for aphasia following stroke.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Aphasia; Humans; Neuroprotective Agents; Piracetam; Randomized Controlled Trials as Topic; Stroke

2001
Pharmacological treatment for aphasia following stroke.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Aphasia; Humans; Neuroprotective Agents; Piracetam; Randomized Controlled Trials as Topic; Stroke

2001
Pharmacological treatment for aphasia following stroke.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Aphasia; Humans; Neuroprotective Agents; Piracetam; Randomized Controlled Trials as Topic; Stroke

2001

Trials

6 trials available for piracetam and Aphasia

ArticleYear
Does long term use of piracetam improve speech disturbances due to ischemic cerebrovascular diseases?
    Brain and language, 2011, Volume: 117, Issue:1

    Topics: Aphasia; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Piracetam; Single-Blind Method;

2011
Interaction between psychological and pharmacological treatment in cognitive impairment.
    Life sciences, 1994, Volume: 55, Issue:25-26

    Topics: Adolescent; Aged; Aged, 80 and over; Analysis of Variance; Aphasia; Child; Cognition Disorders; Doub

1994
Piracetam as an adjuvant to language therapy for aphasia: a randomized double-blind placebo-controlled pilot study.
    Archives of physical medicine and rehabilitation, 1997, Volume: 78, Issue:3

    Topics: Adult; Aged; Aphasia; Combined Modality Therapy; Data Interpretation, Statistical; Double-Blind Meth

1997
Effect of piracetam on recovery and rehabilitation after stroke: a double-blind, placebo-controlled study.
    Clinical neuropharmacology, 1994, Volume: 17, Issue:4

    Topics: Aged; Aphasia; Cerebral Infarction; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropro

1994
Piracetam improves activated blood flow and facilitates rehabilitation of poststroke aphasic patients.
    Stroke, 2000, Volume: 31, Issue:9

    Topics: Adolescent; Adult; Aged; Aphasia; Brain; Cerebrovascular Circulation; Combined Modality Therapy; Dou

2000
Restitution of alpha-topography by piracetam in post-stroke aphasia.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Aphasia; Brain Mapping; Double-Blind Method; Electroencephalograp

2001

Other Studies

5 other studies available for piracetam and Aphasia

ArticleYear
Adult-onset epileptic aphasia.
    BMJ case reports, 2018, Jun-29, Volume: 2018

    Topics: Aged; Anticonvulsants; Aphasia; Cerebral Cortex; Electroencephalography; Epilepsy; Female; Humans; L

2018
Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy.
    Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:5

    Topics: Anesthesia, General; Anesthesia, Local; Anticonvulsants; Aphasia; Benzodiazepines; Brain Diseases; B

2015
Landau-Kleffner syndrome: an uncommon dealt with case in Southeast Asia.
    BMJ case reports, 2015, Sep-29, Volume: 2015

    Topics: Anticonvulsants; Aphasia; Asia, Southeastern; Child; Electroencephalography; Humans; Landau-Kleffner

2015
[Does treatment with piracetam in stroke patients with aphasia make sense?].
    Deutsche medizinische Wochenschrift (1946), 2002, Dec-06, Volume: 127, Issue:49

    Topics: Aphasia; Humans; Neuroprotective Agents; Nootropic Agents; Piracetam; Stroke

2002
Piracetam in the treatment of acute stroke.
    Pharmacopsychiatry, 1999, Volume: 32 Suppl 1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aphasia; Cerebrovascular Disorders; Female; Humans; M

1999