piracetam has been researched along with Allodynia in 8 studies
Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levetiracetam (200-1000 nmol/paw) produced a significant dose-dependent reduction of the paw inflammatory hyperalgesia and edema induced by carrageenan." | 7.78 | The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model. ( Micov, AM; Stepanović-Petrović, RM; Tomić, MA; Ugrešić, ND, 2012) |
| "Levetiracetam, a novel antiepileptic drug, has recently been shown to have antinociceptive effects in various animal models of pain." | 7.76 | The antihyperalgesic effect of levetiracetam in an inflammatory model of pain in rats: mechanism of action. ( Micov, A; Popović, B; Stepanović-Petrović, R; Tomić, M, 2010) |
| "Levetiracetam is an anticonvulsant which is assumed to act by modulating neurotransmitter release via binding to the vesicle protein SV2A." | 6.77 | A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis. ( Falah, M; Holbech, JV; Madsen, C; Sindrup, SH, 2012) |
| " These results suggest that ceftriaxone, particularly in combinations with ibuprofen, celecoxib, paracetamol, or levetiracetam, may provide useful approach to the clinical treatment of inflammation-related pain." | 3.80 | Antihyperalgesic/antinociceptive effects of ceftriaxone and its synergistic interactions with different analgesics in inflammatory pain in rodents. ( Boškovic, BD; Kovacevic, JM; Micov, AM; Stepanovic-Petrovic, RM; Tomic, MA, 2014) |
| " This study characterized the manner in which levetiracetam interacts with analgesics (ibuprofen, celecoxib, and paracetamol) and caffeine to suppress hyperalgesia in a model of localized inflammation." | 3.79 | Levetiracetam interacts synergistically with nonsteroidal analgesics and caffeine to produce antihyperalgesia in rats. ( Micov, AM; Stepanović-Petrović, RM; Tomić, MA, 2013) |
| "Levetiracetam (200-1000 nmol/paw) produced a significant dose-dependent reduction of the paw inflammatory hyperalgesia and edema induced by carrageenan." | 3.78 | The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model. ( Micov, AM; Stepanović-Petrović, RM; Tomić, MA; Ugrešić, ND, 2012) |
| "Levetiracetam, a novel antiepileptic drug, has recently been shown to have antinociceptive effects in various animal models of pain." | 3.76 | The antihyperalgesic effect of levetiracetam in an inflammatory model of pain in rats: mechanism of action. ( Micov, A; Popović, B; Stepanović-Petrović, R; Tomić, M, 2010) |
| " The pharmacological profile of the novel antiepileptic drug, levetiracetam, suggests that it may reduce the intensity of the excitatory stages of anesthesia." | 3.74 | Levetiracetam reduces anesthetic-induced hyperalgesia in rats. ( Archer, DP; Davis, MJ; Lamberty, Y; Roth, SH; Samanani, N; Wang, B, 2007) |
| "Levetiracetam is an anticonvulsant which is assumed to act by modulating neurotransmitter release via binding to the vesicle protein SV2A." | 2.77 | A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis. ( Falah, M; Holbech, JV; Madsen, C; Sindrup, SH, 2012) |
| "nefiracetam was also blocked by i." | 1.31 | Nonopioid and neuropathy-specific analgesic action of the nootropic drug nefiracetam in mice. ( Rashid, MH; Ueda, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomić, MA | 3 |
| Micov, AM | 3 |
| Stepanović-Petrović, RM | 3 |
| Kovacevic, JM | 1 |
| Boškovic, BD | 1 |
| Micov, A | 1 |
| Tomić, M | 1 |
| Popović, B | 1 |
| Stepanović-Petrović, R | 1 |
| Falah, M | 1 |
| Madsen, C | 1 |
| Holbech, JV | 1 |
| Sindrup, SH | 1 |
| Ugrešić, ND | 1 |
| Rashid, MH | 1 |
| Ueda, H | 1 |
| Ardid, D | 1 |
| Lamberty, Y | 2 |
| Alloui, A | 1 |
| Coudore-Civiale, MA | 1 |
| Klitgaard, H | 1 |
| Eschalier, A | 1 |
| Archer, DP | 1 |
| Wang, B | 1 |
| Davis, MJ | 1 |
| Samanani, N | 1 |
| Roth, SH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Placebo-Controlled Crossover Trial of Levetiracetam on Ethanol Intake[NCT01168687] | 46 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome of this study is to determine the effect of levetiracetam on alcohol consumption as measured by change in # of drinks during each treatment period. (NCT01168687)
Timeframe: During each 14 day treatment period
| Intervention | number of drinks per treatment period (Mean) |
|---|---|
| All Subjects (n = 46) Placebo | 41.2 |
| All Subjects (n = 46) Levetiracetam | 45.4 |
1 trial available for piracetam and Allodynia
| Article | Year |
|---|---|
A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis.
Topics: Adult; Analgesics; Anticonvulsants; Chronic Pain; Cross-Over Studies; Female; Humans; Hyperalgesia; | 2012 |
7 other studies available for piracetam and Allodynia
| Article | Year |
|---|---|
Levetiracetam interacts synergistically with nonsteroidal analgesics and caffeine to produce antihyperalgesia in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Celecoxib; Dr | 2013 |
Antihyperalgesic/antinociceptive effects of ceftriaxone and its synergistic interactions with different analgesics in inflammatory pain in rodents.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Ceftriaxone; Ce | 2014 |
The antihyperalgesic effect of levetiracetam in an inflammatory model of pain in rats: mechanism of action.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Hyperalgesia; | 2010 |
The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model.
Topics: Adenosine A1 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Carrag | 2012 |
Nonopioid and neuropathy-specific analgesic action of the nootropic drug nefiracetam in mice.
Topics: Analgesia; Animals; Diabetes Mellitus, Experimental; Hyperalgesia; Male; Mice; Mice, Inbred Strains; | 2002 |
Antihyperalgesic effect of levetiracetam in neuropathic pain models in rats.
Topics: Acute Disease; Analgesics; Animals; Carbamazepine; Chronic Disease; Constriction, Pathologic; Diabet | 2003 |
Levetiracetam reduces anesthetic-induced hyperalgesia in rats.
Topics: Anesthesia; Animals; Anticonvulsants; Hyperalgesia; Levetiracetam; Male; Models, Animal; Pain Thresh | 2007 |