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piracetam and Aggression

piracetam has been researched along with Aggression in 13 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"This study investigated to which degree levetiracetam (LEV) and perampanel (PER), antiseizure medications (ASM) that are both known to cause aggression and irritability, share the same or different, behavioral side-effect profiles."8.02Levetiracetam, perampanel, and the issue of aggression: A self-report study. ( Brand, F; Helmstaedter, C; Meschede, C; von Wrede, R, 2021)
"To investigate the efficacy and safety of levetiracetam adjunctive therapy in childhood intractable epilepsy, data were reviewed for 130 children who had >or=4 seizures per month, whose seizures were intractable to an initial >or=2 antiepileptic drugs, and who could be monitored for at least 6 months after levetiracetam add-on."7.76Efficacy and safety of adjunctive levetiracetam therapy in pediatric intractable epilepsy. ( Kang, HC; Kim, HD; Lee, JS; Lee, YJ, 2010)
"Levetiracetam (LEV) was shown to be very efficacious and well tolerated as add-on therapy for refractory epilepsy."7.72Aggressive behavior of epilepsy patients in the course of levetiracetam add-on therapy: report of 33 mild to severe cases. ( Dietl, T; Dinkelacker, V; Elger, CE; Lengler, U; Widman, G, 2003)
"Levetiracetam was not as efficacious as oxcarbazepine was in a prior similar study."6.73Levetiracetam in patients with impulsive aggression: a double-blind, placebo-controlled trial. ( Mattes, JA, 2008)
"The objectives of this study were to determine whether autistic children taking levetiracetam (1) showed improvement in the areas of aggression, impulsivity, hyperkinesis, and mood instability, and (2) showed a nootropic response."5.10Levetiracetam in autistic children: an open-label study. ( Rugino, TA; Samsock, TC, 2002)
"This study investigated to which degree levetiracetam (LEV) and perampanel (PER), antiseizure medications (ASM) that are both known to cause aggression and irritability, share the same or different, behavioral side-effect profiles."4.02Levetiracetam, perampanel, and the issue of aggression: A self-report study. ( Brand, F; Helmstaedter, C; Meschede, C; von Wrede, R, 2021)
"The purpose of this study was to identify clinical correlates of self-reported aggressiveness (SRA) in patients with epilepsy treated with levetiracetam (LEV) with special reference to the role of depression."3.81Self-reported aggressiveness during treatment with levetiracetam correlates with depression. ( Agrawal, N; Cock, HR; Lozsadi, DA; Mohanalingham, K; Mula, M; Mustafa, Z; von Oertzen, TJ, 2015)
"To investigate the efficacy and safety of levetiracetam adjunctive therapy in childhood intractable epilepsy, data were reviewed for 130 children who had >or=4 seizures per month, whose seizures were intractable to an initial >or=2 antiepileptic drugs, and who could be monitored for at least 6 months after levetiracetam add-on."3.76Efficacy and safety of adjunctive levetiracetam therapy in pediatric intractable epilepsy. ( Kang, HC; Kim, HD; Lee, JS; Lee, YJ, 2010)
"Levetiracetam (LEV) was shown to be very efficacious and well tolerated as add-on therapy for refractory epilepsy."3.72Aggressive behavior of epilepsy patients in the course of levetiracetam add-on therapy: report of 33 mild to severe cases. ( Dietl, T; Dinkelacker, V; Elger, CE; Lengler, U; Widman, G, 2003)
"Levetiracetam-treated patients manifested an early augmentation of self-rated aggressiveness, which increased in intensity over the course of days."2.73Early detection of behavioral side effects of antiepileptic treatment using handheld computers. ( Carius, A; Frings, L; Lehmann, C; Maiwald, T; Schinkel, A; Schulze-Bonhage, A; Wagner, K, 2008)
"Levetiracetam was not as efficacious as oxcarbazepine was in a prior similar study."2.73Levetiracetam in patients with impulsive aggression: a double-blind, placebo-controlled trial. ( Mattes, JA, 2008)
"Levetiracetam (LEV) is a highly effective antiepileptic agent."2.49Genetic variation in dopaminergic activity is associated with the risk for psychiatric side effects of levetiracetam. ( Elger, CE; Helmstaedter, C; Hurlemann, R; Kunz, WS; Mihov, Y; Nuernberg, P; Schoch, S; Surges, R; Thiele, H; Toliat, MR, 2013)
"Piracetam in both doses was less effective in avoidance learning of aggressive rats."1.27Behavioral effects of piracetam in rats with isolation syndrome. ( Dimov, S; Petkov, VV; Rousseva, S, 1984)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's1 (7.69)18.2507
2000's5 (38.46)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
von Wrede, R1
Meschede, C1
Brand, F1
Helmstaedter, C2
Chung, S1
Williams, B1
Dobrinsky, C1
Patten, A1
Yang, H1
Laurenza, A1
Mula, M1
Agrawal, N1
Mustafa, Z1
Mohanalingham, K1
Cock, HR1
Lozsadi, DA1
von Oertzen, TJ1
Frings, L1
Wagner, K1
Maiwald, T1
Carius, A1
Schinkel, A1
Lehmann, C1
Schulze-Bonhage, A1
Belcastro, V1
Costa, C1
Galletti, F1
Autuori, A1
Pierguidi, L1
Pisani, F1
Calabresi, P1
Parnetti, L1
Lee, YJ1
Kang, HC1
Kim, HD1
Lee, JS1
Mihov, Y1
Toliat, MR1
Thiele, H1
Nuernberg, P1
Schoch, S1
Surges, R1
Elger, CE2
Kunz, WS1
Hurlemann, R1
Rugino, TA1
Samsock, TC1
Dinkelacker, V1
Dietl, T1
Widman, G1
Lengler, U1
Mattes, JA1
Gualtieri, CT1
Golden, RN1
Fahs, JJ1
Petkov, VV1
Rousseva, S1
Dimov, S1
Pant, KK1
Nath, C1

Reviews

3 reviews available for piracetam and Aggression

ArticleYear
Perampanel with concomitant levetiracetam and topiramate: Post hoc analysis of adverse events related to hostility and aggression.
    Epilepsy & behavior : E&B, 2017, Volume: 75

    Topics: Adolescent; Adult; Aged; Aggression; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies,

2017
Genetic variation in dopaminergic activity is associated with the risk for psychiatric side effects of levetiracetam.
    Epilepsia, 2013, Volume: 54, Issue:1

    Topics: Adult; Aggression; Anticonvulsants; Catechol O-Methyltransferase; Dopamine; Dopamine beta-Hydroxylas

2013
New developments in pediatric psychopharmacology.
    Journal of developmental and behavioral pediatrics : JDBP, 1983, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder

1983

Trials

5 trials available for piracetam and Aggression

ArticleYear
Early detection of behavioral side effects of antiepileptic treatment using handheld computers.
    Epilepsy & behavior : E&B, 2008, Volume: 13, Issue:2

    Topics: Adult; Aggression; Ambulatory Care; Anticonvulsants; Attention; Attitude to Computers; Cognition; Co

2008
Levetiracetam in newly diagnosed late-onset post-stroke seizures: a prospective observational study.
    Epilepsy research, 2008, Volume: 82, Issue:2-3

    Topics: Aged; Aged, 80 and over; Aggression; Anticonvulsants; Brain Ischemia; Cardiovascular Agents; Drug In

2008
Levetiracetam in autistic children: an open-label study.
    Journal of developmental and behavioral pediatrics : JDBP, 2002, Volume: 23, Issue:4

    Topics: Aggression; Anticonvulsants; Autistic Disorder; Cetirizine; Child; Child Behavior Disorders; Child,

2002
Levetiracetam in patients with impulsive aggression: a double-blind, placebo-controlled trial.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:2

    Topics: Adult; Aggression; Disruptive, Impulse Control, and Conduct Disorders; Double-Blind Method; Female;

2008
New developments in pediatric psychopharmacology.
    Journal of developmental and behavioral pediatrics : JDBP, 1983, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder

1983

Other Studies

6 other studies available for piracetam and Aggression

ArticleYear
Levetiracetam, perampanel, and the issue of aggression: A self-report study.
    Epilepsy & behavior : E&B, 2021, Volume: 117

    Topics: Aggression; Anticonvulsants; Humans; Levetiracetam; Nitriles; Piracetam; Pyridones; Self Report

2021
Self-reported aggressiveness during treatment with levetiracetam correlates with depression.
    Epilepsy & behavior : E&B, 2015, Volume: 45

    Topics: Adult; Aggression; Anticonvulsants; Depressive Disorder, Major; Epilepsy; Female; Humans; Levetirace

2015
Efficacy and safety of adjunctive levetiracetam therapy in pediatric intractable epilepsy.
    Pediatric neurology, 2010, Volume: 42, Issue:2

    Topics: Adolescent; Age Factors; Aggression; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Irri

2010
Aggressive behavior of epilepsy patients in the course of levetiracetam add-on therapy: report of 33 mild to severe cases.
    Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:5

    Topics: Adult; Aged; Aggression; Anticonvulsants; Drug Resistance; Drug Therapy, Combination; Epilepsy; Fema

2003
Behavioral effects of piracetam in rats with isolation syndrome.
    Acta physiologica et pharmacologica Bulgarica, 1984, Volume: 10, Issue:3

    Topics: Aggression; Animals; Avoidance Learning; Brain Chemistry; gamma-Aminobutyric Acid; Humans; Male; Pir

1984
Dopaminergic involvement in the effects of piracetam on foot shock induced aggression in mice.
    The Indian journal of medical research, 1993, Volume: 98

    Topics: Aggression; Animals; Dopamine Agents; Female; Male; Mice; Piracetam; Stress, Physiological

1993