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piracetam and Adolescent Myoclonic Epilepsy

piracetam has been researched along with Adolescent Myoclonic Epilepsy in 22 studies

Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.

Research Excerpts

ExcerptRelevanceReference
"Levetiracetam was well tolerated and effective as add-on treatment in partial and generalised seizures."5.32[Levetiracetam in the treatment of epilepsy]. ( Brodtkorb, E; Johannessen, SI; Lossius, R; Mariero Klees, T; Nakken, KO, 2003)
"Lennox-Gastaut syndrome is an epileptic encephalopathy characterized by multiple seizure types, mental retardation, and a slow spike-and-wave pattern on electroencephalography."5.32Levetiracetam in the treatment of Lennox-Gastaut syndrome. ( De Los Reyes, EC; Hale, SE; Sharp, GB; Williams, JP, 2004)
" Oral treatment with levetiracetam resolved his seizures."3.80Generalised electrographic seizures presenting as perioral myoclonia. ( Dearborn, JL; Kaplan, PW, 2014)
"Patients with juvenile myoclonic epilepsy (JME) may be resistant or show adverse effects to valproate."2.72Open label, long-term, pragmatic study on levetiracetam in the treatment of juvenile myoclonic epilepsy. ( Boero, G; Gambardella, A; Giallonardo, AT; La Neve, A; Michelucci, R; Specchio, LM; Specchio, N, 2006)
"Levetiracetam was well tolerated; no patient reported side-effects."2.71Clinical experience with levetiracetam in idiopathic generalized epilepsy according to different syndrome subtypes. ( Di Bonaventura, C; Egeo, G; Fattouch, J; Giallonardo, AT; Manfredi, M; Mari, F; Prencipe, M; Vaudano, AE, 2005)
"Myoclonic jerks are frequently the debut symptom, while tonic-clonic seizures appear later on."2.48[Juvenile myoclonic epilepsy]. ( Markhus, R; Nakken, KO; Selmer, KK; Syvertsen, MR, 2012)
"Juvenile myoclonic epilepsy is a common idiopathic generalized epileptic syndrome that includes generalized myoclonic seizures and commonly generalized tonic-clonic and generalized absence seizures."2.45The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent? ( Abou-Khalil, B; Montouris, G, 2009)
"Drug treatment of juvenile myoclonic epilepsy (JME) is mainly based on clinical experience and prospective and retrospective studies, with little evidence from randomized clinical trials."2.44Treatment of juvenile myoclonic epilepsy. ( Auvin, S, 2008)
"West syndrome is an age-dependent epilepsy with onset peak in the first year of life whose aetiology may be symptomatic or cryptogenic."1.39West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence? ( Fontana, A; Giordano, G; Mangano, GR; Mangano, S; Nardello, R; Spitaleri, C; Tripi, G, 2013)
"When lamotrigine was restarted 2 weeks later she developed similar but more severe symptoms which resolved on stopping lamotrigine."1.35Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis. ( Bazaz, R; Lily, O; Maniyar, F; Rooney, C, 2009)
"We have treated a patient with juvenile myoclonic epilepsy who had frequent and inconvenient morning myoclonus with 3,200 mg of piracetam daily."1.33Antimyoclonic efficacy of piracetam in idiopathic generalized epilepsy. ( Andermann, E; Andermann, F; Khani, YA, 2005)
"Levetiracetam was well tolerated and effective as add-on treatment in partial and generalised seizures."1.32[Levetiracetam in the treatment of epilepsy]. ( Brodtkorb, E; Johannessen, SI; Lossius, R; Mariero Klees, T; Nakken, KO, 2003)
"Lennox-Gastaut syndrome is an epileptic encephalopathy characterized by multiple seizure types, mental retardation, and a slow spike-and-wave pattern on electroencephalography."1.32Levetiracetam in the treatment of Lennox-Gastaut syndrome. ( De Los Reyes, EC; Hale, SE; Sharp, GB; Williams, JP, 2004)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's16 (72.73)29.6817
2010's6 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mangano, S1
Nardello, R1
Tripi, G1
Giordano, G1
Spitaleri, C1
Mangano, GR1
Fontana, A1
Dearborn, JL1
Kaplan, PW1
Chowdhury, A1
Brodie, MJ1
Auvin, S1
Belcastro, V1
Costa, C1
Galletti, F1
Rossi, A1
Tambasco, N1
Striano, P1
Rosenfeld, WE1
Benbadis, S1
Edrich, P1
Tassinari, CA1
Hirsch, E1
Maniyar, F1
Rooney, C1
Lily, O1
Bazaz, R1
Montouris, G1
Abou-Khalil, B2
Khan, S1
Syvertsen, MR1
Markhus, R1
Selmer, KK1
Nakken, KO3
Karlov, VA1
Freĭdkova, NV1
Rusanova, LV1
Mariero Klees, T1
Brodtkorb, E2
Lossius, R2
Johannessen, SI2
De Los Reyes, EC1
Sharp, GB1
Williams, JP1
Hale, SE1
Klees, TM1
Khani, YA1
Andermann, F1
Andermann, E1
Di Bonaventura, C2
Fattouch, J2
Mari, F1
Egeo, G1
Vaudano, AE1
Prencipe, M1
Manfredi, M1
Giallonardo, AT3
Specchio, LM2
Gambardella, A2
Michelucci, R2
Specchio, N2
Boero, G2
La Neve, A2
Plattner, B1
Pahs, G1
Kindler, J1
Williams, RP1
Hall, RE1
Mayer, H1
Steiner, H1
Feucht, M1
Sharpe, DV1
Patel, AD1
Fenichel, GM1
Verrotti, A1
Cerminara, C1
Coppola, G1
Franzoni, E1
Parisi, P1
Iannetti, P1
Aloisi, P1
Tozzi, E1
Cusmai, R1
Vigevano, F2
Chiarelli, F1
Curatolo, P1
de Palo, A1
Ladogana, M1
Lamberti, P1
Schauer, R1
Singer, M1
Saltuari, L1
Kofler, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind, Multicenter, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of Levetiracetam (LEV) (Oral Tablets of 500 mg b.i.d.) at a Dose of 3000 mg/Day as Adjunctive Treatment in Adolescents (≥ 12 Years) and Adults (≤ 65 Year[NCT00150774]Phase 3116 participants Interventional2001-11-30Completed
A Double-blind, Multicenter, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adjunctive Treatment With 3000 mg/Day (Pediatric Target Dose of 60 mg/kg/Day) Oral Levetiracetam (LEV) (166, 250, and 500mg Tablets), in Adult and Ped[NCT00160550]Phase 3154 participants Interventional2001-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for piracetam and Adolescent Myoclonic Epilepsy

ArticleYear
Treatment of juvenile myoclonic epilepsy.
    CNS neuroscience & therapeutics, 2008,Fall, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Lamotrigine; Le

2008
The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?
    Epilepsia, 2009, Volume: 50 Suppl 8

    Topics: Anticonvulsants; Congenital Abnormalities; Delayed-Action Preparations; Drug Design; Epilepsy, Gener

2009
[Juvenile myoclonic epilepsy].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2012, Aug-07, Volume: 132, Issue:14

    Topics: Adolescent; Anticonvulsants; Diagnosis, Differential; Electroencephalography; Female; Humans; Lamotr

2012

Trials

5 trials available for piracetam and Adolescent Myoclonic Epilepsy

ArticleYear
Levetiracetam as add-on therapy for idiopathic generalized epilepsy syndromes with onset during adolescence: analysis of two randomized, double-blind, placebo-controlled studies.
    Epilepsy research, 2009, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blin

2009
Levetiracetam as add-on therapy for idiopathic generalized epilepsy syndromes with onset during adolescence: analysis of two randomized, double-blind, placebo-controlled studies.
    Epilepsy research, 2009, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blin

2009
Levetiracetam as add-on therapy for idiopathic generalized epilepsy syndromes with onset during adolescence: analysis of two randomized, double-blind, placebo-controlled studies.
    Epilepsy research, 2009, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blin

2009
Levetiracetam as add-on therapy for idiopathic generalized epilepsy syndromes with onset during adolescence: analysis of two randomized, double-blind, placebo-controlled studies.
    Epilepsy research, 2009, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blin

2009
Clinical experience with levetiracetam in idiopathic generalized epilepsy according to different syndrome subtypes.
    Epileptic disorders : international epilepsy journal with videotape, 2005, Volume: 7, Issue:3

    Topics: Anticonvulsants; Electroencephalography; Epilepsy, Absence; Female; Humans; Levetiracetam; Male; Myo

2005
Open label, long-term, pragmatic study on levetiracetam in the treatment of juvenile myoclonic epilepsy.
    Epilepsy research, 2006, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Female

2006
Levetiracetam in juvenile myoclonic epilepsy: long-term efficacy in newly diagnosed adolescents.
    Developmental medicine and child neurology, 2008, Volume: 50, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Female; Follow-Up Studies; Humans; Levetiracetam; Male; Myocloni

2008
Effects of levetiracetam on EEG abnormalities in juvenile myoclonic epilepsy.
    Epilepsia, 2008, Volume: 49, Issue:4

    Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Dose-Response Relationship, Drug; Drug Resistance;

2008

Other Studies

14 other studies available for piracetam and Adolescent Myoclonic Epilepsy

ArticleYear
West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence?
    BMC neurology, 2013, May-24, Volume: 13

    Topics: Adolescent; Brain; Disease Progression; Humans; Infant; Levetiracetam; Magnetic Resonance Imaging; M

2013
Generalised electrographic seizures presenting as perioral myoclonia.
    Epileptic disorders : international epilepsy journal with videotape, 2014, Volume: 16, Issue:1

    Topics: Adult; Diagnosis, Differential; Electroencephalography; Humans; Levetiracetam; Male; Myoclonic Epile

2014
Pharmacological outcomes in juvenile myoclonic epilepsy: Support for sodium valproate.
    Epilepsy research, 2016, Volume: 119

    Topics: Adolescent; Adult; Anticonvulsants; Child; Comorbidity; Drug Resistant Epilepsy; Female; Follow-Up S

2016
Rapid effect of levetiracetam in a case of juvenile myoclonic epilepsy.
    Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:1

    Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Levetiraceta

2009
Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis.
    Journal of neurology, 2009, Volume: 256, Issue:7

    Topics: Anti-Bacterial Agents; Anticonvulsants; Drug Administration Schedule; Drug-Related Side Effects and

2009
Juvenile myoclonic epilepsy.
    Neurosciences (Riyadh, Saudi Arabia), 2010, Volume: 15, Issue:3

    Topics: Anticonvulsants; Electroencephalography; Family Health; Humans; Levetiracetam; Mutation; Myoclonic E

2010
[Complex therapy of idiopathic forms of epilepsy with small doses of valproates and levetiracetam].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:6 Pt 2

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Absence;

2012
[Levetiracetam in the treatment of epilepsy].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, May-29, Volume: 123, Issue:11

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Drug Interactions; Epilepsy; Female; Follow-Up Studies; Hu

2003
Levetiracetam in the treatment of Lennox-Gastaut syndrome.
    Pediatric neurology, 2004, Volume: 30, Issue:4

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Generaliz

2004
Levetiracetam in adult patients with and without learning disability: focus on behavioral adverse effects.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Dose-Response Relationship, Drug; Drug Resistance; Drug Th

2004
Antimyoclonic efficacy of piracetam in idiopathic generalized epilepsy.
    Epilepsia, 2005, Volume: 46, Issue:7

    Topics: Comorbidity; Epilepsy, Generalized; Female; Follow-Up Studies; Humans; Middle Aged; Myoclonic Epilep

2005
Juvenile myoclonic epilepsy: a benign disorder? Personality traits and psychiatric symptoms.
    Epilepsy & behavior : E&B, 2007, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Child; Ethosuximide; Female; Fructose; Humans; Lamotrigine; Leve

2007
Levetiracetam monotherapy in juvenile myoclonic epilepsy.
    Seizure, 2008, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Child; Data Interpretation, Statistical; Electroencephalography;

2008
Suppression of cortical myoclonus by levetiracetam.
    Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:2

    Topics: Adolescent; Anticonvulsants; Cerebral Cortex; Dominance, Cerebral; Drug Therapy, Combination; Epilep

2002