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pipobroman and Leukemia, Radiation-Induced

pipobroman has been researched along with Leukemia, Radiation-Induced in 4 studies

Pipobroman: An antineoplastic agent that acts by alkylation.
pipobroman : An N-acylpiperazine that is piperazine in which each of the nitrogens has been acylated by a 3-bromopropionoyl group. An anti-cancer drug.

Leukemia, Radiation-Induced: Leukemia produced by exposure to IONIZING RADIATION or NON-IONIZING RADIATION.

Research Excerpts

ExcerptRelevanceReference
"An analysis of the risk of progression towards leukemia, carcinoma and myelofibrosis was performed in 93 patients treated by 32P alone (PVSG protocols) since 1970-1979, 395 patients over the age of 65 years treated by 32P with or without maintenance therapy using hydroxyurea (French protocol) since 1980-1994, and 202 patients under the age of 65 treated by either hydroxyurea or pipobroman since 1980."6.18Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias". ( Dresch, C; Echard, M; Goguel, A; Grange, MJ; Lejeune, F; Najean, Y; Rain, JD, 1996)
" Randomized studies have shown that the risk of thrombosis was significantly reduced in ET with the use of hydroxyurea (HU) and in PV with the use of chlorambucil or 32P."4.80Treatment of polycythaemia vera and essential thrombocythaemia. ( Silverstein, MN; Tefferi, A, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Najean, Y1
Rain, JD1
Dresch, C1
Goguel, A1
Lejeune, F1
Echard, M1
Grange, MJ1
Sánchez Fayos, J1
Román Barbero, A1
Nevado Reviriego, I1
Tefferi, A1
Silverstein, MN1
Vallée, G1
Boivin, P1
Dormont, J1
Soulier, JP1

Reviews

3 reviews available for pipobroman and Leukemia, Radiation-Induced

ArticleYear
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996
[Efficacious treatment of a fatal blood disease: polycythemia vera].
    Sangre, 1997, Volume: 42, Issue:3

    Topics: Acute Disease; Alkylating Agents; Busulfan; Chlorambucil; Humans; Hydroxyurea; Leukemia, Myeloid; Le

1997
Treatment of polycythaemia vera and essential thrombocythaemia.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; In

1998

Trials

1 trial available for pipobroman and Leukemia, Radiation-Induced

ArticleYear
Risk of leukaemia, carcinoma, and myelofibrosis in 32P- or chemotherapy-treated patients with polycythaemia vera: a prospective analysis of 682 cases. The "French Cooperative Group for the Study of Polycythaemias".
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Actuarial Analysis; Acute Disease; Carcinoma; Cause of Death; Disease Progression; Follow-Up Studies

1996

Other Studies

1 other study available for pipobroman and Leukemia, Radiation-Induced

ArticleYear
[Present treatment of the Vaquez's disease].
    La Presse medicale, 1969, Mar-22, Volume: 77, Issue:14

    Topics: Aged; Anemia; Anticoagulants; Antineoplastic Agents; Blood Donors; Blood Volume; Bloodletting; Busul

1969