pipobroman has been researched along with Leukemia, Myeloid, Acute in 6 studies
Pipobroman: An antineoplastic agent that acts by alkylation.
pipobroman : An N-acylpiperazine that is piperazine in which each of the nitrogens has been acylated by a 3-bromopropionoyl group. An anti-cancer drug.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A trial was conducted between 1970 and 1981 with pipobroman (PB) in 100 consecutive patients with polycythemia vera (PV), followed for a median time of 60 months, to evaluate the efficacy of this drug and assess the risk of acute leukemia." | 9.05 | Efficacy trial of pipobroman in polycythemia vera and incidence of acute leukemia. ( Bernasconi, C; Brusamolino, E; Canevari, A; Salvaneschi, L, 1984) |
| "A trial was conducted between 1970 and 1981 with pipobroman (PB) in 100 consecutive patients with polycythemia vera (PV), followed for a median time of 60 months, to evaluate the efficacy of this drug and assess the risk of acute leukemia." | 5.05 | Efficacy trial of pipobroman in polycythemia vera and incidence of acute leukemia. ( Bernasconi, C; Brusamolino, E; Canevari, A; Salvaneschi, L, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abruzzese, E | 1 |
| Trawinska, MM | 1 |
| Neri, B | 1 |
| Bondanini, F | 1 |
| Fratoni, S | 1 |
| Tendas, A | 1 |
| Scaramucci, L | 1 |
| Siniscalchi, A | 1 |
| Giovannini, M | 1 |
| Palumbo, R | 1 |
| de Fabritiis, P | 1 |
| Niscola, P | 1 |
| Stein, BL | 1 |
| Moliterno, AR | 1 |
| Tiu, RV | 1 |
| Herry, A | 1 |
| Douet-Guilbert, N | 1 |
| Guéganic, N | 1 |
| Morel, F | 1 |
| Le Bris, MJ | 1 |
| Berthou, C | 1 |
| De Braekeleer, M | 1 |
| Brusamolino, E | 1 |
| Salvaneschi, L | 1 |
| Canevari, A | 1 |
| Bernasconi, C | 1 |
| Randi, ML | 1 |
| Fabris, F | 1 |
| Girolami, A | 1 |
1 review available for pipobroman and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Polycythemia vera disease burden: contributing factors, impact on quality of life, and emerging treatment options.
Topics: Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cost of Illness; Disease Progression | 2014 |
1 trial available for pipobroman and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Efficacy trial of pipobroman in polycythemia vera and incidence of acute leukemia.
Topics: Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Leukemia, Monocytic, Acute; Leukemia, M | 1984 |
4 other studies available for pipobroman and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Successful Decitabine Treatment in Unfit, Elderly Patients with Acute Myeloid Leukemia following Chronic Myeloproliferative Neoplasm.
Topics: Aged; Decitabine; Female; Humans; Hydroxyurea; Janus Kinase 2; Leukemia, Myeloid, Acute; Male; Myelo | 2018 |
Del(5q) and MLL amplification in homogeneously staining region in acute myeloblastic leukemia: a recurrent cytogenetic association.
Topics: Aged; Chromosome Deletion; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 5; Chromosomes, Hum | 2006 |
Leukemia and myelodysplasia in patients with essential thrombocythemia treated with cytotoxic agents.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Busulfan; Female; Follow-Up Studies; Humans; | 1999 |
Drugs in the treatment of leukemia.
Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; L | 1968 |