piperonyl butoxide has been researched along with Necrosis in 14 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although the exact sequence of its hepatotoxic factors is unproven, it seems likely that lipid peroxidation through the dysfunction of antioxidant defence factors and a toxic metabolite contribute to the formation of this liver injury." | 1.28 | Hepatotoxicity of diethyldithiocarbamate in rats. ( Hobara, T; Ishiyama, H; Kanbe, T; Ogino, K; Shimomura, Y, 1990) |
| "Hepatic necrosis was relatively mild, and was not observed in all animals treated with 1,1-DCE." | 1.27 | Effects of administration of metabolic inducers and inhibitors on pulmonary toxicity and covalent binding by 1,1-dichloroethylene in CD-1 mice. ( Forkert, PG; Racz, WJ; Stringer, V, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Warren, DL | 1 |
| Brown, DL | 1 |
| Buckpitt, AR | 1 |
| Okamiya, H | 1 |
| Mitsumori, K | 1 |
| Onodera, H | 1 |
| Ito, S | 1 |
| Imazawa, T | 1 |
| Yasuhara, K | 1 |
| Takahashi, M | 1 |
| Ishiyama, H | 1 |
| Ogino, K | 1 |
| Shimomura, Y | 1 |
| Kanbe, T | 1 |
| Hobara, T | 1 |
| Forkert, PG | 1 |
| Stringer, V | 1 |
| Racz, WJ | 1 |
| Potter, WZ | 5 |
| Davis, DC | 3 |
| Mitchell, JR | 6 |
| Jollow, DJ | 5 |
| Gillette, JR | 3 |
| Brodie, BB | 4 |
| Thorgeirsson, SS | 2 |
| Hashimoto, M | 1 |
| Reid, WD | 5 |
| Krishna, G | 4 |
| Ilett, KF | 2 |
| Glick, JM | 1 |
| Sipes, IG | 1 |
| Christie, B | 1 |
| Moskowitz, J | 1 |
14 other studies available for piperonyl butoxide and Necrosis
| Article | Year |
|---|---|
Evidence for cytochrome P-450 mediated metabolism in the bronchiolar damage by naphthalene.
Topics: Animals; Bronchi; Cytochrome P-450 Enzyme System; Glutathione; Lung; Male; Maleates; Mice; Mice, Inb | 1982 |
Mechanistic study on liver tumor promoting effects of piperonyl butoxide in rats.
Topics: Animals; Body Weight; Carcinogens; Cell Division; Connexins; Cytochrome P-450 CYP2B1; Eating; Gap Ju | 1998 |
Hepatotoxicity of diethyldithiocarbamate in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Deferoxamine; Ditiocarb; Gluta | 1990 |
Effects of administration of metabolic inducers and inhibitors on pulmonary toxicity and covalent binding by 1,1-dichloroethylene in CD-1 mice.
Topics: Animals; Bronchi; Dichloroethylenes; Drug Interactions; Hydrocarbons, Chlorinated; Lung; Male; Methy | 1986 |
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced L | 1973 |
Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cricetinae; Depression, Chemical; Gl | 1974 |
Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Animals; Cricetinae; Depression, Chemical; Glutathione; Liver; Mass S | 1974 |
Centrolobular hepatic necrosis related to covalent binding of metabolites of halogenated aromatic hydrocarbons.
Topics: Animals; Benzene Derivatives; Bromine; Chemical and Drug Induced Liver Injury; Enzyme Induction; Glu | 1973 |
Metabolism and binding of aromatic hydrocarbons in the lung. Relationship to experimental bronchiolar necrosis.
Topics: Animals; Autoradiography; Bromine; Bronchial Diseases; Carbon Isotopes; Chemical and Drug Induced Li | 1973 |
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cobalt; Dose-Response Relationship, | 1973 |
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo.
Topics: Acetaminophen; Animals; Carbon Radioisotopes; Cell Nucleus; Chemical and Drug Induced Liver Injury; | 1973 |
Mechanism of renal necrosis induced by bromobenzene or chlorobenzene.
Topics: Animals; Benzene Derivatives; Carbon Radioisotopes; Chlorobenzenes; Cytochrome P-450 Enzyme System; | 1973 |
Chloroform toxicity in mice: correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Chloroform; Cytochrome P-450 Enzyme System; Female; Hi | 1973 |
Bromobenzene metabolism and hepatic necrosis.
Topics: Adipose Tissue; Animals; Benzene Derivatives; Bromine; Carbon Isotopes; Chemical and Drug Induced Li | 1971 |