Page last updated: 2024-11-06

piperonyl butoxide and Malaria

piperonyl butoxide has been researched along with Malaria in 46 studies

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
" culicifacies have shown that chlorfenapyr can be a suitable insecticide for malaria vector control, in multiple-insecticide-resistant mosquitoes especially in areas with pyrethroid resistant mosquitoes."7.77Chlorfenapyr: a new insecticide with novel mode of action can control pyrethroid resistant malaria vectors. ( Barik, TK; Bhatt, RM; Dash, AP; Raghavendra, K; Sharma, P; Sreehari, U; Srivastava, HC, 2011)
"Piperonyl butoxide (PBO) is a synergist that inhibits specific metabolic enzymes within mosquitoes and has been incorporated into pyrethroid-LLINs to form pyrethroid-PBO nets."6.58Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa. ( Choi, L; Gleave, K; Lissenden, N; Ranson, H; Richardson, M, 2018)
"Chlorfenapyr pyrethroid LLINs were the most effective intervention against the main malaria vector An funestus sl over 3 years of community use, whereas the effect of piperonyl-butoxide pyrethroid LLIN was sustained for 2 years."5.69Differential impact of dual-active ingredient long-lasting insecticidal nets on primary malaria vectors: a secondary analysis of a 3-year, single-blind, cluster-randomised controlled trial in rural Tanzania. ( Jumanne, M; Kaaya, R; Kulkarni, MA; Lukole, E; Mallya, E; Manjurano, A; Martin, J; Matowo, NS; Messenger, LA; Mosha, FW; Mosha, JF; Moshi, O; Protopopoff, N; Rowland, M; Shirima, B, 2023)
"Our phenotypic data supports trial epidemiological findings; chlorfenapyr PY-LLINs provided superior protection from malaria across multiple transmission seasons, with few effects on insecticide-resistance selection."5.69Effects of next-generation, dual-active-ingredient, long-lasting insecticidal net deployment on insecticide resistance in malaria vectors in Tanzania: an analysis of a 3-year, cluster-randomised controlled trial. ( Cross, CL; Fullerton, K; Jumanne, M; Kaaya, R; Kulkarni, MA; Lukole, E; Mallya, E; Manjurano, A; Martin, J; Matowo, NS; Messenger, LA; Mosha, FW; Mosha, JF; Moshi, O; Pelloquin, B; Portwood, NM; Protopopoff, N; Rowland, M; Walker, T, 2023)
"In view of widespread pyrethroid resistance in malaria vectors in Africa, two long-lasting insecticidal nets (LLINs) incorporated with a synergist, piperonyl butoxide (PBO), DawaPlus 3."3.91Experimental hut evaluation of DawaPlus 3.0 LN and DawaPlus 4.0 LN treated with deltamethrin and PBO against free-flying populations of Anopheles gambiae s.l. in Vallée du Kou, Burkina Faso. ( Bayili, K; Dabiré, RK; Diabaté, A; N'Do, S; Namountougou, M; Ouattara, A; Ouédraogo, GA; Yadav, RS, 2019)
"LLINs containing an insecticide plus the synergist, piperonyl butoxide (PBO) have been designed for increased efficacy against pyrethroid-resistant malaria vectors."3.88Efficacy of two PBO long lasting insecticidal nets against natural populations of Anopheles gambiae s.l. in experimental huts, Kolokopé, Togo. ( Ahadji-Dabla, KM; Amoudji, AD; Apetogbo, GY; Awokou, F; Chabi, J; Glitho, IA; Ketoh, GK, 2018)
" culicifacies have shown that chlorfenapyr can be a suitable insecticide for malaria vector control, in multiple-insecticide-resistant mosquitoes especially in areas with pyrethroid resistant mosquitoes."3.77Chlorfenapyr: a new insecticide with novel mode of action can control pyrethroid resistant malaria vectors. ( Barik, TK; Bhatt, RM; Dash, AP; Raghavendra, K; Sharma, P; Sreehari, U; Srivastava, HC, 2011)
"Piperonyl butoxide (PBO) is a synergist that inhibits the activity of metabolic enzymes of the cytochrome P450 family known to detoxify insecticides including pyrethroids."2.90Evaluation of an alpha-cypermethrin + PBO mixture long-lasting insecticidal net VEERALIN® LN against pyrethroid resistant Anopheles gambiae s.s.: an experimental hut trial in M'bé, central Côte d'Ivoire. ( Alou, LPA; Camara, S; Koffi, AA; N'Guessan, R; Oumbouke, WA; Rowland, M, 2019)
"Piperonyl butoxide (PBO) is a synergist that inhibits specific metabolic enzymes within mosquitoes and has been incorporated into pyrethroid-LLINs to form pyrethroid-PBO nets."2.58Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa. ( Choi, L; Gleave, K; Lissenden, N; Ranson, H; Richardson, M, 2018)
"The Piperonyl Butoxide (PBO) was used to enhance the activity of these oils with the aim of developing essential oil based formulations."1.35Effect of synergist piperonyl butoxide (PBO) on the toxicity of some essential oils against mosquito larvae. ( Mittal, PK; Saxena, PN; Singh, RK; Yadav, S, 2008)
"The Piperonyl Butoxide (PBO) was used to enhance the activity of these oils with the aim of developing essential oil based formulations."1.35Effect of synergist piperonyl butoxide (PBO) on the toxicity of some essential oils against mosquito larvae. ( Mittal, PK; Saxena, PN; Singh, RK; Yadav, S, 2009)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (6.52)29.6817
2010's17 (36.96)24.3611
2020's26 (56.52)2.80

Authors

AuthorsStudies
Zhou, G1
Lee, MC1
Wang, X1
Zhong, D1
Hemming-Schroeder, E1
Yan, G1
Roh, ME1
Oundo, B1
Dorsey, G6
Shiboski, S1
Gosling, R1
Glymour, MM1
Staedke, SG7
Bennett, A1
Sturrock, H1
Mpimbaza, A1
Ngufor, C3
Fagbohoun, J1
Agbevo, A2
Ismail, H1
Challenger, JD1
Churcher, TS3
Rowland, M9
Sherrard-Smith, E1
Winskill, P1
Hamlet, A1
N'Guessan, R3
Guelbeogo, MW1
Sanou, A1
Nash, RK1
Hill, A1
Russell, EL1
Woodbridge, M1
Tungu, P1
Kont, MD1
Mclean, T1
Fornadel, C2
Richardson, JH1
Donnelly, MJ6
Gonahasa, S5
Protopopoff, N6
Syme, T1
Gbegbo, M1
Obuobi, D1
Fongnikin, A1
Todjinou, D1
Ngonghala, CN1
Maiteki-Sebuguzi, C4
Kamya, MR5
Katureebe, A3
Bagala, I1
Lynd, A4
Mutungi, P2
Kigozi, SP2
Opigo, J4
Hemingway, J4
Mangani, C2
Mzilahowa, T2
Cohee, L1
Kayange, M1
Ntenda, P2
Sixpence, A2
Gumbo, A1
Lankhulani, S1
Goupeyou-Youmsi, J2
Walker, E1
Laufer, M1
Valim, C2
Seydel, K1
Wilson, ML2
Taylor, T1
Mathanga, DP2
Cohee, LM1
Seydel, KB1
Mbewe, RB1
Matengeni, A1
Takala-Harrison, S1
Walker, ED1
Laufer, MK1
Taylor, TE1
Nankabirwa, JI1
Rek, J1
Arinaitwe, E1
Namuganga, JF1
Nsobya, SL1
Asua, V1
Mawejje, HD1
Epstein, A1
Greenhouse, B1
Rodriguez-Barraquer, I1
Briggs, J1
Krezanoski, PJ1
Rosenthal, PJ1
Conrad, M1
Smith, D1
Drakeley, C1
Bousema, T1
Andolina, C1
Azizi, S1
Matowo, J1
Mbewe, NJ1
Athumani, R1
Matiku, W1
Shayo, M1
Tenu, F1
Mosha, F1
Kitau, J1
Mbuba, E1
Odufuwa, OG1
Moore, J1
Mmbaga, S1
Tchicaya, E1
Edi, C2
Chalageri, V1
Uragayala, S1
Sharma, A1
Rahi, M1
Raghavendra, K2
Eapen, A1
Koenker, H1
Ross, A1
Moore, SJ1
Matowo, NS2
Kulkarni, MA2
Messenger, LA4
Jumanne, M2
Martin, J2
Mallya, E2
Lukole, E4
Mosha, JF4
Moshi, O2
Shirima, B1
Kaaya, R2
Manjurano, A4
Mosha, FW4
Cross, CL1
Portwood, NM1
Pelloquin, B2
Fullerton, K1
Walker, T2
Barker, TH1
Stone, JC1
Hasanoff, S1
Price, C1
Kabaghe, A1
Munn, Z1
Charlwood, JD2
Wright, A2
Kessy, E1
Kleinschmidt, I2
Kabera, M1
Mangala, JN1
Soebiyanto, R1
Mukarugwiro, B1
Munguti, K1
Mbituyumuremyi, A1
Lucchi, NW1
Hakizimana, E1
Sahu, SS1
Dash, S1
Sonia, T1
Gunasekaran, K1
Oumbouke, WA1
Koffi, AA1
Alou, LPA1
Camara, S1
Bayili, K1
N'Do, S1
Yadav, RS1
Namountougou, M1
Ouattara, A1
Dabiré, RK2
Ouédraogo, GA1
Diabaté, A1
Menze, BD1
Kouamo, MF1
Wondji, MJ2
Tchapga, W2
Tchoupo, M2
Kusimo, MO1
Mouhamadou, CS1
Riveron, JM2
Wondji, CS2
Ahogni, IB1
Salako, AS1
Akinro, B1
Sovi, A2
Gnanguenon, V1
Azondekon, R1
Dagnon, JF1
Akogbeto, P1
Tokponon, F1
Akogbeto, MC1
Bajunirwe, F1
Kyohere, M2
Keita, C1
Sinaba, Y1
Dicko, A1
Traore, I1
Cisse, MBM1
Koita, O1
Dengela, D1
Flatley, C1
Bankineza, E1
Mihigo, J1
Belemvire, A1
Carlson, J1
Oxborough, RM1
Meiwald, A1
Clark, E1
Kristan, M1
Jeffries, CL1
Irish, SR1
Shepard, DS1
Odumah, JU1
Awolola, ST1
Gleave, K2
Lissenden, N3
Chaplin, M1
Choi, L2
Ranson, H4
Minakawa, N1
Kongere, JO1
Sonye, GO1
Lutiali, PA1
Awuor, B1
Kawada, H1
Isozumi, R1
Futami, K1
Ten Brink, D1
Gad, M1
Ruiz, F1
Mwalimu, CD1
Kisinza, W1
Ketoh, GK1
Ahadji-Dabla, KM1
Chabi, J1
Amoudji, AD1
Apetogbo, GY1
Awokou, F1
Glitho, IA1
Toe, KH1
Müller, P1
Badolo, A1
Traore, A1
Sagnon, N1
Richardson, M1
Oruni, A1
Yeka, A2
Huijben, S1
Tchouakui, M1
Irving, H1
Cuamba, N1
Maquina, M1
Paaijmans, K1
Birhanu, A1
Asale, A1
Yewhalaw, D1
Pennetier, C1
Bouraima, A1
Chandre, F1
Piameu, M1
Etang, J1
Rossignol, M1
Sidick, I1
Zogo, B1
Lacroix, MN1
Yadav, R1
Pigeon, O2
Corbel, V1
Griffin, JT1
Worrall, E1
Yadav, S2
Mittal, PK2
Saxena, PN2
Singh, RK2
Asidi, A1
Boko, P1
Odjo, A1
Akogbeto, M1
Barik, TK1
Sharma, P1
Bhatt, RM1
Srivastava, HC1
Sreehari, U1
Dash, AP1
Barbosa, S1
Hastings, IM1
Kumar, S1
Thomas, A1
Sahgal, A1
Verma, A1
Samuel, T1
Pillai, MK1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness Study of Bednets Treated With Synegistic Combination of Insectcides in an Area With Pyrethroid-resistant Vectors in the Democratic Republic of the Congo[NCT03289663]Phase 41,680 participants (Anticipated)Interventional2017-10-02Active, not recruiting
Efficacy of Three Different Bi-treated Long Lasting Insecticidal Nets and Deployment Strategy for Control of Malaria Transmitted by Pyrethroid Resistant Vectors: A Randomised Controlled Trial[NCT03554616]4,200 participants (Actual)Interventional2019-02-01Completed
Evaluation of a Novel Long Lasting Insecticidal Net and Indoor Residual Spray Product, Separately and Together, Against Malaria Transmitted by Pyrethroid Resistant Mosquitoes.[NCT02288637]3,840 participants (Actual)Interventional2014-09-30Completed
Phase III, Open-label, Community-based, Cluster Randomised Controlled Trial to Evaluate the Efficacy, Cost-effectiveness, and Acceptability of Attractive Targeted Sugar Baits (ATSB) for Malaria Burden Reduction in Western Kenya[NCT05219565]5,376 participants (Anticipated)Interventional2022-03-01Recruiting
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda[NCT04230161]3,502 participants (Actual)Observational2020-02-24Completed
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Mozambique[NCT04716387]8,726 participants (Actual)Observational2020-08-18Completed
A Household Randomized Control Trial of Insecticide-treated Eave Nets and Window Screens for Malaria Control in Chalinze District, Tanzania.[NCT05125133]1,800 participants (Anticipated)Interventional2021-07-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for piperonyl butoxide and Malaria

ArticleYear
Effectiveness of dual active ingredient insecticide-treated nets in preventing malaria: A systematic review and meta-analysis.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Mosquito Control; Piperonyl Butoxide; Py

2023
Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: Africa; Animals; Culicidae; Drug Combinations; Feeding Behavior; Humans; Insecticide Resistance; Ins

2021
Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa.
    The Cochrane database of systematic reviews, 2018, 11-29, Volume: 11

    Topics: Africa; Animals; Culicidae; Drug Combinations; Feeding Behavior; Humans; Insecticide Resistance; Ins

2018
The impact of pyrethroid resistance on the efficacy and effectiveness of bednets for malaria control in Africa.
    eLife, 2016, 08-22, Volume: 5

    Topics: Africa; Animals; Anopheles; Biological Assay; Humans; Insecticide Resistance; Insecticide-Treated Be

2016

Trials

10 trials available for piperonyl butoxide and Malaria

ArticleYear
Effect of long-lasting insecticidal nets with and without piperonyl butoxide on malaria indicators in Uganda (LLINEUP): final results of a cluster-randomised trial embedded in a national distribution campaign.
    The Lancet. Infectious diseases, 2023, Volume: 23, Issue:2

    Topics: Animals; Child; COVID-19; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Mosquito Contr

2023
Multi-country evaluation of the durability of pyrethroid plus piperonyl-butoxide insecticide-treated nets: study protocol.
    Malaria journal, 2023, Jan-27, Volume: 22, Issue:1

    Topics: Animals; Cote d'Ivoire; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Malaria; Mosqui

2023
Differential impact of dual-active ingredient long-lasting insecticidal nets on primary malaria vectors: a secondary analysis of a 3-year, single-blind, cluster-randomised controlled trial in rural Tanzania.
    The Lancet. Planetary health, 2023, Volume: 7, Issue:5

    Topics: Animals; Anopheles; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Mosquito Con

2023
Effects of next-generation, dual-active-ingredient, long-lasting insecticidal net deployment on insecticide resistance in malaria vectors in Tanzania: an analysis of a 3-year, cluster-randomised controlled trial.
    The Lancet. Planetary health, 2023, Volume: 7, Issue:8

    Topics: Animals; Anopheles; Female; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Insecticide

2023
Effectiveness of piperonyl butoxide and pyrethroid-treated long-lasting insecticidal nets (LLINs) versus pyrethroid-only LLINs with and without indoor residual spray against malaria infection: third year results of a cluster, randomised controlled, two-by
    Malaria journal, 2023, Oct-03, Volume: 22, Issue:1

    Topics: Animals; Anopheles; Child; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Insecticides

2023
Evaluation of an alpha-cypermethrin + PBO mixture long-lasting insecticidal net VEERALIN® LN against pyrethroid resistant Anopheles gambiae s.s.: an experimental hut trial in M'bé, central Côte d'Ivoire.
    Parasites & vectors, 2019, Nov-15, Volume: 12, Issue:1

    Topics: Animals; Anopheles; Cote d'Ivoire; Disease Transmission, Infectious; Feeding Behavior; Insecticide R

2019
Effect of long-lasting insecticidal nets with and without piperonyl butoxide on malaria indicators in Uganda (LLINEUP): a pragmatic, cluster-randomised trial embedded in a national LLIN distribution campaign.
    Lancet (London, England), 2020, 04-18, Volume: 395, Issue:10232

    Topics: Animals; Anopheles; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Insecticide Re

2020
Long-Lasting Insecticidal Nets Incorporating Piperonyl Butoxide Reduce the Risk of Malaria in Children in Western Kenya: A Cluster Randomized Controlled Trial.
    The American journal of tropical medicine and hygiene, 2021, 06-14, Volume: 105, Issue:2

    Topics: Animals; Child; Child, Preschool; Culicidae; Female; Humans; Insecticide-Treated Bednets; Insecticid

2021
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two fact
    Lancet (London, England), 2018, 04-21, Volume: 391, Issue:10130

    Topics: Adolescent; Animals; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Insec

2018
LLIN Evaluation in Uganda Project (LLINEUP) - Impact of long-lasting insecticidal nets with, and without, piperonyl butoxide on malaria indicators in Uganda: study protocol for a cluster-randomised trial.
    Trials, 2019, Jun-03, Volume: 20, Issue:1

    Topics: Child; Child, Preschool; Cluster Analysis; Cross-Sectional Studies; Humans; Insecticide Resistance;

2019

Other Studies

32 other studies available for piperonyl butoxide and Malaria

ArticleYear
An Adaptive Intervention Trial Design for Finding the Optimal Integrated Strategies for Malaria Control and Elimination in Africa: A Model Simulation Study.
    The American journal of tropical medicine and hygiene, 2021, 09-07, Volume: 105, Issue:5

    Topics: Animals; Anopheles; Bacterial Toxins; Disease Eradication; Humans; Insecticide-Treated Bednets; Keny

2021
A quasi-experimental study estimating the impact of long-lasting insecticidal nets with and without piperonyl butoxide on pregnancy outcomes.
    Malaria journal, 2022, Jan-04, Volume: 21, Issue:1

    Topics: Adult; Female; Humans; Insecticide-Treated Bednets; Insecticides; Interrupted Time Series Analysis;

2022
Comparative efficacy of two pyrethroid-piperonyl butoxide nets (Olyset Plus and PermaNet 3.0) against pyrethroid resistant malaria vectors: a non-inferiority assessment.
    Malaria journal, 2022, Jan-11, Volume: 21, Issue:1

    Topics: Animals; Anopheles; Benin; Insecticide Resistance; Insecticide-Treated Bednets; Malaria; Mosquito Co

2022
Optimising the deployment of vector control tools against malaria: a data-informed modelling study.
    The Lancet. Planetary health, 2022, Volume: 6, Issue:2

    Topics: Animals; Insecticide-Treated Bednets; Malaria; Mosquito Control; Piperonyl Butoxide; Tanzania

2022
Pyrethroid-piperonyl butoxide (PBO) nets reduce the efficacy of indoor residual spraying with pirimiphos-methyl against pyrethroid-resistant malaria vectors.
    Scientific reports, 2022, 04-27, Volume: 12, Issue:1

    Topics: Animals; Anopheles; Insecticide Resistance; Malaria; Mosquito Control; Mosquito Vectors; Organothiop

2022
Assessing the impact of insecticide-treated nets in the face of insecticide resistance on malaria control.
    Journal of theoretical biology, 2022, 12-21, Volume: 555

    Topics: Adult; Animals; Culicidae; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Insecticides

2022
Malawi ICEMR Malaria Research: Interactions and Results Influencing Health Policies and Practices.
    The American journal of tropical medicine and hygiene, 2022, 10-11, Volume: 107, Issue:4_Suppl

    Topics: Adult; Animals; Child; Health Policy; Humans; Insecticide Resistance; Insecticide-Treated Bednets; M

2022
Understanding the Intransigence of Malaria in Malawi.
    The American journal of tropical medicine and hygiene, 2022, 10-11, Volume: 107, Issue:4_Suppl

    Topics: Animals; Child; Child, Preschool; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Insec

2022
East Africa International Center of Excellence for Malaria Research: Summary of Key Research Findings.
    The American journal of tropical medicine and hygiene, 2022, 10-11, Volume: 107, Issue:4_Suppl

    Topics: Adolescent; Animals; Antimalarials; Artemisinins; Carbamates; Child; Child, Preschool; Humans; Insec

2022
Laboratory and semi-field efficacy evaluation of permethrin-piperonyl butoxide treated blankets against pyrethroid-resistant malaria vectors.
    Scientific reports, 2022, 12-22, Volume: 12, Issue:1

    Topics: Animals; Anopheles; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Insecticides; Malar

2022
Impact of Pyrethroid Plus Piperonyl Butoxide Synergist-Treated Nets on Malaria Incidence 24 Months after a National Distribution Campaign in Rwanda.
    The American journal of tropical medicine and hygiene, 2023, Dec-06, Volume: 109, Issue:6

    Topics: Humans; Incidence; Insecticide Resistance; Insecticide-Treated Bednets; Insecticides; Malaria; Mosqu

2023
Synergist piperonyl butoxide enhances the efficacy of deltamethrin in deltamethrin-resistant
    The Indian journal of medical research, 2019, Volume: 149, Issue:4

    Topics: Animals; Anopheles; Drug Synergism; Humans; India; Insecticide Resistance; Insecticides; Malaria; Mo

2019
Experimental hut evaluation of DawaPlus 3.0 LN and DawaPlus 4.0 LN treated with deltamethrin and PBO against free-flying populations of Anopheles gambiae s.l. in Vallée du Kou, Burkina Faso.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Agriculture; Animals; Anopheles; Burkina Faso; Equipment Design; Flight, Animal; Gossypium; Humans;

2019
An Experimental Hut Evaluation of PBO-Based and Pyrethroid-Only Nets against the Malaria Vector
    Genes, 2020, 01-29, Volume: 11, Issue:2

    Topics: Animals; Anopheles; Cameroon; Glutathione Transferase; Insect Proteins; Insecticide Resistance; Inse

2020
Physical integrity and survivorship of long-lasting insecticidal nets distributed to households of the same socio-cultural community in Benin, West Africa.
    Malaria journal, 2020, Feb-04, Volume: 19, Issue:1

    Topics: Animals; Benin; Cohort Studies; Family Characteristics; Health Education; Humans; Informed Consent;

2020
Pyrethroid resistance in sub-Saharan Africa.
    Lancet (London, England), 2020, 04-18, Volume: 395, Issue:10232

    Topics: Africa South of the Sahara; Humans; Malaria; Piperonyl Butoxide; Pyrethrins; Uganda

2020
Anopheles gambiae (s.l.) exhibit high intensity pyrethroid resistance throughout Southern and Central Mali (2016-2018): PBO or next generation LLINs may provide greater control.
    Parasites & vectors, 2020, May-08, Volume: 13, Issue:1

    Topics: Animals; Anopheles; Biological Assay; Female; Insecticide Resistance; Insecticide-Treated Bednets; I

2020
Association of Reduced Long-Lasting Insecticidal Net Efficacy and Pyrethroid Insecticide Resistance With Overexpression of CYP6P4, CYP6P3, and CYP6Z1 in Populations of Anopheles coluzzii From Southeast Côte d'Ivoire.
    The Journal of infectious diseases, 2022, 04-19, Volume: 225, Issue:8

    Topics: Animals; Anopheles; Cote d'Ivoire; Insecticide Resistance; Insecticide-Treated Bednets; Insecticides

2022
Cost-Effectiveness of PBO versus Conventional Long-Lasting Insecticidal Bed Nets in Preventing Symptomatic Malaria in Nigeria: Results of a Pragmatic Randomized Trial.
    The American journal of tropical medicine and hygiene, 2020, 12-21, Volume: 104, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anopheles; Child; Child, Preschool; Cost-Benefi

2020
Malaria innovations: pursuing value in an evolving market.
    The Lancet. Global health, 2018, Volume: 6, Issue:2

    Topics: Animals; Diffusion of Innovation; Disease Vectors; Global Health; Humans; Insecticide Resistance; In

2018
Efficacy of two PBO long lasting insecticidal nets against natural populations of Anopheles gambiae s.l. in experimental huts, Kolokopé, Togo.
    PloS one, 2018, Volume: 13, Issue:7

    Topics: Animals; Anopheles; Genes, Insect; Humans; Insecticide Resistance; Insecticide-Treated Bednets; Inse

2018
Do bednets including piperonyl butoxide offer additional protection against populations of Anopheles gambiae s.l. that are highly resistant to pyrethroids? An experimental hut evaluation in Burkina Fasov.
    Medical and veterinary entomology, 2018, Volume: 32, Issue:4

    Topics: Animals; Anopheles; Biological Assay; Burkina Faso; DNA; Female; Housing; Humans; Insecticide Resist

2018
LLIN Evaluation in Uganda Project (LLINEUP): a cross-sectional survey of species diversity and insecticide resistance in 48 districts of Uganda.
    Parasites & vectors, 2019, Mar-12, Volume: 12, Issue:1

    Topics: Animals; Anopheles; Cross-Sectional Studies; Female; Humans; Insecticide Resistance; Insecticide-Tre

2019
Escalation of Pyrethroid Resistance in the Malaria Vector Anopheles funestus Induces a Loss of Efficacy of Piperonyl Butoxide-Based Insecticide-Treated Nets in Mozambique.
    The Journal of infectious diseases, 2019, 07-02, Volume: 220, Issue:3

    Topics: Africa; Alleles; Animals; Anopheles; Cytochrome P-450 Enzyme System; Female; Humans; Insecticide Res

2019
Bio-efficacy and physical integrity of piperonylbutoxide coated combination net (PermaNet
    Malaria journal, 2019, Jul-04, Volume: 18, Issue:1

    Topics: Animals; Anopheles; Culex; Ethiopia; Female; Insecticide Resistance; Insecticide-Treated Bednets; In

2019
Efficacy of Olyset® Plus, a new long-lasting insecticidal net incorporating permethrin and piperonyl-butoxide against multi-resistant malaria vectors [corrected].
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Anopheles; Female; Insecticide Resistance; Insecticide-Treated Bednets; Insecticides; Malar

2013
Effect of synergist piperonyl butoxide (PBO) on the toxicity of some essential oils against mosquito larvae.
    The Journal of communicable diseases, 2008, Volume: 40, Issue:4

    Topics: Animals; Culicidae; Cymbopogon; Humans; Insect Vectors; Insecticides; Larva; Malaria; Mentha piperit

2008
Effect of synergist piperonyl butoxide (PBO) on the toxicity of some essential oils against mosquito larvae.
    The Journal of communicable diseases, 2009, Volume: 41, Issue:1

    Topics: Animals; Anopheles; Cymbopogon; Humans; Insect Vectors; Lamiaceae; Larva; Lethal Dose 50; Malaria; M

2009
An experimental hut evaluation of PermaNet(®) 3.0, a deltamethrin-piperonyl butoxide combination net, against pyrethroid-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes in southern Benin.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2010, Volume: 104, Issue:12

    Topics: Animals; Anopheles; Benin; Culex; Drug Resistance; Housing; Humans; Insecticide-Treated Bednets; Ins

2010
Chlorfenapyr: a new insecticide with novel mode of action can control pyrethroid resistant malaria vectors.
    Malaria journal, 2011, Jan-25, Volume: 10

    Topics: Animals; Anopheles; DDT; Female; India; Insect Vectors; Insecticide Resistance; Insecticides; Lethal

2011
The importance of modelling the spread of insecticide resistance in a heterogeneous environment: the example of adding synergists to bed nets.
    Malaria journal, 2012, Aug-02, Volume: 11

    Topics: Animals; Anopheles; Gene Frequency; Genes, Insect; Humans; Insecticide Resistance; Insecticides; Log

2012
Variations in the insecticide-resistance spectrum of Anopheles stephensi after selection with deltamethrin or a deltamethrin-piperonyl-butoxide combination.
    Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:8

    Topics: Animals; Anopheles; DDT; Disease Vectors; Drug Combinations; Insecticide Resistance; Insecticides; L

2004