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piperonyl butoxide and Body Weight

piperonyl butoxide has been researched along with Body Weight in 28 studies

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Piperonyl butoxide was administered to pregnant mice by gavage at a level of 0 (control), 1065, 1385 and 1800 mg/kg body weight only on day 9 of gestation."3.69Developmental toxicity evaluation of piperonyl butoxide in CD-1 mice. ( Fujitani, T; Oishi, S; Takahashi, O; Tanaka, T, 1994)
" Adverse clinical observations (urogenital wetness and staining) occurred in the 1000 mg/kg/day dose group."1.72Developmental and reproduction toxicity of piperonyl butoxide part 1 developmental safety of piperonyl butoxide in the CD® (Sprague Dawley) rat. ( Hauswirth, JW; Hoberman, AM, 2022)
" As a result, the findings showed that although pyrethroids are considered to be of low acute toxicity, they become more toxic when combined with piperonyl butoxide or tetramethrin in certain doses."1.36Repeated-dose 14-day dermal toxicity of different combinations of some synthetic pyrethroid insecticides, piperonyl butoxide, and tetramethrin in rats. ( Aksoy, A; Atmaca, E; Cenesiz, M; Das, YK; Gulbahar, MY; Guvenc, D; Yarim, GF; Yavuz, O, 2010)
"Piperonyl butoxide (PBO) is a pesticide synergist used with pyrethroids as a domestic insecticide, and it acts as a non-genotoxic hepatocarcinogen in rats and mice."1.36Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice. ( Dewa, Y; Harada, T; Ishii, Y; Kawai, M; Kemmochi, S; Mitsumori, K; Nishimura, J; Saegusa, Y; Shibutani, M; Umemura, T, 2010)
" PB pretreatment also enhanced some monitored renal effects of a toxic dose (0."1.29Effect of microsomal enzyme modulators on N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS)-induced nephrotoxicity in the Fischer 344 rat. ( Anestis, DK; Beers, KW; Brown, PI; Nicoll, DW; Rankin, GO, 1993)
"Pretreatment with phenobarbital, piperonyl butoxide (2 h), SKF 525-A, or small multiple doses of OOS protected against the OOS-induced elevated level of bronchopulmonary lavage LDH, and the other signs of delayed toxicity including morphological alteration of Clara cells."1.27Effect of drug metabolism inducer and inhibitor on O,O,S-trimethyl phosphorothioate-induced delayed toxicity in rats. ( Fukuto, TR; Gandy, J; Hasegawa, L; Imamura, T, 1983)
"Piperonyl butoxide (PB) is a widely used pesticidal synergist which inhibits many mammalian detoxification reactions."1.26Potentiation of methylmercury toxicity by piperonyl butoxide. ( Eaton, LR; Friedman, MA, 1978)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19906 (21.43)18.7374
1990's12 (42.86)18.2507
2000's3 (10.71)29.6817
2010's5 (17.86)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Hoberman, AM2
Hauswirth, JW2
Sakamoto, Y1
Inoue, K2
Takahashi, M4
Taketa, Y2
Kodama, Y1
Nemoto, K1
Degawa, M1
Gamou, T1
Ozawa, S1
Nishikawa, A1
Yoshida, M2
Hayashi, S1
Matsuo, S1
Irie, K1
Watanabe, G1
Tanaka, T4
Inomata, A1
Muguruma, M2
Kawai, M3
Dewa, Y3
Nishimura, J4
Saegusa, Y3
Yasuno, H1
Jin, M3
Matsumoto, S1
Takabatake, M1
Arai, K1
Mitsumori, K5
Harada, T2
Shibutani, M2
Yavuz, O1
Aksoy, A1
Das, YK1
Gulbahar, MY1
Yarim, GF1
Cenesiz, M1
Atmaca, E1
Guvenc, D1
Kemmochi, S1
Ishii, Y1
Umemura, T1
Kashida, Y1
Moto, M1
Yokouchi, Y1
Morse, CC1
Boyd, MR1
Witschi, H1
Davis, ME1
Imamura, T1
Hasegawa, L1
Gandy, J1
Fukuto, TR1
Morrison, DG1
Foil, LD1
Takahashi, O3
Oishi, S3
Fujitani, T5
Yoneyama, M3
Hashimoto, Y1
Beers, KW1
Nicoll, DW1
Anestis, DK1
Brown, PI1
Rankin, GO1
Tada, Y1
Valentovic, MA1
Ball, JG1
Anestis, D1
Madan, E1
Phillips, JC1
Price, RJ1
Cunninghame, ME1
Osimitz, TG2
Cockburn, A1
Gabriel, KL2
Preiss, FJ2
Butler, WH2
Lake, BG1
Okamiya, H1
Onodera, H1
Ito, S1
Imazawa, T1
Yasuhara, K1
Kennedy, GL1
Smith, SH1
Kinoshita, FK1
Keplinger, ML1
Calandra, JC1
Friedman, MA1
Eaton, LR1
Dahlström-King, L1
Couture, J1
Plaa, GL1
Ando, H1
Fujitani, K1
Ikeda, T1
Kojima, A1
Kubo, Y1
Ogata, A1
Takahashi, H1
Goldstein, JA1
Hickman, P1
Kimbrough, RD1

Other Studies

28 other studies available for piperonyl butoxide and Body Weight

ArticleYear
Developmental and reproduction toxicity of piperonyl butoxide part 1 developmental safety of piperonyl butoxide in the CD® (Sprague Dawley) rat.
    Reproductive toxicology (Elmsford, N.Y.), 2022, Volume: 112

    Topics: Animals; Body Weight; Female; Fetal Weight; Fetus; Piperonyl Butoxide; Pregnancy; Rats; Rats, Spragu

2022
Developmental and reproduction toxicity of piperonyl butoxide part 3 two generation (two litter) reproduction study of piperonyl butoxide administered in the diet to CD ® (Sprague Dawley) rats.
    Reproductive toxicology (Elmsford, N.Y.), 2022, Volume: 113

    Topics: Animals; Body Weight; Diet; Female; Insecticides; Male; Piperonyl Butoxide; Rats; Rats, Sprague-Dawl

2022
Different pathways of constitutive androstane receptor-mediated liver hypertrophy and hepatocarcinogenesis in mice treated with piperonyl butoxide or decabromodiphenyl ether.
    Toxicologic pathology, 2013, Volume: 41, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Body Weight; Cell Proliferation; Constitutive Androstane Rec

2013
Effects of pyperonyl butoxide on the female reproductive tract in rats.
    The Journal of toxicological sciences, 2013, Volume: 38, Issue:6

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrous

2013
Effects of Maternal Exposure to Piperonyl Butoxide (PBO) on Behavioral Development in F1-Generation Mice.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2015, Volume: 104, Issue:6

    Topics: Animals; Behavior, Animal; Body Weight; Crosses, Genetic; Exploratory Behavior; Feeding Behavior; Fe

2015
Threshold dose of piperonyl butoxide that induces reactive oxygen species-mediated hepatocarcinogenesis in rats.
    Archives of toxicology, 2009, Volume: 83, Issue:2

    Topics: Animals; Body Weight; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Gene Expres

2009
Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice.
    Toxicologic pathology, 2009, Volume: 37, Issue:6

    Topics: Activating Transcription Factor 3; Animals; Body Weight; Carcinogenicity Tests; Cyclin D; Diethylnit

2009
Repeated-dose 14-day dermal toxicity of different combinations of some synthetic pyrethroid insecticides, piperonyl butoxide, and tetramethrin in rats.
    Cutaneous and ocular toxicology, 2010, Volume: 29, Issue:1

    Topics: Administration, Cutaneous; Animals; Biomarkers; Body Weight; Dose-Response Relationship, Drug; Drug

2010
Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice.
    Archives of toxicology, 2010, Volume: 84, Issue:2

    Topics: Animals; Body Weight; Cell Proliferation; Immunohistochemistry; Liver; Liver Neoplasms, Experimental

2010
Molecular pathological analysis for determining the possible mechanism of piperonyl butoxide-induced hepatocarcinogenesis in mice.
    Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3

    Topics: Animals; Antigens, Nuclear; Body Weight; Carcinogens; Cyclin D1; Cytochrome P-450 Enzyme System; Die

2006
The effect of 3-methylfuran inhalation exposure on the rat nasal cavity.
    Toxicology, 1984, Apr-02, Volume: 30, Issue:3

    Topics: Animals; Atmosphere Exposure Chambers; Body Weight; Drug Interactions; Epithelium; Female; Furans; I

1984
Changes of hexachlorobutadiene nephrotoxicity after piperonyl butoxide treatment.
    Toxicology, 1984, Apr-02, Volume: 30, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Butadienes; Creatinine; Drug Interactions; Glomerular Fil

1984
Effect of drug metabolism inducer and inhibitor on O,O,S-trimethyl phosphorothioate-induced delayed toxicity in rats.
    Chemico-biological interactions, 1983, Jul-01, Volume: 45, Issue:1

    Topics: Animals; Body Weight; L-Lactate Dehydrogenase; Lethal Dose 50; Lung; Male; Organothiophosphates; Org

1983
Effect of horn fly (Diptera: Muscidae) control during the spring on calf production by fall-calving beef cows.
    Journal of economic entomology, 1995, Volume: 88, Issue:1

    Topics: Animals; Body Weight; Cattle; Female; Insect Control; Muscidae; Piperonyl Butoxide; Pregnancy; Repro

1995
Piperonyl butoxide induces hepatocellular carcinoma in male CD-1 mice.
    Archives of toxicology, 1994, Volume: 68, Issue:7

    Topics: Animals; Body Weight; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred ICR; Piperonyl Butoxid

1994
Developmental toxicity evaluation of piperonyl butoxide in CD-1 mice.
    Toxicology letters, 1994, Volume: 71, Issue:2

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Behavior, Animal; Body Weight; Dose-Resp

1994
Subacute toxicity of piperonyl butoxide in ICR mice.
    Toxicology, 1993, Oct-25, Volume: 83, Issue:1-3

    Topics: Animals; Blood Proteins; Body Weight; Cholesterol; Female; Liver; Male; Mice; Mice, Inbred ICR; Orga

1993
Effect of microsomal enzyme modulators on N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS)-induced nephrotoxicity in the Fischer 344 rat.
    Toxicology, 1993, Nov-12, Volume: 84, Issue:1-3

    Topics: Animals; Body Weight; Cobalt; Drug Synergism; Fungicides, Industrial; Injections, Intraperitoneal; K

1993
Hepatotoxicity of piperonyl butoxide in male F344 rats.
    Toxicology, 1993, Nov-12, Volume: 84, Issue:1-3

    Topics: Administration, Oral; Animals; Body Weight; Dose-Response Relationship, Drug; Kidney; Liver; Male; O

1993
Modification of P450 activity and its effect on 1,2-dichlorobenzene toxicity in Fischer 344 rats.
    Toxicology, 1993, May-24, Volume: 79, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Blood Urea Nitrogen; Body Weight; Chlorobenzenes; Drug

1993
Effect of piperonyl butoxide on cell replication and xenobiotic metabolism in the livers of CD-1 mice and F344 rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 38, Issue:1

    Topics: Administration, Oral; Animals; Antimetabolites; Body Weight; Bromodeoxyuridine; Cell Division; Cytoc

1997
Oncogenicity studies of piperonyl butoxide in rats and mice.
    Human & experimental toxicology, 1998, Volume: 17, Issue:6

    Topics: Adenoma, Liver Cell; Administration, Oral; Animals; Body Weight; Carcinogenicity Tests; Carcinogens;

1998
Mechanistic study on liver tumor promoting effects of piperonyl butoxide in rats.
    Archives of toxicology, 1998, Volume: 72, Issue:11

    Topics: Animals; Body Weight; Carcinogens; Cell Division; Connexins; Cytochrome P-450 CYP2B1; Eating; Gap Ju

1998
Teratogenic evaluation of piperonyl butoxide in the rat.
    Food and cosmetics toxicology, 1977, Volume: 15, Issue:4

    Topics: Animals; Body Weight; Corpus Luteum; Female; Fetus; Organ Size; Piperonyl Butoxide; Pregnancy; Rats;

1977
Potentiation of methylmercury toxicity by piperonyl butoxide.
    Bulletin of environmental contamination and toxicology, 1978, Volume: 20, Issue:1

    Topics: Animals; Body Weight; Diet; Drug Synergism; Male; Methylmercury Compounds; Piperonyl Butoxide; Rats;

1978
Influence of agents affecting monooxygenase activity on taurolithocholic acid-induced cholestasis.
    Toxicology letters, 1992, Volume: 63, Issue:3

    Topics: Animals; Bile; Body Weight; Chlordecone; Cholestasis; Cobalt; Cytochrome P-450 Enzyme Inhibitors; Cy

1992
Sub-acute toxicity of piperonyl butoxide in F344 rats.
    Toxicology, 1992, Volume: 72, Issue:3

    Topics: Animals; Body Weight; Drinking Behavior; Feeding Behavior; Female; Kidney; Liver; Male; Organ Size;

1992
Effects of purified and technical piperonyl butoxide on drug-metabolizing enzymes and ultrastructure of rat liver.
    Toxicology and applied pharmacology, 1973, Volume: 26, Issue:3

    Topics: Aniline Compounds; Animals; Appetite; Body Weight; Cytochrome P-450 Enzyme System; Diet; Endoplasmic

1973