piperidines has been researched along with Pneumonia--Staphylococcal* in 1 studies
1 other study(ies) available for piperidines and Pneumonia--Staphylococcal
| Article | Year |
|---|---|
Synthesis and antibacterial activities of new piperidine substituted (5R)-[1,2,3]triazolylmethyl and (5R)-[(4-F-[1,2,3]triazolyl)methyl] oxazolidinones.
A novel series of 5(R)-[1,2,3]triazolylmethyl and (5R)-[(4-F-[1,2,3]triazolyl)methyl]oxazolidinones having various piperidine group were synthesized and evaluated antibacterial activity against clinically isolated resistant strains of Gram-positive and Gram-negative bacteria. The compound 12a having exo-cyanoethylidene group in the 4-position of piperidine ring was found to be two to threefold more potent than the linezolid against penicillin-resistant Staphylococcus pneumonia and Staphylococcus agalactiae, and also exhibited reduced MAO-B inhibitory activity. Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Oxazolidinones; Piperidines; Pneumonia, Staphylococcal; Staphylococcus; Structure-Activity Relationship | 2013 |