piperidines and Neglected-Diseases

piperidines has been researched along with Neglected-Diseases* in 1 studies

Other Studies

1 other study(ies) available for piperidines and Neglected-Diseases

Article	Year
Targeting the Mycobacterium ulcerans cytochrome bc Nature communications, 2018, 12-18, Volume: 9, Issue:1 Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc Topics: Africa; Animals; Antibiotics, Antitubercular; Australia; Buruli Ulcer; Disease Models, Animal; Electron Transport Complex III; Electron Transport Complex IV; Female; Humans; Imidazoles; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Mycobacterium ulcerans; Neglected Diseases; Piperidines; Pyridines; Rifampin; Treatment Outcome	2018

Article

Year

Targeting the Mycobacterium ulcerans cytochrome bc

Nature communications, 2018, 12-18, Volume: 9, Issue:1

Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc

Topics: Africa; Animals; Antibiotics, Antitubercular; Australia; Buruli Ulcer; Disease Models, Animal; Electron Transport Complex III; Electron Transport Complex IV; Female; Humans; Imidazoles; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Mycobacterium ulcerans; Neglected Diseases; Piperidines; Pyridines; Rifampin; Treatment Outcome

2018