Page last updated: 2024-11-02

piperazine and Diabetes Mellitus, Type 2

piperazine has been researched along with Diabetes Mellitus, Type 2 in 4 studies

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taha, M1
Irshad, M1
Imran, S1
Chigurupati, S1
Selvaraj, M1
Rahim, F1
Ismail, NH1
Nawaz, F1
Khan, KM1
Kushwaha, RN1
Srivastava, R1
Mishra, A1
Rawat, AK1
Srivastava, AK1
Haq, W1
Katti, SB1
Sharma, R1
Sun, H1
Piotrowski, DW1
Ryder, TF1
Doran, SD1
Dai, H1
Prakash, C1
Yoshida, T1
Sakashita, H1
Akahoshi, F1
Hayashi, Y1

Other Studies

4 other studies available for piperazine and Diabetes Mellitus, Type 2

ArticleYear
Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study.
    European journal of medicinal chemistry, 2017, Dec-01, Volume: 141

    Topics: alpha-Amylases; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Huma

2017
Design, synthesis, biological screening, and molecular docking studies of piperazine-derived constrained inhibitors of DPP-IV for the treatment of type 2 diabetes.
    Chemical biology & drug design, 2015, Volume: 85, Issue:4

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV I

2015
Metabolism, excretion, and pharmacokinetics of ((3,3-difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, a dipeptidyl peptidase inhibitor, in rat, dog and human.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:11

    Topics: Amides; Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Di

2012
[(S)-gamma-(4-Aryl-1-piperazinyl)-l-prolyl]thiazolidines as a novel series of highly potent and long-lasting DPP-IV inhibitors.
    Bioorganic & medicinal chemistry letters, 2007, May-01, Volume: 17, Issue:9

    Topics: Animals; Chemistry, Pharmaceutical; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; D

2007