piperazine has been researched along with Dementia Praecox in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Schizophrenia is a chronic mental disorder that is not satisfactorily treated with available antipsychotics." | 5.91 | Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation. ( Bartyzel, A; Budzyńska, B; Castro, M; Chodkowski, A; Fornal, E; Kaczor, AA; Mirecka, K; Stępnicki, P; Szałaj, K; Targowska-Duda, KM; Turło, J; Wróbel, MZ; Wróbel, TM; Wronikowska-Denysiuk, O; Zięba, A, 2023) |
| "Schizophrenia is a chronic mental disorder that is not satisfactorily treated with available antipsychotics." | 1.91 | Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation. ( Bartyzel, A; Budzyńska, B; Castro, M; Chodkowski, A; Fornal, E; Kaczor, AA; Mirecka, K; Stępnicki, P; Szałaj, K; Targowska-Duda, KM; Turło, J; Wróbel, MZ; Wróbel, TM; Wronikowska-Denysiuk, O; Zięba, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stępnicki, P | 1 |
| Wronikowska-Denysiuk, O | 1 |
| Zięba, A | 1 |
| Targowska-Duda, KM | 1 |
| Bartyzel, A | 1 |
| Wróbel, MZ | 1 |
| Wróbel, TM | 1 |
| Szałaj, K | 1 |
| Chodkowski, A | 1 |
| Mirecka, K | 1 |
| Budzyńska, B | 1 |
| Fornal, E | 1 |
| Turło, J | 1 |
| Castro, M | 1 |
| Kaczor, AA | 1 |
| Huang, L | 1 |
| Gao, L | 1 |
| Zhang, X | 1 |
| Yin, L | 1 |
| Hu, J | 1 |
| Song, T | 1 |
| Chen, Y | 2 |
| Cao, X | 1 |
| Zhang, Y | 1 |
| Qiu, Y | 1 |
| Yu, M | 1 |
| Xu, X | 1 |
| Liu, X | 1 |
| Liu, BF | 1 |
| Zhang, L | 2 |
| Zhang, G | 1 |
| Xiong, H | 1 |
| Brugel, TA | 1 |
| Balestra, M | 1 |
| Brown, DG | 1 |
| Brush, KA | 1 |
| Hightower, C | 1 |
| Hinkley, L | 1 |
| Hoesch, V | 1 |
| Kang, J | 1 |
| Koether, GM | 1 |
| McCauley, JP | 1 |
| McLaren, FM | 1 |
| Panko, LM | 1 |
| Simpson, TR | 1 |
| Smith, RW | 1 |
| Woods, JM | 1 |
| Brockel, B | 1 |
| Chhajlani, V | 1 |
| Gadient, RA | 1 |
| Spear, N | 1 |
| Sygowski, LA | 1 |
| Zhang, M | 1 |
| Arora, J | 1 |
| Breysse, N | 1 |
| Wilson, JM | 1 |
| Isaac, M | 1 |
| Slassi, A | 1 |
| King, MM | 1 |
| Johnson, DS | 1 |
| Choi, C | 1 |
| Fay, LK | 1 |
| Favor, DA | 1 |
| Repine, JT | 1 |
| White, AD | 1 |
| Akunne, HC | 1 |
| Fitzgerald, L | 1 |
| Nicholls, K | 1 |
| Snyder, BJ | 1 |
| Whetzel, SZ | 1 |
| Serpa, KA | 1 |
5 other studies available for piperazine and Dementia Praecox
| Article | Year |
|---|---|
Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation.
Topics: Antipsychotic Agents; Dopamine; Humans; Indazoles; Ligands; Piperazine; Receptor, Serotonin, 5-HT1A; | 2023 |
Synthesis and pharmacological evaluation of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
Topics: Amides; Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Cha | 2020 |
Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.
Topics: Animals; Antipsychotic Agents; Body Weight; Chemistry Techniques, Synthetic; Drug Design; Ether-A-Go | 2018 |
4-aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators.
Topics: Allosteric Regulation; Amides; Humans; Microsomes, Liver; Piperazine; Piperazines; Piperidines; Rece | 2010 |
Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder.
Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Drug Discovery; Haplorhini; Male; Molecular Structu | 2011 |