piperazine has been researched along with Absence Seizure in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " This compound was effective in delaying onset of PTZ-evoked seizures at the dose of 5mg/kg in kindled animals and significantly reduced oxidative stress better than standard drug phenobarbital (PB)." | 3.81 | Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents. ( Kumari, S; Mishra, CB; Tiwari, M, 2015) |
| "BPPU also successfully inhibited seizures induced by 3-mercaptopropionic acid (3-MPA) and thiosemicarbazide (TSC) in mice thus, suggested that BPPU might influence GABA-ergic neurotransmission in the brain." | 1.43 | Pharmacological evaluation of novel 1-[4-(4-benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-phenyl]-3-phenyl-urea as potent anticonvulsant and antidepressant agent. ( Kumari, S; Mishra, CB; Tiwari, M, 2016) |
| " Combining of xanthone with piperazine moiety resulted in obtaining of compounds with increased bioavailability after oral administration." | 1.39 | Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety. ( Bojarski, AJ; Gunia, A; Marona, H; Pytka, K; Satała, G; Siwek, A; Szkaradek, N; Szneler, E; Waszkielewicz, AM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Archana, A | 1 |
| Rybka, S | 1 |
| Obniska, J | 1 |
| Żmudzki, P | 1 |
| Koczurkiewicz, P | 1 |
| Wójcik-Pszczoła, K | 1 |
| Pękala, E | 1 |
| Bryła, A | 1 |
| Rapacz, A | 1 |
| Szczepańska, K | 1 |
| Karcz, T | 1 |
| Mogilski, S | 1 |
| Siwek, A | 2 |
| Kuder, KJ | 1 |
| Latacz, G | 1 |
| Kubacka, M | 1 |
| Hagenow, S | 1 |
| Lubelska, A | 1 |
| Olejarz, A | 1 |
| Kotańska, M | 1 |
| Sadek, B | 1 |
| Stark, H | 1 |
| Kieć-Kononowicz, K | 1 |
| Waszkielewicz, AM | 1 |
| Gunia, A | 1 |
| Szkaradek, N | 1 |
| Pytka, K | 1 |
| Satała, G | 1 |
| Bojarski, AJ | 1 |
| Szneler, E | 1 |
| Marona, H | 1 |
| Kumari, S | 2 |
| Mishra, CB | 2 |
| Tiwari, M | 2 |
| SCHUCH, P | 1 |
| STEPHAN, U | 1 |
| JACOBI, G | 1 |
| LAUBIE, M | 1 |
| LEDOUAREC, JC | 1 |
| SCHMITT, H | 1 |
| SAWIUK, S | 1 |
| KOBYLARZ, A | 1 |
9 other studies available for piperazine and Absence Seizure
| Article | Year |
|---|---|
Synthesis of Novel Triazolyl/Oxadiazolyl/Thiadiazolyl-Piperazine as Potential Anticonvulsant Agents.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Female; Humans; Male; Mice; Oxadiazoles; Piperazin | 2021 |
Synthesis and Determination of Lipophilicity, Anticonvulsant Activity, and Preliminary Safety of 3-Substituted and 3-Unsubstituted N-[(4-Arylpiperazin-1-yl)alkyl]pyrrolidine-2,5-dione Derivatives.
Topics: Animals; Anticonvulsants; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Disease Models, | 2017 |
Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H
Topics: Animals; Dose-Response Relationship, Drug; Electroshock; Histamine H3 Antagonists; Humans; Ligands; | 2018 |
Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety.
Topics: Administration, Oral; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electroshock; Half-Lif | 2013 |
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carbamates; Drug Design; Electroshock; Epilepsy; Mice; Pentylenetetrazole; | 2015 |
Pharmacological evaluation of novel 1-[4-(4-benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-phenyl]-3-phenyl-urea as potent anticonvulsant and antidepressant agent.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Antidepressive Agents; Disease Models, Animal; E | 2016 |
[Side-effects of anthelmintic piperazine preparations].
Topics: Anthelmintics; Ascariasis; Electroencephalography; Humans; Oxyuriasis; Piperazine; Piperazines; Pipe | 1963 |
[EXPERIMENTAL RESEARCH ON A NEW SYNTHETIC CORONARY DILATOR: BENZYDRYL-1-PIPERONYL PIPERAZINE].
Topics: Anesthesia; Anesthesia, Intravenous; Barbiturates; Behavior, Animal; Blood Circulation; Blood Flow V | 1964 |
[CEREBRAL MANIFESTATIONS IN PIPERAZINE POISONING IN A 3-YEAR-OLD BOY].
Topics: Brain Diseases; Child; Humans; Male; Piperazine; Piperazines; Poisoning; Seizures; Toxicology | 1964 |