piperacillin--tazobactam-drug-combination and Lupus-Erythematosus--Systemic

Roseomonas mucosa, as a Gram-negative coccobacilli, is an opportunistic pathogen that has rarely been reported in human infections. Here we describe a case of bacteremia in an infective endocarditis patient with systemic lupus erythematosus (SLE).. A 44-year-old female patient with SLE suffered bacteremia caused by Roseomonas mucosa complicated with infective endocarditis (IE). The patient started on treatment with piperacillin-tazobactam and levofloxacin against Roseomonas mucosa, which was switched after 4 days to meropenem and amikacin for an additional 2 weeks. She had a favorable outcome with a 6-week course of intravenous antibiotic therapy.. Roseomonas mucosa is rarely reported in IE patients; therefore, we report the case in order to improve our ability to identify this pathogen and expand the range of known bacterial causes of infective endocarditis.

Topics: Adult; Amikacin; Anti-Bacterial Agents; Bacteremia; Endocarditis; Endocarditis, Bacterial; Female; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Lupus Erythematosus, Systemic; Methylobacteriaceae; Piperacillin, Tazobactam Drug Combination

Topics: Administration, Intravenous; Anti-Bacterial Agents; Blood Culture; Cellulitis; Female; Glucocorticoids; Humans; Leg; Lupus Erythematosus, Systemic; Middle Aged; Piperacillin, Tazobactam Drug Combination; Prednisolone; Prognosis; Pseudomonas Infections; Pseudomonas putida

A 31-year-old woman with systemic lupus erythematosus presented to the emergency department with cough for 1 week. Chest radiograph demonstrated cavitating lesion in the right upper zone with surrounding ground-glass change. Blood culture results from the day of hospital presentation grew

Topics: Adult; Anti-Bacterial Agents; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Lung Diseases; Lupus Erythematosus, Systemic; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tomography, X-Ray Computed