piperacillin--tazobactam-drug-combination and Headache

Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological entity, associated with a vast array of medical conditions and a variety of presenting symptoms. There is a characteristic pattern of radiographic features alongside suggestive clinical manifestations, which lead to a diagnosis of PRES. This report describes the case of a 39 years old, previously normotensive woman, who presented on day 7 postpartum with generalised tonic clonic seizures, reduced conscious level and a history of blurred vision and headache. She was treated immediately as eclamptic and transferred to the intensive care unit for stabilisation. Following an inconclusive CT result, an MRI was performed 2 days after presentation, which demonstrated white matter changes consistent with those found in PRES. She made a full recovery and a repeat MRI scan 7 weeks later showed no progression of the lesions noted on the original scan.

Topics: Adult; Anti-Bacterial Agents; Antihypertensive Agents; Critical Care; Diagnosis, Differential; Female; Fluid Therapy; Follow-Up Studies; Headache; Humans; Labetalol; Magnesium Sulfate; Magnetic Resonance Imaging; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Posterior Leukoencephalopathy Syndrome; Postpartum Period; Seizures; Sepsis; Tomography, X-Ray Computed; Treatment Outcome